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The map label for this gene is sdaC [H]

Identifier: 145299252

GI number: 145299252

Start: 2425262

End: 2426560

Strand: Direct

Name: sdaC [H]

Synonym: ASA_2295

Alternate gene names: 145299252

Gene position: 2425262-2426560 (Clockwise)

Preceding gene: 145299251

Following gene: 145299254

Centisome position: 51.57

GC content: 55.81

Gene sequence:

>1299_bases
ATGTCTAATACAGTCATAGGCGCACAGGAAGTTGCAGCCTCACAGGAGCAAGGAACGAGCTCAATCCAATCTCGCGGTTG
GAGCAAACAAGACACTACCTGGGTTATCAGCCTGTTCGGCACTGCCGTCGGCGCGGGTATCCTGTTCCTGCCCATCAACG
CTGGCATGGGTGGCTTCTGGCCACTGGTGGTCATGGCGCTGCTGGTCGGCCCCATGACTTATCTGGCCCACCGTGGCCTC
GCCCGTTTTGTACTTTCGTCCAAGCAACCCAATGCCGATATCACACAAGTGGTGGAAGAGCATTTCGGGGTGGGCGCCGG
TAAATTAATCACCCTGCTCTACTTCTTTGCCATCTACCCCATAGTGCTGATCTACGGTGTCGGTATCACCAACACGGTCG
AAAGCTTCATGGTCAACCAGTTGCAGATGGTTGCGCCACCGCGCTGGCTCCTCTCCATCGTGCTGATCATGGGCATGATG
TCGGTGATGCTGGCGGGCGAGAAGCTGATGCTGAAGGTCACCGAGTTTCTGGTCTACCCGCTCATCGCCATCCTGGTAGG
TATCTCCTTCTACCTGATCCCCGACTGGACTGGCGCCGCCCTGTCCCAGGTGCCGTCTGCCAAGGATTTCGCCACTACCT
TGTGGCTGACCATCCCGGTACTGGTGTTCTCCTTCAACCACAGCCCGGCCATCTCCAGCTTCTCTCTGGCCCAGCGTCGT
GATCATGGCGACCATGCAGTCGAGAAGTCCGATGCCATTCTCAAGCGCACTGCCACCATACTGCTGGGCTTCGTGATGTT
CTTCGTCTTCTCCTGTGTCATGAGCCTGACCCCGGAACAACTGACTGAAGCCAAGTCACAGAATATTGCCGTGCTCTCTT
ATCTGGCAAACCAGCATGCAAGCCCCATCATCTCTTACTTCGGTCCGCTGGTTGCATTCGTCGCCATCGTATCCTCCTTC
TTTGGTCACTACCTGGGTGCCCGTGAAGGTCTGAAAGGGATGATCGTCCAGAACATGCGCAAATCCGGCAAAGAGCCGAA
CCACAAGAAGGTTGAGATCTTCATCATCGCCTTCTTCATCCTCACCCTGTGGGGCACGGCCATCGCCAACCCCTCCATCC
TGGGCATGATTGAATCTCTTGGTGGCCCCATCATCGCCACCATCCTCTTCATCATGCCGATGTACGCCATCAAACGCGTA
CCAGCCATGGCAAAATACCAGGGACACATCAGCAACGCGTTTGTTGCTCTGATGGGTACCATTGCCATCTCCGCCATCCT
TTACCAGCTGTTTGGCTAA

Upstream 100 bases:

>100_bases
GGTTTATCCCTCACAAAGGTGAATTTGATTAACATTTTTGATTAGAAAAACCGTATCCTTGCGCCGACTCAACAAAAAAC
ACACATTCGGGGTGAGACAC

Downstream 100 bases:

>100_bases
TCACCAGACCATAACGGCAAAGCAAATGCCCGCCAGTGATGGCGGGCATTTTTTATGCACAAATAACCCATTCCTGTAAT
GCTAAACTGCACTCTTCAGT

Product: serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSNTVIGAQEVAASQEQGTSSIQSRGWSKQDTTWVISLFGTAVGAGILFLPINAGMGGFWPLVVMALLVGPMTYLAHRGL
ARFVLSSKQPNADITQVVEEHFGVGAGKLITLLYFFAIYPIVLIYGVGITNTVESFMVNQLQMVAPPRWLLSIVLIMGMM
SVMLAGEKLMLKVTEFLVYPLIAILVGISFYLIPDWTGAALSQVPSAKDFATTLWLTIPVLVFSFNHSPAISSFSLAQRR
DHGDHAVEKSDAILKRTATILLGFVMFFVFSCVMSLTPEQLTEAKSQNIAVLSYLANQHASPIISYFGPLVAFVAIVSSF
FGHYLGAREGLKGMIVQNMRKSGKEPNHKKVEIFIIAFFILTLWGTAIANPSILGMIESLGGPIIATILFIMPMYAIKRV
PAMAKYQGHISNAFVALMGTIAISAILYQLFG

Sequences:

>Translated_432_residues
MSNTVIGAQEVAASQEQGTSSIQSRGWSKQDTTWVISLFGTAVGAGILFLPINAGMGGFWPLVVMALLVGPMTYLAHRGL
ARFVLSSKQPNADITQVVEEHFGVGAGKLITLLYFFAIYPIVLIYGVGITNTVESFMVNQLQMVAPPRWLLSIVLIMGMM
SVMLAGEKLMLKVTEFLVYPLIAILVGISFYLIPDWTGAALSQVPSAKDFATTLWLTIPVLVFSFNHSPAISSFSLAQRR
DHGDHAVEKSDAILKRTATILLGFVMFFVFSCVMSLTPEQLTEAKSQNIAVLSYLANQHASPIISYFGPLVAFVAIVSSF
FGHYLGAREGLKGMIVQNMRKSGKEPNHKKVEIFIIAFFILTLWGTAIANPSILGMIESLGGPIIATILFIMPMYAIKRV
PAMAKYQGHISNAFVALMGTIAISAILYQLFG
>Mature_431_residues
SNTVIGAQEVAASQEQGTSSIQSRGWSKQDTTWVISLFGTAVGAGILFLPINAGMGGFWPLVVMALLVGPMTYLAHRGLA
RFVLSSKQPNADITQVVEEHFGVGAGKLITLLYFFAIYPIVLIYGVGITNTVESFMVNQLQMVAPPRWLLSIVLIMGMMS
VMLAGEKLMLKVTEFLVYPLIAILVGISFYLIPDWTGAALSQVPSAKDFATTLWLTIPVLVFSFNHSPAISSFSLAQRRD
HGDHAVEKSDAILKRTATILLGFVMFFVFSCVMSLTPEQLTEAKSQNIAVLSYLANQHASPIISYFGPLVAFVAIVSSFF
GHYLGAREGLKGMIVQNMRKSGKEPNHKKVEIFIIAFFILTLWGTAIANPSILGMIESLGGPIIATILFIMPMYAIKRVP
AMAKYQGHISNAFVALMGTIAISAILYQLFG

Specific function: Involved in the import of serine into the cell [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=425, Percent_Identity=57.4117647058823, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1789504, Length=443, Percent_Identity=43.3408577878104, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1789211, Length=409, Percent_Identity=35.4523227383863, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1789961, Length=394, Percent_Identity=26.3959390862944, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI145693183, Length=415, Percent_Identity=25.3012048192771, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46986; Mature: 46855

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTVIGAQEVAASQEQGTSSIQSRGWSKQDTTWVISLFGTAVGAGILFLPINAGMGGFW
CCCCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHH
PLVVMALLVGPMTYLAHRGLARFVLSSKQPNADITQVVEEHFGVGAGKLITLLYFFAIYP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IVLIYGVGITNTVESFMVNQLQMVAPPRWLLSIVLIMGMMSVMLAGEKLMLKVTEFLVYP
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LIAILVGISFYLIPDWTGAALSQVPSAKDFATTLWLTIPVLVFSFNHSPAISSFSLAQRR
HHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DHGDHAVEKSDAILKRTATILLGFVMFFVFSCVMSLTPEQLTEAKSQNIAVLSYLANQHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCC
SPIISYFGPLVAFVAIVSSFFGHYLGAREGLKGMIVQNMRKSGKEPNHKKVEIFIIAFFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LTLWGTAIANPSILGMIESLGGPIIATILFIMPMYAIKRVPAMAKYQGHISNAFVALMGT
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IAISAILYQLFG
HHHHHHHHHHHC
>Mature Secondary Structure 
SNTVIGAQEVAASQEQGTSSIQSRGWSKQDTTWVISLFGTAVGAGILFLPINAGMGGFW
CCCCCCHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHH
PLVVMALLVGPMTYLAHRGLARFVLSSKQPNADITQVVEEHFGVGAGKLITLLYFFAIYP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IVLIYGVGITNTVESFMVNQLQMVAPPRWLLSIVLIMGMMSVMLAGEKLMLKVTEFLVYP
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LIAILVGISFYLIPDWTGAALSQVPSAKDFATTLWLTIPVLVFSFNHSPAISSFSLAQRR
HHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DHGDHAVEKSDAILKRTATILLGFVMFFVFSCVMSLTPEQLTEAKSQNIAVLSYLANQHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHCCC
SPIISYFGPLVAFVAIVSSFFGHYLGAREGLKGMIVQNMRKSGKEPNHKKVEIFIIAFFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LTLWGTAIANPSILGMIESLGGPIIATILFIMPMYAIKRVPAMAKYQGHISNAFVALMGT
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IAISAILYQLFG
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]