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The map label for this gene is recG [H]

Identifier: 145300961

GI number: 145300961

Start: 4402485

End: 4404557

Strand: Direct

Name: recG [H]

Synonym: ASA_4113

Alternate gene names: 145300961

Gene position: 4402485-4404557 (Clockwise)

Preceding gene: 145300960

Following gene: 145300962

Centisome position: 93.62

GC content: 65.03

Gene sequence:

>2073_bases
TTGATGAAATTGGATAAAATCTCCCTCGACAGCCTCAAGGGCGTCGGCAGCAAGATGCAGGAAAAACTCGAGCGACTGGG
GCTGGCCACGGTACAGGATCTGCTGTTCCACCTCCCCCTTCGTTACGAGGATCGTACCCAGGTGTGGCCCATCGGCGATC
TGCCGCCCGGGCTGCACGGCGCCGTCGAGGGCGAAATCCAGGACACTCAATTGGTGATGGGGCGCCGCCGCATGCTGGTC
TGCCGCATCAGTGACGGCACCGGTACTCTGACCCTTCGCTTCTTCAACTTCACCGCAGCCCAGAAAAACAGCCTGGGGCA
GGGCAGGTTGATCCGCTGCTTCGGCGAGGTGCGCCCCGGCAAATACGGGCTCGAGATGGCCCACCCCGAGTACAAGCTGC
TCGGTGAAGAACAGGCAGGTCAGACCGAAGAGGCACTCACCCCCGTTTACCCCACCACGGAAGGGCTGCGCCAGCTCACC
CTGCGTAGCCTCACCGATCAGGCGCTGGCTCAACTCGACCTGTACGGGGTGGAGGAGCTGCTGCCTGCAGGCCTCTATCC
CCAGCAGATCGATCTGGCCGCCGCCCTGCGCCTGCTCCATCGCCCGCCCCCCTCGGTGGCGCTGGCCTTGCTGGAGAGCG
GCCAGCACCCGGCCCAGCAACGACTGGTGCTGGAAGAGCTGCTGGCCCATAACCTGTCGGTGCTCAAAGTGCGTGCCCAG
GCGCAAACCCAGCTGGCGCGCGCCCTCAAGCCGGCACCTGCCCTGGTCAAGCAATTGCTGGAAGCGCTGCCGTTCAAACC
GACCGGTGCCCAGAATCGGGTGGTAGCCGAGATCAACCAGGACCTGCAACGCAGCTACCCCATGATGCGCCTGGTGCAGG
GGGACGTGGGCTCCGGCAAGACGCTGGTTGCGGCGCTGGCAGCCCTCCAGGCCATCGGCAACGGCTGCCAGGTGGGGCTG
ATGGCACCGACCGAGTTGCTGGCCGAACAGCATGCCATCAACTTCGCCAACTGGCTGGAGCCGCTCGGTATCGGGGTCGG
CTGGCTGGCGGGCAAGCAGAAAGGGAAGGCGCGGGAAACCCAGCTCGCCGCCATCGCCGATGGCAGCGTCAAGATGGTGG
TGGGCACCCACGCCATCTTCCAGGAGCAGGTGGTGTTCCAACGCCTCGCGCTGGTCATCATCGATGAACAGCACAGATTC
GGGGTGCATCAGCGCCTCGCGCTGCGGGAAAAAGGGGAGCGGGAGGGAGTCCATCCCCATCAGCTCATCATGACTGCCAC
TCCCATACCCCGCACCCTGGCGATGACCGCCTATGCCGATCTCGACACCTCCGTCATCGACGAGCTGCCACCGGGCCGCA
CCCCCATCACCACGGTGGCGCTGCCGGACAGCCGTCGCCCGGATGTGATCGAGCGGGTCAAGCTGGCCTGTGAAGAGGGC
AAGCAGGCCTACTGGGTCTGTACCCTGATCGAAGAGTCCGAGGTGCTGGAGTGCCAGGCCGCCGAGGATACCGCCGCCGA
GCTGCAAAACCAGCTGCCCGGCCTGCATATCGGGCTGGTACACGGCCGGATGCGGCCGGTCGAAAAGCAGCGGGTGATGG
AGGAGTTCAAGGCGGGCATACTGCAGCTGCTGGTCGCCACCACAGTCATAGAGGTGGGGGTGGATGTACCCAACGCCAGC
CTGATGATCATCGAAAACCCGGAGCGGCTCGGGCTGGCCCAGTTGCACCAGCTGCGCGGCCGGGTCGGTCGCGGTTCTGT
GGCCTCTCATTGCGTGCTGCTCTATCATGCTCCCTTGTCCAAGACGGCCCAGAGCCGACTCGGGGTATTGCGGGAGACCA
ACGACGGCTTCCTGATCGCCCAGCGCGATCTCGAGCTGCGCGGCCCGGGGGAACTGCTAGGTACCCGCCAGACCGGGCTG
GCCGATCTCAAAATTGCCGACCTGGTGCGCGACCAGCCACTCATCCCTCAGGTACAGAAGATGGCGCGCTTCCTGATGGA
CAGGCATCCCGCCCATGTTGAACCGCTCATCCGGCGCTGGCTGGGTCTGCGGGATCACTACTCCAACGCCTGA

Upstream 100 bases:

>100_bases
ACCTCTGGCCTGGCGCCAGGTGTCACTGCAACGCGGCTTGCACCGAGACGTCAATAACCCCTATCATTTGGACATATTTA
CAGTGTTTTCGGGCATCTAA

Downstream 100 bases:

>100_bases
GTAGAGCAGAACAAGAAAGAACTAACGTGACACTCAGGCTCCCAATAGATGTGTTGCCACAACACTCAGACCCTGGAGGA
AAGCACCGATGAATTCCTGG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MMKLDKISLDSLKGVGSKMQEKLERLGLATVQDLLFHLPLRYEDRTQVWPIGDLPPGLHGAVEGEIQDTQLVMGRRRMLV
CRISDGTGTLTLRFFNFTAAQKNSLGQGRLIRCFGEVRPGKYGLEMAHPEYKLLGEEQAGQTEEALTPVYPTTEGLRQLT
LRSLTDQALAQLDLYGVEELLPAGLYPQQIDLAAALRLLHRPPPSVALALLESGQHPAQQRLVLEELLAHNLSVLKVRAQ
AQTQLARALKPAPALVKQLLEALPFKPTGAQNRVVAEINQDLQRSYPMMRLVQGDVGSGKTLVAALAALQAIGNGCQVGL
MAPTELLAEQHAINFANWLEPLGIGVGWLAGKQKGKARETQLAAIADGSVKMVVGTHAIFQEQVVFQRLALVIIDEQHRF
GVHQRLALREKGEREGVHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPITTVALPDSRRPDVIERVKLACEEG
KQAYWVCTLIEESEVLECQAAEDTAAELQNQLPGLHIGLVHGRMRPVEKQRVMEEFKAGILQLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHAPLSKTAQSRLGVLRETNDGFLIAQRDLELRGPGELLGTRQTGL
ADLKIADLVRDQPLIPQVQKMARFLMDRHPAHVEPLIRRWLGLRDHYSNA

Sequences:

>Translated_690_residues
MMKLDKISLDSLKGVGSKMQEKLERLGLATVQDLLFHLPLRYEDRTQVWPIGDLPPGLHGAVEGEIQDTQLVMGRRRMLV
CRISDGTGTLTLRFFNFTAAQKNSLGQGRLIRCFGEVRPGKYGLEMAHPEYKLLGEEQAGQTEEALTPVYPTTEGLRQLT
LRSLTDQALAQLDLYGVEELLPAGLYPQQIDLAAALRLLHRPPPSVALALLESGQHPAQQRLVLEELLAHNLSVLKVRAQ
AQTQLARALKPAPALVKQLLEALPFKPTGAQNRVVAEINQDLQRSYPMMRLVQGDVGSGKTLVAALAALQAIGNGCQVGL
MAPTELLAEQHAINFANWLEPLGIGVGWLAGKQKGKARETQLAAIADGSVKMVVGTHAIFQEQVVFQRLALVIIDEQHRF
GVHQRLALREKGEREGVHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPITTVALPDSRRPDVIERVKLACEEG
KQAYWVCTLIEESEVLECQAAEDTAAELQNQLPGLHIGLVHGRMRPVEKQRVMEEFKAGILQLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHAPLSKTAQSRLGVLRETNDGFLIAQRDLELRGPGELLGTRQTGL
ADLKIADLVRDQPLIPQVQKMARFLMDRHPAHVEPLIRRWLGLRDHYSNA
>Mature_690_residues
MMKLDKISLDSLKGVGSKMQEKLERLGLATVQDLLFHLPLRYEDRTQVWPIGDLPPGLHGAVEGEIQDTQLVMGRRRMLV
CRISDGTGTLTLRFFNFTAAQKNSLGQGRLIRCFGEVRPGKYGLEMAHPEYKLLGEEQAGQTEEALTPVYPTTEGLRQLT
LRSLTDQALAQLDLYGVEELLPAGLYPQQIDLAAALRLLHRPPPSVALALLESGQHPAQQRLVLEELLAHNLSVLKVRAQ
AQTQLARALKPAPALVKQLLEALPFKPTGAQNRVVAEINQDLQRSYPMMRLVQGDVGSGKTLVAALAALQAIGNGCQVGL
MAPTELLAEQHAINFANWLEPLGIGVGWLAGKQKGKARETQLAAIADGSVKMVVGTHAIFQEQVVFQRLALVIIDEQHRF
GVHQRLALREKGEREGVHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPITTVALPDSRRPDVIERVKLACEEG
KQAYWVCTLIEESEVLECQAAEDTAAELQNQLPGLHIGLVHGRMRPVEKQRVMEEFKAGILQLLVATTVIEVGVDVPNAS
LMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHAPLSKTAQSRLGVLRETNDGFLIAQRDLELRGPGELLGTRQTGL
ADLKIADLVRDQPLIPQVQKMARFLMDRHPAHVEPLIRRWLGLRDHYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=68.8953488372093, Blast_Score=929, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=411, Percent_Identity=37.2262773722628, Blast_Score=231, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76039; Mature: 76039

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLDKISLDSLKGVGSKMQEKLERLGLATVQDLLFHLPLRYEDRTQVWPIGDLPPGLHG
CCCCCCCCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCC
AVEGEIQDTQLVMGRRRMLVCRISDGTGTLTLRFFNFTAAQKNSLGQGRLIRCFGEVRPG
CCCCCCCHHHHHHCCCEEEEEEEECCCCEEEEEEEEEEHHHCCCCCCCCEEEEECCCCCC
KYGLEMAHPEYKLLGEEQAGQTEEALTPVYPTTEGLRQLTLRSLTDQALAQLDLYGVEEL
CCCCEECCCHHHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LPAGLYPQQIDLAAALRLLHRPPPSVALALLESGQHPAQQRLVLEELLAHNLSVLKVRAQ
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHH
AQTQLARALKPAPALVKQLLEALPFKPTGAQNRVVAEINQDLQRSYPMMRLVQGDVGSGK
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCH
TLVAALAALQAIGNGCQVGLMAPTELLAEQHAINFANWLEPLGIGVGWLAGKQKGKARET
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCCCCCCHHH
QLAAIADGSVKMVVGTHAIFQEQVVFQRLALVIIDEQHRFGVHQRLALREKGEREGVHPH
EEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHCCCCCCCCHH
QLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPITTVALPDSRRPDVIERVKLACEEG
HEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCC
KQAYWVCTLIEESEVLECQAAEDTAAELQNQLPGLHIGLVHGRMRPVEKQRVMEEFKAGI
CCEEEEEEEECCCCHHEEECCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
LQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHAPLS
HHHHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCCHHHCEEEEEECCHH
KTAQSRLGVLRETNDGFLIAQRDLELRGPGELLGTRQTGLADLKIADLVRDQPLIPQVQK
HHHHHHHHHHEECCCCEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHH
MARFLMDRHPAHVEPLIRRWLGLRDHYSNA
HHHHHHHCCCCHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MMKLDKISLDSLKGVGSKMQEKLERLGLATVQDLLFHLPLRYEDRTQVWPIGDLPPGLHG
CCCCCCCCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCC
AVEGEIQDTQLVMGRRRMLVCRISDGTGTLTLRFFNFTAAQKNSLGQGRLIRCFGEVRPG
CCCCCCCHHHHHHCCCEEEEEEEECCCCEEEEEEEEEEHHHCCCCCCCCEEEEECCCCCC
KYGLEMAHPEYKLLGEEQAGQTEEALTPVYPTTEGLRQLTLRSLTDQALAQLDLYGVEEL
CCCCEECCCHHHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LPAGLYPQQIDLAAALRLLHRPPPSVALALLESGQHPAQQRLVLEELLAHNLSVLKVRAQ
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHH
AQTQLARALKPAPALVKQLLEALPFKPTGAQNRVVAEINQDLQRSYPMMRLVQGDVGSGK
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCH
TLVAALAALQAIGNGCQVGLMAPTELLAEQHAINFANWLEPLGIGVGWLAGKQKGKARET
HHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCCCCCCHHH
QLAAIADGSVKMVVGTHAIFQEQVVFQRLALVIIDEQHRFGVHQRLALREKGEREGVHPH
EEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHEECCHHHCCHHHHHHHHHCCCCCCCCHH
QLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPITTVALPDSRRPDVIERVKLACEEG
HEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCC
KQAYWVCTLIEESEVLECQAAEDTAAELQNQLPGLHIGLVHGRMRPVEKQRVMEEFKAGI
CCEEEEEEEECCCCHHEEECCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
LQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGSVASHCVLLYHAPLS
HHHHHHHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCCHHHCEEEEEECCHH
KTAQSRLGVLRETNDGFLIAQRDLELRGPGELLGTRQTGLADLKIADLVRDQPLIPQVQK
HHHHHHHHHHEECCCCEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHH
MARFLMDRHPAHVEPLIRRWLGLRDHYSNA
HHHHHHHCCCCHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]