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The map label for this gene is nrfE [H]

Identifier: 145299281

GI number: 145299281

Start: 2465479

End: 2467428

Strand: Direct

Name: nrfE [H]

Synonym: ASA_2325

Alternate gene names: 145299281

Gene position: 2465479-2467428 (Clockwise)

Preceding gene: 145299280

Following gene: 145299282

Centisome position: 52.43

GC content: 64.51

Gene sequence:

>1950_bases
GTGCTGGCGGAGTTCGGCTATCTCTCACTGTTGCTGGCAACGGCGCTCTCTCTGGTGCAAGGCACCCTGCCCTGGCTGGG
CCTGAGGCTGGCATCGCCCCCTCTGCTGGGCTGTGCCAAGCCGCTGGCACTGCTCAATGCCGCCCTGCTGGGGGCTGCCC
TGCTGCTGCTCGCCAGCTGCTTTGCCCGGGATGATTTTACCGTCAGTTATGTGGCTCAGCACGCCAACAGCGCCCTGACC
ATGGGCTTCAAGCTGGCGGCGGTCTGGGGCGGCCATGAAGGCTCCATGCTCTTCTTCGTGTTTGCGCTGGCGCTCTGGGG
CGCCCTGGTGGCGCTCTGCTCGCAGCAGGTCGACTCGCTGATCCGTGCCCGGGTGCTCGCCATCATGGGGCTGATAGTGG
GGCTGTTTGGACTCTATACCCTTGTCTTCTCCAGCCCGTTTGACCGGCAGTTCCCGGGGCCCCTGGAGGGACGCGATCTC
AATCCCATGTTGCAGGACATAGGCCTCATCATTCACCCGCCCCTGCTCTATCTCGGCTACGTGGGCTTTGCAGTCAACTT
CGCCTTCGCCATGGCGGCGCTGCACTCGGGCAGGCTGGACGGCGCCGTGGCCCACTGGAGCAGACCCTGGGCGCTGGGCT
CCTGGGTGTTTCTCACCGCCGGTATCCTGCTCGGCTCCTGGTGGGCCTATTACGAGCTCGGCTGGGGTGGCTGGTGGTTC
TGGGATCCGGTGGAAAACGCCTCCCTGCTGCCCTGGCTGCTCGGCACAGCCCTGCTGCATGCCCTCATCGTCTGCGAGAA
GCGCGGCGCTTACGGCCACGGCGTGCTGCTGCTCTCCATCTTCACCTTCGCCCTGAGCCTGCTCGGCACCTTCGTGGTGC
GCTCCGGCGTGCTCACCTCGGTGCACGCCTTCGCGGTGGATCCCAATCGCGGCCTCACCCTCTTGCTGCTGCTCGGCCTG
TTATTGACCACGGCGCTCACCCTGTTTGCGCTGCGGGCAGATACCCGCGCCCCCTACGCCCGCTTCGGCTTCTGGTCAAA
AGAGGGACTCTTGGGCGCCGCCATCCTTCTGCTCAGCGTGGCCTGCGCCTGCGTGTTGCTCGGCACCTTCTACCCCATGG
TGTTCCAGTCCCTGCACCTGGGCTCGCTCTCGGTCGGTGCGCCATATTTCAACGCTGTTTTCGTACCCCTGGCCCTGGCC
CTGATGGCACTGATGACCCAGATCCCGCGCCTGCGCTGGCAATGTCTTGCGGCCAGCCCCCCCATCAAACGGATAGTGCC
GCCTCTGCTAGGTCTGCTCGGGGGCGGCCTGCTTAGCCTGGGGTATCGCGATCTTGGCGCCCTCAGTTGGGTTGGCCTTG
TCGCCAACGTGCTGAGTCTCTGGCTGGTGGCAAGCCTGTTGCTCAATTTCTCATTCAAGACCCATGGCCTGAGTGCCAAC
CGGCTGGGGAGTTTGCTCGCCCACCTGGGAGTCGCCATATGTGCCCTTGGCATCAATCAGGTGAGCCACTACAGCCAGGA
GGGGGGCACAGTATTAAAAGCGGGCAGCCCCTACCAGCTTGGCGCCTATACCTTTCGCTATGAGGGGAGCGAGCCCCTGC
TCGGCCCCAACTACACTGCCGAGCGCATTACGCTGAGCGTGCACAAAGGCGCCAAGGAGGTGGCGCGGTTGATGCCGGAG
CGGCACCACTACAGCGTACGCACCATGAACATGAACGAGCCCGGCATCCAGTGGGGTCTGTTTGGGGATCTCTACGTGGT
GCTCGGCGAGAAGATGGAGCCGGACGCCTACGCCATGCGCCTTCACTACAAGCCGCTGGTGCGCTGGATCTGGCTGGGGG
GCATGCTGATGATGGCAGGAGGTGCCCTGCGTTTGTCCAGGCGCAAGCCGTTGCTGGTATCCCGTCCAGCCAAGATCCCG
CAGCCCCTGCGCGAACAGGAGGCACCATGA

Upstream 100 bases:

>100_bases
CTTGTCTGTTTTAAGCGAATTGTTTTCTGGTCATGCCCCAACGCCCGCCTGCTGCGGACGCTGCGGCATAACATGAACCC
ATGATGGAACCGGAGGTTGT

Downstream 100 bases:

>100_bases
GCCCGCGCCTGCGTCTTTTTCTCCCCTTGCTGCTGACTCTGGGCCTCGGCACCCTGCTTTGGCTGGGGCTTGCCAACAAT
CCCTACCGCCAGGACGAGGC

Product: cytochrome c-type biogenesis protein NrfE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MLAEFGYLSLLLATALSLVQGTLPWLGLRLASPPLLGCAKPLALLNAALLGAALLLLASCFARDDFTVSYVAQHANSALT
MGFKLAAVWGGHEGSMLFFVFALALWGALVALCSQQVDSLIRARVLAIMGLIVGLFGLYTLVFSSPFDRQFPGPLEGRDL
NPMLQDIGLIIHPPLLYLGYVGFAVNFAFAMAALHSGRLDGAVAHWSRPWALGSWVFLTAGILLGSWWAYYELGWGGWWF
WDPVENASLLPWLLGTALLHALIVCEKRGAYGHGVLLLSIFTFALSLLGTFVVRSGVLTSVHAFAVDPNRGLTLLLLLGL
LLTTALTLFALRADTRAPYARFGFWSKEGLLGAAILLLSVACACVLLGTFYPMVFQSLHLGSLSVGAPYFNAVFVPLALA
LMALMTQIPRLRWQCLAASPPIKRIVPPLLGLLGGGLLSLGYRDLGALSWVGLVANVLSLWLVASLLLNFSFKTHGLSAN
RLGSLLAHLGVAICALGINQVSHYSQEGGTVLKAGSPYQLGAYTFRYEGSEPLLGPNYTAERITLSVHKGAKEVARLMPE
RHHYSVRTMNMNEPGIQWGLFGDLYVVLGEKMEPDAYAMRLHYKPLVRWIWLGGMLMMAGGALRLSRRKPLLVSRPAKIP
QPLREQEAP

Sequences:

>Translated_649_residues
MLAEFGYLSLLLATALSLVQGTLPWLGLRLASPPLLGCAKPLALLNAALLGAALLLLASCFARDDFTVSYVAQHANSALT
MGFKLAAVWGGHEGSMLFFVFALALWGALVALCSQQVDSLIRARVLAIMGLIVGLFGLYTLVFSSPFDRQFPGPLEGRDL
NPMLQDIGLIIHPPLLYLGYVGFAVNFAFAMAALHSGRLDGAVAHWSRPWALGSWVFLTAGILLGSWWAYYELGWGGWWF
WDPVENASLLPWLLGTALLHALIVCEKRGAYGHGVLLLSIFTFALSLLGTFVVRSGVLTSVHAFAVDPNRGLTLLLLLGL
LLTTALTLFALRADTRAPYARFGFWSKEGLLGAAILLLSVACACVLLGTFYPMVFQSLHLGSLSVGAPYFNAVFVPLALA
LMALMTQIPRLRWQCLAASPPIKRIVPPLLGLLGGGLLSLGYRDLGALSWVGLVANVLSLWLVASLLLNFSFKTHGLSAN
RLGSLLAHLGVAICALGINQVSHYSQEGGTVLKAGSPYQLGAYTFRYEGSEPLLGPNYTAERITLSVHKGAKEVARLMPE
RHHYSVRTMNMNEPGIQWGLFGDLYVVLGEKMEPDAYAMRLHYKPLVRWIWLGGMLMMAGGALRLSRRKPLLVSRPAKIP
QPLREQEAP
>Mature_649_residues
MLAEFGYLSLLLATALSLVQGTLPWLGLRLASPPLLGCAKPLALLNAALLGAALLLLASCFARDDFTVSYVAQHANSALT
MGFKLAAVWGGHEGSMLFFVFALALWGALVALCSQQVDSLIRARVLAIMGLIVGLFGLYTLVFSSPFDRQFPGPLEGRDL
NPMLQDIGLIIHPPLLYLGYVGFAVNFAFAMAALHSGRLDGAVAHWSRPWALGSWVFLTAGILLGSWWAYYELGWGGWWF
WDPVENASLLPWLLGTALLHALIVCEKRGAYGHGVLLLSIFTFALSLLGTFVVRSGVLTSVHAFAVDPNRGLTLLLLLGL
LLTTALTLFALRADTRAPYARFGFWSKEGLLGAAILLLSVACACVLLGTFYPMVFQSLHLGSLSVGAPYFNAVFVPLALA
LMALMTQIPRLRWQCLAASPPIKRIVPPLLGLLGGGLLSLGYRDLGALSWVGLVANVLSLWLVASLLLNFSFKTHGLSAN
RLGSLLAHLGVAICALGINQVSHYSQEGGTVLKAGSPYQLGAYTFRYEGSEPLLGPNYTAERITLSVHKGAKEVARLMPE
RHHYSVRTMNMNEPGIQWGLFGDLYVVLGEKMEPDAYAMRLHYKPLVRWIWLGGMLMMAGGALRLSRRKPLLVSRPAKIP
QPLREQEAP

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=636, Percent_Identity=42.2955974842767, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1790511, Length=574, Percent_Identity=42.8571428571429, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568
- InterPro:   IPR003570
- InterPro:   IPR017563 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70386; Mature: 70386

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEFGYLSLLLATALSLVQGTLPWLGLRLASPPLLGCAKPLALLNAALLGAALLLLASC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FARDDFTVSYVAQHANSALTMGFKLAAVWGGHEGSMLFFVFALALWGALVALCSQQVDSL
HCCCCCHHHHHHHHCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRARVLAIMGLIVGLFGLYTLVFSSPFDRQFPGPLEGRDLNPMLQDIGLIIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVNFAFAMAALHSGRLDGAVAHWSRPWALGSWVFLTAGILLGSWWAYYELGWGGWWF
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCEEE
WDPVENASLLPWLLGTALLHALIVCEKRGAYGHGVLLLSIFTFALSLLGTFVVRSGVLTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAVDPNRGLTLLLLLGLLLTTALTLFALRADTRAPYARFGFWSKEGLLGAAILLLSV
HHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHH
ACACVLLGTFYPMVFQSLHLGSLSVGAPYFNAVFVPLALALMALMTQIPRLRWQCLAASP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PIKRIVPPLLGLLGGGLLSLGYRDLGALSWVGLVANVLSLWLVASLLLNFSFKTHGLSAN
CHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RLGSLLAHLGVAICALGINQVSHYSQEGGTVLKAGSPYQLGAYTFRYEGSEPLLGPNYTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCEEEEECCCCCCCCCCCCH
ERITLSVHKGAKEVARLMPERHHYSVRTMNMNEPGIQWGLFGDLYVVLGEKMEPDAYAMR
HHEEEEHHCCHHHHHHHCCCCCCCEEEEECCCCCCCEECHHHHHHHHHCCCCCCCHHHHE
LHYKPLVRWIWLGGMLMMAGGALRLSRRKPLLVSRPAKIPQPLREQEAP
EHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCCCCCHHHCCCC
>Mature Secondary Structure
MLAEFGYLSLLLATALSLVQGTLPWLGLRLASPPLLGCAKPLALLNAALLGAALLLLASC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FARDDFTVSYVAQHANSALTMGFKLAAVWGGHEGSMLFFVFALALWGALVALCSQQVDSL
HCCCCCHHHHHHHHCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRARVLAIMGLIVGLFGLYTLVFSSPFDRQFPGPLEGRDLNPMLQDIGLIIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVNFAFAMAALHSGRLDGAVAHWSRPWALGSWVFLTAGILLGSWWAYYELGWGGWWF
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHEEECCCCEEE
WDPVENASLLPWLLGTALLHALIVCEKRGAYGHGVLLLSIFTFALSLLGTFVVRSGVLTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHAFAVDPNRGLTLLLLLGLLLTTALTLFALRADTRAPYARFGFWSKEGLLGAAILLLSV
HHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHH
ACACVLLGTFYPMVFQSLHLGSLSVGAPYFNAVFVPLALALMALMTQIPRLRWQCLAASP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PIKRIVPPLLGLLGGGLLSLGYRDLGALSWVGLVANVLSLWLVASLLLNFSFKTHGLSAN
CHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
RLGSLLAHLGVAICALGINQVSHYSQEGGTVLKAGSPYQLGAYTFRYEGSEPLLGPNYTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCEEEEECCCCCCCCCCCCH
ERITLSVHKGAKEVARLMPERHHYSVRTMNMNEPGIQWGLFGDLYVVLGEKMEPDAYAMR
HHEEEEHHCCHHHHHHHCCCCCCCEEEEECCCCCCCEECHHHHHHHHHCCCCCCCHHHHE
LHYKPLVRWIWLGGMLMMAGGALRLSRRKPLLVSRPAKIPQPLREQEAP
EHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]