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The map label for this gene is dhbF [H]

Identifier: 145301198

GI number: 145301198

Start: 4686032

End: 4688200

Strand: Direct

Name: dhbF [H]

Synonym: ASA_4376

Alternate gene names: 145301198

Gene position: 4686032-4688200 (Clockwise)

Preceding gene: 145301189

Following gene: 145301201

Centisome position: 99.65

GC content: 52.88

Gene sequence:

>2169_bases
TTGCCACTATGTTACTCCGAGGTATTGCCCGAAATACCTGTGAGCACTCATGAAGAAAATATCTGGTTGTTGCAACAACA
GCATCCGGAGCAAGTCATCAAGCACCTGGAAGTCTGGCGGCTGGATGACAATGTCGATATTTCATTGCTCACTCTGACTA
TTCAGTCATTAATAACGGCCTTGCCGGATTTGAATTCCCGCTATCTCTTCAGTGATGAAGGAGACCTTTATAAATACAGG
GTTGATGGCTGGTATCCCTGTCTGGAATTTATCCGGTTGTCTTCGGGGGACCTCGATACCACCCTTGGCTCCCTTCATAC
GTCGCCCTGGGATTCTGCCAGTCAGCCGCCGTTCAAGGCATTCATTATCCATGTAGAACAGTGTGTTATGTTCGCATTGA
TGTCTCATCCCATACTGGGGGAAGCGTGTTGTCTGGGCCCGCTGGTGGCCAGATTGCGTGATGAGTACGGCGCCCTTGCT
CCGCATCTGCCTTCTCTGGAAATGACAAAGCTATCGATAAACTCAGGCGTGTTAGCACCTGAAATTACCAATAACCAGAC
GGAACACACGGAAAGGGACAAGCTGGCGCTTATTTTACTTGATGAGTTTCGTATTGCTTTATCCAGCCCTGAAATGACGC
TTAATGATGACTTCTTTGATTTTGGCGGCCACTCATTGCTGGCTACGCGCATTATTGGCAAGTTACAGAATCGTCATGGT
ATTGAGTGCCGTTTCAATGATTTTTTTGAGTCGCCTTCTGCGGCTGCCCTCGCTAAAAAAGCAGTATTGAATAGCCCGCC
TCAGCAAATACCTTCACTTGTTGTTGAAAATACCAGCCAGCAGGCACCACTCGCGCTGGCACAAGCGTCATTGTGGCGAG
CCTATGCTGCCCATGATTTTGGCACCATCTTCAATCTGCCCTTTGCGCTGTATTTTATTGATGAAGTTGATGAAACGGTT
TTTTTGCAGGCATTTACAGACCTGATAAAACGCCACCCCAGTTTGCGAACGACTTTCCATGTGCAAGACGGTCAGGTATT
CCAGCGTATTATTCCCGTTGAACATCTGGGCCAATATCGGTGGTTCTGGCACAGCGCTGAAAGCGGAGGTGTCTCCCTGG
CCAATGAGGCGACCTATCAATTCGATCTCTCCCGTGAGCTGCCGATCCGTATCCGTTTCATTCGGGATGTGGCGACTGGC
CGTCAGCACCTCTCATTCCTGGTTCATCACATGGTGGTGGATGAGTGGTCCATCAATCTCATGATGGAGGATCTCGCCAG
CGCTTATCTTGCCCGTGCGGCAGATCAGGCGCCGGTATGGGCCACGCCAGCGCTCGATTTTCACGGATTTGCACGGCAGC
AGGCAGAGCAGGGCATCAATCCCCGGCACCTGGCGTACTGGACCCGGATGTTGCAAGGTGCTGCCGACGAGCGGCGAAAG
CAGCGGCTATGTGCTCCGTCCGAGGGCCAGGGTTCTATCGCGGCGCAGTGGCTGGAGCTCAAGCTCGAGCAGGGGAGTCT
CGACAGTTTGTATGCCTTCGCCAGAGGCCATGACTCTTCGCTCTTCAATCTGGTGTACACGGCGATTGCGGTATCCCTGC
ACAAGCTGGATGACCTGAACGAGATCGTCATAGGGACCTCGGCATCCGGACGTACCGATCCGGCATTCTTTGATACAGTG
GGTTACTTCACCACCATGGTGGCGCACAGGGTCGAGTTCGATGAGCAGGAGTCTTTCGGCAGTCTGTTGAGGACGGTTAC
ACATACCATCAATGACTCCATGTCCTACGCAGACATCCCGCTGGAGCAGATCCAGCAAGGACTTGGCATGACGGCGGCAG
AGGGTCTCCTGTTCGATGTCTATGTCCAGATTCACGCCAAGAATGCCTTGAACGGGCGCTTGCCTACCCCTGCCGGTGAG
GGGATCCGCTACCGACAGATTGATCCTGACAAAACGGAGTCCATGTTCGGGTTGCAGTTCGAGATCATGGAGGATGTGCT
GGAAGGGGAGCGCAGATTGCGGCTGGTGATCACCTATAGCGCCGAACGCTACAGCAGGGATTGGGTCGAAGCCCTTTGCG
TTGTGCTGAACCGGCTGTTCGGTCTGATGACAAGTACCGGTACGAGTGCATGTCGACTGGCTGATCTGGCACTGCAAAAG
GAGGCATAA

Upstream 100 bases:

>100_bases
TCACTGACTCTGACAGCAGGGGAGCTATCTCAGTGGTTTTTGACAGAAAAACCGGCATAACCCAATGGTCATTATTCACA
ATTCAGCAAGGAGGCCACTC

Downstream 100 bases:

>100_bases
ACAGTGTTCTGCCCCCTGTCAGCCGACAGGGGGCAGAACACAAGGCTAGGAGGTTGGCAGCCCGTAGTGCTGGAAGGTGG
AGGTTCGGGGCAGGCGATAC

Product: non-ribosomal peptide synthetase module

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 721

Protein sequence:

>722_residues
MPLCYSEVLPEIPVSTHEENIWLLQQQHPEQVIKHLEVWRLDDNVDISLLTLTIQSLITALPDLNSRYLFSDEGDLYKYR
VDGWYPCLEFIRLSSGDLDTTLGSLHTSPWDSASQPPFKAFIIHVEQCVMFALMSHPILGEACCLGPLVARLRDEYGALA
PHLPSLEMTKLSINSGVLAPEITNNQTEHTERDKLALILLDEFRIALSSPEMTLNDDFFDFGGHSLLATRIIGKLQNRHG
IECRFNDFFESPSAAALAKKAVLNSPPQQIPSLVVENTSQQAPLALAQASLWRAYAAHDFGTIFNLPFALYFIDEVDETV
FLQAFTDLIKRHPSLRTTFHVQDGQVFQRIIPVEHLGQYRWFWHSAESGGVSLANEATYQFDLSRELPIRIRFIRDVATG
RQHLSFLVHHMVVDEWSINLMMEDLASAYLARAADQAPVWATPALDFHGFARQQAEQGINPRHLAYWTRMLQGAADERRK
QRLCAPSEGQGSIAAQWLELKLEQGSLDSLYAFARGHDSSLFNLVYTAIAVSLHKLDDLNEIVIGTSASGRTDPAFFDTV
GYFTTMVAHRVEFDEQESFGSLLRTVTHTINDSMSYADIPLEQIQQGLGMTAAEGLLFDVYVQIHAKNALNGRLPTPAGE
GIRYRQIDPDKTESMFGLQFEIMEDVLEGERRLRLVITYSAERYSRDWVEALCVVLNRLFGLMTSTGTSACRLADLALQK
EA

Sequences:

>Translated_722_residues
MPLCYSEVLPEIPVSTHEENIWLLQQQHPEQVIKHLEVWRLDDNVDISLLTLTIQSLITALPDLNSRYLFSDEGDLYKYR
VDGWYPCLEFIRLSSGDLDTTLGSLHTSPWDSASQPPFKAFIIHVEQCVMFALMSHPILGEACCLGPLVARLRDEYGALA
PHLPSLEMTKLSINSGVLAPEITNNQTEHTERDKLALILLDEFRIALSSPEMTLNDDFFDFGGHSLLATRIIGKLQNRHG
IECRFNDFFESPSAAALAKKAVLNSPPQQIPSLVVENTSQQAPLALAQASLWRAYAAHDFGTIFNLPFALYFIDEVDETV
FLQAFTDLIKRHPSLRTTFHVQDGQVFQRIIPVEHLGQYRWFWHSAESGGVSLANEATYQFDLSRELPIRIRFIRDVATG
RQHLSFLVHHMVVDEWSINLMMEDLASAYLARAADQAPVWATPALDFHGFARQQAEQGINPRHLAYWTRMLQGAADERRK
QRLCAPSEGQGSIAAQWLELKLEQGSLDSLYAFARGHDSSLFNLVYTAIAVSLHKLDDLNEIVIGTSASGRTDPAFFDTV
GYFTTMVAHRVEFDEQESFGSLLRTVTHTINDSMSYADIPLEQIQQGLGMTAAEGLLFDVYVQIHAKNALNGRLPTPAGE
GIRYRQIDPDKTESMFGLQFEIMEDVLEGERRLRLVITYSAERYSRDWVEALCVVLNRLFGLMTSTGTSACRLADLALQK
EA
>Mature_721_residues
PLCYSEVLPEIPVSTHEENIWLLQQQHPEQVIKHLEVWRLDDNVDISLLTLTIQSLITALPDLNSRYLFSDEGDLYKYRV
DGWYPCLEFIRLSSGDLDTTLGSLHTSPWDSASQPPFKAFIIHVEQCVMFALMSHPILGEACCLGPLVARLRDEYGALAP
HLPSLEMTKLSINSGVLAPEITNNQTEHTERDKLALILLDEFRIALSSPEMTLNDDFFDFGGHSLLATRIIGKLQNRHGI
ECRFNDFFESPSAAALAKKAVLNSPPQQIPSLVVENTSQQAPLALAQASLWRAYAAHDFGTIFNLPFALYFIDEVDETVF
LQAFTDLIKRHPSLRTTFHVQDGQVFQRIIPVEHLGQYRWFWHSAESGGVSLANEATYQFDLSRELPIRIRFIRDVATGR
QHLSFLVHHMVVDEWSINLMMEDLASAYLARAADQAPVWATPALDFHGFARQQAEQGINPRHLAYWTRMLQGAADERRKQ
RLCAPSEGQGSIAAQWLELKLEQGSLDSLYAFARGHDSSLFNLVYTAIAVSLHKLDDLNEIVIGTSASGRTDPAFFDTVG
YFTTMVAHRVEFDEQESFGSLLRTVTHTINDSMSYADIPLEQIQQGLGMTAAEGLLFDVYVQIHAKNALNGRLPTPAGEG
IRYRQIDPDKTESMFGLQFEIMEDVLEGERRLRLVITYSAERYSRDWVEALCVVLNRLFGLMTSTGTSACRLADLALQKE
A

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550940, Length=401, Percent_Identity=21.4463840399002, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 81321; Mature: 81190

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLCYSEVLPEIPVSTHEENIWLLQQQHPEQVIKHLEVWRLDDNVDISLLTLTIQSLITA
CCCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHH
LPDLNSRYLFSDEGDLYKYRVDGWYPCLEFIRLSSGDLDTTLGSLHTSPWDSASQPPFKA
CCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHH
FIIHVEQCVMFALMSHPILGEACCLGPLVARLRDEYGALAPHLPSLEMTKLSINSGVLAP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EITNNQTEHTERDKLALILLDEFRIALSSPEMTLNDDFFDFGGHSLLATRIIGKLQNRHG
CCCCCCCCCCCCCCEEEEEEECHHHEECCCCCEECCCCHHCCCHHHHHHHHHHHHHCCCC
IECRFNDFFESPSAAALAKKAVLNSPPQQIPSLVVENTSQQAPLALAQASLWRAYAAHDF
CEEEEHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GTIFNLPFALYFIDEVDETVFLQAFTDLIKRHPSLRTTFHVQDGQVFQRIIPVEHLGQYR
HHHHHCCCCEEEHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHCCCEE
WFWHSAESGGVSLANEATYQFDLSRELPIRIRFIRDVATGRQHLSFLVHHMVVDEWSINL
EEEECCCCCCEEECCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMEDLASAYLARAADQAPVWATPALDFHGFARQQAEQGINPRHLAYWTRMLQGAADERRK
HHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
QRLCAPSEGQGSIAAQWLELKLEQGSLDSLYAFARGHDSSLFNLVYTAIAVSLHKLDDLN
HHCCCCCCCCCHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
EIVIGTSASGRTDPAFFDTVGYFTTMVAHRVEFDEQESFGSLLRTVTHTINDSMSYADIP
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
LEQIQQGLGMTAAEGLLFDVYVQIHAKNALNGRLPTPAGEGIRYRQIDPDKTESMFGLQF
HHHHHHCCCCCHHCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCHHHHCHHH
EIMEDVLEGERRLRLVITYSAERYSRDWVEALCVVLNRLFGLMTSTGTSACRLADLALQK
HHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
EA
CC
>Mature Secondary Structure 
PLCYSEVLPEIPVSTHEENIWLLQQQHPEQVIKHLEVWRLDDNVDISLLTLTIQSLITA
CCCHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHH
LPDLNSRYLFSDEGDLYKYRVDGWYPCLEFIRLSSGDLDTTLGSLHTSPWDSASQPPFKA
CCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHH
FIIHVEQCVMFALMSHPILGEACCLGPLVARLRDEYGALAPHLPSLEMTKLSINSGVLAP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EITNNQTEHTERDKLALILLDEFRIALSSPEMTLNDDFFDFGGHSLLATRIIGKLQNRHG
CCCCCCCCCCCCCCEEEEEEECHHHEECCCCCEECCCCHHCCCHHHHHHHHHHHHHCCCC
IECRFNDFFESPSAAALAKKAVLNSPPQQIPSLVVENTSQQAPLALAQASLWRAYAAHDF
CEEEEHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GTIFNLPFALYFIDEVDETVFLQAFTDLIKRHPSLRTTFHVQDGQVFQRIIPVEHLGQYR
HHHHHCCCCEEEHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHCCCEE
WFWHSAESGGVSLANEATYQFDLSRELPIRIRFIRDVATGRQHLSFLVHHMVVDEWSINL
EEEECCCCCCEEECCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMEDLASAYLARAADQAPVWATPALDFHGFARQQAEQGINPRHLAYWTRMLQGAADERRK
HHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
QRLCAPSEGQGSIAAQWLELKLEQGSLDSLYAFARGHDSSLFNLVYTAIAVSLHKLDDLN
HHCCCCCCCCCHHHHHHHHHEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
EIVIGTSASGRTDPAFFDTVGYFTTMVAHRVEFDEQESFGSLLRTVTHTINDSMSYADIP
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
LEQIQQGLGMTAAEGLLFDVYVQIHAKNALNGRLPTPAGEGIRYRQIDPDKTESMFGLQF
HHHHHHCCCCCHHCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCHHHHCHHH
EIMEDVLEGERRLRLVITYSAERYSRDWVEALCVVLNRLFGLMTSTGTSACRLADLALQK
HHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
EA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]