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The map label for this gene is pyrF

Identifier: 146300077

GI number: 146300077

Start: 2790296

End: 2791117

Strand: Direct

Name: pyrF

Synonym: Fjoh_2322

Alternate gene names: 146300077

Gene position: 2790296-2791117 (Clockwise)

Preceding gene: 146300076

Following gene: 146300078

Centisome position: 45.77

GC content: 35.04

Gene sequence:

>822_bases
ATGACAACACAACAACTACACGAACAAATTCTTCAAAAAAAATCATTTTTATGCGTTGGCTTAGATCCTGATTTAAGCAA
AATTCCAGCTCATTTATTAGAAACCGAAGATCCTATTTTCGAATTTAATAAAGCCATAATCGATGCTACTCACGATTTAA
CTGTTGGCTACAAACCTAATACGGCTTTCTTTGAAGCTTATGGAATCAAAGGATGGATGTCTCTGCAGAAAACGATCAAT
TACATCAACGAAAATTATCCTGATATTTTTACGATTGCCGATGCAAAACGCGGTGATATCGGAAATACTTCAAGCATGTA
TGCAAAAGCTTTTTTTGAAGATTTAAATTTTGACAGTGTAACCGTTGCTCCTTATATGGGAAAAGATTCTGTTGAACCTT
TTCTGGCTTTCGAAAACAAACATACCATTATGCTGGCACTGACTTCTAACGAAGGCGCTTTCGATTTTCAGACTTTAAAT
ACAAACGGAACAGAATTATACAAACAAGTTTTGGAAACGTCTAAAACGTGGAAAAACAGCCAAAATTTAATGTATGTAGT
GGGTGCTACAAAAGCAGAATATTTTGCTGATATAAGAAAAATTGTTCCAGATAGTTTTTTATTAGTTCCGGGAATTGGAG
CACAGGGCGGAAGCTTGTCTGAAGTATGCAAATACGGAATGAATGATAAAATTGGACTTTTAGTAAATTCTGCAAGAGCT
ATTATATACGCTTCAAAAGGAACTGACTTTGCTGAAAAGGCCAGGGAAGAAGCTTTGAAAGTACAGCAGGAAATGGCTGA
GATTATTGATTCTAAGTTTTAA

Upstream 100 bases:

>100_bases
ATATACCCAAAAAGCCATTCTTAATTGAGTGGCTTTTTTTATTTTTGCATACTTTTTAAAAAGAATCATTTCTTTGAAAC
AGAAGTTCTAAAAAACTAAT

Downstream 100 bases:

>100_bases
ATAACTTTATAAATAGATTAACCGCAAAGTTCGCTAAGGTTTTTCGCAAGGTTCGCAAAGAAAAACTTTGCGTTCATCGC
GTAAATCTTTGCGAACTTTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTTQQLHEQILQKKSFLCVGLDPDLSKIPAHLLETEDPIFEFNKAIIDATHDLTVGYKPNTAFFEAYGIKGWMSLQKTIN
YINENYPDIFTIADAKRGDIGNTSSMYAKAFFEDLNFDSVTVAPYMGKDSVEPFLAFENKHTIMLALTSNEGAFDFQTLN
TNGTELYKQVLETSKTWKNSQNLMYVVGATKAEYFADIRKIVPDSFLLVPGIGAQGGSLSEVCKYGMNDKIGLLVNSARA
IIYASKGTDFAEKAREEALKVQQEMAEIIDSKF

Sequences:

>Translated_273_residues
MTTQQLHEQILQKKSFLCVGLDPDLSKIPAHLLETEDPIFEFNKAIIDATHDLTVGYKPNTAFFEAYGIKGWMSLQKTIN
YINENYPDIFTIADAKRGDIGNTSSMYAKAFFEDLNFDSVTVAPYMGKDSVEPFLAFENKHTIMLALTSNEGAFDFQTLN
TNGTELYKQVLETSKTWKNSQNLMYVVGATKAEYFADIRKIVPDSFLLVPGIGAQGGSLSEVCKYGMNDKIGLLVNSARA
IIYASKGTDFAEKAREEALKVQQEMAEIIDSKF
>Mature_272_residues
TTQQLHEQILQKKSFLCVGLDPDLSKIPAHLLETEDPIFEFNKAIIDATHDLTVGYKPNTAFFEAYGIKGWMSLQKTINY
INENYPDIFTIADAKRGDIGNTSSMYAKAFFEDLNFDSVTVAPYMGKDSVEPFLAFENKHTIMLALTSNEGAFDFQTLNT
NGTELYKQVLETSKTWKNSQNLMYVVGATKAEYFADIRKIVPDSFLLVPGIGAQGGSLSEVCKYGMNDKIGLLVNSARAI
IYASKGTDFAEKAREEALKVQQEMAEIIDSKF

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_FLAJ1 (A5FHG4)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194668.1
- ProteinModelPortal:   A5FHG4
- SMR:   A5FHG4
- STRING:   A5FHG4
- GeneID:   5090677
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_2322
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   CLSK823836
- BioCyc:   FJOH376686:FJOH_2322-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 30486; Mature: 30355

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQQLHEQILQKKSFLCVGLDPDLSKIPAHLLETEDPIFEFNKAIIDATHDLTVGYKPN
CCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCC
TAFFEAYGIKGWMSLQKTINYINENYPDIFTIADAKRGDIGNTSSMYAKAFFEDLNFDSV
CCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
TVAPYMGKDSVEPFLAFENKHTIMLALTSNEGAFDFQTLNTNGTELYKQVLETSKTWKNS
EEECCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
QNLMYVVGATKAEYFADIRKIVPDSFLLVPGIGAQGGSLSEVCKYGMNDKIGLLVNSARA
CCEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEEEECCEE
IIYASKGTDFAEKAREEALKVQQEMAEIIDSKF
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTQQLHEQILQKKSFLCVGLDPDLSKIPAHLLETEDPIFEFNKAIIDATHDLTVGYKPN
CHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCC
TAFFEAYGIKGWMSLQKTINYINENYPDIFTIADAKRGDIGNTSSMYAKAFFEDLNFDSV
CCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCE
TVAPYMGKDSVEPFLAFENKHTIMLALTSNEGAFDFQTLNTNGTELYKQVLETSKTWKNS
EEECCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
QNLMYVVGATKAEYFADIRKIVPDSFLLVPGIGAQGGSLSEVCKYGMNDKIGLLVNSARA
CCEEEEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEEEECCEE
IIYASKGTDFAEKAREEALKVQQEMAEIIDSKF
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA