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The map label for this gene is apbE [H]

Identifier: 146301806

GI number: 146301806

Start: 4859149

End: 4860156

Strand: Direct

Name: apbE [H]

Synonym: Fjoh_4070

Alternate gene names: 146301806

Gene position: 4859149-4860156 (Clockwise)

Preceding gene: 146301805

Following gene: 146301807

Centisome position: 79.7

GC content: 38.39

Gene sequence:

>1008_bases
ATGCACAAATTATTGTCACATAAATTATTAATCCTGTTTGTAATTTCCTGTTGTTTTTCAGCACATTCGCAGGTTTTACG
AAAAAGAACTACTCTGCTTATGGGCGGACGTTTTGACATTAGTATTGTGGCAAAGGATTCTCTAACTGCAGAACAAAATA
TAAACGAAGTAATTGCCGAAATTACGCGAATTGAAAACCTAATTTCTGACTGGAAACCGGATTCGCAGGTTTCTCAGGTA
AATCAAAATGCCGGAATTAAACCCATAAAAGTTGATCGCGAAGTATTTGAACTTGCACAAAGAGCTTTAAAATTATCAGA
AATAACCAACGGCGGATTTGATGTTAGTTTTGCCGCAATGGACCGAATCTGGAAATTTGACGGATCAATGACCGAAATGC
CTTCGGCGGAAGCCATAAAAAAGTCGGTTGAGAAAGTGGGTTATAAAAACATTATTTTAGATTCTGTTCAATCAACAATT
TTCTTAAAACTAAAAGGAATGAAGATTGGCTTTGGCGCTTTAGGTGAAGGTTACGCAACTGATAAATGCCGTACAATGAT
GATTGCAAAAGGCATTGAAGCCGGAATTGTAAACGGTTCGGGAGATATGAGCACCTGGGGGAAACAGCCCAACGGACAGC
CTTGGAAAATTGGAATCACAAACCCTTTTAAACCTGAAAAACTTCTGGCAGTCGTTCCCTTAAATCAAGGTGCGGTCACT
ACATCCGGGAGTTATGAAAAGTTCGTTATTTTTAACGGAAAACGATATTCTCACATTATAAATCCTGCAACCGGATATCC
TGCAACGGGCTTGTGCAGCGTGACTGTCTTTGGTCCAAATGCCGAAACCGCAAACGGATTAAGCACTTCAATGATGGTTT
TGGGACAGACAGAAGGCTTGCTTTTACTTCAAAAATTTCCAGATTACAGCTGTGTAATGATTACTGATAACGGAAAAGTT
ATTAAGTCAAAAAATTTCTCCATTAAAAAGTTCAAAGCAAAATTGTAA

Upstream 100 bases:

>100_bases
ATAGCCCCAGCGGGGCGATATATTTATAGATTAATTTAATTCATACCAAACCAAAGCCCCAGCGGGGCGGCACATATGAC
TCTTCAAATTCTTTAAAAAT

Downstream 100 bases:

>100_bases
ATTTAAGGTACTAAGATTCTAAGGTGCTGAGGCTCTAAGTTTTCAGCACGGTTTTTCATTATAACAATTACTGCTTATTT
CCAACATTAAAATCTCTAAT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MHKLLSHKLLILFVISCCFSAHSQVLRKRTTLLMGGRFDISIVAKDSLTAEQNINEVIAEITRIENLISDWKPDSQVSQV
NQNAGIKPIKVDREVFELAQRALKLSEITNGGFDVSFAAMDRIWKFDGSMTEMPSAEAIKKSVEKVGYKNIILDSVQSTI
FLKLKGMKIGFGALGEGYATDKCRTMMIAKGIEAGIVNGSGDMSTWGKQPNGQPWKIGITNPFKPEKLLAVVPLNQGAVT
TSGSYEKFVIFNGKRYSHIINPATGYPATGLCSVTVFGPNAETANGLSTSMMVLGQTEGLLLLQKFPDYSCVMITDNGKV
IKSKNFSIKKFKAKL

Sequences:

>Translated_335_residues
MHKLLSHKLLILFVISCCFSAHSQVLRKRTTLLMGGRFDISIVAKDSLTAEQNINEVIAEITRIENLISDWKPDSQVSQV
NQNAGIKPIKVDREVFELAQRALKLSEITNGGFDVSFAAMDRIWKFDGSMTEMPSAEAIKKSVEKVGYKNIILDSVQSTI
FLKLKGMKIGFGALGEGYATDKCRTMMIAKGIEAGIVNGSGDMSTWGKQPNGQPWKIGITNPFKPEKLLAVVPLNQGAVT
TSGSYEKFVIFNGKRYSHIINPATGYPATGLCSVTVFGPNAETANGLSTSMMVLGQTEGLLLLQKFPDYSCVMITDNGKV
IKSKNFSIKKFKAKL
>Mature_335_residues
MHKLLSHKLLILFVISCCFSAHSQVLRKRTTLLMGGRFDISIVAKDSLTAEQNINEVIAEITRIENLISDWKPDSQVSQV
NQNAGIKPIKVDREVFELAQRALKLSEITNGGFDVSFAAMDRIWKFDGSMTEMPSAEAIKKSVEKVGYKNIILDSVQSTI
FLKLKGMKIGFGALGEGYATDKCRTMMIAKGIEAGIVNGSGDMSTWGKQPNGQPWKIGITNPFKPEKLLAVVPLNQGAVT
TSGSYEKFVIFNGKRYSHIINPATGYPATGLCSVTVFGPNAETANGLSTSMMVLGQTEGLLLLQKFPDYSCVMITDNGKV
IKSKNFSIKKFKAKL

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=326, Percent_Identity=27.6073619631902, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36670; Mature: 36670

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKLLSHKLLILFVISCCFSAHSQVLRKRTTLLMGGRFDISIVAKDSLTAEQNINEVIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHH
ITRIENLISDWKPDSQVSQVNQNAGIKPIKVDREVFELAQRALKLSEITNGGFDVSFAAM
HHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEHHHH
DRIWKFDGSMTEMPSAEAIKKSVEKVGYKNIILDSVQSTIFLKLKGMKIGFGALGEGYAT
HHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEECEEEECCCCCCCCCC
DKCRTMMIAKGIEAGIVNGSGDMSTWGKQPNGQPWKIGITNPFKPEKLLAVVPLNQGAVT
CHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCEE
TSGSYEKFVIFNGKRYSHIINPATGYPATGLCSVTVFGPNAETANGLSTSMMVLGQTEGL
ECCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCE
LLLQKFPDYSCVMITDNGKVIKSKNFSIKKFKAKL
EEEEECCCCEEEEEECCCCEEECCCCEEEEHEECC
>Mature Secondary Structure
MHKLLSHKLLILFVISCCFSAHSQVLRKRTTLLMGGRFDISIVAKDSLTAEQNINEVIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHHHHHHHH
ITRIENLISDWKPDSQVSQVNQNAGIKPIKVDREVFELAQRALKLSEITNGGFDVSFAAM
HHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEHHHH
DRIWKFDGSMTEMPSAEAIKKSVEKVGYKNIILDSVQSTIFLKLKGMKIGFGALGEGYAT
HHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCEEEEEEECEEEECCCCCCCCCC
DKCRTMMIAKGIEAGIVNGSGDMSTWGKQPNGQPWKIGITNPFKPEKLLAVVPLNQGAVT
CHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCEE
TSGSYEKFVIFNGKRYSHIINPATGYPATGLCSVTVFGPNAETANGLSTSMMVLGQTEGL
ECCCCEEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCE
LLLQKFPDYSCVMITDNGKVIKSKNFSIKKFKAKL
EEEEECCCCEEEEEECCCCEEECCCCEEEEHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]