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The map label for this gene is uvrC

Identifier: 146298489

GI number: 146298489

Start: 800284

End: 802077

Strand: Direct

Name: uvrC

Synonym: Fjoh_0726

Alternate gene names: 146298489

Gene position: 800284-802077 (Clockwise)

Preceding gene: 146298486

Following gene: 146298490

Centisome position: 13.13

GC content: 34.0

Gene sequence:

>1794_bases
ATGTCAAAACCGTCCTTAGATCTTCAAATTCTCACCTTGCCGGATAATCCCGGCGTCTATCAATATTATGATAAAGACGG
GAAAATTCTATATGTCGGCAAAGCCAAAAATTTAAAAAAAAGGGTTTCCTCCTATTTCAATAAAATTCACGATACAGCCA
AAACAAATGTTTTGGTTAAAAAAATCGTGACTATAAAACATATCGTCGTTCCTACTGAAACTGACGCGCTTTTATTAGAA
AACAATTTAATTAAAACATTACAGCCTAGATATAATGTTTTGCTGCGTGATGATAAAAGCTATCCTTGGATTTGTATTAA
AAAAGAACCTTTTTCAAGAATATTTTTAACCCGAAGAATGGTAAAAGACGGATCTGAATATTTTGGTCCGTATACTAATT
TCAAGATGGTTTATACCATTTTGGATTTAATAAAAGAATTGTATCCGTTACGAACATGTAATTATGACTTGAGCCAGTCT
AATATTGATTCCGGCAAATTTAAAGTTTGTCTGGAATATCATATTGGCAATTGTAAAGGTCCGTGCGAAGGTTTAGAACC
TTTGGAAGAATATCAAAGACAAGTCAATGCAATTCGCGAAATTCTAAAAGGAAATTTCAAGGAAAGTTTAAAGGATTTTA
AAAAACTGATGAACAATTATGCGCAGAATTTACAATTTGAAGAAGCGCAGAAAATCAAAGAAAAAATAGAAGTTCTCGAA
AATTACCAGTCAAGATCGACAATTGTAAATCCGAAAATTACCAATATTGATGTATTTTCGATTATTTCTGATGAAAGTGC
TGCGTATGTTAACTTTTTACAGATTTCTCATGGATCGATTATTCGTTCGCATACTTTAGAAATGAAGAAAAAGCTGGACG
AAAGCGACGAAGAACTGCTGGAACTGGCGATTATTGAACTTCGTGAACGTTTCCAGTTGATGTCAAAAGAAATAATTGTT
CCTTTTGAAATTGATTTGGGCGAAAACATTAAAACAACCGTTCCCCAGCTTGGAGATAAAAAGCAGATCCTGGATTTATC
AATTCGAAATGCAAAATTCTACCGAATCGAACAATTAAAACAATTACAGATCGTAGATCCTGATCGTCACGTAAATCGAA
TTATGGCGCAAATGCAGAAAGATTTACGACTTCCGGTTGAACCTCGTCATATCGAATGTTTTGATAACTCGAATATTCAG
GGAACAAATCCTGTTGCGGCCTGCGTAGTTTTTAAAGACGGAAAACCAAGCAAAAAAGATTACCGACACTTTAATGTAAA
AACAGTTGAAGGCCCTGACGATTTTGCTTCGATGACCGAAATTGTGTATCGCCGTTACAAAAGATTATTAGATGAAAATC
AGCCTTTACCGCAATTAATTATTATTGATGGTGGAAAAGGACAATTATCATCGGCTTTAAAAAGTATTGACGAATTAGGT
TTAAGAGGTAAAGTTGCAATTATTGGAATTGCAAAACGTCTTGAAGAACTTTTTTATCCCGGAGATTCGATTCCGCTTTA
TTTAGATAAAAAATCCGAAACCTTAAAAGTTATTCAACAATTACGAAACGAGGCACATAGATTTGGTATTACATTTCACC
GAGACAAACGAAGCAAAGCTGCGCTTAATTCTTCGGTAGAAAGTATTCCCGGCATTGGCGAAAAAACCATGCTTACATTA
ATACAACATTTCAAAAGTGTTAAAAGATTGAAATTAGCGACAGAAAAAGAAATATCTGCCGTTGTCGGAGTATCAAAAGC
AAAAAAAATTGTCGACTTTTACAAAACCAATTAG

Upstream 100 bases:

>100_bases
GATTTCGTAAATTTGAAACTAAATCAATGTTAAGCTTTTTTCCAGAAAATCGGAATGGTTTTTGAAAACGCTAAACCTCT
ATCTTCAGAAATAAAACAGA

Downstream 100 bases:

>100_bases
CAGATTTTTATGCGCCTAAATCAACATTCTAACGTAACTACCCGATCAAAAGGATTCTTTTTAAATTCTATTTGCATCGC
GTCGTATGTATTTTTTATGC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSKPSLDLQILTLPDNPGVYQYYDKDGKILYVGKAKNLKKRVSSYFNKIHDTAKTNVLVKKIVTIKHIVVPTETDALLLE
NNLIKTLQPRYNVLLRDDKSYPWICIKKEPFSRIFLTRRMVKDGSEYFGPYTNFKMVYTILDLIKELYPLRTCNYDLSQS
NIDSGKFKVCLEYHIGNCKGPCEGLEPLEEYQRQVNAIREILKGNFKESLKDFKKLMNNYAQNLQFEEAQKIKEKIEVLE
NYQSRSTIVNPKITNIDVFSIISDESAAYVNFLQISHGSIIRSHTLEMKKKLDESDEELLELAIIELRERFQLMSKEIIV
PFEIDLGENIKTTVPQLGDKKQILDLSIRNAKFYRIEQLKQLQIVDPDRHVNRIMAQMQKDLRLPVEPRHIECFDNSNIQ
GTNPVAACVVFKDGKPSKKDYRHFNVKTVEGPDDFASMTEIVYRRYKRLLDENQPLPQLIIIDGGKGQLSSALKSIDELG
LRGKVAIIGIAKRLEELFYPGDSIPLYLDKKSETLKVIQQLRNEAHRFGITFHRDKRSKAALNSSVESIPGIGEKTMLTL
IQHFKSVKRLKLATEKEISAVVGVSKAKKIVDFYKTN

Sequences:

>Translated_597_residues
MSKPSLDLQILTLPDNPGVYQYYDKDGKILYVGKAKNLKKRVSSYFNKIHDTAKTNVLVKKIVTIKHIVVPTETDALLLE
NNLIKTLQPRYNVLLRDDKSYPWICIKKEPFSRIFLTRRMVKDGSEYFGPYTNFKMVYTILDLIKELYPLRTCNYDLSQS
NIDSGKFKVCLEYHIGNCKGPCEGLEPLEEYQRQVNAIREILKGNFKESLKDFKKLMNNYAQNLQFEEAQKIKEKIEVLE
NYQSRSTIVNPKITNIDVFSIISDESAAYVNFLQISHGSIIRSHTLEMKKKLDESDEELLELAIIELRERFQLMSKEIIV
PFEIDLGENIKTTVPQLGDKKQILDLSIRNAKFYRIEQLKQLQIVDPDRHVNRIMAQMQKDLRLPVEPRHIECFDNSNIQ
GTNPVAACVVFKDGKPSKKDYRHFNVKTVEGPDDFASMTEIVYRRYKRLLDENQPLPQLIIIDGGKGQLSSALKSIDELG
LRGKVAIIGIAKRLEELFYPGDSIPLYLDKKSETLKVIQQLRNEAHRFGITFHRDKRSKAALNSSVESIPGIGEKTMLTL
IQHFKSVKRLKLATEKEISAVVGVSKAKKIVDFYKTN
>Mature_596_residues
SKPSLDLQILTLPDNPGVYQYYDKDGKILYVGKAKNLKKRVSSYFNKIHDTAKTNVLVKKIVTIKHIVVPTETDALLLEN
NLIKTLQPRYNVLLRDDKSYPWICIKKEPFSRIFLTRRMVKDGSEYFGPYTNFKMVYTILDLIKELYPLRTCNYDLSQSN
IDSGKFKVCLEYHIGNCKGPCEGLEPLEEYQRQVNAIREILKGNFKESLKDFKKLMNNYAQNLQFEEAQKIKEKIEVLEN
YQSRSTIVNPKITNIDVFSIISDESAAYVNFLQISHGSIIRSHTLEMKKKLDESDEELLELAIIELRERFQLMSKEIIVP
FEIDLGENIKTTVPQLGDKKQILDLSIRNAKFYRIEQLKQLQIVDPDRHVNRIMAQMQKDLRLPVEPRHIECFDNSNIQG
TNPVAACVVFKDGKPSKKDYRHFNVKTVEGPDDFASMTEIVYRRYKRLLDENQPLPQLIIIDGGKGQLSSALKSIDELGL
RGKVAIIGIAKRLEELFYPGDSIPLYLDKKSETLKVIQQLRNEAHRFGITFHRDKRSKAALNSSVESIPGIGEKTMLTLI
QHFKSVKRLKLATEKEISAVVGVSKAKKIVDFYKTN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI87081999, Length=601, Percent_Identity=34.2762063227953, Blast_Score=336, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRC_FLAJ1 (A5FM03)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001193080.1
- ProteinModelPortal:   A5FM03
- STRING:   A5FM03
- GeneID:   5090760
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_0726
- eggNOG:   COG0322
- HOGENOM:   HBG566029
- OMA:   DVLYVGK
- ProtClustDB:   PRK00558
- BioCyc:   FJOH376686:FJOH_0726-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00203
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305
- SMART:   SM00465
- TIGRFAMs:   TIGR00194

Pfam domain/function: PF01541 GIY-YIG; PF08459 UvrC_HhH_N; SSF47781 RuvA_2_like; SSF46600 UvrB_C; SSF82771 UvrC_N

EC number: NA

Molecular weight: Translated: 68789; Mature: 68658

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50151 UVR; PS50164 UVRC_1; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPSLDLQILTLPDNPGVYQYYDKDGKILYVGKAKNLKKRVSSYFNKIHDTAKTNVLVK
CCCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KIVTIKHIVVPTETDALLLENNLIKTLQPRYNVLLRDDKSYPWICIKKEPFSRIFLTRRM
HHHHHHEEEECCCCCEEEECCCHHHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHH
VKDGSEYFGPYTNFKMVYTILDLIKELYPLRTCNYDLSQSNIDSGKFKVCLEYHIGNCKG
HHCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC
PCEGLEPLEEYQRQVNAIREILKGNFKESLKDFKKLMNNYAQNLQFEEAQKIKEKIEVLE
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NYQSRSTIVNPKITNIDVFSIISDESAAYVNFLQISHGSIIRSHTLEMKKKLDESDEELL
HHHHCCEECCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHH
ELAIIELRERFQLMSKEIIVPFEIDLGENIKTTVPQLGDKKQILDLSIRNAKFYRIEQLK
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHH
QLQIVDPDRHVNRIMAQMQKDLRLPVEPRHIECFDNSNIQGTNPVAACVVFKDGKPSKKD
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
YRHFNVKTVEGPDDFASMTEIVYRRYKRLLDENQPLPQLIIIDGGKGQLSSALKSIDELG
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHC
LRGKVAIIGIAKRLEELFYPGDSIPLYLDKKSETLKVIQQLRNEAHRFGITFHRDKRSKA
CCCCEEEEHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCHHHH
ALNSSVESIPGIGEKTMLTLIQHFKSVKRLKLATEKEISAVVGVSKAKKIVDFYKTN
HHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKPSLDLQILTLPDNPGVYQYYDKDGKILYVGKAKNLKKRVSSYFNKIHDTAKTNVLVK
CCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KIVTIKHIVVPTETDALLLENNLIKTLQPRYNVLLRDDKSYPWICIKKEPFSRIFLTRRM
HHHHHHEEEECCCCCEEEECCCHHHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHH
VKDGSEYFGPYTNFKMVYTILDLIKELYPLRTCNYDLSQSNIDSGKFKVCLEYHIGNCKG
HHCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC
PCEGLEPLEEYQRQVNAIREILKGNFKESLKDFKKLMNNYAQNLQFEEAQKIKEKIEVLE
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NYQSRSTIVNPKITNIDVFSIISDESAAYVNFLQISHGSIIRSHTLEMKKKLDESDEELL
HHHHCCEECCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHH
ELAIIELRERFQLMSKEIIVPFEIDLGENIKTTVPQLGDKKQILDLSIRNAKFYRIEQLK
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHH
QLQIVDPDRHVNRIMAQMQKDLRLPVEPRHIECFDNSNIQGTNPVAACVVFKDGKPSKKD
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
YRHFNVKTVEGPDDFASMTEIVYRRYKRLLDENQPLPQLIIIDGGKGQLSSALKSIDELG
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHC
LRGKVAIIGIAKRLEELFYPGDSIPLYLDKKSETLKVIQQLRNEAHRFGITFHRDKRSKA
CCCCEEEEHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCHHHH
ALNSSVESIPGIGEKTMLTLIQHFKSVKRLKLATEKEISAVVGVSKAKKIVDFYKTN
HHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA