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The map label for this gene is dcuC [H]

Identifier: 145299324

GI number: 145299324

Start: 2522488

End: 2523759

Strand: Direct

Name: dcuC [H]

Synonym: ASA_2368

Alternate gene names: 145299324

Gene position: 2522488-2523759 (Clockwise)

Preceding gene: 145299322

Following gene: 145299325

Centisome position: 53.64

GC content: 61.79

Gene sequence:

>1272_bases
ATGATGGAACTCCTTATTGGTACCCTGGTCACCCTGACCGTGGGGCGCTACATCTTCAAGGGCTACTCGGCCACCGGGGT
GCTGCTCAGCGGCGGTTTGCTGCTGCTGACCATTACCGCCCTGATGGGCAAGACGGTGCTGCCCGCCAGCGTCACCTCCA
CCGGCCATGTTGCCACCGATATCTTCGAATATGTGCGCTTCCTGCTGGTGGATCGCGGCGGTGGCCTGGGCATGCTGATC
ATGGTGCTGTGCGGTTTTGCCGGCTACATGAGCCACATCGGCGCCAACACCATTTTGGTGAAGCTGGCCAGCAAACCGCT
CGGCATCATCAAATCCCCCTACATACTGCTGGTGGCCGCCTATTTGGTCGCCTGTGCCATGTCGCTGGCGGTGAGCTCTG
CAACCGGTCTGGGCGTGCTCTTGATGGCCACCCTGTTCCCGCTGATGGTCAACATGGGGATCTCCCGTGGCGCCGCAGCC
GCTGTGTGTGCTTCTCCAGCCGCCATCATTCTGGCGCCCACCTCGGGTGACGTCGTGATGGCAGCCCAGGCCGCCAACAT
GGAGCTGCTCGACTTTGCCTTCAAGCTGACCCTGCCCATCTCGCTGGTGGCCATCGCCGCCATGGCGGTCGCCCACTTCT
TCTGGCAGCGTTATCTTGACCAGAAATCGGGCGAGCACAACGAGCCTGTCGCACCGAGCGATCTCATCACGGATGCTCCC
GGCTTCTACGCCATACTGCCGTTTACCCCCATCATCGGCGTGCTGCTGTTTGACGGCAAAGTGGGCCCCAAACTCGACAT
AGTGACCATCATCGTCATCTGTCTGGTGCTGGCTGCCTTGCTGGAACTGGTGCGCAAGCGCAACGGCAAGGATCTGCTCG
AGGGTCTGCAGGTATGCTGGCGCAGCATGGCAGACGCCTTCTCCGGCGTGGTCATGCTCTTGGTGGGTGCCGGTGTGTTT
GCCCAGGGTCTGATGGGACTGGGCTTCATCGCGAACCTCCTGGATCTGGCCCAGAGCTTTGGCACCGGCGGTATTGTCAT
CATGCTGGTACTGGTGGTCATCACCACCCTGGCCGCCTTTACCACAGGCTCCGGCAATGCTCCCTTCTACGCCTTCGTGG
AGCTGATCCCGCACCTGGCCACCAGCCTCGGCGTCAATCCCGCCTATCTGGTCATCCCCATGCTGCAAGCCTCCAACCTG
GGTCGCACCATCTCGCCTGTCTCCGGCCTGGTGGTGGTGATCCTCGCCACCCAGATCATGGTTCCCGCCTGA

Upstream 100 bases:

>100_bases
GCCGAGTTTTCTGTTGATGCTTTCCGCAATTGACCAGATTAACCGCCAAGTTAACCCATGAAATGCATCCACCTTCATTT
CGTACTCAGGAACTCACTCT

Downstream 100 bases:

>100_bases
GATCTGCGTTGGACCAACGGGATTCCCTGAGCAGGCTCCCGCTTGGTCCTTCTCTTCCCTTACTAGCCCGGCGTCCTGCC
GGGCTAGTATCTTCCCCCTA

Product: anaerobic C4-dicarboxylate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MMELLIGTLVTLTVGRYIFKGYSATGVLLSGGLLLLTITALMGKTVLPASVTSTGHVATDIFEYVRFLLVDRGGGLGMLI
MVLCGFAGYMSHIGANTILVKLASKPLGIIKSPYILLVAAYLVACAMSLAVSSATGLGVLLMATLFPLMVNMGISRGAAA
AVCASPAAIILAPTSGDVVMAAQAANMELLDFAFKLTLPISLVAIAAMAVAHFFWQRYLDQKSGEHNEPVAPSDLITDAP
GFYAILPFTPIIGVLLFDGKVGPKLDIVTIIVICLVLAALLELVRKRNGKDLLEGLQVCWRSMADAFSGVVMLLVGAGVF
AQGLMGLGFIANLLDLAQSFGTGGIVIMLVLVVITTLAAFTTGSGNAPFYAFVELIPHLATSLGVNPAYLVIPMLQASNL
GRTISPVSGLVVVILATQIMVPA

Sequences:

>Translated_423_residues
MMELLIGTLVTLTVGRYIFKGYSATGVLLSGGLLLLTITALMGKTVLPASVTSTGHVATDIFEYVRFLLVDRGGGLGMLI
MVLCGFAGYMSHIGANTILVKLASKPLGIIKSPYILLVAAYLVACAMSLAVSSATGLGVLLMATLFPLMVNMGISRGAAA
AVCASPAAIILAPTSGDVVMAAQAANMELLDFAFKLTLPISLVAIAAMAVAHFFWQRYLDQKSGEHNEPVAPSDLITDAP
GFYAILPFTPIIGVLLFDGKVGPKLDIVTIIVICLVLAALLELVRKRNGKDLLEGLQVCWRSMADAFSGVVMLLVGAGVF
AQGLMGLGFIANLLDLAQSFGTGGIVIMLVLVVITTLAAFTTGSGNAPFYAFVELIPHLATSLGVNPAYLVIPMLQASNL
GRTISPVSGLVVVILATQIMVPA
>Mature_423_residues
MMELLIGTLVTLTVGRYIFKGYSATGVLLSGGLLLLTITALMGKTVLPASVTSTGHVATDIFEYVRFLLVDRGGGLGMLI
MVLCGFAGYMSHIGANTILVKLASKPLGIIKSPYILLVAAYLVACAMSLAVSSATGLGVLLMATLFPLMVNMGISRGAAA
AVCASPAAIILAPTSGDVVMAAQAANMELLDFAFKLTLPISLVAIAAMAVAHFFWQRYLDQKSGEHNEPVAPSDLITDAP
GFYAILPFTPIIGVLLFDGKVGPKLDIVTIIVICLVLAALLELVRKRNGKDLLEGLQVCWRSMADAFSGVVMLLVGAGVF
AQGLMGLGFIANLLDLAQSFGTGGIVIMLVLVVITTLAAFTTGSGNAPFYAFVELIPHLATSLGVNPAYLVIPMLQASNL
GRTISPVSGLVVVILATQIMVPA

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=390, Percent_Identity=70, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1789622, Length=419, Percent_Identity=35.3221957040573, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 44016; Mature: 44016

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELLIGTLVTLTVGRYIFKGYSATGVLLSGGLLLLTITALMGKTVLPASVTSTGHVATD
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IFEYVRFLLVDRGGGLGMLIMVLCGFAGYMSHIGANTILVKLASKPLGIIKSPYILLVAA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHCCHHHHHHHH
YLVACAMSLAVSSATGLGVLLMATLFPLMVNMGISRGAAAAVCASPAAIILAPTSGDVVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAQAANMELLDFAFKLTLPISLVAIAAMAVAHFFWQRYLDQKSGEHNEPVAPSDLITDAP
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC
GFYAILPFTPIIGVLLFDGKVGPKLDIVTIIVICLVLAALLELVRKRNGKDLLEGLQVCW
CCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSMADAFSGVVMLLVGAGVFAQGLMGLGFIANLLDLAQSFGTGGIVIMLVLVVITTLAAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPHLATSLGVNPAYLVIPMLQASNLGRTISPVSGLVVVILATQIM
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHH
VPA
CCC
>Mature Secondary Structure
MMELLIGTLVTLTVGRYIFKGYSATGVLLSGGLLLLTITALMGKTVLPASVTSTGHVATD
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IFEYVRFLLVDRGGGLGMLIMVLCGFAGYMSHIGANTILVKLASKPLGIIKSPYILLVAA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHCCHHHHHHHH
YLVACAMSLAVSSATGLGVLLMATLFPLMVNMGISRGAAAAVCASPAAIILAPTSGDVVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAQAANMELLDFAFKLTLPISLVAIAAMAVAHFFWQRYLDQKSGEHNEPVAPSDLITDAP
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCC
GFYAILPFTPIIGVLLFDGKVGPKLDIVTIIVICLVLAALLELVRKRNGKDLLEGLQVCW
CCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSMADAFSGVVMLLVGAGVFAQGLMGLGFIANLLDLAQSFGTGGIVIMLVLVVITTLAAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPHLATSLGVNPAYLVIPMLQASNLGRTISPVSGLVVVILATQIM
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHH
VPA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]