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The map label for this gene is cbrB [H]

Identifier: 145296829

GI number: 145296829

Start: 3023201

End: 3024181

Strand: Direct

Name: cbrB [H]

Synonym: cgR_2731

Alternate gene names: 145296829

Gene position: 3023201-3024181 (Clockwise)

Preceding gene: 145296828

Following gene: 145296830

Centisome position: 91.22

GC content: 52.7

Gene sequence:

>981_bases
TTGCTTATTGTCCTTGCTGTGGCCATCTTGCCGCTGATGGCGCTGAGTCTTTTCATTGGTTCGAGAATCATAGCCCCCTC
TGTTGTTGTGGAGGGACTCACTCATTTTGATCCCACCAACAATGATCATTTGGTGCTTCGTGAATTGAGAATCCCCCGCA
CCATCATCGCTGTTGTGGCAGGTGCAGCGCTTGGTTTAGCGGGCACTTTGATGCAGTCACTGACCAGGAACGCACTCGCG
GAACCAGGCACTTTAGGCGTTAATGCCGGTGCCGCGGCTGGTGTGGTGATTGGCTTGACGTTCTTTTCTACAAGCTCCAT
CAACATCTACATTTGGTTCGCGTTCATAGGTGCTGGCATCGCATCGGTGTTGGTGCACCGGTTGGGTCGATCTGGTGAAA
CTGGTGTGAACCCGGTTCGTCTGGTGCTTGCAGGTGCGGGACTGTCGATTATGGTTTCATCCATCACCACCATGTTGGTG
TTGAGCTCTACCGATAAGGTTTTTACAGCTCTTCGGGCATGGGCAACTGGATCATTGGATGGGCGTGGATGGGAGTCGTT
GCCTGCCGTGGCTTTGTCACTTCTTGCATGCGTTATCCTCTGCGCATACCTTGCGGGATCGTTGAATTCTGTGACCTTGG
GCCAAGATTTGGCAACCTCTTTGGGCGTTAATATTCGACGCACCTGGTTGCTCACCAATGTGGGAATTTTGATCCTCGCG
GGTGGTGCAACTGCTGCCGTGGGACCCATCGGTTTTGTGGGACTAGCGGCACCGCATATTGCTCGCACGTTGGCAGGGCC
CGATCACAAATGGTTGCTACCCTACTCTGCTGTGATTGCCGGGTTGGTGTTGTTGAGCGCAGACATAATTGGTCGAGTCA
TTATCTTCCCTGCAGAAATTGGTGCTGGAATCATGACTGCTTTTATCGGCGCTCCGTTTTTCATCTGGCTTGTCAGACGA
GGAAAGGTGTCCGGCTTATGA

Upstream 100 bases:

>100_bases
CGTCGTTGAAGCACTGGGTAAGTAAAACCCAGTGTCTGTAGCAACAACACAAAAAACGCCACCTGTAGCCGGCAAGGTAT
CTTTCAGGTGGCGTTTGCCA

Downstream 100 bases:

>100_bases
CCATGCGGGTGGCCTTGGGAAGGGTGCAGGTTTTCGTCGAAAAGCGAACTGCCCTGCTGGCACTTGCCCTGTGCCTGGCT
GCGGCGGCGCTGGCCGTCTA

Product: hypothetical protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLIVLAVAILPLMALSLFIGSRIIAPSVVVEGLTHFDPTNNDHLVLRELRIPRTIIAVVAGAALGLAGTLMQSLTRNALA
EPGTLGVNAGAAAGVVIGLTFFSTSSINIYIWFAFIGAGIASVLVHRLGRSGETGVNPVRLVLAGAGLSIMVSSITTMLV
LSSTDKVFTALRAWATGSLDGRGWESLPAVALSLLACVILCAYLAGSLNSVTLGQDLATSLGVNIRRTWLLTNVGILILA
GGATAAVGPIGFVGLAAPHIARTLAGPDHKWLLPYSAVIAGLVLLSADIIGRVIIFPAEIGAGIMTAFIGAPFFIWLVRR
GKVSGL

Sequences:

>Translated_326_residues
MLIVLAVAILPLMALSLFIGSRIIAPSVVVEGLTHFDPTNNDHLVLRELRIPRTIIAVVAGAALGLAGTLMQSLTRNALA
EPGTLGVNAGAAAGVVIGLTFFSTSSINIYIWFAFIGAGIASVLVHRLGRSGETGVNPVRLVLAGAGLSIMVSSITTMLV
LSSTDKVFTALRAWATGSLDGRGWESLPAVALSLLACVILCAYLAGSLNSVTLGQDLATSLGVNIRRTWLLTNVGILILA
GGATAAVGPIGFVGLAAPHIARTLAGPDHKWLLPYSAVIAGLVLLSADIIGRVIIFPAEIGAGIMTAFIGAPFFIWLVRR
GKVSGL
>Mature_326_residues
MLIVLAVAILPLMALSLFIGSRIIAPSVVVEGLTHFDPTNNDHLVLRELRIPRTIIAVVAGAALGLAGTLMQSLTRNALA
EPGTLGVNAGAAAGVVIGLTFFSTSSINIYIWFAFIGAGIASVLVHRLGRSGETGVNPVRLVLAGAGLSIMVSSITTMLV
LSSTDKVFTALRAWATGSLDGRGWESLPAVALSLLACVILCAYLAGSLNSVTLGQDLATSLGVNIRRTWLLTNVGILILA
GGATAAVGPIGFVGLAAPHIARTLAGPDHKWLLPYSAVIAGLVLLSADIIGRVIIFPAEIGAGIMTAFIGAPFFIWLVRR
GKVSGL

Specific function: Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=310, Percent_Identity=44.8387096774194, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790740, Length=291, Percent_Identity=36.426116838488, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790741, Length=284, Percent_Identity=35.2112676056338, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=35.6890459363958, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786804, Length=281, Percent_Identity=33.8078291814947, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=33.5664335664336, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33570; Mature: 33570

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVLAVAILPLMALSLFIGSRIIAPSVVVEGLTHFDPTNNDHLVLRELRIPRTIIAVVA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHH
GAALGLAGTLMQSLTRNALAEPGTLGVNAGAAAGVVIGLTFFSTSSINIYIWFAFIGAGI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEEEEECCCCEEEEHHHHHHHHH
ASVLVHRLGRSGETGVNPVRLVLAGAGLSIMVSSITTMLVLSSTDKVFTALRAWATGSLD
HHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GRGWESLPAVALSLLACVILCAYLAGSLNSVTLGQDLATSLGVNIRRTWLLTNVGILILA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHCCCHHEEHHEECCCEEEEE
GGATAAVGPIGFVGLAAPHIARTLAGPDHKWLLPYSAVIAGLVLLSADIIGRVIIFPAEI
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCEEEEEECHH
GAGIMTAFIGAPFFIWLVRRGKVSGL
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLIVLAVAILPLMALSLFIGSRIIAPSVVVEGLTHFDPTNNDHLVLRELRIPRTIIAVVA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHH
GAALGLAGTLMQSLTRNALAEPGTLGVNAGAAAGVVIGLTFFSTSSINIYIWFAFIGAGI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEEEEEEECCCCEEEEHHHHHHHHH
ASVLVHRLGRSGETGVNPVRLVLAGAGLSIMVSSITTMLVLSSTDKVFTALRAWATGSLD
HHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
GRGWESLPAVALSLLACVILCAYLAGSLNSVTLGQDLATSLGVNIRRTWLLTNVGILILA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHCCCHHEEHHEECCCEEEEE
GGATAAVGPIGFVGLAAPHIARTLAGPDHKWLLPYSAVIAGLVLLSADIIGRVIIFPAEI
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCEEEEEECHH
GAGIMTAFIGAPFFIWLVRRGKVSGL
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8596459 [H]