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The map label for this gene is hflX [H]

Identifier: 146298932

GI number: 146298932

Start: 1324996

End: 1326225

Strand: Direct

Name: hflX [H]

Synonym: Fjoh_1171

Alternate gene names: 146298932

Gene position: 1324996-1326225 (Clockwise)

Preceding gene: 146298931

Following gene: 146298939

Centisome position: 21.73

GC content: 35.28

Gene sequence:

>1230_bases
ATGCTAGAGAAAGAAGTTATAAATTTTGAGAAAACAGCCATTGTAGGTATTGTAACTCAAAATCAGAGTGAGGAAAAACT
TAATGAATATTTAGACGAATTAGAGTTTTTAACTTTTACCGCTGGCGGAGAAGTTATTAAACGTTTTTCGCAGAAAATGG
AACGCCCTAATCCGAAGACTTTTGTCGGAACGGGAAAAATAGATGAAATCAATCTTTTTGTAAAAGAAAACAAAATATCG
ACAGTTATTTTTGATGATGAGCTGACACCTTCTCAGCAAAAAAATATTTCAAGAATTATCGATTGTAAAATCCTTGACAG
AACCAATTTGATTTTGGATATTTTTGCGCAGAGAGCCGAAACTTCGTATGCAAGGACACAGGTTGAATTAGCGCAGTGTA
TTTATTTACTGCCAAGACTTTCTGGTTTATGGACACACCTTGAGCGTCAAAAAGGGGGAATTGGTATGCGTGGTCCCGGT
GAAACTGAAATCGAAACAGACAGACGTATTGTTCGTGACCGTATTTCGTTATTGAAAGAGAAAATCAAAACGATCGATAA
ACAAATGAGCATTCAGCGTAGCAATCGTGGTGCAATGGTTCGTGTGGCACTTGTTGGTTATACCAATGTTGGAAAATCGA
CTTTGATGAATGCTATTGGAAAAAGTGAGGTCTTTGTTGAAAATAAATTGTTTGCAACTTTAGATACAACCGTTAGAAAA
GTTGTAATTAAAAACCTGCCGTTTTTACTTTCGGATACGGTTGGATTTATTAGAAAACTGCCCACTCAATTGGTTGATTC
CTTCAAGAGTACACTTGATGAGGTTCGTGAAGCTGATTTACTTTTGCACGTTGTAGATATTTCTCATCCTGATTTCGAAG
ACCACATTGAATCTGTAAATCAGATTTTACAGGAAATAAAAAGTAATGATAAGCCAACGATTATGGTTTTTAACAAAATC
GATGCTTACAAACACCTTACAATTGACGACGATGATTTAATCACCGAAAGAACCAGAAAACACTGGACACTAGACGAATG
GAAGCAAACCTGGATGAGTAATGTAGGTCATGATAAAGCATTATTTATCTCGGCAACTCAAAAGGAAAATTTTGAAGAAT
TTAGAGAAATGGTTTACGAAGCTGTTCGTCAGATTCATATTACCCGATTTCCATATAATAACTTTTTATATCCTGATTAT
AAGGATGCTATTGAAAAGGAAGAAGAATAA

Upstream 100 bases:

>100_bases
CCTGATTTGTAAATGGTTTATTTTTTTATAGAATTTAAAATTGAAATTCTATAATTGTAGTAGTTTACAAATGATTAAAT
TTGCAGGATTATTTTAAGAT

Downstream 100 bases:

>100_bases
AATAAAAACGGCTTTTGAAATTTCAAAAGCCGTTTTTTTATAAATTAGATTAGAAGTTATATTCTTATCTTTGTAGTAAT
GAGTAAGAATTTATATATAA

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLEKEVINFEKTAIVGIVTQNQSEEKLNEYLDELEFLTFTAGGEVIKRFSQKMERPNPKTFVGTGKIDEINLFVKENKIS
TVIFDDELTPSQQKNISRIIDCKILDRTNLILDIFAQRAETSYARTQVELAQCIYLLPRLSGLWTHLERQKGGIGMRGPG
ETEIETDRRIVRDRISLLKEKIKTIDKQMSIQRSNRGAMVRVALVGYTNVGKSTLMNAIGKSEVFVENKLFATLDTTVRK
VVIKNLPFLLSDTVGFIRKLPTQLVDSFKSTLDEVREADLLLHVVDISHPDFEDHIESVNQILQEIKSNDKPTIMVFNKI
DAYKHLTIDDDDLITERTRKHWTLDEWKQTWMSNVGHDKALFISATQKENFEEFREMVYEAVRQIHITRFPYNNFLYPDY
KDAIEKEEE

