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The map label for this gene is surA [H]

Identifier: 146299709

GI number: 146299709

Start: 2257008

End: 2258435

Strand: Direct

Name: surA [H]

Synonym: Fjoh_1949

Alternate gene names: 146299709

Gene position: 2257008-2258435 (Clockwise)

Preceding gene: 146299706

Following gene: 146299710

Centisome position: 37.02

GC content: 31.51

Gene sequence:

>1428_bases
ATGTTATTAAAAAAATTACAGCTAAAAACAATTGATTACAAGTTAGTCTTAACAATGTGTTTTTTACTTTTTTTCACTTC
AATAGTTTCAGCTCAGGAAATTATTAAGGATGTTGTAGCTGAAAAGCCTGCAGAACCAGTGCATGGTAAACAAAAAATAG
ACGGTATTATCGCTACAGTTGGAGATTATATTGTTTTAGATTCTGATATTGATAAAGGTTATTTAGAGATTTCAAGCCAG
GGAGGTAATATTAAAGATATTACAAGATGCCAGATGCTTGGTAAACTTCTTGAAGATAAATTATATGCGCATCAGGCTAT
TCAGGATAGTATTATTGTGAGTGATGCCGAAGTTAGAGGTATGATGGAAGAACGTTTGAACTATATGATTCAACAAGTTG
GAGACATAAATAAAGTAGTCGAATACTATAAAAAAAGTTCTGTAGAGGAATTTAAAACATATTTTGCTGACATCTTAAAA
GAGCAGAAGTTAGCTTCTGAAATGAGAGATAAAATTGTTAAAGATGTAGAAATAACTCCTGAAGAAGTTCGTAATTTCTT
TAGAAAAATTCCTAAAGACGAATTGCCGACTTTTGGAGCTGAAATGGAAGTAGCGCAAATTGTGGTAGAGCCAAAAGTTT
CTAAGGAAGACAAGCAAAAGGTAATAGATAGATTAAATGCTATTAGAAAAGATGTTTTAGAAGGATCAAGCTTTGCAACA
AAAGCTGTTTTATATTCTCAGGATCCTGGATCTGCACCAAATGGCGGTTACTACAAAATGACACGTAAAACACCTTTTGT
AAAAGAGTTTAAAGATGTTGCATTTAGTTTACAGGAAGGTGAGATTTCTGCACCATTTGAAACTACTTTTGGATATCATA
TTATAATGGTAGATAAAATAAAAGGACAGGAAGTAGAATTACGTCATATATTAATTGCTCCAACCGTTTCTGAAAGCGCT
TTAAAAGAAGCAAAAGAAAGAATTGCAAACATTAGAGCTAAAATTGTAAGCAAAGAATTGACTTTTGCAGACGCTGCAAG
AACAGAATCTGATGAAAAAGAAACCAGAGCAAATGGAGGAACATTAATAAATCCTAATACTCAGGATACTCGTTTTGAAT
TGACTAAAATGGATCCAACTTTATACGGTCAGGTTTCAAATTTAAAAGATGATGAAGTTTCTCAGCCGCTTTTAAACACA
GACGATAAAGGAAAGAAAACGTATAAGTTGATAACTGTAACAAACAGAATCGACGAACATACAGCTGATTATGCTAAAGA
TTATACTAAAATTAAAGAATTAGCATTAAAAGAAAAACAAATCAATGCGATAGCAAAATGGTTTGATACTAAGATTAAAG
ATACTTATATCAAAATTATTGGAGAATACAAAGATTGTACGTTTGCTAACAATTGGTTGAAAAAATAA

Upstream 100 bases:

>100_bases
AATTGACTATTTGGTTTTTTAGAATAACTTTTGAAAGAACAAATAAGGTCTTACTAAATTTTAAAGCACTGATCTTTAAC
ATCCAATTAAATTTAAAATA

Downstream 100 bases:

>100_bases
TTTTTATTAAATAAAGAAAAAGAGTTAGTTTTATGAATTCATTAAACTAACTCTTTTTAATTTTAAATATATTCATAAAT
GTCTGACGTAACAGCAATTC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MLLKKLQLKTIDYKLVLTMCFLLFFTSIVSAQEIIKDVVAEKPAEPVHGKQKIDGIIATVGDYIVLDSDIDKGYLEISSQ
GGNIKDITRCQMLGKLLEDKLYAHQAIQDSIIVSDAEVRGMMEERLNYMIQQVGDINKVVEYYKKSSVEEFKTYFADILK
EQKLASEMRDKIVKDVEITPEEVRNFFRKIPKDELPTFGAEMEVAQIVVEPKVSKEDKQKVIDRLNAIRKDVLEGSSFAT
KAVLYSQDPGSAPNGGYYKMTRKTPFVKEFKDVAFSLQEGEISAPFETTFGYHIIMVDKIKGQEVELRHILIAPTVSESA
LKEAKERIANIRAKIVSKELTFADAARTESDEKETRANGGTLINPNTQDTRFELTKMDPTLYGQVSNLKDDEVSQPLLNT
DDKGKKTYKLITVTNRIDEHTADYAKDYTKIKELALKEKQINAIAKWFDTKIKDTYIKIIGEYKDCTFANNWLKK

