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The map label for this gene is prmA [H]

Identifier: 146301249

GI number: 146301249

Start: 4182800

End: 4183681

Strand: Direct

Name: prmA [H]

Synonym: Fjoh_3507

Alternate gene names: 146301249

Gene position: 4182800-4183681 (Clockwise)

Preceding gene: 146301246

Following gene: 146301250

Centisome position: 68.61

GC content: 33.33

Gene sequence:

>882_bases
ATGAACAACTTTTGCTTTGTATTCTTACCTTTGCAAAAATTTTTATTTATGTCGAATATATATTTAGGATATCATTTTAC
AATTGAGCCAAAAGAATTGGGTTCTGAAATTTTAGTGGCTGAATTGGGCGAAAAAGCGTTTGAAAGTTTTACAGAAACTG
AAAACGGAATTTCGGCTTTTGTGAAAAAGGATTTATGGGATGAAAATATTCTGGATGATATTTATATTCTACAATCTGAG
GAGTTTAAAATTGAATATACAATTGAAGAAATCGATCAGGTAAACTGGAACGAGGAATGGGAAAAGAATTTCGAGCCAAT
TGATGTTGATGGTAAATGTCATGTACGCGCTCCTTTTCACGAAAAAACGGATGCTGAATTTGACATTGTTATTGAACCTA
AAATGAGTTTTGGAACCGGACATCACGAAACCACTCACATGATGATTCAGCATTTACTGGAAATGGATGTTAAAGGTTTA
AAAACACTTGACATGGGATGCGGAACTGCAATTTTAGCCATTTTAGCTGAAATGAAAGGCGCTGAACCAATCGATGCAAT
TGATATTGACAATTGGTGTTATTTAAATTCTATTGAAAATGCCGAACGCAATAATTGTAAACATATCTCCGTTTATGAGG
GCGATGCGGCTTTATTGGCAGGAAAAAAATACGATTTGATTATTGCCAATATCAACCGAAACATTTTGTTAAATGATATG
CAGGCTTACGTTGATAGTTTAAATCCAAAGGGAATTATTTTATTCAGCGGTTTTTATGAAGAAGACATTCCGTTTATCGA
TGCTTCATGCACAGAAAAAGGTTTGACGTATGTTAAAAAGTTACAAAGAAACAACTGGGTTTCATTAAAATACGTAAATT
AG

Upstream 100 bases:

>100_bases
GACAAAAAGCAGAACAAAAAAAGCATTTTTCATGATAATAAAAAACTTACAAAATATAGTTCAAAATTAGTATTAAAATT
TATAACAATATGATTTATTT

Downstream 100 bases:

>100_bases
ATAGTAATTACAAAGTACAAAAACTAGATAAGATGAGTACTAAAGAGAAAGTAAGAGAAAAAGTCCGCGAGAAAGAAGCG
GCTGTGTTCAATAATGAAAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNNFCFVFLPLQKFLFMSNIYLGYHFTIEPKELGSEILVAELGEKAFESFTETENGISAFVKKDLWDENILDDIYILQSE
EFKIEYTIEEIDQVNWNEEWEKNFEPIDVDGKCHVRAPFHEKTDAEFDIVIEPKMSFGTGHHETTHMMIQHLLEMDVKGL
KTLDMGCGTAILAILAEMKGAEPIDAIDIDNWCYLNSIENAERNNCKHISVYEGDAALLAGKKYDLIIANINRNILLNDM
QAYVDSLNPKGIILFSGFYEEDIPFIDASCTEKGLTYVKKLQRNNWVSLKYVN

Sequences:

>Translated_293_residues
MNNFCFVFLPLQKFLFMSNIYLGYHFTIEPKELGSEILVAELGEKAFESFTETENGISAFVKKDLWDENILDDIYILQSE
EFKIEYTIEEIDQVNWNEEWEKNFEPIDVDGKCHVRAPFHEKTDAEFDIVIEPKMSFGTGHHETTHMMIQHLLEMDVKGL
KTLDMGCGTAILAILAEMKGAEPIDAIDIDNWCYLNSIENAERNNCKHISVYEGDAALLAGKKYDLIIANINRNILLNDM
QAYVDSLNPKGIILFSGFYEEDIPFIDASCTEKGLTYVKKLQRNNWVSLKYVN
>Mature_293_residues
MNNFCFVFLPLQKFLFMSNIYLGYHFTIEPKELGSEILVAELGEKAFESFTETENGISAFVKKDLWDENILDDIYILQSE
EFKIEYTIEEIDQVNWNEEWEKNFEPIDVDGKCHVRAPFHEKTDAEFDIVIEPKMSFGTGHHETTHMMIQHLLEMDVKGL
KTLDMGCGTAILAILAEMKGAEPIDAIDIDNWCYLNSIENAERNNCKHISVYEGDAALLAGKKYDLIIANINRNILLNDM
QAYVDSLNPKGIILFSGFYEEDIPFIDASCTEKGLTYVKKLQRNNWVSLKYVN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=121, Percent_Identity=34.7107438016529, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33711; Mature: 33711

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFCFVFLPLQKFLFMSNIYLGYHFTIEPKELGSEILVAELGEKAFESFTETENGISAF
CCCEEEEEEHHHHHHHHHCEEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
VKKDLWDENILDDIYILQSEEFKIEYTIEEIDQVNWNEEWEKNFEPIDVDGKCHVRAPFH
HHHHCCCCCCCCCEEEEECCCEEEEEEHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCC
EKTDAEFDIVIEPKMSFGTGHHETTHMMIQHLLEMDVKGLKTLDMGCGTAILAILAEMKG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCC
AEPIDAIDIDNWCYLNSIENAERNNCKHISVYEGDAALLAGKKYDLIIANINRNILLNDM
CCCCCEEECCCEEEECCCCCCCCCCCCEEEEEECCEEEEECCCEEEEEEECCCCEEEHHH
QAYVDSLNPKGIILFSGFYEEDIPFIDASCTEKGLTYVKKLQRNNWVSLKYVN
HHHHHCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MNNFCFVFLPLQKFLFMSNIYLGYHFTIEPKELGSEILVAELGEKAFESFTETENGISAF
CCCEEEEEEHHHHHHHHHCEEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
VKKDLWDENILDDIYILQSEEFKIEYTIEEIDQVNWNEEWEKNFEPIDVDGKCHVRAPFH
HHHHCCCCCCCCCEEEEECCCEEEEEEHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCC
EKTDAEFDIVIEPKMSFGTGHHETTHMMIQHLLEMDVKGLKTLDMGCGTAILAILAEMKG
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCC
AEPIDAIDIDNWCYLNSIENAERNNCKHISVYEGDAALLAGKKYDLIIANINRNILLNDM
CCCCCEEECCCEEEECCCCCCCCCCCCEEEEEECCEEEEECCCEEEEEEECCCCEEEHHH
QAYVDSLNPKGIILFSGFYEEDIPFIDASCTEKGLTYVKKLQRNNWVSLKYVN
HHHHHCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA