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The map label for this gene is nagA [H]

Identifier: 138895846

GI number: 138895846

Start: 2328808

End: 2330025

Strand: Reverse

Name: nagA [H]

Synonym: GTNG_2205

Alternate gene names: 138895846

Gene position: 2330025-2328808 (Counterclockwise)

Preceding gene: 138895847

Following gene: 138895845

Centisome position: 65.63

GC content: 56.49

Gene sequence:

>1218_bases
ATGAAACGGTGGCTGTTAAAAAACGCTGTCGTGTATGCAGAAACAGGGAAAATTGACCAAGGATATGTGTTGATCGAAGG
AGAGAAAGTGGCCGATGTCGGTCCGATGTCGTTATGCCCGGCCGATGCCGGGGCGGAAGTGATCGAACTGTCCCCGCGAT
TTGCTATCGTGCCCGGATTTATTGATGTTCATATTCATGGGGCAGCCGGAGCTGATGTGATGGATGCGACGCCAGTGGCG
ATCCAGGCGATGGCCAACGCTTTACCGGCGGAAGGAACAACAAGCTTCCTAGCGACGACCATGACGGCGCCGAGTGAACA
AATCGAAGCAGCACTTGTGAATGTAGCGCGTTATATGGAGCGGGAGAACGATCCTGGGGCGGCTGAAGTGCTCGGTGTTC
ATTTGGAAGGGCCGTTTTTGTCGCCGAAGCGCGCTGGGGCACAGCACCCACGCCACCTCGCTGACCCGGACATTTCACTG
TTTCAGCGTTGGCAAGAAGTTGCCGGCGGCAATATCCGCCTTGTGACGCTCGCTCCAGAGCGGGACGGGGGGCTTGATCT
TGTCGCTTATTTAAAGAAAACGGGGGTCGTCGCCTCGATCGGCCATTCCGACGCTGTTTACGAGGAGGTGAAAGCGGCGG
TCGCTGCGGGGGTGACGCATGCCACCCACTTATTTAACGGGATGCGCGGCATTCACCACCGTGAACCGGGGGTTGCTGGT
GCGGTGCTCATGCATGATGAAGTGATGTGCGAATTGATTGCCGATGGGCTGCACGTTGCGCCGCCGATGGTTCGTTTTGC
TTACCGGAACAAAAGGAGTGATGGGCTCATCTTAATCACTGACGCTATGCGCGCTAAATGTCTCGGCGATGGGCAATACG
ATCTCGGTGGCCAGGAGGTGACTGTTCGCGGTGGAGAGGCGCGTCTTGCCGACGGCACGCTGGCAGGAAGCGTGTTAAAG
CTTGCTGATGCTCTTCGCCGTGTACTCGATTGCACTGGCTGCACCCTTGAAGAAGTGATCCGTATGGCGAGCTGGAATCC
GGCGAAACAGCTTCGCGTCCTTGATCGAAAGGGGAGTTTGCGTCCGGGGAAAGACGCCGATGTTGTCGTGCTTGATGAAC
AATACAAGGTGGCGATGACGTTTTGCCGCGGCGCACTTGCTTACTGTCAACAAAGCGAACCACAAGGGGCAGGGAGGGAT
GGTCATGAAAGTCATTGA

Upstream 100 bases:

>100_bases
CGTCGTGAAAGGAGGCGGATGGCCGCCTCTTTTTTGGTTTAGTGGTATAGACAACTAGAATATATGATGTTATGATTGTG
ATAGAAAGAGAGGGATCGAC

Downstream 100 bases:

>100_bases
GGCTATGGACTATGCAGATATGAGTCGCCAAGCAGCGAGAATGATCATCCAACAAGTTAAAGAAAAACCGAATGCCGTTC
TCGGGTTAGCAACCGGTTCG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKRWLLKNAVVYAETGKIDQGYVLIEGEKVADVGPMSLCPADAGAEVIELSPRFAIVPGFIDVHIHGAAGADVMDATPVA
IQAMANALPAEGTTSFLATTMTAPSEQIEAALVNVARYMERENDPGAAEVLGVHLEGPFLSPKRAGAQHPRHLADPDISL
FQRWQEVAGGNIRLVTLAPERDGGLDLVAYLKKTGVVASIGHSDAVYEEVKAAVAAGVTHATHLFNGMRGIHHREPGVAG
AVLMHDEVMCELIADGLHVAPPMVRFAYRNKRSDGLILITDAMRAKCLGDGQYDLGGQEVTVRGGEARLADGTLAGSVLK
LADALRRVLDCTGCTLEEVIRMASWNPAKQLRVLDRKGSLRPGKDADVVVLDEQYKVAMTFCRGALAYCQQSEPQGAGRD
GHESH

Sequences:

>Translated_405_residues
MKRWLLKNAVVYAETGKIDQGYVLIEGEKVADVGPMSLCPADAGAEVIELSPRFAIVPGFIDVHIHGAAGADVMDATPVA
IQAMANALPAEGTTSFLATTMTAPSEQIEAALVNVARYMERENDPGAAEVLGVHLEGPFLSPKRAGAQHPRHLADPDISL
FQRWQEVAGGNIRLVTLAPERDGGLDLVAYLKKTGVVASIGHSDAVYEEVKAAVAAGVTHATHLFNGMRGIHHREPGVAG
AVLMHDEVMCELIADGLHVAPPMVRFAYRNKRSDGLILITDAMRAKCLGDGQYDLGGQEVTVRGGEARLADGTLAGSVLK
LADALRRVLDCTGCTLEEVIRMASWNPAKQLRVLDRKGSLRPGKDADVVVLDEQYKVAMTFCRGALAYCQQSEPQGAGRD
GHESH
>Mature_405_residues
MKRWLLKNAVVYAETGKIDQGYVLIEGEKVADVGPMSLCPADAGAEVIELSPRFAIVPGFIDVHIHGAAGADVMDATPVA
IQAMANALPAEGTTSFLATTMTAPSEQIEAALVNVARYMERENDPGAAEVLGVHLEGPFLSPKRAGAQHPRHLADPDISL
FQRWQEVAGGNIRLVTLAPERDGGLDLVAYLKKTGVVASIGHSDAVYEEVKAAVAAGVTHATHLFNGMRGIHHREPGVAG
AVLMHDEVMCELIADGLHVAPPMVRFAYRNKRSDGLILITDAMRAKCLGDGQYDLGGQEVTVRGGEARLADGTLAGSVLK
LADALRRVLDCTGCTLEEVIRMASWNPAKQLRVLDRKGSLRPGKDADVVVLDEQYKVAMTFCRGALAYCQQSEPQGAGRD
GHESH

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=375, Percent_Identity=34.9333333333333, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI224922791, Length=377, Percent_Identity=35.2785145888594, Blast_Score=185, Evalue=8e-47,
Organism=Escherichia coli, GI1786892, Length=383, Percent_Identity=35.509138381201, Blast_Score=192, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17553768, Length=403, Percent_Identity=34.2431761786601, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=34.593023255814, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI281361140, Length=358, Percent_Identity=33.5195530726257, Blast_Score=181, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 43235; Mature: 43235

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRWLLKNAVVYAETGKIDQGYVLIEGEKVADVGPMSLCPADAGAEVIELSPRFAIVPGF
CCCCEECCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCE
IDVHIHGAAGADVMDATPVAIQAMANALPAEGTTSFLATTMTAPSEQIEAALVNVARYME
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHH
RENDPGAAEVLGVHLEGPFLSPKRAGAQHPRHLADPDISLFQRWQEVAGGNIRLVTLAPE
CCCCCCHHHEEEEEECCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
RDGGLDLVAYLKKTGVVASIGHSDAVYEEVKAAVAAGVTHATHLFNGMRGIHHREPGVAG
CCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AVLMHDEVMCELIADGLHVAPPMVRFAYRNKRSDGLILITDAMRAKCLGDGQYDLGGQEV
EEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCEE
TVRGGEARLADGTLAGSVLKLADALRRVLDCTGCTLEEVIRMASWNPAKQLRVLDRKGSL
EEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
RPGKDADVVVLDEQYKVAMTFCRGALAYCQQSEPQGAGRDGHESH
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRWLLKNAVVYAETGKIDQGYVLIEGEKVADVGPMSLCPADAGAEVIELSPRFAIVPGF
CCCCEECCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCE
IDVHIHGAAGADVMDATPVAIQAMANALPAEGTTSFLATTMTAPSEQIEAALVNVARYME
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHH
RENDPGAAEVLGVHLEGPFLSPKRAGAQHPRHLADPDISLFQRWQEVAGGNIRLVTLAPE
CCCCCCHHHEEEEEECCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCC
RDGGLDLVAYLKKTGVVASIGHSDAVYEEVKAAVAAGVTHATHLFNGMRGIHHREPGVAG
CCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AVLMHDEVMCELIADGLHVAPPMVRFAYRNKRSDGLILITDAMRAKCLGDGQYDLGGQEV
EEEHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCEE
TVRGGEARLADGTLAGSVLKLADALRRVLDCTGCTLEEVIRMASWNPAKQLRVLDRKGSL
EEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
RPGKDADVVVLDEQYKVAMTFCRGALAYCQQSEPQGAGRDGHESH
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]