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The map label for this gene is trmH [C]

Identifier: 145296765

GI number: 145296765

Start: 2954494

End: 2955114

Strand: Reverse

Name: trmH [C]

Synonym: cgR_2669

Alternate gene names: 145296765

Gene position: 2955114-2954494 (Counterclockwise)

Preceding gene: 145296766

Following gene: 145296764

Centisome position: 89.17

GC content: 56.68

Gene sequence:

>621_bases
GTGGGCAAAGGTCCATGGGAAGAGGAAAACCCCGGCGTACCTCGGCCTACAAACCCGCTTTTCGACGTCACCCTCCTCAA
CGAGGGCGATCGCCGCAACGTTGTTGACGCCTATCGTTATTGGACCCGTGAGGCGATTGTTGAAGATATCGACACCCGCC
GCCACAGCCTCCACGTAGCGATCGAAAACTTTGAAAACGACGCCAACATCGGCACCGTCGTGCGCACCGCCAACGCCTTT
GCCGTGAACACAGTCCACATTGTGGGCAGGCGTCGGTGGAACCGCAGGGGAGCCATGGTGACTGACCGTTACCAGCACCT
CATGCACCACGAAGACGTTGATTCGCTGCTTGCGTGGGCAATTGCAGAAGGGCTTACCATCGTCGCGATCGATAACACCC
CAGGTTCTGTGCCTTTGGAAACCGCTGAGTTGCCGAAGAACTGCCTGTTGCTGTTTGGTCAGGAAGGCCCAGGTGTCACC
GAAGCTGCGCGTGCAGGTGCGTTAATGACCTGTTCGATTGCCCAATTTGGTTCCACACGATCCATCAACGCGGGTGTAGC
TGCTGGTATTGCAATGCATGCATGGATTCGTCAACATGCCGACTTATCGCAAGCCTGGTAA

Upstream 100 bases:

>100_bases
GTTATCGCAGCGGAAGGTCTTCCTTACCGCAGCTTGCTGGGACTTTCTGACCTTGGACTCAACTAACACCCCCGGCCCCA
CGGAGTGGGGCGAGTCCCGC

Downstream 100 bases:

>100_bases
TTTTATACCCTAGATCGTTAGACTTTCGTTATACTTTTGGGTGTCGTATTTAGTTGTGCAACACGTGCATTGGAGCGAAG
AAACACTCAGTGTTAGACAA

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine; tRNATyr Containing 2'-O-methylguanosine [C]

Alternate protein names: RNA Methyltransferase; rRNA Methylase; TRNA/RRNA MethyltransferaU; RNA Methyltransferase TrmH Family; 23S RRNA Methyltransferase; TrmH Family RNA Methyltransferase; RNA Methylase Family Protein; Spou RRNA Methylase Family Protein; Methyltransferase; SpoU RRNA Methylase Family Protein; SPOU RRNA Methylase Family Protein; tRNA Guanosine-2-O-Methyltransferase

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MGKGPWEEENPGVPRPTNPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENFENDANIGTVVRTANAF
AVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAEGLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVT
EAARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW

Sequences:

>Translated_206_residues
MGKGPWEEENPGVPRPTNPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENFENDANIGTVVRTANAF
AVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAEGLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVT
EAARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW
>Mature_205_residues
GKGPWEEENPGVPRPTNPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVAIENFENDANIGTVVRTANAFA
VNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWAIAEGLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVTE
AARAGALMTCSIAQFGSTRSINAGVAAGIAMHAWIRQHADLSQAW

Specific function: Specifically Methylates Guanosine-18 In Various tRNAs. [C]

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.34 [C]

Molecular weight: Translated: 22759; Mature: 22628

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGPWEEENPGVPRPTNPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVA
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHEEEEE
IENFENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWA
EECCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
IAEGLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVTEAARAGALMTCSIAQFGSTR
HHCCCEEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHHCCEEEEEEHHHCCCCC
SINAGVAAGIAMHAWIRQHADLSQAW
CCCCHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
GKGPWEEENPGVPRPTNPLFDVTLLNEGDRRNVVDAYRYWTREAIVEDIDTRRHSLHVA
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHEEEEE
IENFENDANIGTVVRTANAFAVNTVHIVGRRRWNRRGAMVTDRYQHLMHHEDVDSLLAWA
EECCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
IAEGLTIVAIDNTPGSVPLETAELPKNCLLLFGQEGPGVTEAARAGALMTCSIAQFGSTR
HHCCCEEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHHCCEEEEEEHHHCCCCC
SINAGVAAGIAMHAWIRQHADLSQAW
CCCCHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; tRNATyr [C]

Specific reaction: S-Adenosyl-L-methionine + tRNATyr = S-adenosyl-L-homocysteine + tRNATyr Containing 2'-O-methylguanosine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA