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The map label for this gene is cysJ [H]

Identifier: 146301805

GI number: 146301805

Start: 4856434

End: 4858617

Strand: Direct

Name: cysJ [H]

Synonym: Fjoh_4069

Alternate gene names: 146301805

Gene position: 4856434-4858617 (Clockwise)

Preceding gene: 146301804

Following gene: 146301806

Centisome position: 79.65

GC content: 35.81

Gene sequence:

>2184_bases
ATGACTCTTTCTTTCTGGCGCTACGCACATTTGGCTCTGGCCTTATTTTCTTCGATATTTCTGCTTTTAGCTTCTGTTAC
CGGAATCATTCTCGCAGTCGATGCAGTACAGGAAAAAACACTTCCGTACAAAGCTGCTGATTTTGATAAAATTACTTTAG
GAGAAACACTGCCGGTATTAAAAAAAGAATACTCAGAAATCACCGAATTGAGTGTCGATTACAATCAGTTTGTAACACTT
CAGGCCATTGATAAAGATGGAAATGATGTGAATGCTTATATTGATCCTAAAACCGGAAAAGCATTAGGAACGCCTGCAAA
AAAGAGTGAATTTATTAAATGGGTTACAAGTTTTCATCGTTCGCTGTTTCTTCATGAAACCGGCCGATTCTTTGTTGGCG
TAATTTCTTTTTGTTTACTGTTAATTTCAATTTCGGGATTTGTGCTGGTTTTAAAAAGACAAAGAGGCATCCGTAATTTC
TTTTCGAAAGTAATTAAAGAATATTTTGCACAATATTATCATGTTGTTTTAGGCCGTCTGGCTTTGATCCCAATTTTGAT
TATCGCGCTTACCGGAACTTATTTATCGCTGGAAAGATTTAACTTTTTTATGGGTGAAGAAAAAGCAAAACCGGTAAAAA
CAGAACTTTCGGCGGAAGCCAAAAAAACTTCGGTATTTAAAACCACACTCCTGTCTGAAGTAAAGAAAATCGAATTTCCT
TTTACAGATGATCCTGAAGAATATTATATCATTGAACTAAAAGACCGCGAAATTGAAGTCAATCAGGTTGACGGCACTTT
ACTTTCAGAAAAACGTTCGCCGTTTACTGTTCAGTTATCAGCTTTAAGCCTTGACCTGCATACAGGAAGAATTAATACTG
TCTGGGCTGTAATTTTAGCCATTGCGTGTCTCAATATTCTTTTCTTTATTTATTCTGGTTTTGCTATTACTCTAAAACGA
AGATCAAGCCGAATTAAAAATAAATTCAAAGCCAATGAAAGCAATTATATTTTGCTGGTTGGTTCTGAAAACGGAAGCTC
TTTTCGATTTGCCAATGCTATTGCGAAGCAGTTAATCAGCCATGGAAAAAAAGTTTTTACGGCCGAATTAAATAGTTTTT
CGGTTTACCCAAAAGCTGAGCATATTATTGTTTTTTCGTCTACTCATGGTTTAGGTGATCCGCCTTCAAACGCCAGAAAA
TTCAAAACCCTTTTACAAAAACAAAATCAGGAACAAAAAATTAAATTTTCGGTTGTTGGTTTTGGATCAAAATCTTATCC
TGATTTCTGTCAATTTGCTATTGAAATCGATCAGCTTCTGGAAAATCAAAATTGGGCAGAACGCTTTTTAGATTTACAAA
CCGTTAATGATAAATCGGCAGTTGAGTTTACAGAATGGTTGAAATTATGGAGCGGGAAAACCGAAATTCCACTTGCCTGT
ACTCCATCTCTGTACAACCATGTTCCAAAAGGTTTACAAAAATTAATGGTTTTAGATAAAACGCCAATTTCAGATACTGA
ACATACATTTATTTTAACACTGCACGCCAATAGCCGAACGAAATTTGCTTCGGGCGATTTACTGGCTGTTTATCCTGCCA
ATGATTCGAGAGAACGCCTCTACTCTATTGGAAATCATTCCGGAAATGTACAATTGGTTGTAAAACTGCATCAAAATGGA
TTAGGTTCTGGATATTTAAATAATCTGGAACCGGGCGATACTATTAAAGCCAGAATTATTAATAATCACGCTTTCCATTT
TCCAAAGAAAGCGTCAAAAGTGGCTTTTATTTCTAACGGAACGGGAATTGCTCCTTTTCTTGGAATGATCGAACAAAATA
AAGCTAAGAAAGAAATACAGCTTTACAGCGGATTTAGAATGGAAACGCCGACACTGCTGGCTTATAAAAAGTTTGCCAAT
ATAATGATCCAAAAAGAATATCTGGATAATTTTCATGTCGCTTTATCACGAGAAGCCGAACAAATTTATGTAATGGATTT
GATAAAAAGGGACACAGTCTTTTTTGTTAATTTATTGAAAGACGGCGGTGTAATCATGATTTGCGGTTCACTTGCAATGC
AGAAAGATGTCGAAGTGATTCTGGATGAATTGTGTCGTGATAACGGAATGCAAAATCTCGCTGATTACAAGGAAAAAGGA
CAAATTTTAACCGATTGTTATTAG

Upstream 100 bases:

>100_bases
ATGAAATATTTTTCTGCTTAAACTTAAAATCCGAGCTTTGTCAAAGTTGCAAAACCTTGACAAAGCTTTAAATATTTATT
ACATTTCTAGAATACACTAA

Downstream 100 bases:

>100_bases
GAGTGCAATTTTAGATTGTTGATTTTAGATTGTTGATTATTGATATTACAAATAGATACTACCAATCACAGAGGGATGAC
ATATAGATTAATTGGCAGAT

Product: flavodoxin/nitric oxide synthase

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MTLSFWRYAHLALALFSSIFLLLASVTGIILAVDAVQEKTLPYKAADFDKITLGETLPVLKKEYSEITELSVDYNQFVTL
QAIDKDGNDVNAYIDPKTGKALGTPAKKSEFIKWVTSFHRSLFLHETGRFFVGVISFCLLLISISGFVLVLKRQRGIRNF
FSKVIKEYFAQYYHVVLGRLALIPILIIALTGTYLSLERFNFFMGEEKAKPVKTELSAEAKKTSVFKTTLLSEVKKIEFP
FTDDPEEYYIIELKDREIEVNQVDGTLLSEKRSPFTVQLSALSLDLHTGRINTVWAVILAIACLNILFFIYSGFAITLKR
RSSRIKNKFKANESNYILLVGSENGSSFRFANAIAKQLISHGKKVFTAELNSFSVYPKAEHIIVFSSTHGLGDPPSNARK
FKTLLQKQNQEQKIKFSVVGFGSKSYPDFCQFAIEIDQLLENQNWAERFLDLQTVNDKSAVEFTEWLKLWSGKTEIPLAC
TPSLYNHVPKGLQKLMVLDKTPISDTEHTFILTLHANSRTKFASGDLLAVYPANDSRERLYSIGNHSGNVQLVVKLHQNG
LGSGYLNNLEPGDTIKARIINNHAFHFPKKASKVAFISNGTGIAPFLGMIEQNKAKKEIQLYSGFRMETPTLLAYKKFAN
IMIQKEYLDNFHVALSREAEQIYVMDLIKRDTVFFVNLLKDGGVIMICGSLAMQKDVEVILDELCRDNGMQNLADYKEKG
QILTDCY

Sequences:

>Translated_727_residues
MTLSFWRYAHLALALFSSIFLLLASVTGIILAVDAVQEKTLPYKAADFDKITLGETLPVLKKEYSEITELSVDYNQFVTL
QAIDKDGNDVNAYIDPKTGKALGTPAKKSEFIKWVTSFHRSLFLHETGRFFVGVISFCLLLISISGFVLVLKRQRGIRNF
FSKVIKEYFAQYYHVVLGRLALIPILIIALTGTYLSLERFNFFMGEEKAKPVKTELSAEAKKTSVFKTTLLSEVKKIEFP
FTDDPEEYYIIELKDREIEVNQVDGTLLSEKRSPFTVQLSALSLDLHTGRINTVWAVILAIACLNILFFIYSGFAITLKR
RSSRIKNKFKANESNYILLVGSENGSSFRFANAIAKQLISHGKKVFTAELNSFSVYPKAEHIIVFSSTHGLGDPPSNARK
FKTLLQKQNQEQKIKFSVVGFGSKSYPDFCQFAIEIDQLLENQNWAERFLDLQTVNDKSAVEFTEWLKLWSGKTEIPLAC
TPSLYNHVPKGLQKLMVLDKTPISDTEHTFILTLHANSRTKFASGDLLAVYPANDSRERLYSIGNHSGNVQLVVKLHQNG
LGSGYLNNLEPGDTIKARIINNHAFHFPKKASKVAFISNGTGIAPFLGMIEQNKAKKEIQLYSGFRMETPTLLAYKKFAN
IMIQKEYLDNFHVALSREAEQIYVMDLIKRDTVFFVNLLKDGGVIMICGSLAMQKDVEVILDELCRDNGMQNLADYKEKG
QILTDCY
>Mature_726_residues
TLSFWRYAHLALALFSSIFLLLASVTGIILAVDAVQEKTLPYKAADFDKITLGETLPVLKKEYSEITELSVDYNQFVTLQ
AIDKDGNDVNAYIDPKTGKALGTPAKKSEFIKWVTSFHRSLFLHETGRFFVGVISFCLLLISISGFVLVLKRQRGIRNFF
SKVIKEYFAQYYHVVLGRLALIPILIIALTGTYLSLERFNFFMGEEKAKPVKTELSAEAKKTSVFKTTLLSEVKKIEFPF
TDDPEEYYIIELKDREIEVNQVDGTLLSEKRSPFTVQLSALSLDLHTGRINTVWAVILAIACLNILFFIYSGFAITLKRR
SSRIKNKFKANESNYILLVGSENGSSFRFANAIAKQLISHGKKVFTAELNSFSVYPKAEHIIVFSSTHGLGDPPSNARKF
KTLLQKQNQEQKIKFSVVGFGSKSYPDFCQFAIEIDQLLENQNWAERFLDLQTVNDKSAVEFTEWLKLWSGKTEIPLACT
PSLYNHVPKGLQKLMVLDKTPISDTEHTFILTLHANSRTKFASGDLLAVYPANDSRERLYSIGNHSGNVQLVVKLHQNGL
GSGYLNNLEPGDTIKARIINNHAFHFPKKASKVAFISNGTGIAPFLGMIEQNKAKKEIQLYSGFRMETPTLLAYKKFANI
MIQKEYLDNFHVALSREAEQIYVMDLIKRDTVFFVNLLKDGGVIMICGSLAMQKDVEVILDELCRDNGMQNLADYKEKGQ
ILTDCY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=270, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 82131; Mature: 82000