Sequences:

>Translated_475_residues
MLLKKLQLKTIDYKLVLTMCFLLFFTSIVSAQEIIKDVVAEKPAEPVHGKQKIDGIIATVGDYIVLDSDIDKGYLEISSQ
GGNIKDITRCQMLGKLLEDKLYAHQAIQDSIIVSDAEVRGMMEERLNYMIQQVGDINKVVEYYKKSSVEEFKTYFADILK
EQKLASEMRDKIVKDVEITPEEVRNFFRKIPKDELPTFGAEMEVAQIVVEPKVSKEDKQKVIDRLNAIRKDVLEGSSFAT
KAVLYSQDPGSAPNGGYYKMTRKTPFVKEFKDVAFSLQEGEISAPFETTFGYHIIMVDKIKGQEVELRHILIAPTVSESA
LKEAKERIANIRAKIVSKELTFADAARTESDEKETRANGGTLINPNTQDTRFELTKMDPTLYGQVSNLKDDEVSQPLLNT
DDKGKKTYKLITVTNRIDEHTADYAKDYTKIKELALKEKQINAIAKWFDTKIKDTYIKIIGEYKDCTFANNWLKK
>Mature_475_residues
MLLKKLQLKTIDYKLVLTMCFLLFFTSIVSAQEIIKDVVAEKPAEPVHGKQKIDGIIATVGDYIVLDSDIDKGYLEISSQ
GGNIKDITRCQMLGKLLEDKLYAHQAIQDSIIVSDAEVRGMMEERLNYMIQQVGDINKVVEYYKKSSVEEFKTYFADILK
EQKLASEMRDKIVKDVEITPEEVRNFFRKIPKDELPTFGAEMEVAQIVVEPKVSKEDKQKVIDRLNAIRKDVLEGSSFAT
KAVLYSQDPGSAPNGGYYKMTRKTPFVKEFKDVAFSLQEGEISAPFETTFGYHIIMVDKIKGQEVELRHILIAPTVSESA
LKEAKERIANIRAKIVSKELTFADAARTESDEKETRANGGTLINPNTQDTRFELTKMDPTLYGQVSNLKDDEVSQPLLNT
DDKGKKTYKLITVTNRIDEHTADYAKDYTKIKELALKEKQINAIAKWFDTKIKDTYIKIIGEYKDCTFANNWLKK

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=414, Percent_Identity=22.7053140096618, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 54056; Mature: 54056

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKKLQLKTIDYKLVLTMCFLLFFTSIVSAQEIIKDVVAEKPAEPVHGKQKIDGIIATV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GDYIVLDSDIDKGYLEISSQGGNIKDITRCQMLGKLLEDKLYAHQAIQDSIIVSDAEVRG
CCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHH
MMEERLNYMIQQVGDINKVVEYYKKSSVEEFKTYFADILKEQKLASEMRDKIVKDVEITP
HHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEVRNFFRKIPKDELPTFGAEMEVAQIVVEPKVSKEDKQKVIDRLNAIRKDVLEGSSFAT
HHHHHHHHHCCHHHCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
KAVLYSQDPGSAPNGGYYKMTRKTPFVKEFKDVAFSLQEGEISAPFETTFGYHIIMVDKI
EEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
KGQEVELRHILIAPTVSESALKEAKERIANIRAKIVSKELTFADAARTESDEKETRANGG
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
TLINPNTQDTRFELTKMDPTLYGQVSNLKDDEVSQPLLNTDDKGKKTYKLITVTNRIDEH
EEECCCCCCCEEEEEECCCHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECHHHHH
TADYAKDYTKIKELALKEKQINAIAKWFDTKIKDTYIKIIGEYKDCTFANNWLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
>Mature Secondary Structure
MLLKKLQLKTIDYKLVLTMCFLLFFTSIVSAQEIIKDVVAEKPAEPVHGKQKIDGIIATV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GDYIVLDSDIDKGYLEISSQGGNIKDITRCQMLGKLLEDKLYAHQAIQDSIIVSDAEVRG
CCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHH
MMEERLNYMIQQVGDINKVVEYYKKSSVEEFKTYFADILKEQKLASEMRDKIVKDVEITP
HHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEVRNFFRKIPKDELPTFGAEMEVAQIVVEPKVSKEDKQKVIDRLNAIRKDVLEGSSFAT
HHHHHHHHHCCHHHCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
KAVLYSQDPGSAPNGGYYKMTRKTPFVKEFKDVAFSLQEGEISAPFETTFGYHIIMVDKI
EEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
KGQEVELRHILIAPTVSESALKEAKERIANIRAKIVSKELTFADAARTESDEKETRANGG
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
TLINPNTQDTRFELTKMDPTLYGQVSNLKDDEVSQPLLNTDDKGKKTYKLITVTNRIDEH
EEECCCCCCCEEEEEECCCHHHCCCCCCCCHHHCCCCCCCCCCCCCEEEEEEEECHHHHH
TADYAKDYTKIKELALKEKQINAIAKWFDTKIKDTYIKIIGEYKDCTFANNWLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA