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The map label for this gene is btuB [H]

Identifier: 146301807

GI number: 146301807

Start: 4860376

End: 4862754

Strand: Direct

Name: btuB [H]

Synonym: Fjoh_4071

Alternate gene names: 146301807

Gene position: 4860376-4862754 (Clockwise)

Preceding gene: 146301806

Following gene: 146301808

Centisome position: 79.72

GC content: 33.71

Gene sequence:

>2379_bases
ATGATAACTCTTTCTGGCTGGTCTCAAACTGGAAAAATTACAGGAAAAGTAACCTTTACCAATAACGAAATTGCCACAGG
AGCTTCTGTACAAATCAGCGGTACAAAAAAAAATGCCGTTGTTGATAACAATGGTCAATTTGAATTTAGAAACCTTTCTT
ACGGAAATTATACATTGGATATTTCTTCAATGGAAGCCCAAAACAAAAGTGTAAATATTGTTTTAAATCGTCCTTCGCAA
CAAATTACGATTTCTCTGGAAAAAATAACGGATCCAAAAGCTTTGAACGAAGTATTGATTCAGAAAAAAACTGCCAAAAA
AGAAATCATCGAAAAAGGCTTTTCTGTAAATGTTATCGAAACTCAGGAAGCAGCCAAAAGAAATATCCAAACTAATGATT
TATTAGGACAGTCTGCGGGAGTCAGAATCAGACAAAACGGAGGTTTAGGTTCCAGCGTAAATTACAACCTAAACGGAATG
TCTGGCAATGCCATCCGAATATTTATCGACGGAATTCCTATTTCTACTTACGGTTCGTCTTTTAACTTAAACAGTATTCC
TCCTGCTTTAATTGAAAGAATTGAAGTTTATAAAGGCGTAATTCCAGCACATTTAGCCGATGATGCTTTGGGCGGTGCTA
TTAATGTAATCCTGAAAAAAGGAGCTAAAAATTCGTTGAACGCTTCTGTATCTTATGGTTCATTTAATACCATTCAATCA
AATTTTAATACGACATACCGCGACAAATCTGGTTTTACTTTAAAAGGATCAGGATTTTATAATTACTCTGACAATAATTA
TGAAATATGGGGGAAATTTGCCCGTGACGTACAGGCAGATGGTGTAATGAAACAAATTCGCGCTAAACGTTTTAATGATG
CTTATCGTTCTTATGGAGGCCGTTTTGAACTTGGTTTTACAGATGTTGAGTGGGCTGATACTTTTTTAGTGGGCATAAAC
ATGTCTGATGATTATAATGAAATCCAGCATGGTCAGGCAATGTCTACTCCATATAAAGGAAGGTTTACAGAAGCAGATGC
CAAAGTAATAAGCATTAATTACGCTAAAAAAGATTTTATAATAAAAGGTCTTGAATTTAATATTAATTCGGTTTTCAGCC
AGAGAAATGAGGTTTTAAACGATACAGTAAAATGGAATTACAACTGGTTTAACGAAAAAGCAATTGGTCTTAAAGGTCTT
CCTATTCTAACACCAAACGGAGCACAGCAGGGAGCACCGACAATTCTTCATCTTAATAATAAAATTTTCAGTACAAGGGG
CGGTTTAAATTATTCTGTAAATGAAAATCACAGATTTGTATTCAGTACAATGCTTTACTCATTTATGAGAGATGATTACG
ATGAAATGAAATCTGAACTGGAAAGAAATTTTCAGCAGAAACGCGACCTGCAAAAAAACATTTTATCATTTGCCTACGAA
TTTGAAGGTCTTGGTTCCCGCTTAAGAACAAATGTATTTGGTAAAAGATACAACCAAAAAACGGAACAGAAAACTCCTGT
TTTGACTACAACAAACGGACAGACTAAAATTACCGAAAATCTGGAAAATAACAATACGACTTTCTACGGATACGGATTTG
CAGCATCTTATTTTGTTCTGCCTAAATTAATGTTATCTACATCTGCAGAAAAGGCAATAAGACTTCCGTCTGAAAATGAA
ATTTTTGGTAATCCGGGTGAAAATCAAACATCAAATAGTTCATTAAAACCAGAGCAGAGTAATAACCTAAATGTTGGTCT
TCGATTTGGTCCTTTTAAAATTAATGAACACAAATTCAGTTTTTCGGGTTCAGGATTCTGGAGAAATTCTAAAGATAAAA
TTGTGCGCCAGTTCAGCACCAGAGTTAATGAGGCTCTGCAGGCAACGCCATCTGTAAATATGGGAACTGCACAATCTCTT
GGCTATGAAGCTTCATTAGAATATTCAAATAAAAACAAATTGTTTGTATCAATGAATATGTCACGATTTAATTCATTGTT
CAAACTTAAATACGATCCAAACGGCAAAATTTATGACAATTATAATAAACAGTATCCAAATGAACCTTACTTCATTATAA
ATACTAATGCACAATACAACTTTAAAAATGTATTACAGGAAAAATCAGAATTGAATCTATATTACAATTTTAGTTATGTA
GGTGAATTTTATACAACATGGCTTCAAACAGAAATGGACAAAACTCCATCGCAGTTTCCTCATGATCTGGGTTTAAGTTA
CATATTTCCAGGCAAAAGATATATTGTAAGCTTTGATGCTAAAAACATAACCAACGAAGAGGTTTATGACAATTTTGCGG
TTCAAAAACCCGGAAGAGCTTTCTATTTAAAAGTAAACTACATACTCAATAAATTTTAG

Upstream 100 bases:

>100_bases
AACAGGTTTATTTAGATCAAATTTAAATAATACTATAAGTTTGCTGCCATATAAAATCAGTACAACTTAAAATATGAGAT
TTTTTTACTTTCTCCTTTTC

Downstream 100 bases:

>100_bases
TAACTAATTAATAACTTTTAATGTAATAAATATGAAAAAAAGTACATTTAAACTACTGGCATGTGGATTGGTTTTTACCA
CATTTGCGCTGACAAGCTGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MITLSGWSQTGKITGKVTFTNNEIATGASVQISGTKKNAVVDNNGQFEFRNLSYGNYTLDISSMEAQNKSVNIVLNRPSQ
QITISLEKITDPKALNEVLIQKKTAKKEIIEKGFSVNVIETQEAAKRNIQTNDLLGQSAGVRIRQNGGLGSSVNYNLNGM
SGNAIRIFIDGIPISTYGSSFNLNSIPPALIERIEVYKGVIPAHLADDALGGAINVILKKGAKNSLNASVSYGSFNTIQS
NFNTTYRDKSGFTLKGSGFYNYSDNNYEIWGKFARDVQADGVMKQIRAKRFNDAYRSYGGRFELGFTDVEWADTFLVGIN
MSDDYNEIQHGQAMSTPYKGRFTEADAKVISINYAKKDFIIKGLEFNINSVFSQRNEVLNDTVKWNYNWFNEKAIGLKGL
PILTPNGAQQGAPTILHLNNKIFSTRGGLNYSVNENHRFVFSTMLYSFMRDDYDEMKSELERNFQQKRDLQKNILSFAYE
FEGLGSRLRTNVFGKRYNQKTEQKTPVLTTTNGQTKITENLENNNTTFYGYGFAASYFVLPKLMLSTSAEKAIRLPSENE
IFGNPGENQTSNSSLKPEQSNNLNVGLRFGPFKINEHKFSFSGSGFWRNSKDKIVRQFSTRVNEALQATPSVNMGTAQSL
GYEASLEYSNKNKLFVSMNMSRFNSLFKLKYDPNGKIYDNYNKQYPNEPYFIINTNAQYNFKNVLQEKSELNLYYNFSYV
GEFYTTWLQTEMDKTPSQFPHDLGLSYIFPGKRYIVSFDAKNITNEEVYDNFAVQKPGRAFYLKVNYILNKF

Sequences:

>Translated_792_residues
MITLSGWSQTGKITGKVTFTNNEIATGASVQISGTKKNAVVDNNGQFEFRNLSYGNYTLDISSMEAQNKSVNIVLNRPSQ
QITISLEKITDPKALNEVLIQKKTAKKEIIEKGFSVNVIETQEAAKRNIQTNDLLGQSAGVRIRQNGGLGSSVNYNLNGM
SGNAIRIFIDGIPISTYGSSFNLNSIPPALIERIEVYKGVIPAHLADDALGGAINVILKKGAKNSLNASVSYGSFNTIQS
NFNTTYRDKSGFTLKGSGFYNYSDNNYEIWGKFARDVQADGVMKQIRAKRFNDAYRSYGGRFELGFTDVEWADTFLVGIN
MSDDYNEIQHGQAMSTPYKGRFTEADAKVISINYAKKDFIIKGLEFNINSVFSQRNEVLNDTVKWNYNWFNEKAIGLKGL
PILTPNGAQQGAPTILHLNNKIFSTRGGLNYSVNENHRFVFSTMLYSFMRDDYDEMKSELERNFQQKRDLQKNILSFAYE
FEGLGSRLRTNVFGKRYNQKTEQKTPVLTTTNGQTKITENLENNNTTFYGYGFAASYFVLPKLMLSTSAEKAIRLPSENE
IFGNPGENQTSNSSLKPEQSNNLNVGLRFGPFKINEHKFSFSGSGFWRNSKDKIVRQFSTRVNEALQATPSVNMGTAQSL
GYEASLEYSNKNKLFVSMNMSRFNSLFKLKYDPNGKIYDNYNKQYPNEPYFIINTNAQYNFKNVLQEKSELNLYYNFSYV
GEFYTTWLQTEMDKTPSQFPHDLGLSYIFPGKRYIVSFDAKNITNEEVYDNFAVQKPGRAFYLKVNYILNKF
>Mature_792_residues
MITLSGWSQTGKITGKVTFTNNEIATGASVQISGTKKNAVVDNNGQFEFRNLSYGNYTLDISSMEAQNKSVNIVLNRPSQ
QITISLEKITDPKALNEVLIQKKTAKKEIIEKGFSVNVIETQEAAKRNIQTNDLLGQSAGVRIRQNGGLGSSVNYNLNGM
SGNAIRIFIDGIPISTYGSSFNLNSIPPALIERIEVYKGVIPAHLADDALGGAINVILKKGAKNSLNASVSYGSFNTIQS
NFNTTYRDKSGFTLKGSGFYNYSDNNYEIWGKFARDVQADGVMKQIRAKRFNDAYRSYGGRFELGFTDVEWADTFLVGIN
MSDDYNEIQHGQAMSTPYKGRFTEADAKVISINYAKKDFIIKGLEFNINSVFSQRNEVLNDTVKWNYNWFNEKAIGLKGL
PILTPNGAQQGAPTILHLNNKIFSTRGGLNYSVNENHRFVFSTMLYSFMRDDYDEMKSELERNFQQKRDLQKNILSFAYE
FEGLGSRLRTNVFGKRYNQKTEQKTPVLTTTNGQTKITENLENNNTTFYGYGFAASYFVLPKLMLSTSAEKAIRLPSENE
IFGNPGENQTSNSSLKPEQSNNLNVGLRFGPFKINEHKFSFSGSGFWRNSKDKIVRQFSTRVNEALQATPSVNMGTAQSL
GYEASLEYSNKNKLFVSMNMSRFNSLFKLKYDPNGKIYDNYNKQYPNEPYFIINTNAQYNFKNVLQEKSELNLYYNFSYV
GEFYTTWLQTEMDKTPSQFPHDLGLSYIFPGKRYIVSFDAKNITNEEVYDNFAVQKPGRAFYLKVNYILNKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 89651; Mature: 89651

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLSGWSQTGKITGKVTFTNNEIATGASVQISGTKKNAVVDNNGQFEFRNLSYGNYTLD
CEEECCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEECCCCCEEEEEECCCCEEEE
ISSMEAQNKSVNIVLNRPSQQITISLEKITDPKALNEVLIQKKTAKKEIIEKGFSVNVIE
EECCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
TQEAAKRNIQTNDLLGQSAGVRIRQNGGLGSSVNYNLNGMSGNAIRIFIDGIPISTYGSS
CHHHHHCCCCHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEECEEEEECCCC
FNLNSIPPALIERIEVYKGVIPAHLADDALGGAINVILKKGAKNSLNASVSYGSFNTIQS
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCHHHHC
NFNTTYRDKSGFTLKGSGFYNYSDNNYEIWGKFARDVQADGVMKQIRAKRFNDAYRSYGG
CCCCEEECCCCCEEECCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RFELGFTDVEWADTFLVGINMSDDYNEIQHGQAMSTPYKGRFTEADAKVISINYAKKDFI
EEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCEECCCCEEEEEEECCCCEE
IKGLEFNINSVFSQRNEVLNDTVKWNYNWFNEKAIGLKGLPILTPNGAQQGAPTILHLNN
EEEEEECHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECC
KIFSTRGGLNYSVNENHRFVFSTMLYSFMRDDYDEMKSELERNFQQKRDLQKNILSFAYE
EEEECCCCEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEGLGSRLRTNVFGKRYNQKTEQKTPVLTTTNGQTKITENLENNNTTFYGYGFAASYFVL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEECHHHHHHHH
PKLMLSTSAEKAIRLPSENEIFGNPGENQTSNSSLKPEQSNNLNVGLRFGPFKINEHKFS
HHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEECCEEEE
FSGSGFWRNSKDKIVRQFSTRVNEALQATPSVNMGTAQSLGYEASLEYSNKNKLFVSMNM
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCEEEEEECH
SRFNSLFKLKYDPNGKIYDNYNKQYPNEPYFIINTNAQYNFKNVLQEKSELNLYYNFSYV
HHCCCEEEEEECCCCCEECCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEEEEEEEH
GEFYTTWLQTEMDKTPSQFPHDLGLSYIFPGKRYIVSFDAKNITNEEVYDNFAVQKPGRA
HHHHHHHHHHHHCCCCCCCCHHCCCEEEECCCEEEEEECCCCCCCHHHHCCCCCCCCCCE
FYLKVNYILNKF
EEEEEEEEECCC
>Mature Secondary Structure
MITLSGWSQTGKITGKVTFTNNEIATGASVQISGTKKNAVVDNNGQFEFRNLSYGNYTLD
CEEECCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEECCCCCEEEEEECCCCEEEE
ISSMEAQNKSVNIVLNRPSQQITISLEKITDPKALNEVLIQKKTAKKEIIEKGFSVNVIE
EECCCCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
TQEAAKRNIQTNDLLGQSAGVRIRQNGGLGSSVNYNLNGMSGNAIRIFIDGIPISTYGSS
CHHHHHCCCCHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEEECEEEEECCCC
FNLNSIPPALIERIEVYKGVIPAHLADDALGGAINVILKKGAKNSLNASVSYGSFNTIQS
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCHHHHC
NFNTTYRDKSGFTLKGSGFYNYSDNNYEIWGKFARDVQADGVMKQIRAKRFNDAYRSYGG
CCCCEEECCCCCEEECCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RFELGFTDVEWADTFLVGINMSDDYNEIQHGQAMSTPYKGRFTEADAKVISINYAKKDFI
EEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCEECCCCEEEEEEECCCCEE
IKGLEFNINSVFSQRNEVLNDTVKWNYNWFNEKAIGLKGLPILTPNGAQQGAPTILHLNN
EEEEEECHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEECC
KIFSTRGGLNYSVNENHRFVFSTMLYSFMRDDYDEMKSELERNFQQKRDLQKNILSFAYE
EEEECCCCEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEGLGSRLRTNVFGKRYNQKTEQKTPVLTTTNGQTKITENLENNNTTFYGYGFAASYFVL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCEEEEEECHHHHHHHH
PKLMLSTSAEKAIRLPSENEIFGNPGENQTSNSSLKPEQSNNLNVGLRFGPFKINEHKFS
HHHHHHCCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEECCEEEE
FSGSGFWRNSKDKIVRQFSTRVNEALQATPSVNMGTAQSLGYEASLEYSNKNKLFVSMNM
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCEEEEEECH
SRFNSLFKLKYDPNGKIYDNYNKQYPNEPYFIINTNAQYNFKNVLQEKSELNLYYNFSYV
HHCCCEEEEEECCCCCEECCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEEEEEEEH
GEFYTTWLQTEMDKTPSQFPHDLGLSYIFPGKRYIVSFDAKNITNEEVYDNFAVQKPGRA
HHHHHHHHHHHHCCCCCCCCHHCCCEEEECCCEEEEEECCCCCCCHHHHCCCCCCCCCCE
FYLKVNYILNKF
EEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA