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The map label for this gene is aroC [H]

Identifier: 145295745

GI number: 145295745

Start: 1857793

End: 1859025

Strand: Reverse

Name: aroC [H]

Synonym: cgR_1672

Alternate gene names: 145295745

Gene position: 1859025-1857793 (Counterclockwise)

Preceding gene: 145295746

Following gene: 145295744

Centisome position: 56.09

GC content: 56.53

Gene sequence:

>1233_bases
ATGCTAGGCATGCTTCGATGGACTACAGCAGGTGAATCCCACGGCCAGGCGCTTATCGCCACGGTTGAACACATGCCAGC
AGGCGTGCCCGTGACTAAAGATGAGGTCTCGTATCAATTGGCGCGCCGACGCCTTGGATATGGTCGCGGCGCTCGCATGA
AGTTTGAGCAAGACGCGTTGACCTTCCTGACCGGCATCCGCCACGGCCTCACTTTGGGTAGCCCCATCTCAATCATGATC
GGCAACACTGAGTGGGATAAGTGGACCACCATCATGTCCTCTGACGCTTTGGACATGGAAGACCCAGACAACGTTGCGGC
GATGTCTTCGGGTCGCGGTGCAAAACTGACTCGTCCGCGTCCAGGCCACGCAGATTACGCAGGCATGCTCAAGTACGGAT
TCGATGATGCCCGCAACGTGCTGGAGCGTTCTTCAGCCCGTGAGACGGCAGCTCGCGTGGCAGCAGCAACCGTTGCGCGT
TCCTTCCTCCGTGAAACCTTGGGCGTGGAGGTGCTCTCTCACGTAATTTCCATTGGTGCGTCCGAGCCTTACGTCGGCGC
GGAGCCAACCTTTGCAGATATTCAAGCAATCGATGATTCCCCAGTTCGTGCATTCGGTAAAGACGCTGAAAAATCCATGA
TCGCGGAAATCGAGGCCGCAAAGAAAGCCGGCGATACCCTCGGTGGCATCGTGGAAGTGATTGTTGAAGGCCTACCCATC
GGTTTGGGCTCACACATTTCTGGCGAAGATCGCCTCGATGCGCAGATCGCAGCTGCACTCATGGGCATTCAGGCCATCAA
GGGCGTGGAAATCGGTGACGGTTTCGAAGAAGCTCGTCGACGTGGCTCCGAAGCCCACGATGAAGTGTTCCTGGATGACA
ACGGCGTATACCGCAACACCAACCGTGCAGGTGGCCTCGAAGGCGGCATGACCAACGGTGAAACCCTGCGCGTTCGTGCT
GGCATGAAGCCAATTTCTACTGTGCCTCGCGCCCTGAAAACCATTGATATGGAAAACGGCAAGGCAGCAACCGGAATCCA
CCAGCGTTCCGACGTGTGCGCTGTTCCAGCCGCCGGTGTCGTTGCAGAAGCAATGGTCACCCTGGTTCTCGCCCGCGCAG
TCCTGCAGAAATTCGGCGGTGACTCCCTGAGTGAAACCAAGAGCAACATTGACACCTACCTCAAAAACATTGAGGAACGA
ATGAAATTCGAAGGTTTAGAGGATGGAGCGTAA

Upstream 100 bases:

>100_bases
CGCTAGTGCCTGCAGTTATGTCGCTTTTTGACGTCGAAAAGCAATTTTAAAAAGCCCTTGGGGTGGGCTGGATACGTCTT
CTGCGGCCTTTCGTGCGATA

Downstream 100 bases:

>100_bases
TGAAGTGAATGATCAAATTCACTTAGATCATCAATCAGATGACACCTCTGAATGCTCCTGCCCGATCGTGGTTCTTGTGG
GTTTGCCAGGAGCTGGAAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA

Sequences:

>Translated_410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA
>Mature_410_residues
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMI
GNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVAR
SFLRETLGVEVLSHVISIGASEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPI
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRA
GMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEER
MKFEGLEDGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=374, Percent_Identity=34.4919786096257, Blast_Score=175, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6321290, Length=382, Percent_Identity=31.9371727748691, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 43731; Mature: 43731

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDAL
CCCCEEECCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHH
TFLTGIRHGLTLGSPISIMIGNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPR
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
PGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVARSFLRETLGVEVLSHVISIGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPI
CCCCCCCCCCHHHHEECCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEECC
NRAGGLEGGMTNGETLRVRAGMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGV
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
VAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEERMKFEGLEDGA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLGMLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDAL
CCCCEEECCCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHH
TFLTGIRHGLTLGSPISIMIGNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPR
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
PGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVARSFLRETLGVEVLSHVISIGA
CCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPI
CCCCCCCCCCHHHHEECCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEECCCCCEECC
NRAGGLEGGMTNGETLRVRAGMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGV
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHH
VAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEERMKFEGLEDGA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]