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The map label for this gene is hdfR [H]

Identifier: 145299628

GI number: 145299628

Start: 2898644

End: 2899519

Strand: Direct

Name: hdfR [H]

Synonym: ASA_2702

Alternate gene names: 145299628

Gene position: 2898644-2899519 (Clockwise)

Preceding gene: 145299627

Following gene: 145299635

Centisome position: 61.64

GC content: 62.56

Gene sequence:

>876_bases
ATGGATACCGAACTGCTTCGGACCTTTATCGAGGTCAGCAAGACCCGGCACTTTGGCCGGGCTGCTGAGAATCTCTACCT
GACCCAGTCGGCGGTGAGCTTTCGGATCCGCCAGCTTGAGCAGCAACTCGGGGTCAGTCTGTTTGCCCGTCATCGCAACA
ACATCCGCCTTACCGCGTCCGGTGAGCGTCTGCTGCCCTATGCAGACGCCATCTTGCATACCCTGGGTCGGGCCAAGCAG
GACGTTGCGCTCTCCCCCGGTTTCAGCCAGCAGCTCGCCATAGGCGCGCCCGCCGTGTTCTGGGAGCTCGATTTCAACGA
CTGGCTCAATCATGTCTATGCGCTGGCTCCCGGCCTCGCCGTGCGGCTCGAAACCGCATCCCGCGAGCACCTGTGCCGCC
AGCTGCTGGAGCGCTCCCTCGACTTGGCCCTGCTATCCGAGCCAACCAAGATCGATGAGATTGCCCTGTATCCCATCGGC
GAACTGGTGTTTGAACTGGTGAGCCGGGATAGCACAGCCAACGCCGACAGCCTGATGCAAATGCCCCACATTCACCTCGA
CTGGGGCACCAGTCTGGAGCCGCAACCCAGCCGATTGCAGAGCCTGCAAAAAACCCCCGTGCTGCACTCGAGCTCCGCCA
ACATGGCGCTGCAGTTCGTGCTGGCCAATGGGGGTGCCGCCTACCTGCCACGGCGGATGGTGAGTCCCTTCCTGGAAAAG
GGGCAGCTGCATCTGGTGGAGGGAGGCCAGCCGCTCAGTCGTCCGCTCTACCTCGCCTATCTGGAGAAATCCGATCGCCG
GGAGCTGATCGATCGGCTGCTGACCCTGCCGCTCGGTTGGGATGGAGCCGATCTGCGCCTGCCGCAGCCTGAATAA

Upstream 100 bases:

>100_bases
TGCATCGTCTGTGCACAGTCGCAGGCGGCGCCAACGAGGAAACCGGCGGCGGTGGTTTTGACGGCGGCAACGGCGGCGGT
AGCGACGAGTCCATCGATTA

Downstream 100 bases:

>100_bases
CCTCGGGCGATAGCACAGACAGAAAAGGGGCCGAAAAGGCCCCTTTTTTATGGTGCTTGCGTGCAATCGCATCAGCCGTG
CTGGCGGCGATCGTTGGCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDTELLRTFIEVSKTRHFGRAAENLYLTQSAVSFRIRQLEQQLGVSLFARHRNNIRLTASGERLLPYADAILHTLGRAKQ
DVALSPGFSQQLAIGAPAVFWELDFNDWLNHVYALAPGLAVRLETASREHLCRQLLERSLDLALLSEPTKIDEIALYPIG
ELVFELVSRDSTANADSLMQMPHIHLDWGTSLEPQPSRLQSLQKTPVLHSSSANMALQFVLANGGAAYLPRRMVSPFLEK
GQLHLVEGGQPLSRPLYLAYLEKSDRRELIDRLLTLPLGWDGADLRLPQPE

Sequences:

>Translated_291_residues
MDTELLRTFIEVSKTRHFGRAAENLYLTQSAVSFRIRQLEQQLGVSLFARHRNNIRLTASGERLLPYADAILHTLGRAKQ
DVALSPGFSQQLAIGAPAVFWELDFNDWLNHVYALAPGLAVRLETASREHLCRQLLERSLDLALLSEPTKIDEIALYPIG
ELVFELVSRDSTANADSLMQMPHIHLDWGTSLEPQPSRLQSLQKTPVLHSSSANMALQFVLANGGAAYLPRRMVSPFLEK
GQLHLVEGGQPLSRPLYLAYLEKSDRRELIDRLLTLPLGWDGADLRLPQPE
>Mature_291_residues
MDTELLRTFIEVSKTRHFGRAAENLYLTQSAVSFRIRQLEQQLGVSLFARHRNNIRLTASGERLLPYADAILHTLGRAKQ
DVALSPGFSQQLAIGAPAVFWELDFNDWLNHVYALAPGLAVRLETASREHLCRQLLERSLDLALLSEPTKIDEIALYPIG
ELVFELVSRDSTANADSLMQMPHIHLDWGTSLEPQPSRLQSLQKTPVLHSSSANMALQFVLANGGAAYLPRRMVSPFLEK
GQLHLVEGGQPLSRPLYLAYLEKSDRRELIDRLLTLPLGWDGADLRLPQPE

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=282, Percent_Identity=45.3900709219858, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=34.8387096774194, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786713, Length=306, Percent_Identity=26.797385620915, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788626, Length=146, Percent_Identity=34.2465753424658, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=27.5167785234899, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32676; Mature: 32676

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLRTFIEVSKTRHFGRAAENLYLTQSAVSFRIRQLEQQLGVSLFARHRNNIRLTAS
CCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEC
GERLLPYADAILHTLGRAKQDVALSPGFSQQLAIGAPAVFWELDFNDWLNHVYALAPGLA
CCCCCHHHHHHHHHHCCCCCCCEECCCCCCCEECCCCEEEEEECHHHHHHHHHHHCCCCE
VRLETASREHLCRQLLERSLDLALLSEPTKIDEIALYPIGELVFELVSRDSTANADSLMQ
EEEECCCHHHHHHHHHHHCCCEEECCCCCCCCCEEECCHHHHHHHHHHCCCCCCHHHHHH
MPHIHLDWGTSLEPQPSRLQSLQKTPVLHSSSANMALQFVLANGGAAYLPRRMVSPFLEK
CCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHC
GQLHLVEGGQPLSRPLYLAYLEKSDRRELIDRLLTLPLGWDGADLRLPQPE
CCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDTELLRTFIEVSKTRHFGRAAENLYLTQSAVSFRIRQLEQQLGVSLFARHRNNIRLTAS
CCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEC
GERLLPYADAILHTLGRAKQDVALSPGFSQQLAIGAPAVFWELDFNDWLNHVYALAPGLA
CCCCCHHHHHHHHHHCCCCCCCEECCCCCCCEECCCCEEEEEECHHHHHHHHHHHCCCCE
VRLETASREHLCRQLLERSLDLALLSEPTKIDEIALYPIGELVFELVSRDSTANADSLMQ
EEEECCCHHHHHHHHHHHCCCEEECCCCCCCCCEEECCHHHHHHHHHHCCCCCCHHHHHH
MPHIHLDWGTSLEPQPSRLQSLQKTPVLHSSSANMALQFVLANGGAAYLPRRMVSPFLEK
CCEEEECCCCCCCCCHHHHHHHHHCCCEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHC
GQLHLVEGGQPLSRPLYLAYLEKSDRRELIDRLLTLPLGWDGADLRLPQPE
CCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA