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The map label for this gene is ushA [C]

Identifier: 145299325

GI number: 145299325

Start: 2523904

End: 2525565

Strand: Direct

Name: ushA [C]

Synonym: ASA_2369

Alternate gene names: 145299325

Gene position: 2523904-2525565 (Clockwise)

Preceding gene: 145299324

Following gene: 145299326

Centisome position: 53.67

GC content: 63.36

Gene sequence:

>1662_bases
ATGAGTATTACGGTTCAACTTGCCCATTTCAGTGACTGCCACTCCCATTTCGATGGCGCCCCCATGCGCTTCTTCCCTGT
TGGCGAGTCAGAATGGCGCACCCCGTGTGGCGGCTATGCCCGCATTCTTACCAGACTCACCGCCCTGCGCCAGCAGGCTG
ATGCGGCGGGCCAGACCTGCCTGTTCCTGCACGGTGGCGATACCTTTCAGGGGTCACTCTATTTCAACCGTTTCAAGGGA
CGGGCCAATGCCGACTTGCTGAGCCTGTTGCGACCCGATGCCATGGTGATCGGCAATCACGAGTTCGATCTGGGCAACGG
TCCTCTGGTGGAATTTTTGCGCCAGCTCGATTTTCCCGTGCTGGCCGCCAACCTCGACAGCAGCCAGGAGCCGGCCGATA
CCCCGCTGCGCTTGCAGGGCCTGCCCATGCTTCATGATGCCAGCCGTCCCTGGCACAAACGCGTAATAGACGGCGTCCCC
TTTGCGCTGCTTGGCATCACGCTGCCGCAGATGGCCGCCATCGCCAATCCGGATCCCCATACCCGCTTTCATGGTATCGA
TGACACCCTGACCGCCGCGATCGGCGAGATCAAGGCTGCGGGCATCCACCACATTATTTTGCTTAGCCACCTGGGACTGG
AGCAAGACAAGCGCCTTGCGGCCCGCTTTCCGGAACTGAGCCTCATCATTGGCGGCCACACCCACAGTCAACTGGGGGAT
CTCGCGCCCTTGGGGCTCGAGAGCGATGGCAGTTATCCGTTGATGGTGAACGACGTGGCTATCCTCCATGCCGCCCACAG
CGCGCTCTGCCTGGGGGTATGCGAGCTGGAGTTTGATGCCCGCGGACGTGTGAGTCGCAGTCAAGGCCAACTGGAATGGT
TGCCCTGGCAACCCTGGCCGTTTGCCTCAGAGCCCCCTGCAGGGCTGTACTTCTGCGAGCCGGCCCCCGAGCTCGAGCAG
CATCTGGCCAAACGCTACCGGCCCGAGCTCGAGACCATGACCCAGCGCATCGTGACCCATCTCGCCGGGCCGCTCCATCA
TCAGCGCCTGCCCGATGCCAATCTGCCCGCCGGCAGCCAGGTTGCTCCGCTGGTGGCCCACGCCATGCTGATCGGTGCCC
GCGAACAGGTTGGTCAGGTGGATTTCGCCCTGCACAACGCAGGGGGGGTGCGCTGCTCCCTGGAGCCAGGTCCCTTGAGC
GAAGCGGACATCGCAGGTCGCCTGCTCCCGTTTGCCATCCCCCTCACCCTCTACCGGGTGCATGGCCATGAGCTGGCTGA
GGCGCTGGAAGGCGCCATCGACAACGCCACCAACAACGGCGTGACGGGCAATGGTAACGGCAGCTTCCCCTACACAGCCG
GGATGCGCTTCTGTTATCAGGCTGATCGTCCCAAGGGGGCCAGGATCACCCGTCTGGAGTGGGAAAGCGCGCCAGGCTGC
TGGCAGCCAGTCGAGGCAGACGCCATCTATCGGGGAGTATCCAGTGCCTATACCGCCTCCGGCAAAGAGGGCTACACGGC
GTTGGCTCGCACCCTGACCCAGCACAATCAGGAGCTCGGCATTACGCTGGCGGATGCCTTCATCCGCTGGGCCCGTTATC
TGCCCGAGCTCGCAACCCTGCCGGAGCTGGTGGAGTATCACGGCCCTCACGCCATGCCGTGA

Upstream 100 bases:

>100_bases
GGTCCTTCTCTTCCCTTACTAGCCCGGCGTCCTGCCGGGCTAGTATCTTCCCCCTAGGTTGGAGTAGACTCGGTGCTCTT
TTTCTCTAAGGAGGACCGAG

Downstream 100 bases:

>100_bases
GTCGGCGGGTAAGGGACTCACGTTACCGCTTCTCCTTCCTGTGTCAGAAAAAGTGCCCCTTTCTTGCCAGGAAGCGGCAC
TTTTGCAAATTATTTCAAGC

Product: 5'-nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MSITVQLAHFSDCHSHFDGAPMRFFPVGESEWRTPCGGYARILTRLTALRQQADAAGQTCLFLHGGDTFQGSLYFNRFKG
RANADLLSLLRPDAMVIGNHEFDLGNGPLVEFLRQLDFPVLAANLDSSQEPADTPLRLQGLPMLHDASRPWHKRVIDGVP
FALLGITLPQMAAIANPDPHTRFHGIDDTLTAAIGEIKAAGIHHIILLSHLGLEQDKRLAARFPELSLIIGGHTHSQLGD
LAPLGLESDGSYPLMVNDVAILHAAHSALCLGVCELEFDARGRVSRSQGQLEWLPWQPWPFASEPPAGLYFCEPAPELEQ
HLAKRYRPELETMTQRIVTHLAGPLHHQRLPDANLPAGSQVAPLVAHAMLIGAREQVGQVDFALHNAGGVRCSLEPGPLS
EADIAGRLLPFAIPLTLYRVHGHELAEALEGAIDNATNNGVTGNGNGSFPYTAGMRFCYQADRPKGARITRLEWESAPGC
WQPVEADAIYRGVSSAYTASGKEGYTALARTLTQHNQELGITLADAFIRWARYLPELATLPELVEYHGPHAMP

Sequences:

>Translated_553_residues
MSITVQLAHFSDCHSHFDGAPMRFFPVGESEWRTPCGGYARILTRLTALRQQADAAGQTCLFLHGGDTFQGSLYFNRFKG
RANADLLSLLRPDAMVIGNHEFDLGNGPLVEFLRQLDFPVLAANLDSSQEPADTPLRLQGLPMLHDASRPWHKRVIDGVP
FALLGITLPQMAAIANPDPHTRFHGIDDTLTAAIGEIKAAGIHHIILLSHLGLEQDKRLAARFPELSLIIGGHTHSQLGD
LAPLGLESDGSYPLMVNDVAILHAAHSALCLGVCELEFDARGRVSRSQGQLEWLPWQPWPFASEPPAGLYFCEPAPELEQ
HLAKRYRPELETMTQRIVTHLAGPLHHQRLPDANLPAGSQVAPLVAHAMLIGAREQVGQVDFALHNAGGVRCSLEPGPLS
EADIAGRLLPFAIPLTLYRVHGHELAEALEGAIDNATNNGVTGNGNGSFPYTAGMRFCYQADRPKGARITRLEWESAPGC
WQPVEADAIYRGVSSAYTASGKEGYTALARTLTQHNQELGITLADAFIRWARYLPELATLPELVEYHGPHAMP
>Mature_552_residues
SITVQLAHFSDCHSHFDGAPMRFFPVGESEWRTPCGGYARILTRLTALRQQADAAGQTCLFLHGGDTFQGSLYFNRFKGR
ANADLLSLLRPDAMVIGNHEFDLGNGPLVEFLRQLDFPVLAANLDSSQEPADTPLRLQGLPMLHDASRPWHKRVIDGVPF
ALLGITLPQMAAIANPDPHTRFHGIDDTLTAAIGEIKAAGIHHIILLSHLGLEQDKRLAARFPELSLIIGGHTHSQLGDL
APLGLESDGSYPLMVNDVAILHAAHSALCLGVCELEFDARGRVSRSQGQLEWLPWQPWPFASEPPAGLYFCEPAPELEQH
LAKRYRPELETMTQRIVTHLAGPLHHQRLPDANLPAGSQVAPLVAHAMLIGAREQVGQVDFALHNAGGVRCSLEPGPLSE
ADIAGRLLPFAIPLTLYRVHGHELAEALEGAIDNATNNGVTGNGNGSFPYTAGMRFCYQADRPKGARITRLEWESAPGCW
QPVEADAIYRGVSSAYTASGKEGYTALARTLTQHNQELGITLADAFIRWARYLPELATLPELVEYHGPHAMP

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=558, Percent_Identity=24.3727598566308, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI19922446, Length=530, Percent_Identity=27.9245283018868, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24654424, Length=530, Percent_Identity=27.9245283018868, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24641187, Length=551, Percent_Identity=27.4047186932849, Blast_Score=158, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28573524, Length=531, Percent_Identity=25.9887005649718, Blast_Score=155, Evalue=9e-38,
Organism=Drosophila melanogaster, GI19922444, Length=532, Percent_Identity=25, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI221329836, Length=528, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 60322; Mature: 60191

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITVQLAHFSDCHSHFDGAPMRFFPVGESEWRTPCGGYARILTRLTALRQQADAAGQTC
CEEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LFLHGGDTFQGSLYFNRFKGRANADLLSLLRPDAMVIGNHEFDLGNGPLVEFLRQLDFPV
EEEECCCCEECCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCE
LAANLDSSQEPADTPLRLQGLPMLHDASRPWHKRVIDGVPFALLGITLPQMAAIANPDPH
EEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
TRFHGIDDTLTAAIGEIKAAGIHHIILLSHLGLEQDKRLAARFPELSLIIGGHTHSQLGD
CEECCCCHHHHHHHHHHHHCCHHHEEHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHHC
LAPLGLESDGSYPLMVNDVAILHAAHSALCLGVCELEFDARGRVSRSQGQLEWLPWQPWP
CCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEEEECCCCCC
FASEPPAGLYFCEPAPELEQHLAKRYRPELETMTQRIVTHLAGPLHHQRLPDANLPAGSQ
CCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCC
VAPLVAHAMLIGAREQVGQVDFALHNAGGVRCSLEPGPLSEADIAGRLLPFAIPLTLYRV
HHHHHHHHHHHHCHHHHCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEH
HGHELAEALEGAIDNATNNGVTGNGNGSFPYTAGMRFCYQADRPKGARITRLEWESAPGC
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCCEEEEEECCCCCCC
WQPVEADAIYRGVSSAYTASGKEGYTALARTLTQHNQELGITLADAFIRWARYLPELATL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHH
PELVEYHGPHAMP
HHHHHHCCCCCCC
>Mature Secondary Structure 
SITVQLAHFSDCHSHFDGAPMRFFPVGESEWRTPCGGYARILTRLTALRQQADAAGQTC
EEEEEECCHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LFLHGGDTFQGSLYFNRFKGRANADLLSLLRPDAMVIGNHEFDLGNGPLVEFLRQLDFPV
EEEECCCCEECCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCE
LAANLDSSQEPADTPLRLQGLPMLHDASRPWHKRVIDGVPFALLGITLPQMAAIANPDPH
EEECCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
TRFHGIDDTLTAAIGEIKAAGIHHIILLSHLGLEQDKRLAARFPELSLIIGGHTHSQLGD
CEECCCCHHHHHHHHHHHHCCHHHEEHHHHCCCCHHHHHHHCCCCEEEEECCCCHHHHHC
LAPLGLESDGSYPLMVNDVAILHAAHSALCLGVCELEFDARGRVSRSQGQLEWLPWQPWP
CCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCEEEECCCCCC
FASEPPAGLYFCEPAPELEQHLAKRYRPELETMTQRIVTHLAGPLHHQRLPDANLPAGSQ
CCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCC
VAPLVAHAMLIGAREQVGQVDFALHNAGGVRCSLEPGPLSEADIAGRLLPFAIPLTLYRV
HHHHHHHHHHHHCHHHHCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEH
HGHELAEALEGAIDNATNNGVTGNGNGSFPYTAGMRFCYQADRPKGARITRLEWESAPGC
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCCEEEEEECCCCCCC
WQPVEADAIYRGVSSAYTASGKEGYTALARTLTQHNQELGITLADAFIRWARYLPELATL
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHH
PELVEYHGPHAMP
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]