Sequences:

>Translated_409_residues
MLEKEVINFEKTAIVGIVTQNQSEEKLNEYLDELEFLTFTAGGEVIKRFSQKMERPNPKTFVGTGKIDEINLFVKENKIS
TVIFDDELTPSQQKNISRIIDCKILDRTNLILDIFAQRAETSYARTQVELAQCIYLLPRLSGLWTHLERQKGGIGMRGPG
ETEIETDRRIVRDRISLLKEKIKTIDKQMSIQRSNRGAMVRVALVGYTNVGKSTLMNAIGKSEVFVENKLFATLDTTVRK
VVIKNLPFLLSDTVGFIRKLPTQLVDSFKSTLDEVREADLLLHVVDISHPDFEDHIESVNQILQEIKSNDKPTIMVFNKI
DAYKHLTIDDDDLITERTRKHWTLDEWKQTWMSNVGHDKALFISATQKENFEEFREMVYEAVRQIHITRFPYNNFLYPDY
KDAIEKEEE
>Mature_409_residues
MLEKEVINFEKTAIVGIVTQNQSEEKLNEYLDELEFLTFTAGGEVIKRFSQKMERPNPKTFVGTGKIDEINLFVKENKIS
TVIFDDELTPSQQKNISRIIDCKILDRTNLILDIFAQRAETSYARTQVELAQCIYLLPRLSGLWTHLERQKGGIGMRGPG
ETEIETDRRIVRDRISLLKEKIKTIDKQMSIQRSNRGAMVRVALVGYTNVGKSTLMNAIGKSEVFVENKLFATLDTTVRK
VVIKNLPFLLSDTVGFIRKLPTQLVDSFKSTLDEVREADLLLHVVDISHPDFEDHIESVNQILQEIKSNDKPTIMVFNKI
DAYKHLTIDDDDLITERTRKHWTLDEWKQTWMSNVGHDKALFISATQKENFEEFREMVYEAVRQIHITRFPYNNFLYPDY
KDAIEKEEE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310133116, Length=212, Percent_Identity=30.6603773584906, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310124269, Length=199, Percent_Identity=30.6532663316583, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124267, Length=199, Percent_Identity=30.6532663316583, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124171, Length=199, Percent_Identity=30.6532663316583, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124169, Length=199, Percent_Identity=30.6532663316583, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1790615, Length=302, Percent_Identity=48.3443708609272, Blast_Score=290, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17561038, Length=250, Percent_Identity=34, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24650079, Length=297, Percent_Identity=28.2828282828283, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47428; Mature: 47428

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKEVINFEKTAIVGIVTQNQSEEKLNEYLDELEFLTFTAGGEVIKRFSQKMERPNPKT
CCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCCCCE
FVGTGKIDEINLFVKENKISTVIFDDELTPSQQKNISRIIDCKILDRTNLILDIFAQRAE
EEECCCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHH
TSYARTQVELAQCIYLLPRLSGLWTHLERQKGGIGMRGPGETEIETDRRIVRDRISLLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KIKTIDKQMSIQRSNRGAMVRVALVGYTNVGKSTLMNAIGKSEVFVENKLFATLDTTVRK
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHH
VVIKNLPFLLSDTVGFIRKLPTQLVDSFKSTLDEVREADLLLHVVDISHPDFEDHIESVN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
QILQEIKSNDKPTIMVFNKIDAYKHLTIDDDDLITERTRKHWTLDEWKQTWMSNVGHDKA
HHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
LFISATQKENFEEFREMVYEAVRQIHITRFPYNNFLYPDYKDAIEKEEE
EEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MLEKEVINFEKTAIVGIVTQNQSEEKLNEYLDELEFLTFTAGGEVIKRFSQKMERPNPKT
CCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCCCCE
FVGTGKIDEINLFVKENKISTVIFDDELTPSQQKNISRIIDCKILDRTNLILDIFAQRAE
EEECCCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHH
TSYARTQVELAQCIYLLPRLSGLWTHLERQKGGIGMRGPGETEIETDRRIVRDRISLLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
KIKTIDKQMSIQRSNRGAMVRVALVGYTNVGKSTLMNAIGKSEVFVENKLFATLDTTVRK
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHH
VVIKNLPFLLSDTVGFIRKLPTQLVDSFKSTLDEVREADLLLHVVDISHPDFEDHIESVN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHH
QILQEIKSNDKPTIMVFNKIDAYKHLTIDDDDLITERTRKHWTLDEWKQTWMSNVGHDKA
HHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCE
LFISATQKENFEEFREMVYEAVRQIHITRFPYNNFLYPDYKDAIEKEEE
EEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]