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The map label for this gene is coaD [H]

Identifier: 146284314

GI number: 146284314

Start: 4340259

End: 4340870

Strand: Direct

Name: coaD [H]

Synonym: PST_4002

Alternate gene names: 146284314

Gene position: 4340259-4340870 (Clockwise)

Preceding gene: 146284313

Following gene: 146284315

Centisome position: 95.03

GC content: 61.76

Gene sequence:

>612_bases
GTGATCGCCTGCACAAGTCCTGAGATTGGCTCGCATTCGCGGCAGATCGCCGCATGGCCATTCAGACTTTACGCTGCCGA
TACCGAGCCGCTACCATCCACACCCCCACGCATGCGTCAGGACGCCGCGATGAATCGAGTGTTGTATCCGGGAACCTTCG
ATCCCATCACCATGGGCCACGCCGATCTGGTGGAACGTGCCTCGCGGCTGTTCGATGAGGTCATCATCGCCGTGGCGGCC
AACCCGAAGAAGAACCCGCTGTTCCCGCTGGAGCAACGCGTGGAGCTGGCCCGTGAAGTGACCAAGCACCTGCCGAACGT
GAAGGTCATCGGCTTCTCGACCCTGCTTGCCCACTTCGTCAAGGAACAGCAGGCCAACATCCTGCTGCGCGGCCTGCGCG
CGGTGTCCGACTTCGAATACGAATTCCAGCTGGCCAACATGAACCGGCAGCTGGCCCCGGACGTCGAAAGCCTGTTCCTC
ACGCCGTCGGAAAAGTACTCCTACATTTCCTCGACCCTGGTGCGCGAGATCGCCTCGCTCCAGGGCGACGTTTCGAAGTT
CGTGCATCCGGCCGTGATGCAGGCGCTCAAGACGCGCTTCGGCCAGAACTGA

Upstream 100 bases:

>100_bases
AATCTGTCCATTCACGACGGCTCGCTGTTTCCCACCAGCGTCGGCGCCAACCCGCAGCTGTCGATTTACGCCCTGTGCGC
GAAGCTGGCCACGCAGTTGG

Downstream 100 bases:

>100_bases
GGGCCGCCGTCGGCCCTGCGTCGAGTGCACGCCGAGCGTCGATGCGGCACAATTGGCCGTCGTAATTTAGCTGTGCCGTG
GTTCGAGCCACGGCAGGAGT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MIACTSPEIGSHSRQIAAWPFRLYAADTEPLPSTPPRMRQDAAMNRVLYPGTFDPITMGHADLVERASRLFDEVIIAVAA
NPKKNPLFPLEQRVELAREVTKHLPNVKVIGFSTLLAHFVKEQQANILLRGLRAVSDFEYEFQLANMNRQLAPDVESLFL
TPSEKYSYISSTLVREIASLQGDVSKFVHPAVMQALKTRFGQN

Sequences:

>Translated_203_residues
MIACTSPEIGSHSRQIAAWPFRLYAADTEPLPSTPPRMRQDAAMNRVLYPGTFDPITMGHADLVERASRLFDEVIIAVAA
NPKKNPLFPLEQRVELAREVTKHLPNVKVIGFSTLLAHFVKEQQANILLRGLRAVSDFEYEFQLANMNRQLAPDVESLFL
TPSEKYSYISSTLVREIASLQGDVSKFVHPAVMQALKTRFGQN
>Mature_203_residues
MIACTSPEIGSHSRQIAAWPFRLYAADTEPLPSTPPRMRQDAAMNRVLYPGTFDPITMGHADLVERASRLFDEVIIAVAA
NPKKNPLFPLEQRVELAREVTKHLPNVKVIGFSTLLAHFVKEQQANILLRGLRAVSDFEYEFQLANMNRQLAPDVESLFL
TPSEKYSYISSTLVREIASLQGDVSKFVHPAVMQALKTRFGQN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=57.6923076923077, Blast_Score=200, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 22795; Mature: 22795

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIACTSPEIGSHSRQIAAWPFRLYAADTEPLPSTPPRMRQDAAMNRVLYPGTFDPITMGH
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCEECCCCCCCCCCCH
ADLVERASRLFDEVIIAVAANPKKNPLFPLEQRVELAREVTKHLPNVKVIGFSTLLAHFV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
KEQQANILLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSEKYSYISSTLVREIASL
HHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
QGDVSKFVHPAVMQALKTRFGQN
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIACTSPEIGSHSRQIAAWPFRLYAADTEPLPSTPPRMRQDAAMNRVLYPGTFDPITMGH
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCEECCCCCCCCCCCH
ADLVERASRLFDEVIIAVAANPKKNPLFPLEQRVELAREVTKHLPNVKVIGFSTLLAHFV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
KEQQANILLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSEKYSYISSTLVREIASL
HHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
QGDVSKFVHPAVMQALKTRFGQN
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]