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The map label for this gene is panE [C]

Identifier: 138896342

GI number: 138896342

Start: 2815431

End: 2816462

Strand: Reverse

Name: panE [C]

Synonym: GTNG_2705

Alternate gene names: 138896342

Gene position: 2816462-2815431 (Counterclockwise)

Preceding gene: 138896343

Following gene: 138896340

Centisome position: 79.33

GC content: 35.66

Gene sequence:

>1032_bases
ATGAGAATAGCAATTGTAGGGGCAGGTTCACTTGGTACGATTATTGGTGCCCTTTTAACTGAAGGCGGACAAAATGTTGA
TTTGATTGATGCGAATGAAGAAAATGTAAAAGCGTTGAATGAAAACGGTGCACAAATAACAGGATTTATTAAAAAACATG
TAAAAGTAAACGCCTTAACACCAGAACAGTTGGAAGATAAATATGATATTGTATTCCTTTTAACAAAACAAATGTATAAT
CATGTGGCATTAAATCAATTACTTCCACACTTACATACAGATAGTGTAGTCTGTACACTTCAAAATGGTGTTCCAGAAGA
CAATGTTGCTAATATTGTCGGAAAACATAGAACAATTGGCGGGGCTGTTGGATTTGGAGCTACTTGGCTAAGACCGGGAG
TTTCAGAATTAACAACTGAATGGGATATCGTTCAAAAGTTTGCGTTTGATATAGGTGAACTAGACGGAAAGATTACACCT
AGGGCTCAAAAAATTGCAGAAATTTTAAGTTTGGTTGGTCATTGTAAAGTGTCTGATAATATTTTGGGAATTAAGTGGGC
AAAACTTTTGATGAATGCGACGTTTAGTGGGATGTCTGCAGCTTTAGGATGTACATTTGGTGAGGTTTTATTCAATGAAA
GAGCAATGTATAGTCTTGCTCATATCGCTGATGAAACCATTAAGGTTGCCCGAGCGTTAGGAGTCAAAATGGTGCCCATG
CAAGGTAAAGATTTTGAATTTCTTGAATTAAAGGATGAAAAAGATATTCCGAATAAGATGGATTTTTACAAAGAAGTTTG
GACCCCACATGCAAAATTAAAAGCAAGTATGCTGCAAGATCTGGAAAAAGGAAAAAAAACAGAGATTGACTACATTAATG
GACATGTAAGTGCAAAAGGTCGGCTTGTTGGAATGAAAACCCCTTATAACGATCTAGTTGTGGAATTAGTAAAAAAGGCC
GAAGAACAAAAAATCGTTCCAGATTTCTCTGTCAATATCGAAAGATTTGATTCATTAAAGGTTAAAAGGTAA

Upstream 100 bases:

>100_bases
TTTAAAAGCTAAATTATTAAACGGAGTACTACTGTATGAATGGTTTGGCAATTAAAAGATCAATAATACAATGTCTATTT
AATTACGAGGAGGAGATATA

Downstream 100 bases:

>100_bases
TAAATAGAAATTAAATTGTGGATGATTGTAATAACATGGTATAGTTATTGAGTTGTGAAAAAGAATCCGATTATCAAATC
AGAATCCTTTTTCATAATAA

Product: 2-dehydropantoate 2-reductase-like protein

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRIAIVGAGSLGTIIGALLTEGGQNVDLIDANEENVKALNENGAQITGFIKKHVKVNALTPEQLEDKYDIVFLLTKQMYN
HVALNQLLPHLHTDSVVCTLQNGVPEDNVANIVGKHRTIGGAVGFGATWLRPGVSELTTEWDIVQKFAFDIGELDGKITP
RAQKIAEILSLVGHCKVSDNILGIKWAKLLMNATFSGMSAALGCTFGEVLFNERAMYSLAHIADETIKVARALGVKMVPM
QGKDFEFLELKDEKDIPNKMDFYKEVWTPHAKLKASMLQDLEKGKKTEIDYINGHVSAKGRLVGMKTPYNDLVVELVKKA
EEQKIVPDFSVNIERFDSLKVKR

Sequences:

>Translated_343_residues
MRIAIVGAGSLGTIIGALLTEGGQNVDLIDANEENVKALNENGAQITGFIKKHVKVNALTPEQLEDKYDIVFLLTKQMYN
HVALNQLLPHLHTDSVVCTLQNGVPEDNVANIVGKHRTIGGAVGFGATWLRPGVSELTTEWDIVQKFAFDIGELDGKITP
RAQKIAEILSLVGHCKVSDNILGIKWAKLLMNATFSGMSAALGCTFGEVLFNERAMYSLAHIADETIKVARALGVKMVPM
QGKDFEFLELKDEKDIPNKMDFYKEVWTPHAKLKASMLQDLEKGKKTEIDYINGHVSAKGRLVGMKTPYNDLVVELVKKA
EEQKIVPDFSVNIERFDSLKVKR
>Mature_343_residues
MRIAIVGAGSLGTIIGALLTEGGQNVDLIDANEENVKALNENGAQITGFIKKHVKVNALTPEQLEDKYDIVFLLTKQMYN
HVALNQLLPHLHTDSVVCTLQNGVPEDNVANIVGKHRTIGGAVGFGATWLRPGVSELTTEWDIVQKFAFDIGELDGKITP
RAQKIAEILSLVGHCKVSDNILGIKWAKLLMNATFSGMSAALGCTFGEVLFNERAMYSLAHIADETIKVARALGVKMVPM
QGKDFEFLELKDEKDIPNKMDFYKEVWTPHAKLKASMLQDLEKGKKTEIDYINGHVSAKGRLVGMKTPYNDLVVELVKKA
EEQKIVPDFSVNIERFDSLKVKR

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 37885; Mature: 37885

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAIVGAGSLGTIIGALLTEGGQNVDLIDANEENVKALNENGAQITGFIKKHVKVNALT
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEHHHCEEEECCC
PEQLEDKYDIVFLLTKQMYNHVALNQLLPHLHTDSVVCTLQNGVPEDNVANIVGKHRTIG
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCCCC
GAVGFGATWLRPGVSELTTEWDIVQKFAFDIGELDGKITPRAQKIAEILSLVGHCKVSDN
CHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
ILGIKWAKLLMNATFSGMSAALGCTFGEVLFNERAMYSLAHIADETIKVARALGVKMVPM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
QGKDFEFLELKDEKDIPNKMDFYKEVWTPHAKLKASMLQDLEKGKKTEIDYINGHVSAKG
CCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCE
RLVGMKTPYNDLVVELVKKAEEQKIVPDFSVNIERFDSLKVKR
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MRIAIVGAGSLGTIIGALLTEGGQNVDLIDANEENVKALNENGAQITGFIKKHVKVNALT
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCEEEEEHHHCEEEECCC
PEQLEDKYDIVFLLTKQMYNHVALNQLLPHLHTDSVVCTLQNGVPEDNVANIVGKHRTIG
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCCCC
GAVGFGATWLRPGVSELTTEWDIVQKFAFDIGELDGKITPRAQKIAEILSLVGHCKVSDN
CHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
ILGIKWAKLLMNATFSGMSAALGCTFGEVLFNERAMYSLAHIADETIKVARALGVKMVPM
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
QGKDFEFLELKDEKDIPNKMDFYKEVWTPHAKLKASMLQDLEKGKKTEIDYINGHVSAKG
CCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCE
RLVGMKTPYNDLVVELVKKAEEQKIVPDFSVNIERFDSLKVKR
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]