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The map label for this gene is ezrA

Identifier: 138896337

GI number: 138896337

Start: 2808897

End: 2810600

Strand: Reverse

Name: ezrA

Synonym: GTNG_2700

Alternate gene names: 138896337

Gene position: 2810600-2808897 (Counterclockwise)

Preceding gene: 138896340

Following gene: 138896336

Centisome position: 79.16

GC content: 53.11

Gene sequence:

>1704_bases
ATGGAAATCGTATGGATCGTTCTGCTCCTCGGCGCAGGAGTAATCATATACAATCATATGTATCGGAAGAAGATGTACCG
GGAAATCGACCGGCTTGAGGCATGGAAAATCGAACTGATGAACCGGCCGGTGCCGGATGAGTTAGCGAAAGTGAAACAGC
TGAACATGACCGGGGAAACGGAGCAGCTGTTTGAACGGTGGCGCCAACAATGGGATGAGATCGTAGCCGTGAAGCTGCCG
AATGTCGAAGAACAGCTGTTTGATACCGAGACGTTTCTGGACAAATACCGGTACCGGCAGGCACGCAAGTTGATTGGGCA
AATTGAGGATGGGTTGCGTCGCCTTGAGGAAGAGGTGCATCAAATCATTGATGAAGTTAACGAGCTGATCGGAAGCGAAG
AGCAAAGCCGGACGGAAATCGAAGAGCTGCGCGCTGTCCATCGGGAGGCGAAGAAAACGCTGCTTGCTTATCGGTATACG
TTTGGGGCGGCTGCCGATTTGCTTGACGTCCGCCTAACCGAGGCCGAAAAGCAGTTTGAGTCGTTTGCCAAATTGACGGA
AGCCGGCAACTATTTGGCAGCGCGCGGTGTCGTCCAGGAGCTGAAGCAGGAGCTTGACAGCCTGGCGACGATGATGGAAG
AGATTCCGGCGCTGCTTAGCGAGTGCCAAACCTCTCTTCCCGCCCAGTTGGCCGAGCTTGCTGACGGCTATCGGGAAATG
GAGCAAAGCGGGTACATACTCGACCATTTGCACATCGAACGCACATTGGCAGAAAAACAGGAGAAAATCGGACAATGCTT
AGCGATGATTGGCGAGCTGCGCATCGAAGAAGCGAAGCAAACCGTCGCTGAGCTGAAAGAAGAAATTGATACGCTATACG
ACTTGCTGGAAAAAGAAGTGCTCGCTAATCAATACGTGCAAACGGAAATGCCGCGCATTGGCGGCATGCTTACGGAGTTG
GCTGCCGAGGCAAAAGAAACGAGCGCTGAAGCGATGTTTGTTCAACAAAGCTACCATCTGCCGCCAAGCGACCTTGAAAA
ATATCGAAGCATTGAAAAACAGATGCATCAGCTGCAGAAGCGGTTTTTGCTGATCGAAGACCGCGTCGCTGAGGCGAAAA
CTGCCTATTCTTTGCTCAGAGAGGAGCTGGAACAGCTCGTCGGGCAAATTGACATGATGAAAGAAGAGCATGAACAGTTT
CGGTTGATGCTGCAGGCGCTGCGCAAAGACGAATTAATTGCCCGTGAAAAGCTCGACGACATGAGAAAAAAATTGTCCGA
ATCGCTTCGCCTCGTGCAAAAAAGCCGACTGCCGGGGCTGCCTGAGCCGTATGCGCTTGAGCTGACGGAAGCGAAAAACA
GCTTGCAAAATGTGGCCGCCCGCCTCGAAGAAAAGCCGCTCGACATGCCGGCGGTCGACCGGGCGCTCGAAGAAGCGAAA
GTTTCGGTTGAACGTCTTTATGAGCGAACAGTCGAAATGATTGAACAGGCGTCCTTGGCTGAACGGGCGATTCAATATGG
CAACCGCTACCGCCGCCGTTATCCGGCGGTTCACAAAGGGCTTGAGGAGGCCGAGTTTTTGTTCCGTCATTACGATTACG
AAGAGGCGCTCCGGCAGGCGGTGGCCACGATTGAAAGTGTCGAGCCAGGCGCGTTTGACCGCGTGCAGAAGCTTTGGCAG
GCGGACAACGAGGACGAACAATGA

Upstream 100 bases:

>100_bases
TTAACATGGTATCATAAAAACATTGAAAAACATATATTTTTGCCTTCTCCGCCGTATTCATTCATTTCGGAGTAGCTTGA
GTGCAAGGGGGCATTCGTGC

Downstream 100 bases:

>100_bases
TCAAAACCCGATAATTATCGGTGAAAACCGATATTTATCGGGTTTTTGGTGAATACTGTAAGTACGTGTGTGTTTTCAGC
TCGGTTTTATGTTATTATAC

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MEIVWIVLLLGAGVIIYNHMYRKKMYREIDRLEAWKIELMNRPVPDELAKVKQLNMTGETEQLFERWRQQWDEIVAVKLP
NVEEQLFDTETFLDKYRYRQARKLIGQIEDGLRRLEEEVHQIIDEVNELIGSEEQSRTEIEELRAVHREAKKTLLAYRYT
FGAAADLLDVRLTEAEKQFESFAKLTEAGNYLAARGVVQELKQELDSLATMMEEIPALLSECQTSLPAQLAELADGYREM
EQSGYILDHLHIERTLAEKQEKIGQCLAMIGELRIEEAKQTVAELKEEIDTLYDLLEKEVLANQYVQTEMPRIGGMLTEL
AAEAKETSAEAMFVQQSYHLPPSDLEKYRSIEKQMHQLQKRFLLIEDRVAEAKTAYSLLREELEQLVGQIDMMKEEHEQF
RLMLQALRKDELIAREKLDDMRKKLSESLRLVQKSRLPGLPEPYALELTEAKNSLQNVAARLEEKPLDMPAVDRALEEAK
VSVERLYERTVEMIEQASLAERAIQYGNRYRRRYPAVHKGLEEAEFLFRHYDYEEALRQAVATIESVEPGAFDRVQKLWQ
ADNEDEQ

Sequences:

>Translated_567_residues
MEIVWIVLLLGAGVIIYNHMYRKKMYREIDRLEAWKIELMNRPVPDELAKVKQLNMTGETEQLFERWRQQWDEIVAVKLP
NVEEQLFDTETFLDKYRYRQARKLIGQIEDGLRRLEEEVHQIIDEVNELIGSEEQSRTEIEELRAVHREAKKTLLAYRYT
FGAAADLLDVRLTEAEKQFESFAKLTEAGNYLAARGVVQELKQELDSLATMMEEIPALLSECQTSLPAQLAELADGYREM
EQSGYILDHLHIERTLAEKQEKIGQCLAMIGELRIEEAKQTVAELKEEIDTLYDLLEKEVLANQYVQTEMPRIGGMLTEL
AAEAKETSAEAMFVQQSYHLPPSDLEKYRSIEKQMHQLQKRFLLIEDRVAEAKTAYSLLREELEQLVGQIDMMKEEHEQF
RLMLQALRKDELIAREKLDDMRKKLSESLRLVQKSRLPGLPEPYALELTEAKNSLQNVAARLEEKPLDMPAVDRALEEAK
VSVERLYERTVEMIEQASLAERAIQYGNRYRRRYPAVHKGLEEAEFLFRHYDYEEALRQAVATIESVEPGAFDRVQKLWQ
ADNEDEQ
>Mature_567_residues
MEIVWIVLLLGAGVIIYNHMYRKKMYREIDRLEAWKIELMNRPVPDELAKVKQLNMTGETEQLFERWRQQWDEIVAVKLP
NVEEQLFDTETFLDKYRYRQARKLIGQIEDGLRRLEEEVHQIIDEVNELIGSEEQSRTEIEELRAVHREAKKTLLAYRYT
FGAAADLLDVRLTEAEKQFESFAKLTEAGNYLAARGVVQELKQELDSLATMMEEIPALLSECQTSLPAQLAELADGYREM
EQSGYILDHLHIERTLAEKQEKIGQCLAMIGELRIEEAKQTVAELKEEIDTLYDLLEKEVLANQYVQTEMPRIGGMLTEL
AAEAKETSAEAMFVQQSYHLPPSDLEKYRSIEKQMHQLQKRFLLIEDRVAEAKTAYSLLREELEQLVGQIDMMKEEHEQF
RLMLQALRKDELIAREKLDDMRKKLSESLRLVQKSRLPGLPEPYALELTEAKNSLQNVAARLEEKPLDMPAVDRALEEAK
VSVERLYERTVEMIEQASLAERAIQYGNRYRRRYPAVHKGLEEAEFLFRHYDYEEALRQAVATIESVEPGAFDRVQKLWQ
ADNEDEQ

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EZRA_GEOTN (A4IRU1)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126790.1
- STRING:   A4IRU1
- GeneID:   4967626
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_2700
- NMPDR:   fig|420246.5.peg.2603
- eggNOG:   COG4477
- HOGENOM:   HBG345654
- OMA:   MDIQELH
- ProtClustDB:   PRK04778
- BioCyc:   GTHE420246:GTNG_2700-MONOMER
- HAMAP:   MF_00728
- InterPro:   IPR010379

Pfam domain/function: PF06160 EzrA

EC number: NA

Molecular weight: Translated: 66201; Mature: 66201

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x106b7c48)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVWIVLLLGAGVIIYNHMYRKKMYREIDRLEAWKIELMNRPVPDELAKVKQLNMTGET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCH
EQLFERWRQQWDEIVAVKLPNVEEQLFDTETFLDKYRYRQARKLIGQIEDGLRRLEEEVH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIIDEVNELIGSEEQSRTEIEELRAVHREAKKTLLAYRYTFGAAADLLDVRLTEAEKQFE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAKLTEAGNYLAARGVVQELKQELDSLATMMEEIPALLSECQTSLPAQLAELADGYREM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSGYILDHLHIERTLAEKQEKIGQCLAMIGELRIEEAKQTVAELKEEIDTLYDLLEKEV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQYVQTEMPRIGGMLTELAAEAKETSAEAMFVQQSYHLPPSDLEKYRSIEKQMHQLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RFLLIEDRVAEAKTAYSLLREELEQLVGQIDMMKEEHEQFRLMLQALRKDELIAREKLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRKKLSESLRLVQKSRLPGLPEPYALELTEAKNSLQNVAARLEEKPLDMPAVDRALEEAK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSVERLYERTVEMIEQASLAERAIQYGNRYRRRYPAVHKGLEEAEFLFRHYDYEEALRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHCCHHHHHHHH
VATIESVEPGAFDRVQKLWQADNEDEQ
HHHHHHCCCCHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MEIVWIVLLLGAGVIIYNHMYRKKMYREIDRLEAWKIELMNRPVPDELAKVKQLNMTGET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCH
EQLFERWRQQWDEIVAVKLPNVEEQLFDTETFLDKYRYRQARKLIGQIEDGLRRLEEEVH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIIDEVNELIGSEEQSRTEIEELRAVHREAKKTLLAYRYTFGAAADLLDVRLTEAEKQFE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAKLTEAGNYLAARGVVQELKQELDSLATMMEEIPALLSECQTSLPAQLAELADGYREM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSGYILDHLHIERTLAEKQEKIGQCLAMIGELRIEEAKQTVAELKEEIDTLYDLLEKEV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANQYVQTEMPRIGGMLTELAAEAKETSAEAMFVQQSYHLPPSDLEKYRSIEKQMHQLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RFLLIEDRVAEAKTAYSLLREELEQLVGQIDMMKEEHEQFRLMLQALRKDELIAREKLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRKKLSESLRLVQKSRLPGLPEPYALELTEAKNSLQNVAARLEEKPLDMPAVDRALEEAK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSVERLYERTVEMIEQASLAERAIQYGNRYRRRYPAVHKGLEEAEFLFRHYDYEEALRQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHCCHHHHHHHH
VATIESVEPGAFDRVQKLWQADNEDEQ
HHHHHHCCCCHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA