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The map label for this gene is cysQ [H]

Identifier: 145300658

GI number: 145300658

Start: 4082997

End: 4083809

Strand: Direct

Name: cysQ [H]

Synonym: ASA_3790

Alternate gene names: 145300658

Gene position: 4082997-4083809 (Clockwise)

Preceding gene: 145300657

Following gene: 145300659

Centisome position: 86.83

GC content: 62.36

Gene sequence:

>813_bases
ATGCAGGAGTTGTTGGCCTGGGTTCCAGGGGTCAAGGAGATCGCCCGCGAAGCGGGACGTATCCTTCACGAAATCTATCA
CGGCGGTCAGTTCGAGCGTCAGCTGAAGGAGGATGCGACCCCGGTCACCAGTGCCGATCTTGCTGCCGATGCCTACCTCA
AACAGGCGCTGTCGGCGCTCACCCCCCATGTACCCGTGCTGACCGAAGAGGCGGCCGATGTGCCCTTCAGTCAGCGATCC
AACTGGCGGCAGTACTGGCTGGTGGATCCCCTCGACGGCACTGGTGAGTTCATTGCCGGCAGCGGCGATTTCGCCACCCT
GATCGCCCTGGTTCGGGACAACGTGCCGGTGCTCGGTGTCATCTACGCCCCCGAGTCTGACGTGCTCTACTGGGCGGTGC
GTGGTCACGGCGCCTTCAAGGAGGTGAACGGCGAGACCTTGCCTATCAGCGCCATGCATCACGAACATGACCAGCCAGAC
TCCCTGGTGGTGGCCATCAGCCGTCGCCAGAAGCTGGAGAATCTGACCCGTCGCCTCAATCCGGCCATCAACTACGAGCT
GATCCCGCTCGGTTCCAGCTCCCTCAAGTCCTGCCTGGTGGCAGAAGGGGCTGCCGATTGCTATGTGCGACTCGGCCCCA
CCGGCGAGTGGGATACCGCCGCTGCACAGTGCATCGTCGAGGCGGCTGGCGGTCGTATCCTCAGCCTGGCGTTGCAACCG
CTTAGCTACAACGAAACCGAGTCGCTGGAGAACCCGGACTTTATAGTGATGGGAGATCCGGATCTCGCCTGGGGCACTAT
TCTCGCTCACTGA

Upstream 100 bases:

>100_bases
CGCGCAGCATCAGTGCCCTGCTGCTGGCCCAGAAGTGGCTGGCGGAGCAGGAAAACTAGCCCGAACGTGGGCAAAGGCAA
TAAAAACAGAGGATAACAAG

Downstream 100 bases:

>100_bases
GTTGGCTGACATTTCATCGCAAGACTCAATCAGGCGACCTCATGGTCGCCTGATTGTCTGGTGTGATCCGCTGCTTTTAT
CCGGCACGCATAGGAGTATC

Product: CysQ protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQELLAWVPGVKEIAREAGRILHEIYHGGQFERQLKEDATPVTSADLAADAYLKQALSALTPHVPVLTEEAADVPFSQRS
NWRQYWLVDPLDGTGEFIAGSGDFATLIALVRDNVPVLGVIYAPESDVLYWAVRGHGAFKEVNGETLPISAMHHEHDQPD
SLVVAISRRQKLENLTRRLNPAINYELIPLGSSSLKSCLVAEGAADCYVRLGPTGEWDTAAAQCIVEAAGGRILSLALQP
LSYNETESLENPDFIVMGDPDLAWGTILAH

Sequences:

>Translated_270_residues
MQELLAWVPGVKEIAREAGRILHEIYHGGQFERQLKEDATPVTSADLAADAYLKQALSALTPHVPVLTEEAADVPFSQRS
NWRQYWLVDPLDGTGEFIAGSGDFATLIALVRDNVPVLGVIYAPESDVLYWAVRGHGAFKEVNGETLPISAMHHEHDQPD
SLVVAISRRQKLENLTRRLNPAINYELIPLGSSSLKSCLVAEGAADCYVRLGPTGEWDTAAAQCIVEAAGGRILSLALQP
LSYNETESLENPDFIVMGDPDLAWGTILAH
>Mature_270_residues
MQELLAWVPGVKEIAREAGRILHEIYHGGQFERQLKEDATPVTSADLAADAYLKQALSALTPHVPVLTEEAADVPFSQRS
NWRQYWLVDPLDGTGEFIAGSGDFATLIALVRDNVPVLGVIYAPESDVLYWAVRGHGAFKEVNGETLPISAMHHEHDQPD
SLVVAISRRQKLENLTRRLNPAINYELIPLGSSSLKSCLVAEGAADCYVRLGPTGEWDTAAAQCIVEAAGGRILSLALQP
LSYNETESLENPDFIVMGDPDLAWGTILAH

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=239, Percent_Identity=27.1966527196653, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031789, Length=239, Percent_Identity=27.1966527196653, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=29.535864978903, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790659, Length=248, Percent_Identity=43.1451612903226, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1788882, Length=220, Percent_Identity=27.7272727272727, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=176, Percent_Identity=30.1136363636364, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=234, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202572, Length=231, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=207, Percent_Identity=28.5024154589372, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664922, Length=264, Percent_Identity=28.4090909090909, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=230, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24664918, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357329, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29435; Mature: 29435

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELLAWVPGVKEIAREAGRILHEIYHGGQFERQLKEDATPVTSADLAADAYLKQALSAL
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TPHVPVLTEEAADVPFSQRSNWRQYWLVDPLDGTGEFIAGSGDFATLIALVRDNVPVLGV
CCCCCEEECHHCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
IYAPESDVLYWAVRGHGAFKEVNGETLPISAMHHEHDQPDSLVVAISRRQKLENLTRRLN
EECCCCCEEEEEEECCCCHHHCCCCEEEEEHHCCCCCCCCCEEEEHHHHHHHHHHHHHCC
PAINYELIPLGSSSLKSCLVAEGAADCYVRLGPTGEWDTAAAQCIVEAAGGRILSLALQP
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECC
LSYNETESLENPDFIVMGDPDLAWGTILAH
CCCCCCCCCCCCCEEEECCCCCCHHHEECC
>Mature Secondary Structure
MQELLAWVPGVKEIAREAGRILHEIYHGGQFERQLKEDATPVTSADLAADAYLKQALSAL
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TPHVPVLTEEAADVPFSQRSNWRQYWLVDPLDGTGEFIAGSGDFATLIALVRDNVPVLGV
CCCCCEEECHHCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHCCCCEEEE
IYAPESDVLYWAVRGHGAFKEVNGETLPISAMHHEHDQPDSLVVAISRRQKLENLTRRLN
EECCCCCEEEEEEECCCCHHHCCCCEEEEEHHCCCCCCCCCEEEEHHHHHHHHHHHHHCC
PAINYELIPLGSSSLKSCLVAEGAADCYVRLGPTGEWDTAAAQCIVEAAGGRILSLALQP
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECC
LSYNETESLENPDFIVMGDPDLAWGTILAH
CCCCCCCCCCCCCEEEECCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]