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The map label for this gene is ntrY [H]

Identifier: 146299093

GI number: 146299093

Start: 1525587

End: 1526912

Strand: Direct

Name: ntrY [H]

Synonym: Fjoh_1333

Alternate gene names: 146299093

Gene position: 1525587-1526912 (Clockwise)

Preceding gene: 146299092

Following gene: 146299099

Centisome position: 25.02

GC content: 33.03

Gene sequence:

>1326_bases
ATGAAAAACTGGAAATTTTATAATGCATTTTTTGTGAGAGTTCTGTTCGTTATGACGCTCTTCTTTGTCTGTTTTTTCCT
TATCTATAAAATGTTTTATTTCAATGCGCTTTTGGTTGGTTTTTTCGCATTTTTAACGCTAGCCGAAATGTATTTTTTTG
TAAAAAACCAATTGCAGTTTTACGACAGAACTTTGTTTTCGATTTTACAGAATGATTTTTCAACCAACTTTCCTGAGGAG
AATAAAAGAGATAATTTTAAAAGTTTATATCTTTTATATGAAACGCTCAAAGTACAGCAGCAAGAACAAAAATCGAAGGA
ACTAATTTATCGTTCGCTTTTAAACAATATTGATTCTGCAGCTTTAATTCTGGAAAAAGAAAATAATGACTGGAATATTT
TCCTGATGAATGACTGCTTCTCGGACCTATTTAAAGTGCCAAAAGTAAGCCATTGGAAATATCTTAAAAACTATCTGCCG
TCACTTTGCAATGAAATTGAAAAAACGGAGTTCGGTGAATTAAAATCGGCAATTTCGATTAAAATTGAAGATCAGGATCT
GCAGACTTTTATGCTCCAGACTTCAAGAACACAAACCTATAACAAAGAATATTATATTATTTTATTAGACAGCATTCAGC
GTGTTATTGAGAAAAAAGAAAAAGAAGCCTGGATTAATTTGATGAAGATTATTTCGCATGAATTAATGAATTCCTTAACG
CCAATTCGAGCGCTTTCGCAGAATCTGCTTCATATTGTCGATCAGGAAAATTTAGAAGAAGATGATTTTGATGACATTAA
AAGCAGTATTTCCACGATTATAAACCGAAGCGATCATTTGCAGGTTTTTGTTGAAAATTACCGAAAACTGGCCATGCTGC
CAACTCCATCAAAACAAATGACGCCAATTAACGCTTTATTTGATGACTGTCTTAGAATCATGAGTCCTATTTTGAAAGCA
GAAAACATTGAATTAATAAGTGATATTCATAGTTCGCGTTCGATTTTGATAGATAAAAACCAGATGGAACAGGTAATTAT
TAATTTGATTACCAACAGCGTGTATGCTTTAAAAGAAAAGAATGAAAAGAAAATGTATGTGTCGAGTTATACCGAAAACA
ATCGTTTTTTTATCACGATTTCTGATAACGGAAAAGGAATCGATCCAGAAATTCAGGACAAAGTATTCCTGCCTTTTTTC
ACCACCAGAAAAGACGGTGCGGGAATTGGTTTAACGCTTTCTAAAAACATCATCGAAGCGCACGGCGGTTATTTAAGCTA
CCAAACCGATGAAGATAAAACCAGTTTTGTGATCTGTTTGATCTAG

Upstream 100 bases:

>100_bases
TTTATCGACTTAAATCTGCAAAATCTGTGTGAAACAAAAAAATAAAGACAAGAGCTAAAATTATTTTAATCATTTTAATC
TGTGGCTAAAAAATAAAGGA

Downstream 100 bases:

>100_bases
TTTTTTTGAACCATATAAGTGATATAAGTCTAACCCTGGATTTCTGGTTTCCAAAAGTGCTTTTCAAAATCTACAATTTG
ATTGTCAACCACTTTAATGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKNWKFYNAFFVRVLFVMTLFFVCFFLIYKMFYFNALLVGFFAFLTLAEMYFFVKNQLQFYDRTLFSILQNDFSTNFPEE
NKRDNFKSLYLLYETLKVQQQEQKSKELIYRSLLNNIDSAALILEKENNDWNIFLMNDCFSDLFKVPKVSHWKYLKNYLP
SLCNEIEKTEFGELKSAISIKIEDQDLQTFMLQTSRTQTYNKEYYIILLDSIQRVIEKKEKEAWINLMKIISHELMNSLT
PIRALSQNLLHIVDQENLEEDDFDDIKSSISTIINRSDHLQVFVENYRKLAMLPTPSKQMTPINALFDDCLRIMSPILKA
ENIELISDIHSSRSILIDKNQMEQVIINLITNSVYALKEKNEKKMYVSSYTENNRFFITISDNGKGIDPEIQDKVFLPFF
TTRKDGAGIGLTLSKNIIEAHGGYLSYQTDEDKTSFVICLI

Sequences:

>Translated_441_residues
MKNWKFYNAFFVRVLFVMTLFFVCFFLIYKMFYFNALLVGFFAFLTLAEMYFFVKNQLQFYDRTLFSILQNDFSTNFPEE
NKRDNFKSLYLLYETLKVQQQEQKSKELIYRSLLNNIDSAALILEKENNDWNIFLMNDCFSDLFKVPKVSHWKYLKNYLP
SLCNEIEKTEFGELKSAISIKIEDQDLQTFMLQTSRTQTYNKEYYIILLDSIQRVIEKKEKEAWINLMKIISHELMNSLT
PIRALSQNLLHIVDQENLEEDDFDDIKSSISTIINRSDHLQVFVENYRKLAMLPTPSKQMTPINALFDDCLRIMSPILKA
ENIELISDIHSSRSILIDKNQMEQVIINLITNSVYALKEKNEKKMYVSSYTENNRFFITISDNGKGIDPEIQDKVFLPFF
TTRKDGAGIGLTLSKNIIEAHGGYLSYQTDEDKTSFVICLI
>Mature_441_residues
MKNWKFYNAFFVRVLFVMTLFFVCFFLIYKMFYFNALLVGFFAFLTLAEMYFFVKNQLQFYDRTLFSILQNDFSTNFPEE
NKRDNFKSLYLLYETLKVQQQEQKSKELIYRSLLNNIDSAALILEKENNDWNIFLMNDCFSDLFKVPKVSHWKYLKNYLP
SLCNEIEKTEFGELKSAISIKIEDQDLQTFMLQTSRTQTYNKEYYIILLDSIQRVIEKKEKEAWINLMKIISHELMNSLT
PIRALSQNLLHIVDQENLEEDDFDDIKSSISTIINRSDHLQVFVENYRKLAMLPTPSKQMTPINALFDDCLRIMSPILKA
ENIELISDIHSSRSILIDKNQMEQVIINLITNSVYALKEKNEKKMYVSSYTENNRFFITISDNGKGIDPEIQDKVFLPFF
TTRKDGAGIGLTLSKNIIEAHGGYLSYQTDEDKTSFVICLI

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=29.4392523364486, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=342, Percent_Identity=23.0994152046784, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=26.3598326359833, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=27.3504273504274, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51950; Mature: 51950

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWKFYNAFFVRVLFVMTLFFVCFFLIYKMFYFNALLVGFFAFLTLAEMYFFVKNQLQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDRTLFSILQNDFSTNFPEENKRDNFKSLYLLYETLKVQQQEQKSKELIYRSLLNNIDSA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALILEKENNDWNIFLMNDCFSDLFKVPKVSHWKYLKNYLPSLCNEIEKTEFGELKSAISI
EEEEEECCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
KIEDQDLQTFMLQTSRTQTYNKEYYIILLDSIQRVIEKKEKEAWINLMKIISHELMNSLT
EEECCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIRALSQNLLHIVDQENLEEDDFDDIKSSISTIINRSDHLQVFVENYRKLAMLPTPSKQM
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC
TPINALFDDCLRIMSPILKAENIELISDIHSSRSILIDKNQMEQVIINLITNSVYALKEK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCC
NEKKMYVSSYTENNRFFITISDNGKGIDPEIQDKVFLPFFTTRKDGAGIGLTLSKNIIEA
CCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECHHHHHH
HGGYLSYQTDEDKTSFVICLI
CCCEEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MKNWKFYNAFFVRVLFVMTLFFVCFFLIYKMFYFNALLVGFFAFLTLAEMYFFVKNQLQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDRTLFSILQNDFSTNFPEENKRDNFKSLYLLYETLKVQQQEQKSKELIYRSLLNNIDSA
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALILEKENNDWNIFLMNDCFSDLFKVPKVSHWKYLKNYLPSLCNEIEKTEFGELKSAISI
EEEEEECCCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
KIEDQDLQTFMLQTSRTQTYNKEYYIILLDSIQRVIEKKEKEAWINLMKIISHELMNSLT
EEECCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIRALSQNLLHIVDQENLEEDDFDDIKSSISTIINRSDHLQVFVENYRKLAMLPTPSKQM
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC
TPINALFDDCLRIMSPILKAENIELISDIHSSRSILIDKNQMEQVIINLITNSVYALKEK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHCC
NEKKMYVSSYTENNRFFITISDNGKGIDPEIQDKVFLPFFTTRKDGAGIGLTLSKNIIEA
CCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECHHHHHH
HGGYLSYQTDEDKTSFVICLI
CCCEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]