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The map label for this gene is nudL [H]

Identifier: 145299251

GI number: 145299251

Start: 2424480

End: 2425046

Strand: Direct

Name: nudL [H]

Synonym: ASA_2294

Alternate gene names: 145299251

Gene position: 2424480-2425046 (Clockwise)

Preceding gene: 145299250

Following gene: 145299252

Centisome position: 51.56

GC content: 60.49

Gene sequence:

>567_bases
ATGGACCGCGCCGAACTGCTGACCCGCTTTTTACTGCAACGCCCTGCCCCCGCCCATCGACTGACGGTGACAGGGCTCAA
ACCTGCCGCCGTCTTGCTGCCGCTGGTGGAGCGGGCCGACGGCTTGCAACTGCTGCTGACCCGCCGCAGCGCACACCTGC
GTCATCACGCGGGACAGATTAGCTTTCCTGGCGGGCGACAGGATCCGGACGATCACAACCGGATCCATACGGCATTGCGG
GAAACCTGGGAGGAGCTGGGTATCATACCGGCTCAGGTCGAGATCATCGGGACCCTGGCCCCGCTCAACACCATTTCCCA
ATACGATGTGCTACCCGTGCTGGGGCTGGTTGCCGCCGATTATCAACTCACCTTGAGCCAGGATGAAGTGGCTCAGGCCT
TTGAAGTACCACTCCATCATCTGCTGGACCCACGCCACCACATAGCCATGACCATTCCAAGGGCCGATCAGCTACACACC
ATCTACTGGATACCTTGGCAGGATCACTTCATCTGGGGGGCGACTGCCAGCATGATCCGCCAGCTATCTCGCCAACTTGC
CACGTAA

Upstream 100 bases:

>100_bases
GAGAAGTTGAGAAGTTGAGAAGTTGACAGAATGGATAACGGAGTGACCATGAAAGAGACCCCAGCGCAGGATTGAGAGAC
GATTCGAGAGAATAAACAAG

Downstream 100 bases:

>100_bases
CATTTTGCAAACATATTCCAGTGCAATATTTGCGCGCTAACAATAAACTAACGTATAGGTTTATAAAAAAAATTGATTTT
TTATTCTTTCGATCACATTT

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MDRAELLTRFLLQRPAPAHRLTVTGLKPAAVLLPLVERADGLQLLLTRRSAHLRHHAGQISFPGGRQDPDDHNRIHTALR
ETWEELGIIPAQVEIIGTLAPLNTISQYDVLPVLGLVAADYQLTLSQDEVAQAFEVPLHHLLDPRHHIAMTIPRADQLHT
IYWIPWQDHFIWGATASMIRQLSRQLAT

Sequences:

>Translated_188_residues
MDRAELLTRFLLQRPAPAHRLTVTGLKPAAVLLPLVERADGLQLLLTRRSAHLRHHAGQISFPGGRQDPDDHNRIHTALR
ETWEELGIIPAQVEIIGTLAPLNTISQYDVLPVLGLVAADYQLTLSQDEVAQAFEVPLHHLLDPRHHIAMTIPRADQLHT
IYWIPWQDHFIWGATASMIRQLSRQLAT
>Mature_188_residues
MDRAELLTRFLLQRPAPAHRLTVTGLKPAAVLLPLVERADGLQLLLTRRSAHLRHHAGQISFPGGRQDPDDHNRIHTALR
ETWEELGIIPAQVEIIGTLAPLNTISQYDVLPVLGLVAADYQLTLSQDEVAQAFEVPLHHLLDPRHHIAMTIPRADQLHT
IYWIPWQDHFIWGATASMIRQLSRQLAT

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=118, Percent_Identity=41.5254237288136, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI32469515, Length=91, Percent_Identity=45.0549450549451, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1788115, Length=185, Percent_Identity=42.1621621621622, Blast_Score=116, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17536993, Length=117, Percent_Identity=39.3162393162393, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17510677, Length=185, Percent_Identity=29.7297297297297, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI18859683, Length=158, Percent_Identity=37.9746835443038, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 21224; Mature: 21224

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01293 UPF0035

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAELLTRFLLQRPAPAHRLTVTGLKPAAVLLPLVERADGLQLLLTRRSAHLRHHAGQI
CCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SFPGGRQDPDDHNRIHTALRETWEELGIIPAQVEIIGTLAPLNTISQYDVLPVLGLVAAD
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHCHHHHHHHHHHHHHHHHHCC
YQLTLSQDEVAQAFEVPLHHLLDPRHHIAMTIPRADQLHTIYWIPWQDHFIWGATASMIR
CEEEECHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCEEEEEEECCCCCEEEHHHHHHHH
QLSRQLAT
HHHHHHCC
>Mature Secondary Structure
MDRAELLTRFLLQRPAPAHRLTVTGLKPAAVLLPLVERADGLQLLLTRRSAHLRHHAGQI
CCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SFPGGRQDPDDHNRIHTALRETWEELGIIPAQVEIIGTLAPLNTISQYDVLPVLGLVAAD
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHCHHHHHHHHHHHHHHHHHCC
YQLTLSQDEVAQAFEVPLHHLLDPRHHIAMTIPRADQLHTIYWIPWQDHFIWGATASMIR
CEEEECHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCEEEEEEECCCCCEEEHHHHHHHH
QLSRQLAT
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA