Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 145295744

GI number: 145295744

Start: 1857231

End: 1857803

Strand: Reverse

Name: aroK [H]

Synonym: cgR_1671

Alternate gene names: 145295744

Gene position: 1857803-1857231 (Counterclockwise)

Preceding gene: 145295745

Following gene: 145295743

Centisome position: 56.06

GC content: 57.94

Gene sequence:

>573_bases
ATGGAGCGTAATGAAGTGAATGATCAAATTCACTTAGATCATCAATCAGATGACACCTCTGAATGCTCCTGCCCGATCGT
GGTTCTTGTGGGTTTGCCAGGAGCTGGAAAATCCACCATTGGACGTCGATTAGCGCGCGCCTTAAACACTGAACTCGTCG
ACTCCGACGAACTCATTGAGCGCGCCACCGGAAAAGCCTGCGGCGCCGTGTTCAGCGAGCTCGGCGAGCCAGCCTTCCGC
GAGCTCGAGGCCATCCACGTGGCCGAAGCACTGAAATCCTCCGGAGTGGTGAGCTTGGGAGGCGGATCTGTGCTGACAGA
ATCCACCCGTGAACTGCTCAAAGGCCACGACGTGGTCTGGATCGACGTGCCAGTAGAAGAAGGCATCAGGCGCACCGCAA
ACGAGCGTTCCCGCCCCGTGCTGCAAGCCGCCGACCCCGCCGAGCACTACCGCAACCTGGTGAAAGTGCGCACCCCGTTG
TACGAAGAGGTGGCAACCTACCGACTTCGCACCAACAACCGCAGCCCCCAGCAAGTGGTGGCAGCAGTGTTGCATCATCT
AGAAATCGATTAA

Upstream 100 bases:

>100_bases
CTGCAGAAATTCGGCGGTGACTCCCTGAGTGAAACCAAGAGCAACATTGACACCTACCTCAAAAACATTGAGGAACGAAT
GAAATTCGAAGGTTTAGAGG

Downstream 100 bases:

>100_bases
TTAAACCGGGCACCTGATTAACATTGGGCTGCCCGGTTTCTTCCTATTACAAGCGAAAGGCAACGTGCCCCATGAGCGCA
GCGCAGATTTTCAACACCGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MERNEVNDQIHLDHQSDDTSECSCPIVVLVGLPGAGKSTIGRRLARALNTELVDSDELIERATGKACGAVFSELGEPAFR
ELEAIHVAEALKSSGVVSLGGGSVLTESTRELLKGHDVVWIDVPVEEGIRRTANERSRPVLQAADPAEHYRNLVKVRTPL
YEEVATYRLRTNNRSPQQVVAAVLHHLEID

Sequences:

>Translated_190_residues
MERNEVNDQIHLDHQSDDTSECSCPIVVLVGLPGAGKSTIGRRLARALNTELVDSDELIERATGKACGAVFSELGEPAFR
ELEAIHVAEALKSSGVVSLGGGSVLTESTRELLKGHDVVWIDVPVEEGIRRTANERSRPVLQAADPAEHYRNLVKVRTPL
YEEVATYRLRTNNRSPQQVVAAVLHHLEID
>Mature_190_residues
MERNEVNDQIHLDHQSDDTSECSCPIVVLVGLPGAGKSTIGRRLARALNTELVDSDELIERATGKACGAVFSELGEPAFR
ELEAIHVAEALKSSGVVSLGGGSVLTESTRELLKGHDVVWIDVPVEEGIRRTANERSRPVLQAADPAEHYRNLVKVRTPL
YEEVATYRLRTNNRSPQQVVAAVLHHLEID

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=41.2121212121212, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786587, Length=161, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20822; Mature: 20822

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNEVNDQIHLDHQSDDTSECSCPIVVLVGLPGAGKSTIGRRLARALNTELVDSDELIE
CCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
RATGKACGAVFSELGEPAFRELEAIHVAEALKSSGVVSLGGGSVLTESTRELLKGHDVVW
HHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCEEE
IDVPVEEGIRRTANERSRPVLQAADPAEHYRNLVKVRTPLYEEVATYRLRTNNRSPQQVV
EECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AAVLHHLEID
HHHHHHHCCC
>Mature Secondary Structure
MERNEVNDQIHLDHQSDDTSECSCPIVVLVGLPGAGKSTIGRRLARALNTELVDSDELIE
CCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
RATGKACGAVFSELGEPAFRELEAIHVAEALKSSGVVSLGGGSVLTESTRELLKGHDVVW
HHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCEEE
IDVPVEEGIRRTANERSRPVLQAADPAEHYRNLVKVRTPLYEEVATYRLRTNNRSPQQVV
EECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AAVLHHLEID
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]