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The map label for this gene is coaE [H]

Identifier: 138896289

GI number: 138896289

Start: 2758784

End: 2759389

Strand: Reverse

Name: coaE [H]

Synonym: GTNG_2652

Alternate gene names: 138896289

Gene position: 2759389-2758784 (Counterclockwise)

Preceding gene: 138896290

Following gene: 138896288

Centisome position: 77.72

GC content: 52.81

Gene sequence:

>606_bases
ATGGCAGTAACCATCGGGTTGACTGGGGGAATCGCGAGCGGGAAAAGTACGGTCAGTGCCATGATGCGCGAACTCGGCCT
TCCGGTCATTGACGCGGATGAGGCGGCGCGAGCTGTCGTTGAACCAGGAGAAGAGGCGTATCGGCAAATCGTTGCTACCT
TCGGTCCAGACATTTTGCAGATGAACGGCGAGATCGACCGGGCAAAACTCGGAGCGATCGTCTTTAACAACGAACAAGAG
CGGAAAAAGCTGAACGCCATCGTCCATCCGGCTGTGCGCCGGAAAATGCTTGCGGAAAAAGAGGAGCTCATTCGTTCCGG
AGCAAAAACGGTCGTCTTGGATATTCCTCTCTTATTTGAAAGCGGACTGACCGATTGGGTTGATAAAGTGCTCGTCGTTT
ACGTTGATGATGACGTTCAGCTTTGTCGCCTCATGGCGCGAAACGGCTTCACCGAGGAGGAAGCGATCGCCCGCATCCGC
GCTCAGTGGCCGCTCGAAGAAAAAGTAAAACGTGGTGATGCAGTTATTGACAATAACGGAACGGTGGAACAGACGCGTCG
ACAGTTATTGTCGATTTTACAACAATGGGAGGCCTTGGAAAAATAG

Upstream 100 bases:

>100_bases
TGCGGAACCCCGATTGAAAAAACGGTCGTCGCCGGCCGCGGCACGCACTATTGCCCGCACTGTCAGCGGTAGGCGACAAA
CGAAAAAGGAGAGAAATCAA

Downstream 100 bases:

>100_bases
GCGTCTTTTTTGTTTGTTTTTTGTCATTTTTCTCTCCACATTCTCGAAAAATATGATATACTATTTATACAGATTGCGAT
AAATAGTATAACATATATGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAVTIGLTGGIASGKSTVSAMMRELGLPVIDADEAARAVVEPGEEAYRQIVATFGPDILQMNGEIDRAKLGAIVFNNEQE
RKKLNAIVHPAVRRKMLAEKEELIRSGAKTVVLDIPLLFESGLTDWVDKVLVVYVDDDVQLCRLMARNGFTEEEAIARIR
AQWPLEEKVKRGDAVIDNNGTVEQTRRQLLSILQQWEALEK

Sequences:

>Translated_201_residues
MAVTIGLTGGIASGKSTVSAMMRELGLPVIDADEAARAVVEPGEEAYRQIVATFGPDILQMNGEIDRAKLGAIVFNNEQE
RKKLNAIVHPAVRRKMLAEKEELIRSGAKTVVLDIPLLFESGLTDWVDKVLVVYVDDDVQLCRLMARNGFTEEEAIARIR
AQWPLEEKVKRGDAVIDNNGTVEQTRRQLLSILQQWEALEK
>Mature_200_residues
AVTIGLTGGIASGKSTVSAMMRELGLPVIDADEAARAVVEPGEEAYRQIVATFGPDILQMNGEIDRAKLGAIVFNNEQER
KKLNAIVHPAVRRKMLAEKEELIRSGAKTVVLDIPLLFESGLTDWVDKVLVVYVDDDVQLCRLMARNGFTEEEAIARIRA
QWPLEEKVKRGDAVIDNNGTVEQTRRQLLSILQQWEALEK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=45.8762886597938, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=45.8762886597938, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI110227607, Length=197, Percent_Identity=30.9644670050761, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110227605, Length=197, Percent_Identity=30.9644670050761, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI110227603, Length=197, Percent_Identity=30.9644670050761, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI110227601, Length=197, Percent_Identity=30.9644670050761, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI205277394, Length=197, Percent_Identity=30.9644670050761, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786292, Length=208, Percent_Identity=35.5769230769231, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=41.025641025641, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25143409, Length=186, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=40.9090909090909, Blast_Score=149, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24644728, Length=189, Percent_Identity=46.031746031746, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24658602, Length=190, Percent_Identity=36.3157894736842, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22324; Mature: 22193

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTIGLTGGIASGKSTVSAMMRELGLPVIDADEAARAVVEPGEEAYRQIVATFGPDILQ
CEEEEEECCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHCCCHHHHHHHHHHHCCHHEE
MNGEIDRAKLGAIVFNNEQERKKLNAIVHPAVRRKMLAEKEELIRSGAKTVVLDIPLLFE
ECCCCCHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHH
SGLTDWVDKVLVVYVDDDVQLCRLMARNGFTEEEAIARIRAQWPLEEKVKRGDAVIDNNG
CCHHHHHHCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCEEECCCC
TVEQTRRQLLSILQQWEALEK
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVTIGLTGGIASGKSTVSAMMRELGLPVIDADEAARAVVEPGEEAYRQIVATFGPDILQ
EEEEEECCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHCCCHHHHHHHHHHHCCHHEE
MNGEIDRAKLGAIVFNNEQERKKLNAIVHPAVRRKMLAEKEELIRSGAKTVVLDIPLLFE
ECCCCCHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHH
SGLTDWVDKVLVVYVDDDVQLCRLMARNGFTEEEAIARIRAQWPLEEKVKRGDAVIDNNG
CCHHHHHHCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCEEECCCC
TVEQTRRQLLSILQQWEALEK
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA