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The map label for this gene is trkH [H]

Identifier: 145300990

GI number: 145300990

Start: 4434938

End: 4436380

Strand: Direct

Name: trkH [H]

Synonym: ASA_4144

Alternate gene names: 145300990

Gene position: 4434938-4436380 (Clockwise)

Preceding gene: 145300989

Following gene: 145300993

Centisome position: 94.31

GC content: 59.18

Gene sequence:

>1443_bases
ATGATCAAGCTGCGTCCTATCATCTTCACTCTGGGGCTGGTGCTCTCCAAGCTGGCCCTGTTTATGTGGTTGCCCACCCT
GCTTGCCCTGTTCACCGGCTCGGAGGGATTTGTCGAGTTCCTCAAATCCGTGCTGATCACCCATGGTGCTGCTTTGCTCT
GCCTCCACTACGGCCGCAAGGCGGCGTTTCACCTCGGCGTGCGTGAGATGTTCCTGCTCACCACCTCTGTCTGGGTCGTG
GCCTGCATCTTCGGGGCGTTGCCTTTCGTCTTCATCACCCACATCGGCTTTGCCGATGCCTATTTCGAGACAATGTCAGG
GGTCACCACCACGGGATCCACAGTGCTCTCGGGGCTGGACGGCATGGCACACAGCATACTGCTGTGGCGTTCTACCCTGC
AGTGGCTGGGGGGCGTGGGCTTTATCGTGATGGCGGTGGCGGTACTGCCCTACCTCAACGTAGGCGGCATGAAATTGTTC
CAGACCGAGAGCTCGGATTGGTCTGACAAGAGTGCCCCCCGCGCCAAGACGGTGGCCAACAACATAGTGGTGGTCTATCT
GGTGCTCTCCATGTGTTGCTTCCTCGCCTACTGGGTGAGCGGCATGACGCTGTTCGAGGCGGTCAACCACGCCATGACCA
CGCTCAGTACCGGGGGGTATTCCACCTCGGACCAATCCATGTCCCACTTTTCCCATTCGGCGCACTGGATAGGTACCCTC
TTCATGTTTCTCGGGGGGCTGCCCTTCCTGCTCTATGTGCAGAGCCTGAGTCGCCGTGACAACAGCTTGCTCAAGGATGC
TCAGGTGCAGGGCTTCTTCTGGCTGGTAGTCTGGGTCACAGTCGTCGTCACATTTTATCTGTGGGTCAGAGATATCTACG
GCTTTATGGATGCCCTGCGCATCAGCAGCTTCAATATCGTCTCCGTGCTCACCACTACGGGGTATGGCCTCGGCGACTTC
GGCACCTGGGGACCCCTCACCAGCATCATCTTCATCATCTTGCTGGCACTGGGCGCCTGTTCCGGCTCCACTGCCGGCGG
TCTCAAGATTTTCCGGGTGCAGGTAGCATTCGCCCTGTTCAAAAAGCAGATGCGCCAGCTGATGCATCCCTCAGCTGTCT
TCCCGCAGAAGTACAACGGCCGCCCAGTCAGCGATGCCATCATTCGATCCATGATCTCCTTCGTGCTGGCCTACTTCGCC
ATCATATTGCTGATCGCCGCCCTGCTCGCCGCCATCGGCCTGGACCCCCTGACTGCCATCTCGGGTTCCATCACTGCGGT
TGCAAACGTGGGCCCCGGCATGGGCCCCGTCATAGGACCCAGCACCAACTTCGCCACCCTGCCGGACTCTGCCAAGTGGA
TATTGTCGTTCGGCATGCTGCTGGGGCGCCTCGAGATCCTGACCGTGGCCGTGATCTTCTTCCCCTCGTTCTGGAAGCAG
TAA

Upstream 100 bases:

>100_bases
TGTAATCTGCCATGCATCCAGCCAGCACAACCCAGACCCGGCACTGCCTCCCAATGGAAGTATCCGGGTCTCTTGTCACT
CAACGACCAGGTTATCCTGC

Downstream 100 bases:

>100_bases
TTCCTGCCAGGATAGCGATAACACAGAAAACAGAAGGGCAGCCTTGCGGCTGCCCTTCTCCATCTCATATGCTGGCAAGG
CTCGGCGCTATTCGGCCGGG

Product: potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MIKLRPIIFTLGLVLSKLALFMWLPTLLALFTGSEGFVEFLKSVLITHGAALLCLHYGRKAAFHLGVREMFLLTTSVWVV
ACIFGALPFVFITHIGFADAYFETMSGVTTTGSTVLSGLDGMAHSILLWRSTLQWLGGVGFIVMAVAVLPYLNVGGMKLF
QTESSDWSDKSAPRAKTVANNIVVVYLVLSMCCFLAYWVSGMTLFEAVNHAMTTLSTGGYSTSDQSMSHFSHSAHWIGTL
FMFLGGLPFLLYVQSLSRRDNSLLKDAQVQGFFWLVVWVTVVVTFYLWVRDIYGFMDALRISSFNIVSVLTTTGYGLGDF
GTWGPLTSIIFIILLALGACSGSTAGGLKIFRVQVAFALFKKQMRQLMHPSAVFPQKYNGRPVSDAIIRSMISFVLAYFA
IILLIAALLAAIGLDPLTAISGSITAVANVGPGMGPVIGPSTNFATLPDSAKWILSFGMLLGRLEILTVAVIFFPSFWKQ

Sequences:

>Translated_480_residues
MIKLRPIIFTLGLVLSKLALFMWLPTLLALFTGSEGFVEFLKSVLITHGAALLCLHYGRKAAFHLGVREMFLLTTSVWVV
ACIFGALPFVFITHIGFADAYFETMSGVTTTGSTVLSGLDGMAHSILLWRSTLQWLGGVGFIVMAVAVLPYLNVGGMKLF
QTESSDWSDKSAPRAKTVANNIVVVYLVLSMCCFLAYWVSGMTLFEAVNHAMTTLSTGGYSTSDQSMSHFSHSAHWIGTL
FMFLGGLPFLLYVQSLSRRDNSLLKDAQVQGFFWLVVWVTVVVTFYLWVRDIYGFMDALRISSFNIVSVLTTTGYGLGDF
GTWGPLTSIIFIILLALGACSGSTAGGLKIFRVQVAFALFKKQMRQLMHPSAVFPQKYNGRPVSDAIIRSMISFVLAYFA
IILLIAALLAAIGLDPLTAISGSITAVANVGPGMGPVIGPSTNFATLPDSAKWILSFGMLLGRLEILTVAVIFFPSFWKQ
>Mature_480_residues
MIKLRPIIFTLGLVLSKLALFMWLPTLLALFTGSEGFVEFLKSVLITHGAALLCLHYGRKAAFHLGVREMFLLTTSVWVV
ACIFGALPFVFITHIGFADAYFETMSGVTTTGSTVLSGLDGMAHSILLWRSTLQWLGGVGFIVMAVAVLPYLNVGGMKLF
QTESSDWSDKSAPRAKTVANNIVVVYLVLSMCCFLAYWVSGMTLFEAVNHAMTTLSTGGYSTSDQSMSHFSHSAHWIGTL
FMFLGGLPFLLYVQSLSRRDNSLLKDAQVQGFFWLVVWVTVVVTFYLWVRDIYGFMDALRISSFNIVSVLTTTGYGLGDF
GTWGPLTSIIFIILLALGACSGSTAGGLKIFRVQVAFALFKKQMRQLMHPSAVFPQKYNGRPVSDAIIRSMISFVLAYFA
IILLIAALLAAIGLDPLTAISGSITAVANVGPGMGPVIGPSTNFATLPDSAKWILSFGMLLGRLEILTVAVIFFPSFWKQ

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=486, Percent_Identity=32.9218106995885, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1787626, Length=429, Percent_Identity=32.4009324009324, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52338; Mature: 52338

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]