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The map label for this gene is trkA [H]

Identifier: 145300989

GI number: 145300989

Start: 4433466

End: 4434842

Strand: Direct

Name: trkA [H]

Synonym: ASA_4143

Alternate gene names: 145300989

Gene position: 4433466-4434842 (Clockwise)

Preceding gene: 145300988

Following gene: 145300990

Centisome position: 94.28

GC content: 61.0

Gene sequence:

>1377_bases
ATGAAGATCATCATTCTGGGCGCAGGCCAGGTCGGTGGCACCCTGGCCGAAAACCTGGCCGGAGAGAACAACGACATCAC
CATAGTCGATACCGACAGCGACCGTCTGCGGGAGCTGCAGGACAAGTTCGACCTGCGGGTGGTGAATGGTCACGGCGCCC
ACCCCAGGGTACTGCGCGAGGCGGGTGCACAGGATGCGGACATGCTGGTGGCGGTCACCAACAGCGACGAAACCAACATG
ATCGCCTGCCAGGTGGCCTACTCCCTGTTCAATACCCCGAACAAGGTGGCGCGCATTCGCTCCCCGGCTTATCTGACCGA
GCGGGACCGGCTGTTTTTACCGGAATCCGTGCCGGTGGATCACCTGATAGCGCCAGAACAGCTGGTCACCGACTATGTTC
GCCGACTGATCGAATATCCCGGCGCCTTGCAAGTGGTGGACTTTGCCGGTGGCAAGGTGGGTCTGGTGGCAGTCAAGGCC
TACTATGGTGGCCCCCTGGTGGGCAATGCTCTCTCCACTCTGCGGGATCACATGCCCAACATAGAGACCCGGGTAGCGGC
CATCTTCCGCCAGGGCCGCTCCATCCGTCCGCAAGGCACCACCATCATAGAAGCGGATGACGAAGTGTTCTTCGTCGCTG
CCGCCGGTCATATTCGGGCCGTCATGTCGGAGCTCCAGCGGCTCGAGAGCCCTTATCGCCGCATCATGATAGTCGGGGGT
GGCAACATAGGGGCCGGTCTCGCCCGTCAGCTGGAGAAGCGCTACAGCGTCAAGCTCATAGAGCGTAACCAGAAACGGGC
CGAGCAACTCTCGGAACAGTTGGAGAACACCATCGTCTTCTGTGGTGATGCAGCGGATCAGGAGTTGCTGGCCGAGGAGC
ACATCGATCAGATCGATGTCTTCATCGCGGTCACCAACGAGGATGAGGCCAACATAATGTCGGCCCTGCTCGCCAAGAAG
ATGGGTGCCAAGAAGACAATGGTGCTTATCCAGCGCAGCGCCTACGTGGATCTGGTGCAGGGCGGCTCCATCGACATCGC
CATCTCGCCACAGCAGGCCACCATTTCGGCCCTGCTGACCCACGTGCGCCGGGCCGATATTGCCAACGTCTACAGCCTGC
GCCGCGGGGCGGCCGAAGCCATCGAGGCCATAGCCCACGGTGACGAGAACACCTCCAAGGTGGTGGGCAAGACGGTGGGC
GAGCTCAAGCTGCCGCCCGGCACCACCATAGGCGCCGTTGTCCGCGGTGATGAGGTGCTGATCGCCCACGATCGCACCCA
GATCCAGCAGGATGACCATGTGGTGATGTTCCTGGTGGACAAGAAGTACATACCGGAAGTGGAACGGCTATTCCAGCCAA
GTCCCTTCTTCCTGTAA

Upstream 100 bases:

>100_bases
ACATCGAGCACGTTTTCCCTATGAAAATCACCATGTTGATGACTGATCCCTGCCATATTGTCAGCGGTAACAACCCATCC
TCGTCCCAAGAGGGGTCCCA

Downstream 100 bases:

>100_bases
TCTGCCATGCATCCAGCCAGCACAACCCAGACCCGGCACTGCCTCCCAATGGAAGTATCCGGGTCTCTTGTCACTCAACG
ACCAGGTTATCCTGCATGAT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGGTLAENLAGENNDITIVDTDSDRLRELQDKFDLRVVNGHGAHPRVLREAGAQDADMLVAVTNSDETNM
IACQVAYSLFNTPNKVARIRSPAYLTERDRLFLPESVPVDHLIAPEQLVTDYVRRLIEYPGALQVVDFAGGKVGLVAVKA
YYGGPLVGNALSTLRDHMPNIETRVAAIFRQGRSIRPQGTTIIEADDEVFFVAAAGHIRAVMSELQRLESPYRRIMIVGG
GNIGAGLARQLEKRYSVKLIERNQKRAEQLSEQLENTIVFCGDAADQELLAEEHIDQIDVFIAVTNEDEANIMSALLAKK
MGAKKTMVLIQRSAYVDLVQGGSIDIAISPQQATISALLTHVRRADIANVYSLRRGAAEAIEAIAHGDENTSKVVGKTVG
ELKLPPGTTIGAVVRGDEVLIAHDRTQIQQDDHVVMFLVDKKYIPEVERLFQPSPFFL

Sequences:

>Translated_458_residues
MKIIILGAGQVGGTLAENLAGENNDITIVDTDSDRLRELQDKFDLRVVNGHGAHPRVLREAGAQDADMLVAVTNSDETNM
IACQVAYSLFNTPNKVARIRSPAYLTERDRLFLPESVPVDHLIAPEQLVTDYVRRLIEYPGALQVVDFAGGKVGLVAVKA
YYGGPLVGNALSTLRDHMPNIETRVAAIFRQGRSIRPQGTTIIEADDEVFFVAAAGHIRAVMSELQRLESPYRRIMIVGG
GNIGAGLARQLEKRYSVKLIERNQKRAEQLSEQLENTIVFCGDAADQELLAEEHIDQIDVFIAVTNEDEANIMSALLAKK
MGAKKTMVLIQRSAYVDLVQGGSIDIAISPQQATISALLTHVRRADIANVYSLRRGAAEAIEAIAHGDENTSKVVGKTVG
ELKLPPGTTIGAVVRGDEVLIAHDRTQIQQDDHVVMFLVDKKYIPEVERLFQPSPFFL
>Mature_458_residues
MKIIILGAGQVGGTLAENLAGENNDITIVDTDSDRLRELQDKFDLRVVNGHGAHPRVLREAGAQDADMLVAVTNSDETNM
IACQVAYSLFNTPNKVARIRSPAYLTERDRLFLPESVPVDHLIAPEQLVTDYVRRLIEYPGALQVVDFAGGKVGLVAVKA
YYGGPLVGNALSTLRDHMPNIETRVAAIFRQGRSIRPQGTTIIEADDEVFFVAAAGHIRAVMSELQRLESPYRRIMIVGG
GNIGAGLARQLEKRYSVKLIERNQKRAEQLSEQLENTIVFCGDAADQELLAEEHIDQIDVFIAVTNEDEANIMSALLAKK
MGAKKTMVLIQRSAYVDLVQGGSIDIAISPQQATISALLTHVRRADIANVYSLRRGAAEAIEAIAHGDENTSKVVGKTVG
ELKLPPGTTIGAVVRGDEVLIAHDRTQIQQDDHVVMFLVDKKYIPEVERLFQPSPFFL

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=78.6026200873362, Blast_Score=754, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50177; Mature: 50177

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAENLAGENNDITIVDTDSDRLRELQDKFDLRVVNGHGAHPRVLRE
CEEEEEECCCCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEECCCCCCHHHHHH
AGAQDADMLVAVTNSDETNMIACQVAYSLFNTPNKVARIRSPAYLTERDRLFLPESVPVD
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHCCCCEECCCCCEECCCCCCHH
HLIAPEQLVTDYVRRLIEYPGALQVVDFAGGKVGLVAVKAYYGGPLVGNALSTLRDHMPN
HCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHCCC
IETRVAAIFRQGRSIRPQGTTIIEADDEVFFVAAAGHIRAVMSELQRLESPYRRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEC
GNIGAGLARQLEKRYSVKLIERNQKRAEQLSEQLENTIVFCGDAADQELLAEEHIDQIDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHCCCEEEE
FIAVTNEDEANIMSALLAKKMGAKKTMVLIQRSAYVDLVQGGSIDIAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIANVYSLRRGAAEAIEAIAHGDENTSKVVGKTVGELKLPPGTTIGAVVRGDEVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCEEEEEECCEEE
IAHDRTQIQQDDHVVMFLVDKKYIPEVERLFQPSPFFL
EEECCHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAENLAGENNDITIVDTDSDRLRELQDKFDLRVVNGHGAHPRVLRE
CEEEEEECCCCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEECCCCCCHHHHHH
AGAQDADMLVAVTNSDETNMIACQVAYSLFNTPNKVARIRSPAYLTERDRLFLPESVPVD
CCCCCCCEEEEEECCCCCCEEHHHHHHHHHCCCHHHHHHCCCCEECCCCCEECCCCCCHH
HLIAPEQLVTDYVRRLIEYPGALQVVDFAGGKVGLVAVKAYYGGPLVGNALSTLRDHMPN
HCCCHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHCCC
IETRVAAIFRQGRSIRPQGTTIIEADDEVFFVAAAGHIRAVMSELQRLESPYRRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEEC
GNIGAGLARQLEKRYSVKLIERNQKRAEQLSEQLENTIVFCGDAADQELLAEEHIDQIDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHCCCEEEE
FIAVTNEDEANIMSALLAKKMGAKKTMVLIQRSAYVDLVQGGSIDIAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIANVYSLRRGAAEAIEAIAHGDENTSKVVGKTVGELKLPPGTTIGAVVRGDEVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCEEEEEECCEEE
IAHDRTQIQQDDHVVMFLVDKKYIPEVERLFQPSPFFL
EEECCHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]