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The map label for this gene is rocD [H]

Identifier: 146302384

GI number: 146302384

Start: 5633823

End: 5635076

Strand: Reverse

Name: rocD [H]

Synonym: Fjoh_4657

Alternate gene names: 146302384

Gene position: 5635076-5633823 (Counterclockwise)

Preceding gene: 146302389

Following gene: 146302383

Centisome position: 92.43

GC content: 37.0

Gene sequence:

>1254_bases
ATGGCAAATACTCAAGAAATACTTTCGTCAAAATCAGAAGTTTTGATTGAAAAAGAGAATAAATACGGAGCACATAACTA
TCATCCGCTTCCTGTAGTGTTAGAAAAAGGAGAAGGTGTTTATGTATGGGATGTTGACGGGAAAAGATATTATGACTTCT
TATCTGCTTATTCTGCTGTAAATCAAGGACACTGCCATCCAAAAATTGTGAAAGCAATGATAGATCAGGCACAGACCTTA
ACGCTTACATCTCGTGCTTTTTACAATGATAAACTAGGAAACTACGAAGAATACGTTACAAAATATTTCGGTTTTGATAA
AGTACTGCCAATGAATACAGGTGCAGAAGCTGTTGAAACTGCACTAAAAGTATCCAGAAAATGGGCTTATGAAGTAAAAG
GAATTCCTGAAAATCAGGCGCAGATTATTGTATGCGAGAATAATTTTCACGGAAGAACAACGACAATCATTTCATTTTCT
AACGACGAAACAGCCCGTAAAAACTTTGGTCCGTTTACAGATGGATTTATAAAAATTGAATACGATAATCTTGAAGCCCT
TGAAAAAGCTTTAGAATCATCAAAAAATATTGCCGGATTTTTAGTTGAACCTATTCAGGGAGAAGCCGGAGTTTATGTGC
CAAGTGAAGGATATTTAGCAAAAGCAAAAGCATTATGCGAAAAGCACAATGTTTTGTTTATTGCAGATGAGGTTCAAACC
GGAATTGCACGTACCGGAAAATTATTAGCTGTTCACCACGAAAATGTACAGCCGGATATCCTGATTTTAGGAAAAGCAAT
TTCTGGCGGCGTTTATCCGGTTTCGGCAGTTTTATGTAATAATGAAATCATGAATGTTATCAAGCCGGGTCAGCATGGAT
CTACTTTTGGAGGAAATCCAGTTGCGGCAGCGGTTGCGATTGCAGCTCTTGAAGTGGTAAAAGACGAAAAATTAGCCGAA
AATGCAGAACGTTTAGGAATAATTCTAAGAGAAGGGTTAAACAAGATTGCCGAAAAGAATGACTTAATTACGCTGGTTCG
CGGTAAAGGACTTTTGAATGCAATTGTAATTAACAGCGGCGAAGATTCTGATTTGGCTTGGGAGATCTGCTTGAAATTTA
GAGATAACGGATTACTGGCAAAACCAACACACGGAAACAAAATTAGATTTGCACCGCCATTGGTAATGACAGAAGAACAA
ATTAAGGAATGTCTTGAAATTATCGAGAAATCTTTAAACGAGTTTAAAAACTAA

Upstream 100 bases:

>100_bases
TATATTTATTTTTTAAAACTAAAATAAGGTTAAAAATGTTTGATTTTTGTTCTTAAATAAATAATTTTTATATTTTTGTT
TCAGAAAAAATAAAATTATC

Downstream 100 bases:

>100_bases
ATTCAGTTGCAATTATAAAAGGTACAGCTGCGAAAATCTTTCGCAGCTGTTTTGTTTTTTGGCAAATTGGAATTATATAA
TGAAGTGTATTAATTATATA

Product: ornithine aminotransferase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MANTQEILSSKSEVLIEKENKYGAHNYHPLPVVLEKGEGVYVWDVDGKRYYDFLSAYSAVNQGHCHPKIVKAMIDQAQTL
TLTSRAFYNDKLGNYEEYVTKYFGFDKVLPMNTGAEAVETALKVSRKWAYEVKGIPENQAQIIVCENNFHGRTTTIISFS
NDETARKNFGPFTDGFIKIEYDNLEALEKALESSKNIAGFLVEPIQGEAGVYVPSEGYLAKAKALCEKHNVLFIADEVQT
GIARTGKLLAVHHENVQPDILILGKAISGGVYPVSAVLCNNEIMNVIKPGQHGSTFGGNPVAAAVAIAALEVVKDEKLAE
NAERLGIILREGLNKIAEKNDLITLVRGKGLLNAIVINSGEDSDLAWEICLKFRDNGLLAKPTHGNKIRFAPPLVMTEEQ
IKECLEIIEKSLNEFKN

Sequences:

>Translated_417_residues
MANTQEILSSKSEVLIEKENKYGAHNYHPLPVVLEKGEGVYVWDVDGKRYYDFLSAYSAVNQGHCHPKIVKAMIDQAQTL
TLTSRAFYNDKLGNYEEYVTKYFGFDKVLPMNTGAEAVETALKVSRKWAYEVKGIPENQAQIIVCENNFHGRTTTIISFS
NDETARKNFGPFTDGFIKIEYDNLEALEKALESSKNIAGFLVEPIQGEAGVYVPSEGYLAKAKALCEKHNVLFIADEVQT
GIARTGKLLAVHHENVQPDILILGKAISGGVYPVSAVLCNNEIMNVIKPGQHGSTFGGNPVAAAVAIAALEVVKDEKLAE
NAERLGIILREGLNKIAEKNDLITLVRGKGLLNAIVINSGEDSDLAWEICLKFRDNGLLAKPTHGNKIRFAPPLVMTEEQ
IKECLEIIEKSLNEFKN
>Mature_416_residues
ANTQEILSSKSEVLIEKENKYGAHNYHPLPVVLEKGEGVYVWDVDGKRYYDFLSAYSAVNQGHCHPKIVKAMIDQAQTLT
LTSRAFYNDKLGNYEEYVTKYFGFDKVLPMNTGAEAVETALKVSRKWAYEVKGIPENQAQIIVCENNFHGRTTTIISFSN
DETARKNFGPFTDGFIKIEYDNLEALEKALESSKNIAGFLVEPIQGEAGVYVPSEGYLAKAKALCEKHNVLFIADEVQTG
IARTGKLLAVHHENVQPDILILGKAISGGVYPVSAVLCNNEIMNVIKPGQHGSTFGGNPVAAAVAIAALEVVKDEKLAEN
AERLGIILREGLNKIAEKNDLITLVRGKGLLNAIVINSGEDSDLAWEICLKFRDNGLLAKPTHGNKIRFAPPLVMTEEQI
KECLEIIEKSLNEFKN

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=404, Percent_Identity=62.8712871287129, Blast_Score=538, Evalue=1e-153,
Organism=Homo sapiens, GI284507298, Length=305, Percent_Identity=60.983606557377, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=28.2973621103118, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13994255, Length=439, Percent_Identity=28.0182232346241, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI226442709, Length=385, Percent_Identity=28.8311688311688, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=27.3381294964029, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI24119277, Length=456, Percent_Identity=24.1228070175439, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI188536080, Length=438, Percent_Identity=26.4840182648402, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679950, Length=438, Percent_Identity=26.4840182648402, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679946, Length=438, Percent_Identity=26.4840182648402, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=34.1902313624679, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI145693181, Length=389, Percent_Identity=36.7609254498715, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=34.4647519582245, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789016, Length=453, Percent_Identity=31.5673289183223, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1787560, Length=409, Percent_Identity=32.2738386308068, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=27.1844660194175, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1786349, Length=347, Percent_Identity=28.5302593659942, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=407, Percent_Identity=57.985257985258, Blast_Score=507, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=53.7102473498233, Blast_Score=314, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI71981843, Length=177, Percent_Identity=59.8870056497175, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=29.2134831460674, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=458, Percent_Identity=28.82096069869, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17541228, Length=459, Percent_Identity=24.400871459695, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=55.0827423167849, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=32, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321456, Length=434, Percent_Identity=26.036866359447, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=454, Percent_Identity=23.1277533039648, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=403, Percent_Identity=65.7568238213399, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=28.4064665127021, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.5057471264368, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=26.6826923076923, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=26.1574074074074, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=26.1574074074074, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=26.1574074074074, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 46014; Mature: 45883

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTQEILSSKSEVLIEKENKYGAHNYHPLPVVLEKGEGVYVWDVDGKRYYDFLSAYSAV
CCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHH
NQGHCHPKIVKAMIDQAQTLTLTSRAFYNDKLGNYEEYVTKYFGFDKVLPMNTGAEAVET
CCCCCCHHHHHHHHCCCCEEEEEHHHHHCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHH
ALKVSRKWAYEVKGIPENQAQIIVCENNFHGRTTTIISFSNDETARKNFGPFTDGFIKIE
HHHHHHHHEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEE
YDNLEALEKALESSKNIAGFLVEPIQGEAGVYVPSEGYLAKAKALCEKHNVLFIADEVQT
ECCHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHCCEEEEECCHHH
GIARTGKLLAVHHENVQPDILILGKAISGGVYPVSAVLCNNEIMNVIKPGQHGSTFGGNP
HHHCCCCEEEEECCCCCCCEEEEEEHHCCCCCEEEEEEECHHHHHHCCCCCCCCCCCCCH
VAAAVAIAALEVVKDEKLAENAERLGIILREGLNKIAEKNDLITLVRGKGLLNAIVINSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECC
EDSDLAWEICLKFRDNGLLAKPTHGNKIRFAPPLVMTEEQIKECLEIIEKSLNEFKN
CCCCCEEEEEEEECCCCEEECCCCCCEEEECCCCEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANTQEILSSKSEVLIEKENKYGAHNYHPLPVVLEKGEGVYVWDVDGKRYYDFLSAYSAV
CCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHH
NQGHCHPKIVKAMIDQAQTLTLTSRAFYNDKLGNYEEYVTKYFGFDKVLPMNTGAEAVET
CCCCCCHHHHHHHHCCCCEEEEEHHHHHCCCCCCHHHHHHHHHCCCCEECCCCCHHHHHH
ALKVSRKWAYEVKGIPENQAQIIVCENNFHGRTTTIISFSNDETARKNFGPFTDGFIKIE
HHHHHHHHEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEE
YDNLEALEKALESSKNIAGFLVEPIQGEAGVYVPSEGYLAKAKALCEKHNVLFIADEVQT
ECCHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHCCEEEEECCHHH
GIARTGKLLAVHHENVQPDILILGKAISGGVYPVSAVLCNNEIMNVIKPGQHGSTFGGNP
HHHCCCCEEEEECCCCCCCEEEEEEHHCCCCCEEEEEEECHHHHHHCCCCCCCCCCCCCH
VAAAVAIAALEVVKDEKLAENAERLGIILREGLNKIAEKNDLITLVRGKGLLNAIVINSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECC
EDSDLAWEICLKFRDNGLLAKPTHGNKIRFAPPLVMTEEQIKECLEIIEKSLNEFKN
CCCCCEEEEEEEECCCCEEECCCCCCEEEECCCCEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]