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The map label for this gene is sdaC [H]

Identifier: 145300659

GI number: 145300659

Start: 4084222

End: 4085493

Strand: Direct

Name: sdaC [H]

Synonym: ASA_3791

Alternate gene names: 145300659

Gene position: 4084222-4085493 (Clockwise)

Preceding gene: 145300658

Following gene: 145300663

Centisome position: 86.85

GC content: 62.11

Gene sequence:

>1272_bases
ATGAGTTTATCTGTAGATGTCGTCAAGGAGCTGTCTGCTTCCCAGCCAGCCGTTACCACCACTGCCCGTTGGCGCAGTCA
TGATACCCACTGGGTGATCAGCCTGTTTGGCACCGCCGTTGGCGCCGGCATACTCTTTCTGCCCATCAACCTGGGTCTGG
GCGGTATCTGGCCCCTGGTCATAGTCGCCGTACTGGCTGGCCCCATGACCTTCCTGGCTCACCGCGGGCTGGCCCGCTTC
GTGCTTTCTTCCTCCCGTCCCCATGCTGACTTCACCGAGGTGGCCGAGGAGCACTTCGGCAAGATGGCCGGTCGGCTCAT
CTCGGCGCTCTATTTCCTCTCCATCTTCCCGATACTGCTTATTTACGGCGTCGGGTTGACCAACACGGTCGAGAGCTTCA
TGGTCAACCAGCTCGGCATGGCGACCCCGAACCGGGTGATGCTCTCCGGCATGCTGGTGTTTGCCATGATCGCCGTGATG
ATGGCCGGGGAGAAGGCGATGCTGCGCGCCTTTGCCTTCATGGTCTATCCGCTGGCGGCCATTCTGGCGGCGCTTTCCTG
CTATCTCATTCCCCAGTGGCAGTGGCCGGAAGTCACCACCTTTGAGGGCGGCAGCTTCCTCAACACCGTCTGGCTGGCGC
TGCCGGTGACAGTGTTTGCCTTCAGCCACGCCGCCGCCATCTCCGGCTTTGCCAATGTGCAGCGGCGGGAATATGGCGAG
CAGGCGGAGGCCAAGAGCGGCCTGATCCTGCGCAACACCACCATAATGCTGGTGGGCTTCGTGCTCTTCTTCGTCTTCTC
CTGCGTGCTGAGCCTCACTCCGGCCCAGCTGGCCGAGGCCAAGGCCCAGAACGTCTCCGTGCTCTCCTATCTTGCCAACA
TCACCGACAACCCTGTGATAGTGACGCTGGGGCCGCTCATCGCCTTTATCGCCATCAGCTCCTCCTTCCTCGGCCACTTC
CTCGGTGCCCGCGAGAGCCTCAAGAGCCTGATCGCCAAGCCCACCGGCCTGTCGCTGGCCAAGGCGGACAAGCTGGGCAT
CGCCCTGATGTTCTTCGCCATCTGGGGGGCCGCCGTTATCAATCCGGGTATCCTAGGTCTGATGGAGACCCTCTCCGGCC
CCGTCATCGCCATGATCCTCTTCATCATGCCGGTGATAGCGGTCTACAAGGTGGAGGCGCTGGCCCGCTTCCGCCAGGGC
TGGACCAACGGCTTCATCCTGCTGACCGGGTCGCTGGCGGTGTCGGCGCTGATCTTCAGCCTGTTGAAGTAA

Upstream 100 bases:

>100_bases
CGTTATGGTAGTGATATGTTTCAGTCCCTCATTTTGAGAATTAAATCCTGATAAACCACAATACGCTCAGATTAAAACAC
TGACAAAAAGTGGATTAGTA

Downstream 100 bases:

>100_bases
CAGCGAGCTGCGGCAACAAAATGAGAGAGGCGACCCCGGGGTCGCCTCTCTTTTTTCATGGGGCCAAGGGCATCAGCCCA
GCTTGGCGCCGTTCTCCACC

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSLSVDVVKELSASQPAVTTTARWRSHDTHWVISLFGTAVGAGILFLPINLGLGGIWPLVIVAVLAGPMTFLAHRGLARF
VLSSSRPHADFTEVAEEHFGKMAGRLISALYFLSIFPILLIYGVGLTNTVESFMVNQLGMATPNRVMLSGMLVFAMIAVM
MAGEKAMLRAFAFMVYPLAAILAALSCYLIPQWQWPEVTTFEGGSFLNTVWLALPVTVFAFSHAAAISGFANVQRREYGE
QAEAKSGLILRNTTIMLVGFVLFFVFSCVLSLTPAQLAEAKAQNVSVLSYLANITDNPVIVTLGPLIAFIAISSSFLGHF
LGARESLKSLIAKPTGLSLAKADKLGIALMFFAIWGAAVINPGILGLMETLSGPVIAMILFIMPVIAVYKVEALARFRQG
WTNGFILLTGSLAVSALIFSLLK

Sequences:

>Translated_423_residues
MSLSVDVVKELSASQPAVTTTARWRSHDTHWVISLFGTAVGAGILFLPINLGLGGIWPLVIVAVLAGPMTFLAHRGLARF
VLSSSRPHADFTEVAEEHFGKMAGRLISALYFLSIFPILLIYGVGLTNTVESFMVNQLGMATPNRVMLSGMLVFAMIAVM
MAGEKAMLRAFAFMVYPLAAILAALSCYLIPQWQWPEVTTFEGGSFLNTVWLALPVTVFAFSHAAAISGFANVQRREYGE
QAEAKSGLILRNTTIMLVGFVLFFVFSCVLSLTPAQLAEAKAQNVSVLSYLANITDNPVIVTLGPLIAFIAISSSFLGHF
LGARESLKSLIAKPTGLSLAKADKLGIALMFFAIWGAAVINPGILGLMETLSGPVIAMILFIMPVIAVYKVEALARFRQG
WTNGFILLTGSLAVSALIFSLLK
>Mature_422_residues
SLSVDVVKELSASQPAVTTTARWRSHDTHWVISLFGTAVGAGILFLPINLGLGGIWPLVIVAVLAGPMTFLAHRGLARFV
LSSSRPHADFTEVAEEHFGKMAGRLISALYFLSIFPILLIYGVGLTNTVESFMVNQLGMATPNRVMLSGMLVFAMIAVMM
AGEKAMLRAFAFMVYPLAAILAALSCYLIPQWQWPEVTTFEGGSFLNTVWLALPVTVFAFSHAAAISGFANVQRREYGEQ
AEAKSGLILRNTTIMLVGFVLFFVFSCVLSLTPAQLAEAKAQNVSVLSYLANITDNPVIVTLGPLIAFIAISSSFLGHFL
GARESLKSLIAKPTGLSLAKADKLGIALMFFAIWGAAVINPGILGLMETLSGPVIAMILFIMPVIAVYKVEALARFRQGW
TNGFILLTGSLAVSALIFSLLK

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=410, Percent_Identity=50.7317073170732, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1789504, Length=431, Percent_Identity=38.7470997679814, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI1789211, Length=407, Percent_Identity=35.6265356265356, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1789961, Length=397, Percent_Identity=25.6926952141058, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693183, Length=428, Percent_Identity=27.3364485981308, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 45456; Mature: 45324

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVDVVKELSASQPAVTTTARWRSHDTHWVISLFGTAVGAGILFLPINLGLGGIWPLV
CCCCHHHHHHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHH
IVAVLAGPMTFLAHRGLARFVLSSSRPHADFTEVAEEHFGKMAGRLISALYFLSIFPILL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYGVGLTNTVESFMVNQLGMATPNRVMLSGMLVFAMIAVMMAGEKAMLRAFAFMVYPLAA
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ILAALSCYLIPQWQWPEVTTFEGGSFLNTVWLALPVTVFAFSHAAAISGFANVQRREYGE
HHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QAEAKSGLILRNTTIMLVGFVLFFVFSCVLSLTPAQLAEAKAQNVSVLSYLANITDNPVI
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
VTLGPLIAFIAISSSFLGHFLGARESLKSLIAKPTGLSLAKADKLGIALMFFAIWGAAVI
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NPGILGLMETLSGPVIAMILFIMPVIAVYKVEALARFRQGWTNGFILLTGSLAVSALIFS
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LLK
HHC
>Mature Secondary Structure 
SLSVDVVKELSASQPAVTTTARWRSHDTHWVISLFGTAVGAGILFLPINLGLGGIWPLV
CCCHHHHHHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHCCCCHHHHHH
IVAVLAGPMTFLAHRGLARFVLSSSRPHADFTEVAEEHFGKMAGRLISALYFLSIFPILL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYGVGLTNTVESFMVNQLGMATPNRVMLSGMLVFAMIAVMMAGEKAMLRAFAFMVYPLAA
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ILAALSCYLIPQWQWPEVTTFEGGSFLNTVWLALPVTVFAFSHAAAISGFANVQRREYGE
HHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QAEAKSGLILRNTTIMLVGFVLFFVFSCVLSLTPAQLAEAKAQNVSVLSYLANITDNPVI
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
VTLGPLIAFIAISSSFLGHFLGARESLKSLIAKPTGLSLAKADKLGIALMFFAIWGAAVI
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NPGILGLMETLSGPVIAMILFIMPVIAVYKVEALARFRQGWTNGFILLTGSLAVSALIFS
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
LLK
HHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]