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSFWRYAHLALALFSSIFLLLASVTGIILAVDAVQEKTLPYKAADFDKITLGETLPVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHH
KKEYSEITELSVDYNQFVTLQAIDKDGNDVNAYIDPKTGKALGTPAKKSEFIKWVTSFHR
HHHHHHHHHEECCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
SLFLHETGRFFVGVISFCLLLISISGFVLVLKRQRGIRNFFSKVIKEYFAQYYHVVLGRL
HEEHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIPILIIALTGTYLSLERFNFFMGEEKAKPVKTELSAEAKKTSVFKTTLLSEVKKIEFP
HHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTDDPEEYYIIELKDREIEVNQVDGTLLSEKRSPFTVQLSALSLDLHTGRINTVWAVILA
CCCCCCCEEEEEEECCEEEEEECCCHHHHCCCCCEEEEEEEEEEEEECCCHHHHHHHHHH
IACLNILFFIYSGFAITLKRRSSRIKNKFKANESNYILLVGSENGSSFRFANAIAKQLIS
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
HGKKVFTAELNSFSVYPKAEHIIVFSSTHGLGDPPSNARKFKTLLQKQNQEQKIKFSVVG
CCCEEEEEECCCEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
FGSKSYPDFCQFAIEIDQLLENQNWAERFLDLQTVNDKSAVEFTEWLKLWSGKTEIPLAC
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCEEE
TPSLYNHVPKGLQKLMVLDKTPISDTEHTFILTLHANSRTKFASGDLLAVYPANDSRERL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEECCCCEEEEECCCCCHHHH
YSIGNHSGNVQLVVKLHQNGLGSGYLNNLEPGDTIKARIINNHAFHFPKKASKVAFISNG
HHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECC
TGIAPFLGMIEQNKAKKEIQLYSGFRMETPTLLAYKKFANIMIQKEYLDNFHVALSREAE
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEHHHHCCHHEEECCCCH
QIYVMDLIKRDTVFFVNLLKDGGVIMICGSLAMQKDVEVILDELCRDNGMQNLADYKEKG
HHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
QILTDCY
CEECCCC
>Mature Secondary Structure 
TLSFWRYAHLALALFSSIFLLLASVTGIILAVDAVQEKTLPYKAADFDKITLGETLPVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHH
KKEYSEITELSVDYNQFVTLQAIDKDGNDVNAYIDPKTGKALGTPAKKSEFIKWVTSFHR
HHHHHHHHHEECCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
SLFLHETGRFFVGVISFCLLLISISGFVLVLKRQRGIRNFFSKVIKEYFAQYYHVVLGRL
HEEHHHCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIPILIIALTGTYLSLERFNFFMGEEKAKPVKTELSAEAKKTSVFKTTLLSEVKKIEFP
HHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FTDDPEEYYIIELKDREIEVNQVDGTLLSEKRSPFTVQLSALSLDLHTGRINTVWAVILA
CCCCCCCEEEEEEECCEEEEEECCCHHHHCCCCCEEEEEEEEEEEEECCCHHHHHHHHHH
IACLNILFFIYSGFAITLKRRSSRIKNKFKANESNYILLVGSENGSSFRFANAIAKQLIS
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
HGKKVFTAELNSFSVYPKAEHIIVFSSTHGLGDPPSNARKFKTLLQKQNQEQKIKFSVVG
CCCEEEEEECCCEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
FGSKSYPDFCQFAIEIDQLLENQNWAERFLDLQTVNDKSAVEFTEWLKLWSGKTEIPLAC
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCEEE
TPSLYNHVPKGLQKLMVLDKTPISDTEHTFILTLHANSRTKFASGDLLAVYPANDSRERL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEECCCCEEEEECCCCCHHHH
YSIGNHSGNVQLVVKLHQNGLGSGYLNNLEPGDTIKARIINNHAFHFPKKASKVAFISNG
HHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECC
TGIAPFLGMIEQNKAKKEIQLYSGFRMETPTLLAYKKFANIMIQKEYLDNFHVALSREAE
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEHHHHCCHHEEECCCCH
QIYVMDLIKRDTVFFVNLLKDGGVIMICGSLAMQKDVEVILDELCRDNGMQNLADYKEKG
HHHHHHHHHCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
QILTDCY
CEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA