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The map label for this gene is fepB [H]

Identifier: 145296828

GI number: 145296828

Start: 3022100

End: 3023125

Strand: Direct

Name: fepB [H]

Synonym: cgR_2730

Alternate gene names: 145296828

Gene position: 3022100-3023125 (Clockwise)

Preceding gene: 145296825

Following gene: 145296829

Centisome position: 91.19

GC content: 54.78

Gene sequence:

>1026_bases
GTGCGTGCACTAACCAAGAAGTTTCTCACTGCCATCACCACCGGATCACTAGCTTTTACTGCAGTTGCCTGCTCAAACGA
TGATTCTTCCACCACTGAATCATCCACAACTTCTGCCTCAAGCTCTGCATCTGCAGAAGAAAACACCGTTGAGTGGCCAC
GCACCATCACTCACGAACTTGGCGAAACTGTGATCGAAGAAAAACCTGAACGCATCGCCAACACCGCACTTTCCGTCACC
GGAACCCTGCTTGCCATCGACGCTCCCCTGATCGCATCCGCAGCAACCAACCCAAGCGAAATCACCGACGATCAGGGATT
CTTCTCCCAGTGGTCCGATGAGGCTGAAGCAGCCGGCGTGGAAGTTCTCTACCCAGGCCTTCAATTCGATATGGAATCCC
TCATCGCGCAGGACCCTGACCTGGTGATTATCTCCATCGCAGGTGCCGACTCCGTTGCCGATGAATACGAGCAGATCTCC
GCGCAGTTCCCCACCATCGCAGTTGACTACTCCAAGCAGTCCTGGCAGGAACTAGCCACTGAGCTCGGCGAAGCACTTGG
CCTTGAGGAAGAAGCTGAAGCAGCAGTTGAAGAGTTCGACGCATATGTTGCCGATGCTGCCACCAAGATCAACGCACCAG
CAGGCGGCGTATCCGTTATTTCCTACAACGGCCCTGGTGAAACCCAAGGTGTTGCAAAGAAGGGCGGATCCCACGGTGAG
ATCTTCGCCAACCTGGGCATCGATGTTGTTGAAGCCCCAGCAGATCTAGACACCTCTGCTCAGGCACGCCAAGACTTCGC
TTTTGTCACCTACGAGAACCTCTCCCAGGCAGCAACCGGTGATGCGATCTTCATCCTGACCGGCACCGATGAGAACGCCG
AAGCACTGAAGGCCGATGCCACCTTGGCTAACCTTCCTGCAGTTCAAAACGGTGAAGTTTATGGTCTGGGTGAAACCTCA
TTCCGTGTGGACCCATACTCTGGTCGCCTGATCGTCGACACCGTCGTTGAAGCACTGGGTAAGTAA

Upstream 100 bases:

>100_bases
TAGATGAACCCAACTTTAGTTTGAGGCTTGCCTAACCTTAATCACCACTGCTAATGTTCTTTTCGTCAATAATTAGGCTA
ACCTAAATAGGGGAGTACGT

Downstream 100 bases:

>100_bases
AACCCAGTGTCTGTAGCAACAACACAAAAAACGCCACCTGTAGCCGGCAAGGTATCTTTCAGGTGGCGTTTGCCATTGCT
TATTGTCCTTGCTGTGGCCA

Product: iron-enterobactin transporter periplasmic binding protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRALTKKFLTAITTGSLAFTAVACSNDDSSTTESSTTSASSSASAEENTVEWPRTITHELGETVIEEKPERIANTALSVT
GTLLAIDAPLIASAATNPSEITDDQGFFSQWSDEAEAAGVEVLYPGLQFDMESLIAQDPDLVIISIAGADSVADEYEQIS
AQFPTIAVDYSKQSWQELATELGEALGLEEEAEAAVEEFDAYVADAATKINAPAGGVSVISYNGPGETQGVAKKGGSHGE
IFANLGIDVVEAPADLDTSAQARQDFAFVTYENLSQAATGDAIFILTGTDENAEALKADATLANLPAVQNGEVYGLGETS
FRVDPYSGRLIVDTVVEALGK

Sequences:

>Translated_341_residues
MRALTKKFLTAITTGSLAFTAVACSNDDSSTTESSTTSASSSASAEENTVEWPRTITHELGETVIEEKPERIANTALSVT
GTLLAIDAPLIASAATNPSEITDDQGFFSQWSDEAEAAGVEVLYPGLQFDMESLIAQDPDLVIISIAGADSVADEYEQIS
AQFPTIAVDYSKQSWQELATELGEALGLEEEAEAAVEEFDAYVADAATKINAPAGGVSVISYNGPGETQGVAKKGGSHGE
IFANLGIDVVEAPADLDTSAQARQDFAFVTYENLSQAATGDAIFILTGTDENAEALKADATLANLPAVQNGEVYGLGETS
FRVDPYSGRLIVDTVVEALGK
>Mature_341_residues
MRALTKKFLTAITTGSLAFTAVACSNDDSSTTESSTTSASSSASAEENTVEWPRTITHELGETVIEEKPERIANTALSVT
GTLLAIDAPLIASAATNPSEITDDQGFFSQWSDEAEAAGVEVLYPGLQFDMESLIAQDPDLVIISIAGADSVADEYEQIS
AQFPTIAVDYSKQSWQELATELGEALGLEEEAEAAVEEFDAYVADAATKINAPAGGVSVISYNGPGETQGVAKKGGSHGE
IFANLGIDVVEAPADLDTSAQARQDFAFVTYENLSQAATGDAIFILTGTDENAEALKADATLANLPAVQNGEVYGLGETS
FRVDPYSGRLIVDTVVEALGK

Specific function: Binds ferrienterobactin; part of the binding-protein- dependent transport system for uptake of ferrienterobactin [H]

COG id: COG4592

COG function: function code P; ABC-type Fe2+-enterobactin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786807, Length=288, Percent_Identity=38.5416666666667, Blast_Score=211, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 35668; Mature: 35668

Theoretical pI: Translated: 3.66; Mature: 3.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALTKKFLTAITTGSLAFTAVACSNDDSSTTESSTTSASSSASAEENTVEWPRTITHEL
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
GETVIEEKPERIANTALSVTGTLLAIDAPLIASAATNPSEITDDQGFFSQWSDEAEAAGV
HHHHHHHCHHHHHHHHHHHHEEEEEECCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCCE
EVLYPGLQFDMESLIAQDPDLVIISIAGADSVADEYEQISAQFPTIAVDYSKQSWQELAT
EEEECCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
ELGEALGLEEEAEAAVEEFDAYVADAATKINAPAGGVSVISYNGPGETQGVAKKGGSHGE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHCCCCCCE
IFANLGIDVVEAPADLDTSAQARQDFAFVTYENLSQAATGDAIFILTGTDENAEALKADA
EEEECCCEEEECCCCCCCCHHHHHCEEEEEHHHHHHHCCCCEEEEEECCCCCHHHHHHCC
TLANLPAVQNGEVYGLGETSFRVDPYSGRLIVDTVVEALGK
HHHHCCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRALTKKFLTAITTGSLAFTAVACSNDDSSTTESSTTSASSSASAEENTVEWPRTITHEL
CCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
GETVIEEKPERIANTALSVTGTLLAIDAPLIASAATNPSEITDDQGFFSQWSDEAEAAGV
HHHHHHHCHHHHHHHHHHHHEEEEEECCCHHHHCCCCCCCCCCCCCHHHHCCCHHHHCCE
EVLYPGLQFDMESLIAQDPDLVIISIAGADSVADEYEQISAQFPTIAVDYSKQSWQELAT
EEEECCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHH
ELGEALGLEEEAEAAVEEFDAYVADAATKINAPAGGVSVISYNGPGETQGVAKKGGSHGE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHCCCCCCE
IFANLGIDVVEAPADLDTSAQARQDFAFVTYENLSQAATGDAIFILTGTDENAEALKADA
EEEECCCEEEECCCCCCCCHHHHHCEEEEEHHHHHHHCCCCEEEEEECCCCCHHHHHHCC
TLANLPAVQNGEVYGLGETSFRVDPYSGRLIVDTVVEALGK
HHHHCCCCCCCCEEEECCCCEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]