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The map label for this gene is fepG [H]

Identifier: 145296830

GI number: 145296830

Start: 3024178

End: 3025200

Strand: Direct

Name: fepG [H]

Synonym: cgR_2732

Alternate gene names: 145296830

Gene position: 3024178-3025200 (Clockwise)

Preceding gene: 145296829

Following gene: 145296831

Centisome position: 91.25

GC content: 59.34

Gene sequence:

>1023_bases
ATGACCATGCGGGTGGCCTTGGGAAGGGTGCAGGTTTTCGTCGAAAAGCGAACTGCCCTGCTGGCACTTGCCCTGTGCCT
GGCTGCGGCGGCGCTGGCCGTCTACTCCGTGGCCAGTGGCACCATCAATTATTCGCTGGCCGAGGTGGCATCGGCGCTGG
CGCTGCGCGGGGAAGACAAAACTGAGCTGGTGATTTGGAGCATCCGATTGCCCAGAGCGGTGGCGGCGATCGCCGTCGGA
ATGGCCTTGGGCGCCGCGGGATCCGTGTTCCAATCGATCTCGCGGAACGCGCTCGGATCACCGGACGTCATCGGATTCAC
CACGGGAGCCGCTACCGGCGCGGTGTTGCAGATCGTGCTTTACAACAAAGGCGCGACCGCAACCGCACTATCGGCCGTTG
CATTCGGCGTGGTCACAGCGGTAATTGTGTACTTGCTTTCCCGGAATCGGGGCAGCACTGGCGGCTACCGGCTCGTGCTC
ATTGGCATCGGAGTATCCGCCATGCTCTCTGCGCTGAATACCTTGCTGCTTGCATGGGGCGATCTGGATCTGGCGGTGAA
AGCTCGGATTTGGCTGTCCGGTTCGCTGAACGCGCGTGAATGGAACGATGTTTATCCGGCACTTATTGCGCTGGCGATCT
GTCTGCCGATGCTGATTTATTACAGTCGGCCGCTCAATATTTTGGAAATGGGCGATGATCAAGCGAAACAGCTCGGTGTT
AATACAGAACGACTTAGGTTGATCGTGATGATTCTTGGCGTTCTGCTTACATCTGTTGCTGTTGCGGCCGCAGGTCCCAT
CGCATTCATCGCGCTGGCTGCGCCGCAAATCGTCTCCCGAATCACCGGTGCGGCGCGGGTACAAGTTATTTGCTCCGGAC
TTTTCGGAGCCGTCCTCCTACTCGCCGCCGACATGATCTCCCGCAACCTTCCCACCAGCTACGCCGTCCCAGTAGGACTG
ACCACCGGAGTGATCGGCGGCCTCTACCTGCTGTGGATCCTCACCCGACAAAAGGCTGTTTAA

Upstream 100 bases:

>100_bases
TCATTATCTTCCCTGCAGAAATTGGTGCTGGAATCATGACTGCTTTTATCGGCGCTCCGTTTTTCATCTGGCTTGTCAGA
CGAGGAAAGGTGTCCGGCTT

Downstream 100 bases:

>100_bases
CTGTGAATTCACCACTTCAAGCCATCGATTCCACCCTGGGATACAACGGATACACCGTCAGTGAACACCTGAATGTGGAT
ATCCCTGACCGATCCTTCAC

Product: hypothetical protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTMRVALGRVQVFVEKRTALLALALCLAAAALAVYSVASGTINYSLAEVASALALRGEDKTELVIWSIRLPRAVAAIAVG
MALGAAGSVFQSISRNALGSPDVIGFTTGAATGAVLQIVLYNKGATATALSAVAFGVVTAVIVYLLSRNRGSTGGYRLVL
IGIGVSAMLSALNTLLLAWGDLDLAVKARIWLSGSLNAREWNDVYPALIALAICLPMLIYYSRPLNILEMGDDQAKQLGV
NTERLRLIVMILGVLLTSVAVAAAGPIAFIALAAPQIVSRITGAARVQVICSGLFGAVLLLAADMISRNLPTSYAVPVGL
TTGVIGGLYLLWILTRQKAV

Sequences:

>Translated_340_residues
MTMRVALGRVQVFVEKRTALLALALCLAAAALAVYSVASGTINYSLAEVASALALRGEDKTELVIWSIRLPRAVAAIAVG
MALGAAGSVFQSISRNALGSPDVIGFTTGAATGAVLQIVLYNKGATATALSAVAFGVVTAVIVYLLSRNRGSTGGYRLVL
IGIGVSAMLSALNTLLLAWGDLDLAVKARIWLSGSLNAREWNDVYPALIALAICLPMLIYYSRPLNILEMGDDQAKQLGV
NTERLRLIVMILGVLLTSVAVAAAGPIAFIALAAPQIVSRITGAARVQVICSGLFGAVLLLAADMISRNLPTSYAVPVGL
TTGVIGGLYLLWILTRQKAV
>Mature_339_residues
TMRVALGRVQVFVEKRTALLALALCLAAAALAVYSVASGTINYSLAEVASALALRGEDKTELVIWSIRLPRAVAAIAVGM
ALGAAGSVFQSISRNALGSPDVIGFTTGAATGAVLQIVLYNKGATATALSAVAFGVVTAVIVYLLSRNRGSTGGYRLVLI
GIGVSAMLSALNTLLLAWGDLDLAVKARIWLSGSLNAREWNDVYPALIALAICLPMLIYYSRPLNILEMGDDQAKQLGVN
TERLRLIVMILGVLLTSVAVAAAGPIAFIALAAPQIVSRITGAARVQVICSGLFGAVLLLAADMISRNLPTSYAVPVGLT
TGVIGGLYLLWILTRQKAV

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=41.5902140672783, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1790740, Length=282, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786347, Length=280, Percent_Identity=31.7857142857143, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790741, Length=310, Percent_Identity=32.9032258064516, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=31.3380281690141, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786805, Length=224, Percent_Identity=32.5892857142857, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35349; Mature: 35217

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRVALGRVQVFVEKRTALLALALCLAAAALAVYSVASGTINYSLAEVASALALRGEDK
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
TELVIWSIRLPRAVAAIAVGMALGAAGSVFQSISRNALGSPDVIGFTTGAATGAVLQIVL
CEEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHEEEEE
YNKGATATALSAVAFGVVTAVIVYLLSRNRGSTGGYRLVLIGIGVSAMLSALNTLLLAWG
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCC
DLDLAVKARIWLSGSLNAREWNDVYPALIALAICLPMLIYYSRPLNILEMGDDQAKQLGV
CCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCC
NTERLRLIVMILGVLLTSVAVAAAGPIAFIALAAPQIVSRITGAARVQVICSGLFGAVLL
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LAADMISRNLPTSYAVPVGLTTGVIGGLYLLWILTRQKAV
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMRVALGRVQVFVEKRTALLALALCLAAAALAVYSVASGTINYSLAEVASALALRGEDK
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
TELVIWSIRLPRAVAAIAVGMALGAAGSVFQSISRNALGSPDVIGFTTGAATGAVLQIVL
CEEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHEEEEE
YNKGATATALSAVAFGVVTAVIVYLLSRNRGSTGGYRLVLIGIGVSAMLSALNTLLLAWG
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCC
DLDLAVKARIWLSGSLNAREWNDVYPALIALAICLPMLIYYSRPLNILEMGDDQAKQLGV
CCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCC
NTERLRLIVMILGVLLTSVAVAAAGPIAFIALAAPQIVSRITGAARVQVICSGLFGAVLL
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LAADMISRNLPTSYAVPVGLTTGVIGGLYLLWILTRQKAV
HHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]