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The map label for this gene is pssA [H]

Identifier: 145300960

GI number: 145300960

Start: 4400935

End: 4402284

Strand: Direct

Name: pssA [H]

Synonym: ASA_4112

Alternate gene names: 145300960

Gene position: 4400935-4402284 (Clockwise)

Preceding gene: 145300959

Following gene: 145300961

Centisome position: 93.59

GC content: 58.67

Gene sequence:

>1350_bases
ATGCATTCATCGGCACATTATCGACAACTGTTGGCTCGTCTGCCCCAGATCGCTGTCGCCGCAGATCAGTTTCAGGTGCT
CAACAGCGCCAAGGACTTCAAGAGCCGGATCCTTTCGCTTATCGCCAGCGCGACTCGGCGCATCTATCTGGTGGCGCTCT
ATCTGCAAGATGACGAGGCGGGACGGGAAATTCTGTCTGCCCTCTACGCCTCCAAGCAGCGCAACCCGGCCCTGGACATC
AAGTTGTTCGTGGATTTTCACCGTGCCCAACGCGGCCTGATCGGCAAAGGCAAGCAGGGGGGCAATCACCTGATGTATCA
GGAAATGGCCGCCCGCCATGAACACCAGATCGCCATCTACGGCGTGCCGGTCAAGGGACGAGAGCTGCTCGGGGTGCTGC
ACCTCAAGGGCTTCATCTTCGATGACACCCTGCTCTACTCCGGTGCCAGCCTCAACGATATCTACCTGCATCAGCAGGAT
CGCTACCGTTTCGACCGTTATCACCAGATCACCAGCCCAGAGCTGACCCGCTGCATGGTCAACTATGTGGACGATCTCTT
TCTCAAGAGCGAAGCGGTGCAGCGACTCGATCGCAGCGACATTCCCACCGCCAAGCAACTGAAGGGGCCGATCCGCCGCT
TCAAGCACAGCCTGCGCCTGGGCCAGTACCGCTTCGAGAGCATGCCGGTCAACAGCCAGGAGATCGCCATCACTCCGATG
ACGGGGCTAGGCAAGCGGGGCAATCAGCTCAACAAGATGATCCGTACCCTGGTGCGTGCCACCGAGCGGGAGATCTTCAT
CTGCACCCCCTATTTCAACCCGCCCAAGGAGTTGAACAAGGACATCGAAGCCCTGCTCAAGCGCGGCTGCAAGGTGACCA
TAGTGGTGGGCGACAAGACGGCCAACGACTTCTTCATCCCTCCGGAAGAGAAGTTCACCACCATAGGTGGCCTGCCTTAT
CTGTACGAGACCAATCTGCGCAAGTTTGCCGAGCGCAATCAGCATCATATCGATGCCGGCCGTCTCAACCTGATGTTGTG
GTGCTGCGAGCGCAACTCCTACCACCTCAAGGGGATCTTCGTGGATGACGAGTGGGCACTGCTCACCGGCAACAACCTGA
ACCCTCGCGCTTGGGCGCTTGATCTGGAGAACGGCCTGCTGGTGTACGATCGTCGCCATCACCTGCGCGCCCAGTTCAAC
GGGGAGCGGGAGAACATACTCGCCAACACCAAGCGGATCAGCCACTTCGATCAGATAGAGCAGATCAAGGACTACCCGGA
ACAGGTACGCAAGCTGCTGGCCAGGATCCACAGGGTCAGGGCCCATATCCTGCTCAAGCGCATCATCTGA

Upstream 100 bases:

>100_bases
TTTATGACGATTCTTTCTTTGGCTAACAGGTTGAGGTTGCTAGAATCGCCTATCCATCGCTCCGAGTGGAACGCTTAACG
CAGTGATTTCAGGTTTCTCT

Downstream 100 bases:

>100_bases
TCCGGCGTACACGCTGCCCGTCCTCACTCGTTTACACCAGTGCAAAGGCCTGCCGTTTTCGGCAGGCCTTTTTGTCAGGC
TCTGCCATGGTCCGCATCCC

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MHSSAHYRQLLARLPQIAVAADQFQVLNSAKDFKSRILSLIASATRRIYLVALYLQDDEAGREILSALYASKQRNPALDI
KLFVDFHRAQRGLIGKGKQGGNHLMYQEMAARHEHQIAIYGVPVKGRELLGVLHLKGFIFDDTLLYSGASLNDIYLHQQD
RYRFDRYHQITSPELTRCMVNYVDDLFLKSEAVQRLDRSDIPTAKQLKGPIRRFKHSLRLGQYRFESMPVNSQEIAITPM
TGLGKRGNQLNKMIRTLVRATEREIFICTPYFNPPKELNKDIEALLKRGCKVTIVVGDKTANDFFIPPEEKFTTIGGLPY
LYETNLRKFAERNQHHIDAGRLNLMLWCCERNSYHLKGIFVDDEWALLTGNNLNPRAWALDLENGLLVYDRRHHLRAQFN
GERENILANTKRISHFDQIEQIKDYPEQVRKLLARIHRVRAHILLKRII

Sequences:

>Translated_449_residues
MHSSAHYRQLLARLPQIAVAADQFQVLNSAKDFKSRILSLIASATRRIYLVALYLQDDEAGREILSALYASKQRNPALDI
KLFVDFHRAQRGLIGKGKQGGNHLMYQEMAARHEHQIAIYGVPVKGRELLGVLHLKGFIFDDTLLYSGASLNDIYLHQQD
RYRFDRYHQITSPELTRCMVNYVDDLFLKSEAVQRLDRSDIPTAKQLKGPIRRFKHSLRLGQYRFESMPVNSQEIAITPM
TGLGKRGNQLNKMIRTLVRATEREIFICTPYFNPPKELNKDIEALLKRGCKVTIVVGDKTANDFFIPPEEKFTTIGGLPY
LYETNLRKFAERNQHHIDAGRLNLMLWCCERNSYHLKGIFVDDEWALLTGNNLNPRAWALDLENGLLVYDRRHHLRAQFN
GERENILANTKRISHFDQIEQIKDYPEQVRKLLARIHRVRAHILLKRII
>Mature_449_residues
MHSSAHYRQLLARLPQIAVAADQFQVLNSAKDFKSRILSLIASATRRIYLVALYLQDDEAGREILSALYASKQRNPALDI
KLFVDFHRAQRGLIGKGKQGGNHLMYQEMAARHEHQIAIYGVPVKGRELLGVLHLKGFIFDDTLLYSGASLNDIYLHQQD
RYRFDRYHQITSPELTRCMVNYVDDLFLKSEAVQRLDRSDIPTAKQLKGPIRRFKHSLRLGQYRFESMPVNSQEIAITPM
TGLGKRGNQLNKMIRTLVRATEREIFICTPYFNPPKELNKDIEALLKRGCKVTIVVGDKTANDFFIPPEEKFTTIGGLPY
LYETNLRKFAERNQHHIDAGRLNLMLWCCERNSYHLKGIFVDDEWALLTGNNLNPRAWALDLENGLLVYDRRHHLRAQFN
GERENILANTKRISHFDQIEQIKDYPEQVRKLLARIHRVRAHILLKRII

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=424, Percent_Identity=46.9339622641509, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI28572961, Length=439, Percent_Identity=23.4624145785877, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52081; Mature: 52081

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSSAHYRQLLARLPQIAVAADQFQVLNSAKDFKSRILSLIASATRRIYLVALYLQDDEA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCHH
GREILSALYASKQRNPALDIKLFVDFHRAQRGLIGKGKQGGNHLMYQEMAARHEHQIAIY
HHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
GVPVKGRELLGVLHLKGFIFDDTLLYSGASLNDIYLHQQDRYRFDRYHQITSPELTRCMV
ECCCCCHHHHHHHHHHCEEEECHHHCCCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHH
NYVDDLFLKSEAVQRLDRSDIPTAKQLKGPIRRFKHSLRLGQYRFESMPVNSQEIAITPM
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECC
TGLGKRGNQLNKMIRTLVRATEREIFICTPYFNPPKELNKDIEALLKRGCKVTIVVGDKT
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCC
ANDFFIPPEEKFTTIGGLPYLYETNLRKFAERNQHHIDAGRLNLMLWCCERNSYHLKGIF
CCCCCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEE
VDDEWALLTGNNLNPRAWALDLENGLLVYDRRHHLRAQFNGERENILANTKRISHFDQIE
ECCCEEEEECCCCCCCEEEEECCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QIKDYPEQVRKLLARIHRVRAHILLKRII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSSAHYRQLLARLPQIAVAADQFQVLNSAKDFKSRILSLIASATRRIYLVALYLQDDEA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCHH
GREILSALYASKQRNPALDIKLFVDFHRAQRGLIGKGKQGGNHLMYQEMAARHEHQIAIY
HHHHHHHHHHHCCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE
GVPVKGRELLGVLHLKGFIFDDTLLYSGASLNDIYLHQQDRYRFDRYHQITSPELTRCMV
ECCCCCHHHHHHHHHHCEEEECHHHCCCCCCCEEEEECCCCHHHHHHHCCCCHHHHHHHH
NYVDDLFLKSEAVQRLDRSDIPTAKQLKGPIRRFKHSLRLGQYRFESMPVNSQEIAITPM
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECC
TGLGKRGNQLNKMIRTLVRATEREIFICTPYFNPPKELNKDIEALLKRGCKVTIVVGDKT
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCC
ANDFFIPPEEKFTTIGGLPYLYETNLRKFAERNQHHIDAGRLNLMLWCCERNSYHLKGIF
CCCCCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEE
VDDEWALLTGNNLNPRAWALDLENGLLVYDRRHHLRAQFNGERENILANTKRISHFDQIE
ECCCEEEEECCCCCCCEEEEECCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QIKDYPEQVRKLLARIHRVRAHILLKRII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]