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The map label for this gene is arlR [H]

Identifier: 146300485

GI number: 146300485

Start: 3260357

End: 3261037

Strand: Reverse

Name: arlR [H]

Synonym: Fjoh_2735

Alternate gene names: 146300485

Gene position: 3261037-3260357 (Counterclockwise)

Preceding gene: 146300486

Following gene: 146300484

Centisome position: 53.49

GC content: 30.25

Gene sequence:

>681_bases
ATGAAAATATTACTGCTCGAAGACGATTTTACTTTGTCTAAAGAAATATCGGCTTTTTTTACCACTAAACAATTCGAGTG
TACACCGTATTATGATGGATCTTTACTGCTTAAAAAATACTTTCCGTATGAATATGATTTAATAATTCTGGATATTAATG
TTCCGGGAATAAATGGTATTGAGGTTTGTAAAGGTATTCGTGAAATTGATAAAAAAACGCCAATTATAATGCTGACGGCT
TTTAGTGAAATTGAAGACAAACTGGCTTCCTTTGACAGTGGTGCTGATGATTATCTGGTTAAACCTTTTCATTTTGAAGA
ATTATATGCCCGTATTTCATCATTGCTTAGGAGAAAAGAAATTCCTCAGCAAACAGAAAAAAAGATCATTATAGAAGATT
TAGAAATTCTGGAAGATGAAATGAAAGTTTTACGTTCTGGTGAAGAAATTAAGCTGACTCCAAAAGAGTTTAAACTAATT
CTAATTTTAGCCCATGCAAAAGGAAAAGTTTTGTCTAAGCAATTTATTGCCGAGAAACTTTGGGATTATCATATTGAAAC
CAATCAAAATACGATTGAAGTTTATATAAATTTTCTTAGAAAAAAAATCGATAAAGATCACGAAACAAAACTCATAAAAA
CCAAAATTGGTTACGGATATTATTTAAGTAACGAGGAATGA

Upstream 100 bases:

>100_bases
TTGAGAATAACGAAACATTCTCTTATTTCAAATAAAAGCACTTTCATACTAAATTCGGCTGTTTATAAAATAATAGCCGA
ATTTACTAATTCCTCAAAGA

Downstream 100 bases:

>100_bases
CTTTAAAAAACAGAATATCATTATTAGTAAGTCTTTTGTTTACAATCCTTTTTGGATTGGCATCGACTGTGATATTTGTT
TTATATTCTAATTTTAGAAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILLLEDDFTLSKEISAFFTTKQFECTPYYDGSLLLKKYFPYEYDLIILDINVPGINGIEVCKGIREIDKKTPIIMLTA
FSEIEDKLASFDSGADDYLVKPFHFEELYARISSLLRRKEIPQQTEKKIIIEDLEILEDEMKVLRSGEEIKLTPKEFKLI
LILAHAKGKVLSKQFIAEKLWDYHIETNQNTIEVYINFLRKKIDKDHETKLIKTKIGYGYYLSNEE

Sequences:

>Translated_226_residues
MKILLLEDDFTLSKEISAFFTTKQFECTPYYDGSLLLKKYFPYEYDLIILDINVPGINGIEVCKGIREIDKKTPIIMLTA
FSEIEDKLASFDSGADDYLVKPFHFEELYARISSLLRRKEIPQQTEKKIIIEDLEILEDEMKVLRSGEEIKLTPKEFKLI
LILAHAKGKVLSKQFIAEKLWDYHIETNQNTIEVYINFLRKKIDKDHETKLIKTKIGYGYYLSNEE
>Mature_226_residues
MKILLLEDDFTLSKEISAFFTTKQFECTPYYDGSLLLKKYFPYEYDLIILDINVPGINGIEVCKGIREIDKKTPIIMLTA
FSEIEDKLASFDSGADDYLVKPFHFEELYARISSLLRRKEIPQQTEKKIIIEDLEILEDEMKVLRSGEEIKLTPKEFKLI
LILAHAKGKVLSKQFIAEKLWDYHIETNQNTIEVYINFLRKKIDKDHETKLIKTKIGYGYYLSNEE

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=39.1891891891892, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=35.6828193832599, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.4444444444444, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=32.5892857142857, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=35, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=29.3859649122807, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=29.5964125560538, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.4444444444444, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=28.3261802575107, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.1479820627803, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=30.7017543859649, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=30.8411214953271, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=26.8518518518519, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=25.8620689655172, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26506; Mature: 26506

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLLEDDFTLSKEISAFFTTKQFECTPYYDGSLLLKKYFPYEYDLIILDINVPGINGI
CEEEEEECCCCHHHHHHHHEECCEEEECCCCCCCCHHHHCCCCEEEEEEEEEECCCCCHH
EVCKGIREIDKKTPIIMLTAFSEIEDKLASFDSGADDYLVKPFHFEELYARISSLLRRKE
HHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
IPQQTEKKIIIEDLEILEDEMKVLRSGEEIKLTPKEFKLILILAHAKGKVLSKQFIAEKL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHEEEEEEEECCCCCHHHHHHHHHHH
WDYHIETNQNTIEVYINFLRKKIDKDHETKLIKTKIGYGYYLSNEE
HHEEEECCCCHHHHHHHHHHHHHCCCCHHEEEEEECCCEEEECCCC
>Mature Secondary Structure
MKILLLEDDFTLSKEISAFFTTKQFECTPYYDGSLLLKKYFPYEYDLIILDINVPGINGI
CEEEEEECCCCHHHHHHHHEECCEEEECCCCCCCCHHHHCCCCEEEEEEEEEECCCCCHH
EVCKGIREIDKKTPIIMLTAFSEIEDKLASFDSGADDYLVKPFHFEELYARISSLLRRKE
HHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHC
IPQQTEKKIIIEDLEILEDEMKVLRSGEEIKLTPKEFKLILILAHAKGKVLSKQFIAEKL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHEEEEEEEECCCCCHHHHHHHHHHH
WDYHIETNQNTIEVYINFLRKKIDKDHETKLIKTKIGYGYYLSNEE
HHEEEECCCCHHHHHHHHHHHHHCCCCHHEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA