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The map label for this gene is tcrA [H]

Identifier: 146301142

GI number: 146301142

Start: 4063771

End: 4064445

Strand: Reverse

Name: tcrA [H]

Synonym: Fjoh_3400

Alternate gene names: 146301142

Gene position: 4064445-4063771 (Counterclockwise)

Preceding gene: 146301143

Following gene: 146301141

Centisome position: 66.66

GC content: 34.52

Gene sequence:

>675_bases
ATGAAGTTACTAATAGTCGAAGACGAACCAAATCTTTTATCGATTTTACGTAAAGGTTTTGCCGAAAATAACAACGAAGT
AAGTGTGGCTCTTGATGGTAAAACTGCCCTTGAGATGATTGACAATTATAACTTTGATGTTGTCGTTTTAGATGTTATGC
TGCCGGATATTAACGGAATAGAGATTTGCAGAAGACTTCGCGCCAGTAAAAACTTTGTGCCTATTTTACTTTTAACGGCT
TTAGGAACTTCAGAAAATATTGTAACAGGACTTAATTCCGGTGCCGATGATTATTTGGTAAAGCCTTTTAAATTTGGAGA
ACTTGATGCCCGCGTAAACGCCCTGCACAGAAGAGCACATCAGGAAACCGATAAAATTGACGTGATTACTATTGGCGATT
TAGAAATAAACGGACGTGCTAAAACCGTTAAAAGAGATGGAGAATCTATTATTTTAACAGCAAAAGAGTTTAAACTCCTG
TATTATTTAGGTAAAAATGCCGGAAGAATTGTTTCTCGCGATCAGATTTTAGATAATGTCTGGGACATTAATTTTGACAT
GAATACCAATGTTGTTGATGTTTATATTACCTATTTAAGAAAAAAAGTAGACAAGCCTTTTAAAACTAAACTAATTCATA
CCATGAAAGGTTTAGGTTACGTTATAAAGCCATAA

Upstream 100 bases:

>100_bases
GCTTGTAAAAGTCATTGTTCATAATTAAATCATAATTTATAACTATTATGAATAATATTTTTGAACTCAATCCTTATTTT
TGTTGTATATACAAGTTAAT

Downstream 100 bases:

>100_bases
AATGGATATTAGAAAAAAAATTACTTTTACTTATGTAGCACTTTCTACCTTTAGTACCTTGCTATTGAGTATTATAGTAT
TCGTTTTATTTAGAGAAAAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKLLIVEDEPNLLSILRKGFAENNNEVSVALDGKTALEMIDNYNFDVVVLDVMLPDINGIEICRRLRASKNFVPILLLTA
LGTSENIVTGLNSGADDYLVKPFKFGELDARVNALHRRAHQETDKIDVITIGDLEINGRAKTVKRDGESIILTAKEFKLL
YYLGKNAGRIVSRDQILDNVWDINFDMNTNVVDVYITYLRKKVDKPFKTKLIHTMKGLGYVIKP

Sequences:

>Translated_224_residues
MKLLIVEDEPNLLSILRKGFAENNNEVSVALDGKTALEMIDNYNFDVVVLDVMLPDINGIEICRRLRASKNFVPILLLTA
LGTSENIVTGLNSGADDYLVKPFKFGELDARVNALHRRAHQETDKIDVITIGDLEINGRAKTVKRDGESIILTAKEFKLL
YYLGKNAGRIVSRDQILDNVWDINFDMNTNVVDVYITYLRKKVDKPFKTKLIHTMKGLGYVIKP
>Mature_224_residues
MKLLIVEDEPNLLSILRKGFAENNNEVSVALDGKTALEMIDNYNFDVVVLDVMLPDINGIEICRRLRASKNFVPILLLTA
LGTSENIVTGLNSGADDYLVKPFKFGELDARVNALHRRAHQETDKIDVITIGDLEINGRAKTVKRDGESIILTAKEFKLL
YYLGKNAGRIVSRDQILDNVWDINFDMNTNVVDVYITYLRKKVDKPFKTKLIHTMKGLGYVIKP

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=44.8430493273543, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=41.3636363636364, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=33.1877729257642, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=36.9369369369369, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=37.10407239819, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=32.1266968325792, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=31.981981981982, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=30.9417040358744, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=34.6491228070175, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=30.6666666666667, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.0472103004292, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.8370044052863, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=36.1111111111111, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790437, Length=155, Percent_Identity=28.3870967741935, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=30.5785123966942, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=31.0679611650485, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=30, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=115, Percent_Identity=35.6521739130435, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25295; Mature: 25295

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLIVEDEPNLLSILRKGFAENNNEVSVALDGKTALEMIDNYNFDVVVLDVMLPDINGI
CEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCHH
EICRRLRASKNFVPILLLTALGTSENIVTGLNSGADDYLVKPFKFGELDARVNALHRRAH
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
QETDKIDVITIGDLEINGRAKTVKRDGESIILTAKEFKLLYYLGKNAGRIVSRDQILDNV
CCCCCEEEEEECCEEECCCEEEEECCCCEEEEEHHHEEEEEEECCCCCCEEEHHHHHHHH
WDINFDMNTNVVDVYITYLRKKVDKPFKTKLIHTMKGLGYVIKP
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MKLLIVEDEPNLLSILRKGFAENNNEVSVALDGKTALEMIDNYNFDVVVLDVMLPDINGI
CEEEEEECCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCHH
EICRRLRASKNFVPILLLTALGTSENIVTGLNSGADDYLVKPFKFGELDARVNALHRRAH
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
QETDKIDVITIGDLEINGRAKTVKRDGESIILTAKEFKLLYYLGKNAGRIVSRDQILDNV
CCCCCEEEEEECCEEECCCEEEEECCCCEEEEEHHHEEEEEEECCCCCCEEEHHHHHHHH
WDINFDMNTNVVDVYITYLRKKVDKPFKTKLIHTMKGLGYVIKP
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]