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The map label for this gene is algB [H]

Identifier: 146299092

GI number: 146299092

Start: 1524110

End: 1525453

Strand: Direct

Name: algB [H]

Synonym: Fjoh_1332

Alternate gene names: 146299092

Gene position: 1524110-1525453 (Clockwise)

Preceding gene: 146299088

Following gene: 146299093

Centisome position: 25.0

GC content: 35.12

Gene sequence:

>1344_bases
ATGAGAAAAAAGCAAGCCCAAATATTAGTTGTTGACGACCAGGAAGAAATTCTTTTTTCGGCAAAAATGATTCTCAAAAA
ACATTTTGAAACCATTTTCACGACCAACAGCCCCAAAAAAATCATTTCAATTTTGAATGAAAATGAAATAAATGTGGTTT
TGCTGGACATGAATTACCGAATTGGTTTTGAAGACGGGCGCGAAGGAATTCATTGGCTCAAAGAAATAAAAACGCTTTCG
CCTAATACAATTGTAATTTTAATGACCGCTTTTGGAAAAATAGAAACCGCTGTTGAAGGCATTAAAATTGGCGCTTTTGA
TTATGTTTTAAAACCATGGCATAACGAAAAATTACTTGAAATTATTGATAAAGCTGTCGCCGAAAGCAGAAAAAACACTA
AAAAGGTAATTGCAGAAAAAACAGAAAAACGATATTTTACAGGAACTTCCCAAAAAATAAAACAAGCCTATTCTGTAGCC
GAAAAAGTCGCCAGAACAGATGCTAATGTTTTGATATTGGGAGAAAACGGAACCGGGAAATATGTTTTTGCCGAATTTAT
CCATCAAAATTCTGAAAGAAAAAATCAGCCTTTTGTGCATGTAGATTTAGGATCGTTGAGCGATAATTTATTCGAAAGCG
AATTGTTTGGGTATGCAAAAGGGGCTTTTACAGATGCTAAAACCGATACGCCGGGAAGATTTGAAACAGCGCAGAACGGC
ACTATTTTTCTTGATGAAATAGGAAATATTCCGCTTCATCTTCAGGCGAAACTGCTTCATATTTTACAAACCAAAACATT
GACCAGATTAGGAGAAAGTAAACCACGTCCGTTAAATGTTCGTGTTATTGCGGCCACAAACAGTGATATTAAATCTGAAG
TAAAAAACAAAACTTTCCGAGAAGATTTGCTTTACCGAATTAATACAATGGAAATAAATCTTCCGCCTCTGCGTGAACGA
AAAGACGACATAGTTCCGATGGCAAATTTTATATTAGAAAATATCGCCCAAAAGTACAATCAGGAAAATTGGCGTTTTGA
TGAAAATGTATCACCATATCTGGAAAGATATCCGTGGAAAGGAAATGTTCGTGAAATGGAAAACAAAATCGAACGCGCTC
TTATTTTAGCTGAAAACAATACAATTTCTGTAACCGATTTAGACATTCTTGATTTTGAGGAAATTCAGGAAAATGACGAT
AATCCGTTATCTGAAATGGAGAAAACAGCAATCGAAAAAGCACTTTTTAAACATCACGGAAACATCTCTAAAACCGCCGA
AGAACTAGGATTGTCAAGAGCTGCGTTGTATAGAAGAATTGAGAAGTACGATTTGAAGAATTAA

Upstream 100 bases:

>100_bases
TTGTAAAGCACTGATTTTAAAGAAGCTCTAAAAACCATTCAAAAAACAAGTGTTCGATAATGAACAGTTGACCGTTCAAA
AGCGGACAAAAAAACGCAGC

Downstream 100 bases:

>100_bases
AAAGAAAAAGCAAGAGGCAAGAATTAAGATTTTTTTATCGACTTAAATCTGCAAAATCTGTGTGAAACAAAAAAATAAAG
ACAAGAGCTAAAATTATTTT

Product: two component sigma-54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRKKQAQILVVDDQEEILFSAKMILKKHFETIFTTNSPKKIISILNENEINVVLLDMNYRIGFEDGREGIHWLKEIKTLS
PNTIVILMTAFGKIETAVEGIKIGAFDYVLKPWHNEKLLEIIDKAVAESRKNTKKVIAEKTEKRYFTGTSQKIKQAYSVA
EKVARTDANVLILGENGTGKYVFAEFIHQNSERKNQPFVHVDLGSLSDNLFESELFGYAKGAFTDAKTDTPGRFETAQNG
TIFLDEIGNIPLHLQAKLLHILQTKTLTRLGESKPRPLNVRVIAATNSDIKSEVKNKTFREDLLYRINTMEINLPPLRER
KDDIVPMANFILENIAQKYNQENWRFDENVSPYLERYPWKGNVREMENKIERALILAENNTISVTDLDILDFEEIQENDD
NPLSEMEKTAIEKALFKHHGNISKTAEELGLSRAALYRRIEKYDLKN

Sequences:

>Translated_447_residues
MRKKQAQILVVDDQEEILFSAKMILKKHFETIFTTNSPKKIISILNENEINVVLLDMNYRIGFEDGREGIHWLKEIKTLS
PNTIVILMTAFGKIETAVEGIKIGAFDYVLKPWHNEKLLEIIDKAVAESRKNTKKVIAEKTEKRYFTGTSQKIKQAYSVA
EKVARTDANVLILGENGTGKYVFAEFIHQNSERKNQPFVHVDLGSLSDNLFESELFGYAKGAFTDAKTDTPGRFETAQNG
TIFLDEIGNIPLHLQAKLLHILQTKTLTRLGESKPRPLNVRVIAATNSDIKSEVKNKTFREDLLYRINTMEINLPPLRER
KDDIVPMANFILENIAQKYNQENWRFDENVSPYLERYPWKGNVREMENKIERALILAENNTISVTDLDILDFEEIQENDD
NPLSEMEKTAIEKALFKHHGNISKTAEELGLSRAALYRRIEKYDLKN
>Mature_447_residues
MRKKQAQILVVDDQEEILFSAKMILKKHFETIFTTNSPKKIISILNENEINVVLLDMNYRIGFEDGREGIHWLKEIKTLS
PNTIVILMTAFGKIETAVEGIKIGAFDYVLKPWHNEKLLEIIDKAVAESRKNTKKVIAEKTEKRYFTGTSQKIKQAYSVA
EKVARTDANVLILGENGTGKYVFAEFIHQNSERKNQPFVHVDLGSLSDNLFESELFGYAKGAFTDAKTDTPGRFETAQNG
TIFLDEIGNIPLHLQAKLLHILQTKTLTRLGESKPRPLNVRVIAATNSDIKSEVKNKTFREDLLYRINTMEINLPPLRER
KDDIVPMANFILENIAQKYNQENWRFDENVSPYLERYPWKGNVREMENKIERALILAENNTISVTDLDILDFEEIQENDD
NPLSEMEKTAIEKALFKHHGNISKTAEELGLSRAALYRRIEKYDLKN

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=37.4458874458874, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=36.4464692482916, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1788905, Length=452, Percent_Identity=33.1858407079646, Blast_Score=248, Evalue=8e-67,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=30.4904051172708, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87082117, Length=235, Percent_Identity=45.531914893617, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=35.8255451713396, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=34.7692307692308, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1789087, Length=305, Percent_Identity=38.6885245901639, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1786524, Length=333, Percent_Identity=36.036036036036, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=288, Percent_Identity=36.4583333333333, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787583, Length=308, Percent_Identity=32.7922077922078, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=30.3754266211604, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789828, Length=245, Percent_Identity=33.469387755102, Blast_Score=118, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51390; Mature: 51390

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKQAQILVVDDQEEILFSAKMILKKHFETIFTTNSPKKIISILNENEINVVLLDMNYR
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCEE
IGFEDGREGIHWLKEIKTLSPNTIVILMTAFGKIETAVEGIKIGAFDYVLKPWHNEKLLE
ECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCEEECHHHHHHCCCCCCHHHH
IIDKAVAESRKNTKKVIAEKTEKRYFTGTSQKIKQAYSVAEKVARTDANVLILGENGTGK
HHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
YVFAEFIHQNSERKNQPFVHVDLGSLSDNLFESELFGYAKGAFTDAKTDTPGRFETAQNG
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TIFLDEIGNIPLHLQAKLLHILQTKTLTRLGESKPRPLNVRVIAATNSDIKSEVKNKTFR
EEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
EDLLYRINTMEINLPPLRERKDDIVPMANFILENIAQKYNQENWRFDENVSPYLERYPWK
HHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
GNVREMENKIERALILAENNTISVTDLDILDFEEIQENDDNPLSEMEKTAIEKALFKHHG
CCHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
NISKTAEELGLSRAALYRRIEKYDLKN
CHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKKQAQILVVDDQEEILFSAKMILKKHFETIFTTNSPKKIISILNENEINVVLLDMNYR
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCEE
IGFEDGREGIHWLKEIKTLSPNTIVILMTAFGKIETAVEGIKIGAFDYVLKPWHNEKLLE
ECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCEEECHHHHHHCCCCCCHHHH
IIDKAVAESRKNTKKVIAEKTEKRYFTGTSQKIKQAYSVAEKVARTDANVLILGENGTGK
HHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
YVFAEFIHQNSERKNQPFVHVDLGSLSDNLFESELFGYAKGAFTDAKTDTPGRFETAQNG
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TIFLDEIGNIPLHLQAKLLHILQTKTLTRLGESKPRPLNVRVIAATNSDIKSEVKNKTFR
EEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
EDLLYRINTMEINLPPLRERKDDIVPMANFILENIAQKYNQENWRFDENVSPYLERYPWK
HHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
GNVREMENKIERALILAENNTISVTDLDILDFEEIQENDDNPLSEMEKTAIEKALFKHHG
CCHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
NISKTAEELGLSRAALYRRIEKYDLKN
CHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1899859; 1738315; 10984043; 9473053 [H]