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The map label for this gene is aroB

Identifier: 145295743

GI number: 145295743

Start: 1856062

End: 1857159

Strand: Reverse

Name: aroB

Synonym: cgR_1670

Alternate gene names: 145295743

Gene position: 1857159-1856062 (Counterclockwise)

Preceding gene: 145295744

Following gene: 145295742

Centisome position: 56.04

GC content: 58.65

Gene sequence:

>1098_bases
ATGAGCGCAGCGCAGATTTTCAACACCGTCCACGTCAATGGATCTTCCCCCTATGATGTCCACATTGGTTCCGGCCTCAA
CGAGCTCATTGTTCAGCGCGCAGCGGAATCAGGCGCGGAGCAGGTAGCGATTTTGCACCAGCCCAGCATGGATGACATTG
CATCCGAGTTGGATGCAGCACTAGTCGCTGCTGGTTTGAAGGTCCTGCACCTTAATGTTCCCGATGCGGAAAACGGCAAG
TCCTTGGAAGTAGCGGGGCAGTGCTGGGATGAATTGGGTGGCGCAGCATTCGGCCGCCGCGATATCGTCATCGGACTTGG
TGGCGGTGCTGCCACAGATCTCGCGGGATTCGTCGCTGCTGCGTGGATGCGTGGCGTGCGCGTCATTCAGGTTCCAACCA
CCTTGTTGGCCATGGTGGACGCTGCGGTGGGCGGCAAGACTGGCATCAATACCGCCGCAGGCAAGAACCTTGTGGGCGCG
TTCCACGAGCCTGACGCAGTATTCATTGACACCGAACGCCTAGCCACCCTGCCTGACGCGGAAATCATCGCGGGATCCGC
CGAAATCATCAAAACTGGTTTCATCGCCGACCCAGAAATCCTGCGCCTTTACGAAACTGATCCCGCAGCCTGCCTGAAGA
AAGAAGTCGAAGGCTCCCACCTACCTGAACTGATTTGGCGCTCCGTCACCGTCAAGGGCTCCGTGGTCGGCCAAGACCTC
AAAGAATCTAGCCTGCGCGAAATCCTCAACTACGGACACACCTTTGCCCACGCCGTCGAACTCCGCGAAAACTTCCGCTG
GCGCCACGGCAATGCCGTTGCAGTGGGCATGATGTTCATCGCTAACCTCTCCCACAAGCTCGGGCTTATCGACGCGCCCC
TCCTCGAGCGCCACCGCTCAATCCTGGCGGCCATCGGTCTGCCCACTTCCTACGAAGGCGGAGCCTTCGACGAGCTTTAC
GACGGCATGACCCGCGACAAGAAAAACCGCGACGGCAACATCCGCTTCGTCGCACTGACCGCCGTGGGCGAGGTTACCCG
CATTGAGGGGCCCTCAAAACAAGATTTACAGAGTGCTTATGAGGCAATCAGCCACTAA

Upstream 100 bases:

>100_bases
CAGTGTTGCATCATCTAGAAATCGATTAATTAAACCGGGCACCTGATTAACATTGGGCTGCCCGGTTTCTTCCTATTACA
AGCGAAAGGCAACGTGCCCC

Downstream 100 bases:

>100_bases
GTGTTGAGTAATCTACTAGTTTGGACTAGAAGTTATCCACTTTCAGTGAATTTTTAAGGAGAGAACATGGCTTTGGCTGA
TACCCGATTTGCCACTCGTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSAAQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGK
SLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGA
FHEPDAVFIDTERLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELY
DGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH

Sequences:

>Translated_365_residues
MSAAQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGK
SLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGA
FHEPDAVFIDTERLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELY
DGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH
>Mature_364_residues
SAAQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAALVAAGLKVLHLNVPDAENGKS
LEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAAAWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAF
HEPDAVFIDTERLATLPDAEIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDLK
ESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRSILAAIGLPTSYEGGAFDELYD
GMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAYEAISH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=335, Percent_Identity=38.2089552238806, Blast_Score=187, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320332, Length=369, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_CORGB (A4QEJ6)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138564.1
- ProteinModelPortal:   A4QEJ6
- SMR:   A4QEJ6
- STRING:   A4QEJ6
- GeneID:   4992935
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1670
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   FAAYQEI
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38845; Mature: 38713

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAA
CCHHHEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
LVAAGLKVLHLNVPDAENGKSLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAA
HHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
AWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPDAVFIDTERLATLPDA
HHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEHHHHCCCCCH
EIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
HHCCCCHHHHHHCCCCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHEEECHHHCCHH
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ILAAIGLPTSYEGGAFDELYDGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAY
HHHHHCCCCCCCCCCHHHHHCCHHCCCCCCCCCEEEEEEEECCCHHCCCCCCHHHHHHHH
EAISH
HHHCC
>Mature Secondary Structure 
SAAQIFNTVHVNGSSPYDVHIGSGLNELIVQRAAESGAEQVAILHQPSMDDIASELDAA
CHHHEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
LVAAGLKVLHLNVPDAENGKSLEVAGQCWDELGGAAFGRRDIVIGLGGGAATDLAGFVAA
HHHCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
AWMRGVRVIQVPTTLLAMVDAAVGGKTGINTAAGKNLVGAFHEPDAVFIDTERLATLPDA
HHHCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEHHHHCCCCCH
EIIAGSAEIIKTGFIADPEILRLYETDPAACLKKEVEGSHLPELIWRSVTVKGSVVGQDL
HHCCCCHHHHHHCCCCCHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHEEECHHHCCHH
KESSLREILNYGHTFAHAVELRENFRWRHGNAVAVGMMFIANLSHKLGLIDAPLLERHRS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ILAAIGLPTSYEGGAFDELYDGMTRDKKNRDGNIRFVALTAVGEVTRIEGPSKQDLQSAY
HHHHHCCCCCCCCCCHHHHHCCHHCCCCCCCCCEEEEEEEECCCHHCCCCCCHHHHHHHH
EAISH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA