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The map label for this gene is rnc [H]

Identifier: 146298900

GI number: 146298900

Start: 1286418

End: 1287158

Strand: Direct

Name: rnc [H]

Synonym: Fjoh_1139

Alternate gene names: 146298900

Gene position: 1286418-1287158 (Clockwise)

Preceding gene: 146298899

Following gene: 146298901

Centisome position: 21.1

GC content: 33.06

Gene sequence:

>741_bases
ATGAATATTATCAAAAAAATATTTTCTAAATCCCGTTCTCTAGAAGACGGGATTTTTTTTGACACTATTCAGAAAATTCT
TGGTTTTCAGCCTATAAATATCGAATTTTATAAAAAAGCCTTTACACATAGATCATCAAACAAATTAGATGAAGCAGGAC
ATCCTATAAATTACGAAAGACTTGAATTTTTAGGAGATGCAATGTTAAGTGCTGTAATTGCTGCACATTTGTTTAATAAG
GCGCCAAATGGAGACGAAGGTTATTTAACAAAAATGCGTTCAAAAATCGTGAGCCGCGAACATTTAAATGAACTTGGCAA
AGATTTGAATTTAGTGCGTTTTGTAGAGAGCAAAGTACCAGTACAGCATTTTGGAGAAAACATTCATGGTAATATTTTCG
AATCGCTTATTGGAGCTATATATTTAGATAAAGGATATTCGTACTGCGAAAGATTTATTCAAAAAAGAGTAATTACGCCT
TATGTTGATATTGCGAGACTCGAAGGAAAAGTAATTAGTTATAAAAGTTTAGTTATCGAATGGTGTCAGAAAGAAAAGAG
AATCTTTCACTACGACATTTTTGAAGATAATGGCATCGACGGACAGCGTTTGTTTGGTGTCAAATTAAGTATAGACGATA
AAGTGGTCGCAAGAGCGCGGGCAACTTCAAAAAAGAAAGCAGAAGAAAAAGCTTCGCAAAGAGCCTATTTTGCATTTCAG
GAAAAAATTGACAAGAAATAA

Upstream 100 bases:

>100_bases
TCAAAAAAGAGAAGTGAATGTTGCTATGAGTAACACGTTTGGTTTTGGCGGACACAATGCTTGTGTATTGTTTAAAAAAT
TAGCTGACTAATTTTCGGAT

Downstream 100 bases:

>100_bases
TTACAAAAATGCTGTAGTTTTCTTAACGCTAAATCGTTTTCGTTTATAAATTAATAAAAACAAGCTGCTTATAACTATTG
ATGCTCCGTTAGAAATAGTA

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNIIKKIFSKSRSLEDGIFFDTIQKILGFQPINIEFYKKAFTHRSSNKLDEAGHPINYERLEFLGDAMLSAVIAAHLFNK
APNGDEGYLTKMRSKIVSREHLNELGKDLNLVRFVESKVPVQHFGENIHGNIFESLIGAIYLDKGYSYCERFIQKRVITP
YVDIARLEGKVISYKSLVIEWCQKEKRIFHYDIFEDNGIDGQRLFGVKLSIDDKVVARARATSKKKAEEKASQRAYFAFQ
EKIDKK

Sequences:

>Translated_246_residues
MNIIKKIFSKSRSLEDGIFFDTIQKILGFQPINIEFYKKAFTHRSSNKLDEAGHPINYERLEFLGDAMLSAVIAAHLFNK
APNGDEGYLTKMRSKIVSREHLNELGKDLNLVRFVESKVPVQHFGENIHGNIFESLIGAIYLDKGYSYCERFIQKRVITP
YVDIARLEGKVISYKSLVIEWCQKEKRIFHYDIFEDNGIDGQRLFGVKLSIDDKVVARARATSKKKAEEKASQRAYFAFQ
EKIDKK
>Mature_246_residues
MNIIKKIFSKSRSLEDGIFFDTIQKILGFQPINIEFYKKAFTHRSSNKLDEAGHPINYERLEFLGDAMLSAVIAAHLFNK
APNGDEGYLTKMRSKIVSREHLNELGKDLNLVRFVESKVPVQHFGENIHGNIFESLIGAIYLDKGYSYCERFIQKRVITP
YVDIARLEGKVISYKSLVIEWCQKEKRIFHYDIFEDNGIDGQRLFGVKLSIDDKVVARARATSKKKAEEKASQRAYFAFQ
EKIDKK

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=140, Percent_Identity=33.5714285714286, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17506883, Length=228, Percent_Identity=28.0701754385965, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193202651, Length=228, Percent_Identity=28.0701754385965, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17137682, Length=218, Percent_Identity=25.6880733944954, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28422; Mature: 28422

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIKKIFSKSRSLEDGIFFDTIQKILGFQPINIEFYKKAFTHRSSNKLDEAGHPINYER
CCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHCCCCCCHHH
LEFLGDAMLSAVIAAHLFNKAPNGDEGYLTKMRSKIVSREHLNELGKDLNLVRFVESKVP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VQHFGENIHGNIFESLIGAIYLDKGYSYCERFIQKRVITPYVDIARLEGKVISYKSLVIE
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHH
WCQKEKRIFHYDIFEDNGIDGQRLFGVKLSIDDKVVARARATSKKKAEEKASQRAYFAFQ
HHHHHCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDKK
HHHCCC
>Mature Secondary Structure
MNIIKKIFSKSRSLEDGIFFDTIQKILGFQPINIEFYKKAFTHRSSNKLDEAGHPINYER
CCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHCCCCCCHHH
LEFLGDAMLSAVIAAHLFNKAPNGDEGYLTKMRSKIVSREHLNELGKDLNLVRFVESKVP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VQHFGENIHGNIFESLIGAIYLDKGYSYCERFIQKRVITPYVDIARLEGKVISYKSLVIE
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHH
WCQKEKRIFHYDIFEDNGIDGQRLFGVKLSIDDKVVARARATSKKKAEEKASQRAYFAFQ
HHHHHCCEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIDKK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA