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The map label for this gene is ykoH [H]

Identifier: 146301141

GI number: 146301141

Start: 4062366

End: 4063769

Strand: Reverse

Name: ykoH [H]

Synonym: Fjoh_3399

Alternate gene names: 146301141

Gene position: 4063769-4062366 (Counterclockwise)

Preceding gene: 146301142

Following gene: 146301140

Centisome position: 66.65

GC content: 33.05

Gene sequence:

>1404_bases
ATGGATATTAGAAAAAAAATTACTTTTACTTATGTAGCACTTTCTACCTTTAGTACCTTGCTATTGAGTATTATAGTATT
CGTTTTATTTAGAGAAAATAACCGTTATCATTTCTTGAAAAGACTGGAAGACCGCGCAAAAATTGTGGCTTCTATCCATT
TTCAGCATGATCCCGAAAAAATCAAATATTACAGCAACTTAAAGAAAAACGGGCTTGAGGAACTTATTGAAGAAGAAGAA
TATGTTCTTAAAATAAACAGTGCCAATAGTTTCGATTATAATACTAAACTAAATCTTCCAAATAAGTTTTATTCTAATAT
CCTTGCAACCGGAGAAGATTATTTTGAAGTCAACAGCAAATATTATCTTGGACAGGTTTTTACAGAAAGAGACCAAAAAT
ATATTGTAATTGTTGGCGCGCGCGACCGCAGAGGAAAAACTACAACCGTTTATATTGTCAAAATATTGCTTTTTGGCGGT
ATTGGTTTTATACTTCTGGCTTTCTTTTTAGGTCGTTTTCTGGCTAAAAGGGTTATAAATCCTGTAGCTAGAATAACAAA
AGAAGTAAACAGAATCAGTGCTTCAAATCTTCATAACCGATTGCCGGCCGTTAAAAACTCTGATGAAATTTCAGATTTAA
CAGAAACCTTCAACGATATGCTTGACAGGCTTGAAACATCATTTGAAATTCAGGCCAATTTTATCAATAATGCTTCACAC
GAATTAAAAACGCCAATTACTACGATTATTGCCGAGGCAGAAATTATGCTTCTAAAAGAACGTGAAGTAGCAGAATATAT
AGAATCATTACAAAACATATACGGACAGGCTTCAAGATTAGGAAACCTCACTGAAAGTTTATTAAAATTGACTCAAACGG
GGTACGATGGAAATAAACAGGTTTTGGACATTGCCAGAATCGATGAATTACTATTGGATGTAAAATCTGATTTAGATAAA
ATTTTCCCGGATAACCGTGTGAGTATTAAAATGAATTTTGCACCAAAAGATTCTAATTTACTTTTAATTCCCTGCAATAA
ACCGCTTTTAGAACTGGCGATTAATAATATTATAACCAACGGCGTTAAATATTCAGACAATAATGAAGTATTTGTAACGC
TTTCGGCAAACCTGGATGCGATTAAAATTTCGATTAATGATATCGGGATCGGAATTCCGCCAGAAGATATTCCGCATTTG
TATGAACCTTTCTTTAGAGGGAAAATTGCGGCAAAATATATAGGTTATGGTTTAGGTCTTCCATTGGCTTCAAAAATCAT
TCGCATGCACGACGGAGAAATACAAGTACAATCAGAACAAAATAAAGGTACGATTGTAACCATCATCTTTAAAAAAACAA
ATCCGAAAAAGAACAACATTAAAAATTCTAATGTTGAATCTTAG

Upstream 100 bases:

>100_bases
GATGTTTATATTACCTATTTAAGAAAAAAAGTAGACAAGCCTTTTAAAACTAAACTAATTCATACCATGAAAGGTTTAGG
TTACGTTATAAAGCCATAAA

Downstream 100 bases:

>100_bases
AAAAATCTAATTTAAGATTAAGACCCTTCTAATTTTCAGGCAGTTATTTTGTATGTATAAACTAAAAGATTATACATATG
AAAAATTTCCTAATACCTAC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MDIRKKITFTYVALSTFSTLLLSIIVFVLFRENNRYHFLKRLEDRAKIVASIHFQHDPEKIKYYSNLKKNGLEELIEEEE
YVLKINSANSFDYNTKLNLPNKFYSNILATGEDYFEVNSKYYLGQVFTERDQKYIVIVGARDRRGKTTTVYIVKILLFGG
IGFILLAFFLGRFLAKRVINPVARITKEVNRISASNLHNRLPAVKNSDEISDLTETFNDMLDRLETSFEIQANFINNASH
ELKTPITTIIAEAEIMLLKEREVAEYIESLQNIYGQASRLGNLTESLLKLTQTGYDGNKQVLDIARIDELLLDVKSDLDK
IFPDNRVSIKMNFAPKDSNLLLIPCNKPLLELAINNIITNGVKYSDNNEVFVTLSANLDAIKISINDIGIGIPPEDIPHL
YEPFFRGKIAAKYIGYGLGLPLASKIIRMHDGEIQVQSEQNKGTIVTIIFKKTNPKKNNIKNSNVES

Sequences:

>Translated_467_residues
MDIRKKITFTYVALSTFSTLLLSIIVFVLFRENNRYHFLKRLEDRAKIVASIHFQHDPEKIKYYSNLKKNGLEELIEEEE
YVLKINSANSFDYNTKLNLPNKFYSNILATGEDYFEVNSKYYLGQVFTERDQKYIVIVGARDRRGKTTTVYIVKILLFGG
IGFILLAFFLGRFLAKRVINPVARITKEVNRISASNLHNRLPAVKNSDEISDLTETFNDMLDRLETSFEIQANFINNASH
ELKTPITTIIAEAEIMLLKEREVAEYIESLQNIYGQASRLGNLTESLLKLTQTGYDGNKQVLDIARIDELLLDVKSDLDK
IFPDNRVSIKMNFAPKDSNLLLIPCNKPLLELAINNIITNGVKYSDNNEVFVTLSANLDAIKISINDIGIGIPPEDIPHL
YEPFFRGKIAAKYIGYGLGLPLASKIIRMHDGEIQVQSEQNKGTIVTIIFKKTNPKKNNIKNSNVES
>Mature_467_residues
MDIRKKITFTYVALSTFSTLLLSIIVFVLFRENNRYHFLKRLEDRAKIVASIHFQHDPEKIKYYSNLKKNGLEELIEEEE
YVLKINSANSFDYNTKLNLPNKFYSNILATGEDYFEVNSKYYLGQVFTERDQKYIVIVGARDRRGKTTTVYIVKILLFGG
IGFILLAFFLGRFLAKRVINPVARITKEVNRISASNLHNRLPAVKNSDEISDLTETFNDMLDRLETSFEIQANFINNASH
ELKTPITTIIAEAEIMLLKEREVAEYIESLQNIYGQASRLGNLTESLLKLTQTGYDGNKQVLDIARIDELLLDVKSDLDK
IFPDNRVSIKMNFAPKDSNLLLIPCNKPLLELAINNIITNGVKYSDNNEVFVTLSANLDAIKISINDIGIGIPPEDIPHL
YEPFFRGKIAAKYIGYGLGLPLASKIIRMHDGEIQVQSEQNKGTIVTIIFKKTNPKKNNIKNSNVES

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=305, Percent_Identity=24.9180327868852, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=25.9259259259259, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790551, Length=356, Percent_Identity=23.5955056179775, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790346, Length=259, Percent_Identity=25.4826254826255, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=24.6621621621622, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=383, Percent_Identity=24.0208877284595, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=26.8085106382979, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=24.1007194244604, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=462, Percent_Identity=21.8614718614719, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=238, Percent_Identity=22.2689075630252, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=26.271186440678, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=275, Percent_Identity=26.1818181818182, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=25.1101321585903, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=22.7564102564103, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=25.4545454545455, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=28.0155642023346, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53219; Mature: 53219

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRKKITFTYVALSTFSTLLLSIIVFVLFRENNRYHFLKRLEDRAKIVASIHFQHDPEK
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCHHH
IKYYSNLKKNGLEELIEEEEYVLKINSANSFDYNTKLNLPNKFYSNILATGEDYFEVNSK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCHHEEECCC
YYLGQVFTERDQKYIVIVGARDRRGKTTTVYIVKILLFGGIGFILLAFFLGRFLAKRVIN
EEEEHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVARITKEVNRISASNLHNRLPAVKNSDEISDLTETFNDMLDRLETSFEIQANFINNASH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCH
ELKTPITTIIAEAEIMLLKEREVAEYIESLQNIYGQASRLGNLTESLLKLTQTGYDGNKQ
HHHCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VLDIARIDELLLDVKSDLDKIFPDNRVSIKMNFAPKDSNLLLIPCNKPLLELAINNIITN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHC
GVKYSDNNEVFVTLSANLDAIKISINDIGIGIPPEDIPHLYEPFFRGKIAAKYIGYGLGL
CEEECCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHCCCH
PLASKIIRMHDGEIQVQSEQNKGTIVTIIFKKTNPKKNNIKNSNVES
HHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDIRKKITFTYVALSTFSTLLLSIIVFVLFRENNRYHFLKRLEDRAKIVASIHFQHDPEK
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCHHH
IKYYSNLKKNGLEELIEEEEYVLKINSANSFDYNTKLNLPNKFYSNILATGEDYFEVNSK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCHHEEECCC
YYLGQVFTERDQKYIVIVGARDRRGKTTTVYIVKILLFGGIGFILLAFFLGRFLAKRVIN
EEEEHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVARITKEVNRISASNLHNRLPAVKNSDEISDLTETFNDMLDRLETSFEIQANFINNASH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCH
ELKTPITTIIAEAEIMLLKEREVAEYIESLQNIYGQASRLGNLTESLLKLTQTGYDGNKQ
HHHCCHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VLDIARIDELLLDVKSDLDKIFPDNRVSIKMNFAPKDSNLLLIPCNKPLLELAINNIITN
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHC
GVKYSDNNEVFVTLSANLDAIKISINDIGIGIPPEDIPHLYEPFFRGKIAAKYIGYGLGL
CEEECCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHCCCH
PLASKIIRMHDGEIQVQSEQNKGTIVTIIFKKTNPKKNNIKNSNVES
HHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]