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The map label for this gene is gapB [H]

Identifier: 138896288

GI number: 138896288

Start: 2757639

End: 2758667

Strand: Reverse

Name: gapB [H]

Synonym: GTNG_2651

Alternate gene names: 138896288

Gene position: 2758667-2757639 (Counterclockwise)

Preceding gene: 138896289

Following gene: 138896287

Centisome position: 77.7

GC content: 50.63

Gene sequence:

>1029_bases
ATGAAGGCGAAAGTGGCGATTAACGGATTCGGACGAATTGGACGGATGGTTTTCCGGAGAGCCATCAATTCTCCTGATCT
CGATATTGTGGCGGTCAATGCCAGCTATCCGCCCGAAACGTTAGCCCATTTAGTGAAATACGACTCGAACCACGGCAAAT
TTGACGGGGACGTCACCGCCTTAGAAGACGGCCTGCTTGTCAACGGAAAAAAAGTGAAGCTATTGAACTCGCGCGATCCG
CAGCAACTGCCGTGGAAAGAGCTTGATATCGATATCGTCATTGAAGCAACTGGAAAATTTAATTCTCGTGAGAAAGCGAG
CCTCCACTTAGACGCTGGGGCGAAGCGTGTCATTTTAACCGCTCCGGGCAAAAATGAGGATGTCACAATCGTCGTTGGCG
TCAACGAACAGATGCTTGATATCGAACGTCATTTCATCATTTCGAACGCTTCGTGCACGACGAACTGTCTCGCTCCTGTC
GTGAAAGTGCTTGATGAGGCGTTCGGAATTGAAAACGGGCTGATGACGACCGTTCACGCCTATACGAACGACCAAAAAAA
TATTGACAATCCGCATAAAGATTTGCGCCGCGCCCGCTCATGCGCACAATCGATCATTCCGACGACGACTGGGGCGGCGA
AAGCGCTTGGCTTAGTGTTACCGCATTTGAAAGGAAAACTTCACGGCATGGCGCTGCGCGTCCCGACGCCAAACGTCTCG
CTTGTCGATTTGGTCGTCGATGTCAAACGGGATGTGACGATTGATGAAGTGAACGAGGCGTTGCTTCGCGCGGCTAACGG
ACCGCTGAAAGGAATTTTAGAATTCACGATGGAACCGCTTGTGTCGATCGACTTCAACACGAATCCGCATTCAGCGATCA
TTGATGGTTTGTCGACGATGGTGATCGATGGACGGAAAGTGAAAGTGCTCGCTTGGTATGACAACGAATGGGGCTATTCG
TGCCGCGTCGTCGACTTAGCGCATCTTGTCGCTGCTAAGATGAACGAACATCTTCACGTCAATGCGTAA

Upstream 100 bases:

>100_bases
TTTTTTGTCATTTTTCTCTCCACATTCTCGAAAAATATGATATACTATTTATACAGATTGCGATAAATAGTATAACATAT
ATGAGAGGAGAACAAGGTGA

Downstream 100 bases:

>100_bases
CCACTTCGCCGGCCATCCGCCGGCGTTATTTTATCACCTTGAGTCAAGGTATCCCCGCTTCTCAGTGTGATGGTACGTAG
GAGGGCGTTCGCTGACTGGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKAKVAINGFGRIGRMVFRRAINSPDLDIVAVNASYPPETLAHLVKYDSNHGKFDGDVTALEDGLLVNGKKVKLLNSRDP
QQLPWKELDIDIVIEATGKFNSREKASLHLDAGAKRVILTAPGKNEDVTIVVGVNEQMLDIERHFIISNASCTTNCLAPV
VKVLDEAFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARSCAQSIIPTTTGAAKALGLVLPHLKGKLHGMALRVPTPNVS
LVDLVVDVKRDVTIDEVNEALLRAANGPLKGILEFTMEPLVSIDFNTNPHSAIIDGLSTMVIDGRKVKVLAWYDNEWGYS
CRVVDLAHLVAAKMNEHLHVNA

Sequences:

>Translated_342_residues
MKAKVAINGFGRIGRMVFRRAINSPDLDIVAVNASYPPETLAHLVKYDSNHGKFDGDVTALEDGLLVNGKKVKLLNSRDP
QQLPWKELDIDIVIEATGKFNSREKASLHLDAGAKRVILTAPGKNEDVTIVVGVNEQMLDIERHFIISNASCTTNCLAPV
VKVLDEAFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARSCAQSIIPTTTGAAKALGLVLPHLKGKLHGMALRVPTPNVS
LVDLVVDVKRDVTIDEVNEALLRAANGPLKGILEFTMEPLVSIDFNTNPHSAIIDGLSTMVIDGRKVKVLAWYDNEWGYS
CRVVDLAHLVAAKMNEHLHVNA
>Mature_342_residues
MKAKVAINGFGRIGRMVFRRAINSPDLDIVAVNASYPPETLAHLVKYDSNHGKFDGDVTALEDGLLVNGKKVKLLNSRDP
QQLPWKELDIDIVIEATGKFNSREKASLHLDAGAKRVILTAPGKNEDVTIVVGVNEQMLDIERHFIISNASCTTNCLAPV
VKVLDEAFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARSCAQSIIPTTTGAAKALGLVLPHLKGKLHGMALRVPTPNVS
LVDLVVDVKRDVTIDEVNEALLRAANGPLKGILEFTMEPLVSIDFNTNPHSAIIDGLSTMVIDGRKVKVLAWYDNEWGYS
CRVVDLAHLVAAKMNEHLHVNA

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=48.2035928143713, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=45.619335347432, Blast_Score=295, Evalue=4e-80,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=49.5468277945619, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=46.8085106382979, Blast_Score=314, Evalue=7e-87,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=49.2625368731563, Blast_Score=327, Evalue=6e-90,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=48.9675516224189, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=48.377581120944, Blast_Score=314, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=48.377581120944, Blast_Score=314, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=48.4848484848485, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=49.0909090909091, Blast_Score=327, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=48.7878787878788, Blast_Score=323, Evalue=3e-89,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=47.4474474474475, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=47.4474474474475, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=47.4474474474475, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=47.4474474474475, Blast_Score=304, Evalue=5e-83,
Organism=Drosophila melanogaster, GI19922412, Length=324, Percent_Identity=45.3703703703704, Blast_Score=288, Evalue=3e-78,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37408; Mature: 37408

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKVAINGFGRIGRMVFRRAINSPDLDIVAVNASYPPETLAHLVKYDSNHGKFDGDVTA
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEE
LEDGLLVNGKKVKLLNSRDPQQLPWKELDIDIVIEATGKFNSREKASLHLDAGAKRVILT
ECCCEEECCCEEEEECCCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEECCCCCEEEEE
APGKNEDVTIVVGVNEQMLDIERHFIISNASCTTNCLAPVVKVLDEAFGIENGLMTTVHA
CCCCCCCEEEEEECCHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQKNIDNPHKDLRRARSCAQSIIPTTTGAAKALGLVLPHLKGKLHGMALRVPTPNVS
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCE
LVDLVVDVKRDVTIDEVNEALLRAANGPLKGILEFTMEPLVSIDFNTNPHSAIIDGLSTM
EEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHCCHHE
VIDGRKVKVLAWYDNEWGYSCRVVDLAHLVAAKMNEHLHVNA
EECCCEEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MKAKVAINGFGRIGRMVFRRAINSPDLDIVAVNASYPPETLAHLVKYDSNHGKFDGDVTA
CCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEE
LEDGLLVNGKKVKLLNSRDPQQLPWKELDIDIVIEATGKFNSREKASLHLDAGAKRVILT
ECCCEEECCCEEEEECCCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEECCCCCEEEEE
APGKNEDVTIVVGVNEQMLDIERHFIISNASCTTNCLAPVVKVLDEAFGIENGLMTTVHA
CCCCCCCEEEEEECCHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQKNIDNPHKDLRRARSCAQSIIPTTTGAAKALGLVLPHLKGKLHGMALRVPTPNVS
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCE
LVDLVVDVKRDVTIDEVNEALLRAANGPLKGILEFTMEPLVSIDFNTNPHSAIIDGLSTM
EEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHCCHHE
VIDGRKVKVLAWYDNEWGYSCRVVDLAHLVAAKMNEHLHVNA
EECCCEEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]