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The map label for this gene is yxnA [H]

Identifier: 146284199

GI number: 146284199

Start: 4215457

End: 4216467

Strand: Direct

Name: yxnA [H]

Synonym: PST_3887

Alternate gene names: 146284199

Gene position: 4215457-4216467 (Clockwise)

Preceding gene: 146284193

Following gene: 146284202

Centisome position: 92.29

GC content: 70.92

Gene sequence:

>1011_bases
ATGACCAGAGGACTTCCCATGCCAGAACCAACCGCGGTGATCTGTGGCGCGACTGCCGGTGTCGGCCGCGCCAGTGCCGA
GGCCTTCGCCAGAGCCGGCTACCGCGTCGCGTTGATCGCGCGCGGCGAGCAGGGCCTGAGCGACACCCAGGCGCAGCTCG
AAGCGCTGGGAGCCCGTGTGCTGGCGATCGCCGCCGATGTCGCCGACGCCCCAGCCTTGGAAGCGGCCGCCACGCGCGTC
GAGGCCGAGCTGGGGCCGATCGACGTCTGGGTAAACGCGGCGATGGCCACGGTGTTCGGCCCGTTCTCGGCACTGACCCC
CGAAGAAATCCGCCGCGTCACCGAGGTGACCTACCTGGGCAGCGTGCACGGCACCCTGACCGCCCTGCGCCACATGCGCC
CACGCAACCGCGGCACCATCGTGCAGGTCGGCTCGGCGCTGAGCTATCGCGCGATTCCGCTGCAGTCGGCCTACTGCGGG
GCCAAGTTCGCCATCCGCGGCTTCATCGACTCGCTGCGCTGCGAACTGATTCACGACCGCAGCGGCATTCGCTTGAGCAT
GGTGCAACTGCCGGCGCACAACACGCCGCAGTTCGACTGGGCACGCAACAAGGTCGGCTGGCGTGCACAGCCGGTGCCGC
CGATTCATACACCCGAGGTCGCCGCCCGTGCCGTTCTGCGTGCGGCCCGGGAAGCGCCAAGGGAATTGTGGGTCGGCACC
GCCAGCCTGAAAGCGATCATCGGCACGCTGTTCATGCCCGGGCTGCTCGACCGCATGCTGGCCCGCCAGGCCTGGGACGG
CCAGCTGATCCCCGAGCGTGAGCCCGAGGGCCGCCCCGACAACCTGTTCGAGCCCGTAGAGGGGCTGCACGCCACCGAGG
GTCGCTTCGGCGACCAGGCGAAACCGCGGGCGATCGCCTTGAGCGCGGCGAGCGTCGGCAAGCTGGCGCTGGGCGCCGGC
GCGCTGCTGGCGCTGGGTGCGGGTTGGGCGCTGGGGCGTCGCGGCCGCTGA

Upstream 100 bases:

>100_bases
TCGATAGCCGAGCGATCCACTGGGGCAAGCGGCGAACTCGGCCGGGCCCGGGCGGGTCGTCTAAGCAGCTGCGGGCCACC
GAAAGCGCCCGTTCATTGCA

Downstream 100 bases:

>100_bases
GCCGGCTCAGCCCTGTGGCGGTCGTGGTGCACGTTTACGGCGGATGTTGATCCAGGAAAGCACGGCCAGCGCCAGCATGG
CGCCGGTCATGTTGTAGTTG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTRGLPMPEPTAVICGATAGVGRASAEAFARAGYRVALIARGEQGLSDTQAQLEALGARVLAIAADVADAPALEAAATRV
EAELGPIDVWVNAAMATVFGPFSALTPEEIRRVTEVTYLGSVHGTLTALRHMRPRNRGTIVQVGSALSYRAIPLQSAYCG
AKFAIRGFIDSLRCELIHDRSGIRLSMVQLPAHNTPQFDWARNKVGWRAQPVPPIHTPEVAARAVLRAAREAPRELWVGT
ASLKAIIGTLFMPGLLDRMLARQAWDGQLIPEREPEGRPDNLFEPVEGLHATEGRFGDQAKPRAIALSAASVGKLALGAG
ALLALGAGWALGRRGR

Sequences:

>Translated_336_residues
MTRGLPMPEPTAVICGATAGVGRASAEAFARAGYRVALIARGEQGLSDTQAQLEALGARVLAIAADVADAPALEAAATRV
EAELGPIDVWVNAAMATVFGPFSALTPEEIRRVTEVTYLGSVHGTLTALRHMRPRNRGTIVQVGSALSYRAIPLQSAYCG
AKFAIRGFIDSLRCELIHDRSGIRLSMVQLPAHNTPQFDWARNKVGWRAQPVPPIHTPEVAARAVLRAAREAPRELWVGT
ASLKAIIGTLFMPGLLDRMLARQAWDGQLIPEREPEGRPDNLFEPVEGLHATEGRFGDQAKPRAIALSAASVGKLALGAG
ALLALGAGWALGRRGR
>Mature_335_residues
TRGLPMPEPTAVICGATAGVGRASAEAFARAGYRVALIARGEQGLSDTQAQLEALGARVLAIAADVADAPALEAAATRVE
AELGPIDVWVNAAMATVFGPFSALTPEEIRRVTEVTYLGSVHGTLTALRHMRPRNRGTIVQVGSALSYRAIPLQSAYCGA
KFAIRGFIDSLRCELIHDRSGIRLSMVQLPAHNTPQFDWARNKVGWRAQPVPPIHTPEVAARAVLRAAREAPRELWVGTA
SLKAIIGTLFMPGLLDRMLARQAWDGQLIPEREPEGRPDNLFEPVEGLHATEGRFGDQAKPRAIALSAASVGKLALGAGA
LLALGAGWALGRRGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=165, Percent_Identity=32.7272727272727, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=29.6482412060301, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7706318, Length=167, Percent_Identity=32.3353293413174, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI20149619, Length=170, Percent_Identity=32.9411764705882, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI210032110, Length=281, Percent_Identity=28.1138790035587, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=31.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI38348362, Length=179, Percent_Identity=31.2849162011173, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI50726952, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI38424085, Length=179, Percent_Identity=31.2849162011173, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788459, Length=221, Percent_Identity=27.6018099547511, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787335, Length=166, Percent_Identity=32.5301204819277, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=220, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082100, Length=186, Percent_Identity=31.1827956989247, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=166, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=226, Percent_Identity=28.7610619469027, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=220, Percent_Identity=29.0909090909091, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=281, Percent_Identity=25.9786476868327, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=225, Percent_Identity=28, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21358495, Length=183, Percent_Identity=31.6939890710383, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=28.3132530120482, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356301, Length=267, Percent_Identity=23.9700374531835, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=217, Percent_Identity=26.2672811059908, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35732; Mature: 35600

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGLPMPEPTAVICGATAGVGRASAEAFARAGYRVALIARGEQGLSDTQAQLEALGARV
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LAIAADVADAPALEAAATRVEAELGPIDVWVNAAMATVFGPFSALTPEEIRRVTEVTYLG
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
SVHGTLTALRHMRPRNRGTIVQVGSALSYRAIPLQSAYCGAKFAIRGFIDSLRCELIHDR
CHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCHHCCHHHHHHHHHHHHHHHHHCCC
SGIRLSMVQLPAHNTPQFDWARNKVGWRAQPVPPIHTPEVAARAVLRAAREAPRELWVGT
CCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCH
ASLKAIIGTLFMPGLLDRMLARQAWDGQLIPEREPEGRPDNLFEPVEGLHATEGRFGDQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
KPRAIALSAASVGKLALGAGALLALGAGWALGRRGR
CCCEEEEEHHHHCHHHHCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRGLPMPEPTAVICGATAGVGRASAEAFARAGYRVALIARGEQGLSDTQAQLEALGARV
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LAIAADVADAPALEAAATRVEAELGPIDVWVNAAMATVFGPFSALTPEEIRRVTEVTYLG
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
SVHGTLTALRHMRPRNRGTIVQVGSALSYRAIPLQSAYCGAKFAIRGFIDSLRCELIHDR
CHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCHHCCHHHHHHHHHHHHHHHHHCCC
SGIRLSMVQLPAHNTPQFDWARNKVGWRAQPVPPIHTPEVAARAVLRAAREAPRELWVGT
CCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCH
ASLKAIIGTLFMPGLLDRMLARQAWDGQLIPEREPEGRPDNLFEPVEGLHATEGRFGDQA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCC
KPRAIALSAASVGKLALGAGALLALGAGWALGRRGR
CCCEEEEEHHHHCHHHHCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]