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The map label for this gene is betP [H]

Identifier: 145295062

GI number: 145295062

Start: 1109545

End: 1111332

Strand: Direct

Name: betP [H]

Synonym: cgR_1005

Alternate gene names: 145295062

Gene position: 1109545-1111332 (Clockwise)

Preceding gene: 145295061

Following gene: 145295063

Centisome position: 33.48

GC content: 51.06

Gene sequence:

>1788_bases
ATGACTACATCTGACCCAAATTCGAAACCGATAGTGGAAGATGCTCAGCCAGAGCAGATTACCGCAACCGAAGAACTGGC
GGGTTTGCTTGAGAATACAACTAACCTGGAAGGGAAACTGGCCGACGCCGAAGAGGAAATTATCCTCGAAGGCGAAGACG
CCCAGGCCTCACTTAACTGGTCAGTCATCGTTCCAGCCCTAGTCATTGTCCTAGCGACAGTGGTGTGGGGTATCGGATTC
AAAGATAGCTTTACCAACTTTGCTAGTTCTGCGTTGTCAGCAGTAGTTGACAATCTCGGCTGGGCCTTCATTTTGTTTGG
CACAGTCTTTGTATTTTTTATCGTTGTTATCGCTGCTAGTAAATTCGGCACGATTCGCTTAGGCCGCATTGATGAAGCAC
CAGAGTTTCGCACGGTGTCATGGATTTCCATGATGTTTGCTGCAGGTATGGGTATTGGTTTGATGTTCTACGGAACCACA
GAACCTTTAACCTTCTACCGCAATGGTGTACCTGGATATGATGAACACAATGTTGGCGTTGCTATGTCCACGACAATGTT
CCACTGGACCTTGCATCCATGGGCTATCTACGCAATTGTGGGCCTAGCCATTGCCTATTCGACCTTCCGAGTGGGCCGTA
AACAGCTTCTAAGCTCTGCATTCGTGCCACTCATTGGTGAAAAAGGTGCAGAAGGATGGTTGGGCAAGCTCATCGACATC
CTGGCGATTATCGCCACAGTATTCGGCACCGCATGTTCCCTTGGCCTGGGTGCGCTGCAGATCGGTGCAGGACTTTCCGC
AGCCAACATCATTGAAAATCCGAGTGACTGGACTGTCATTGGTATTGTTTCTGTCTTGACCTTGGCATTTATCTTCTCTG
CTATTTCTGGTGTGGGCAAGGGAATCCAGTACCTCTCCAACGCCAACATGGTTCTGGCAGCTTTGCTCGCGATTTTCGTG
TTCGTTGTCGGACCAACCGTGTCGATTTTGAACCTGCTGCCAGGTTCTATTGGCAACTACCTGTCCAACTTCTTCCAAAT
GGCAGGCCGCACTGCCATGAGTGCCGACGGCACAGCAGGTGAGTGGCTAGGTAGCTGGACCATCTTCTACTGGGCATGGT
GGATCTCTTGGTCACCATTCGTAGGAATGTTCTTGGCACGTATTTCCCGTGGCCGCTCCATCCGTGAGTTCATCCTGGGC
GTGTTGCTCGTCCCAGCAGGTGTGTCCACCGTATGGTTCTCCATTTTTGGTGGCACTGCGATTGTCTTCGAACAAAATGG
GGAATCCATTTGGGGTGATGGTGCAGCAGAAGAGCAGCTCTTTGGATTGCTTCATGCACTTCCAGGTGGGCAAATCATGG
GCATCATCGCCATGATTTTGCTGGGTACTTTCTTCATTACCTCTGCTGACTCTGCTTCCACCGTCATGGGCACCATGAGT
CAGAACGGCCAGCTGGAAGCCAACAAGTGGGTGACAGCTGCCTGGGGTGTTGCTACCGCAGCTATTGGACTAACGCTATT
GCTTTCTGGTGGTGACAATGCCTTGAACAACTTGCAAAACGTCACCATCGTGGCTGCAACACCATTCCTGTTTGTGGTTA
TTGGATTGATGTTTGCGTTAGTCAAGGACTTAAGCAATGATGTGATCTACCTCGAGTACCGTGAGCAGCAACGCTTCAAC
GCGCGCCTTGCCCGTGAACGTCGTGTTCACAATGAACACCGCAAGCGTGAACTGGCTGCAAAGCGACGCAGGGAGCGTAA
GGCGAGTGGTGCGGGGAAGCGTCGATAG

Upstream 100 bases:

>100_bases
TAACAGCTATGTAAAAGACCAGGTCAGGTTCGGGTCGGTTTAGGTACGAAACCCATTTTTCGGTTTGCTTTCCAGGTTTC
CCCAAGTAAAGGTGAGTTTT

Downstream 100 bases:

>100_bases
GCAATTTTAACCCCTGATACCCCTTTCCGGCCGGGCATAAATTAAGGTGGTACGCATGACGAAGAACGTGCTCGTATCTG
TTGCCTGGCCGTATGCCAAC

Product: hypothetical protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTTSDPNSKPIVEDAQPEQITATEELAGLLENTTNLEGKLADAEEEIILEGEDAQASLNWSVIVPALVIVLATVVWGIGF
KDSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAASKFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTT
EPLTFYRNGVPGYDEHNVGVAMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDI
LAIIATVFGTACSLGLGALQIGAGLSAANIIENPSDWTVIGIVSVLTLAFIFSAISGVGKGIQYLSNANMVLAALLAIFV
FVVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILG
VLLVPAGVSTVWFSIFGGTAIVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMS
QNGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALNNLQNVTIVAATPFLFVVIGLMFALVKDLSNDVIYLEYREQQRFN
ARLARERRVHNEHRKRELAAKRRRERKASGAGKRR

Sequences:

>Translated_595_residues
MTTSDPNSKPIVEDAQPEQITATEELAGLLENTTNLEGKLADAEEEIILEGEDAQASLNWSVIVPALVIVLATVVWGIGF
KDSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAASKFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTT
EPLTFYRNGVPGYDEHNVGVAMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDI
LAIIATVFGTACSLGLGALQIGAGLSAANIIENPSDWTVIGIVSVLTLAFIFSAISGVGKGIQYLSNANMVLAALLAIFV
FVVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILG
VLLVPAGVSTVWFSIFGGTAIVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMS
QNGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALNNLQNVTIVAATPFLFVVIGLMFALVKDLSNDVIYLEYREQQRFN
ARLARERRVHNEHRKRELAAKRRRERKASGAGKRR
>Mature_594_residues
TTSDPNSKPIVEDAQPEQITATEELAGLLENTTNLEGKLADAEEEIILEGEDAQASLNWSVIVPALVIVLATVVWGIGFK
DSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAASKFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTTE
PLTFYRNGVPGYDEHNVGVAMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDIL
AIIATVFGTACSLGLGALQIGAGLSAANIIENPSDWTVIGIVSVLTLAFIFSAISGVGKGIQYLSNANMVLAALLAIFVF
VVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAGEWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILGV
LLVPAGVSTVWFSIFGGTAIVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMSQ
NGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALNNLQNVTIVAATPFLFVVIGLMFALVKDLSNDVIYLEYREQQRFNA
RLARERRVHNEHRKRELAAKRRRERKASGAGKRR

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=528, Percent_Identity=34.469696969697, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788102, Length=472, Percent_Identity=29.6610169491525, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1786224, Length=514, Percent_Identity=28.4046692607004, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 64203; Mature: 64072

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSDPNSKPIVEDAQPEQITATEELAGLLENTTNLEGKLADAEEEIILEGEDAQASLNW
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCH
SVIVPALVIVLATVVWGIGFKDSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
KFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTTEPLTFYRNGVPGYDEHNVGV
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCCCE
AMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDI
EEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
LAIIATVFGTACSLGLGALQIGAGLSAANIIENPSDWTVIGIVSVLTLAFIFSAISGVGK
HHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GIQYLSNANMVLAALLAIFVFVVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAG
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
EWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILGVLLVPAGVSTVWFSIFGGTA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEE
IVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMS
EEEECCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
QNGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALNNLQNVTIVAATPFLFVVIGLMFAL
CCCCEECCCEEEHHHHHHHHHHHHHEEECCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHH
VKDLSNDVIYLEYREQQRFNARLARERRVHNEHRKRELAAKRRRERKASGAGKRR
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTSDPNSKPIVEDAQPEQITATEELAGLLENTTNLEGKLADAEEEIILEGEDAQASLNW
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCCCCCCCH
SVIVPALVIVLATVVWGIGFKDSFTNFASSALSAVVDNLGWAFILFGTVFVFFIVVIAAS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
KFGTIRLGRIDEAPEFRTVSWISMMFAAGMGIGLMFYGTTEPLTFYRNGVPGYDEHNVGV
CCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCCCE
AMSTTMFHWTLHPWAIYAIVGLAIAYSTFRVGRKQLLSSAFVPLIGEKGAEGWLGKLIDI
EEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHH
LAIIATVFGTACSLGLGALQIGAGLSAANIIENPSDWTVIGIVSVLTLAFIFSAISGVGK
HHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GIQYLSNANMVLAALLAIFVFVVGPTVSILNLLPGSIGNYLSNFFQMAGRTAMSADGTAG
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
EWLGSWTIFYWAWWISWSPFVGMFLARISRGRSIREFILGVLLVPAGVSTVWFSIFGGTA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEE
IVFEQNGESIWGDGAAEEQLFGLLHALPGGQIMGIIAMILLGTFFITSADSASTVMGTMS
EEEECCCCEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
QNGQLEANKWVTAAWGVATAAIGLTLLLSGGDNALNNLQNVTIVAATPFLFVVIGLMFAL
CCCCEECCCEEEHHHHHHHHHHHHHEEECCCCHHHHCCCCEEEEEHHHHHHHHHHHHHHH
VKDLSNDVIYLEYREQQRFNARLARERRVHNEHRKRELAAKRRRERKASGAGKRR
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]