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The map label for this gene is nagB [H]

Identifier: 138895845

GI number: 138895845

Start: 2328063

End: 2328827

Strand: Reverse

Name: nagB [H]

Synonym: GTNG_2204

Alternate gene names: 138895845

Gene position: 2328827-2328063 (Counterclockwise)

Preceding gene: 138895846

Following gene: 138895844

Centisome position: 65.59

GC content: 54.77

Gene sequence:

>765_bases
ATGGTCATGAAAGTCATTGAGGCTATGGACTATGCAGATATGAGTCGCCAAGCAGCGAGAATGATCATCCAACAAGTTAA
AGAAAAACCGAATGCCGTTCTCGGGTTAGCAACCGGTTCGACGGTGCTCGGTGTGTACCGTGAACTCGTTGCCGACCATC
GGCAGCACGGAACATCGTACCAGTTTGTGCGCACGGTCAATTTGGATGAGTATGTCGGGCTTGGTCCGGATCATCCGAAC
AGCTATCGCTATTATATGAATGAGCATTTGTTTTCGAATCTGGACATTCCGCTTGACGAGACGCACGTGCCGGACGGCTT
GGCCGCTGATTTAGGTGAGGAGTGCCGCCGCTATGAGCAGCTGATTGAAGGGCTAGGAGGCGTTGATTTACAGCTCTTAG
GCATCGGGCGCAACGGCCATATCGGCTTTAACGAGCCAGGGACCCCGTTTTCGTCGATGACCCATGTCGTTGAGCTTGCC
GCATCAACGCGTGAGGCGAACGCCCGCTTTTTCCCGTCATTGGATGACGTGCCGCACCACGCCATTACGATGGGGATCGC
AACCATTTTACGAAGCCGACGCATCGTGCTGCTCGCATCAGGAGCGGAAAAAGCTTCCGCGCTCGCCCGGCTGTTCGAAG
GGATCGTTTCACCTGAGCTGCCGGCTTCGGCGCTTCATCTCCATCCGGATGTCACGATCATCGCCGACCAAGAGGCGCTG
TCACTTATTCCAAACGAACAGCGGCAGGTGAAATCCCGTGATTGA

Upstream 100 bases:

>100_bases
GATGTTGTCGTGCTTGATGAACAATACAAGGTGGCGATGACGTTTTGCCGCGGCGCACTTGCTTACTGTCAACAAAGCGA
ACCACAAGGGGCAGGGAGGG

Downstream 100 bases:

>100_bases
TAAACAATCTCCTGTTCCAATTTATTACCAGCTTGAGCAATATATGAAGGAGAAAATTGAAAAAGGAGAGTGGCAGCCAG
GGGAGATGATTCCGTCTGAG

Product: N-acetylglucosamine-6-phosphate isomerase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MVMKVIEAMDYADMSRQAARMIIQQVKEKPNAVLGLATGSTVLGVYRELVADHRQHGTSYQFVRTVNLDEYVGLGPDHPN
SYRYYMNEHLFSNLDIPLDETHVPDGLAADLGEECRRYEQLIEGLGGVDLQLLGIGRNGHIGFNEPGTPFSSMTHVVELA
ASTREANARFFPSLDDVPHHAITMGIATILRSRRIVLLASGAEKASALARLFEGIVSPELPASALHLHPDVTIIADQEAL
SLIPNEQRQVKSRD

Sequences:

>Translated_254_residues
MVMKVIEAMDYADMSRQAARMIIQQVKEKPNAVLGLATGSTVLGVYRELVADHRQHGTSYQFVRTVNLDEYVGLGPDHPN
SYRYYMNEHLFSNLDIPLDETHVPDGLAADLGEECRRYEQLIEGLGGVDLQLLGIGRNGHIGFNEPGTPFSSMTHVVELA
ASTREANARFFPSLDDVPHHAITMGIATILRSRRIVLLASGAEKASALARLFEGIVSPELPASALHLHPDVTIIADQEAL
SLIPNEQRQVKSRD
>Mature_254_residues
MVMKVIEAMDYADMSRQAARMIIQQVKEKPNAVLGLATGSTVLGVYRELVADHRQHGTSYQFVRTVNLDEYVGLGPDHPN
SYRYYMNEHLFSNLDIPLDETHVPDGLAADLGEECRRYEQLIEGLGGVDLQLLGIGRNGHIGFNEPGTPFSSMTHVVELA
ASTREANARFFPSLDDVPHHAITMGIATILRSRRIVLLASGAEKASALARLFEGIVSPELPASALHLHPDVTIIADQEAL
SLIPNEQRQVKSRD

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=41.5637860082305, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI19923881, Length=243, Percent_Identity=39.917695473251, Blast_Score=178, Evalue=4e-45,
Organism=Escherichia coli, GI1786893, Length=241, Percent_Identity=37.7593360995851, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1789530, Length=236, Percent_Identity=31.7796610169492, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI48994958, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=38.4297520661157, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24581960, Length=245, Percent_Identity=42.0408163265306, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19920764, Length=245, Percent_Identity=42.0408163265306, Blast_Score=195, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 27977; Mature: 27977

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMKVIEAMDYADMSRQAARMIIQQVKEKPNAVLGLATGSTVLGVYRELVADHRQHGTSY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCE
QFVRTVNLDEYVGLGPDHPNSYRYYMNEHLFSNLDIPLDETHVPDGLAADLGEECRRYEQ
EEEEEECHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LIEGLGGVDLQLLGIGRNGHIGFNEPGTPFSSMTHVVELAASTREANARFFPSLDDVPHH
HHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AITMGIATILRSRRIVLLASGAEKASALARLFEGIVSPELPASALHLHPDVTIIADQEAL
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECHHHH
SLIPNEQRQVKSRD
HHCCCHHHHCCCCC
>Mature Secondary Structure
MVMKVIEAMDYADMSRQAARMIIQQVKEKPNAVLGLATGSTVLGVYRELVADHRQHGTSY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCE
QFVRTVNLDEYVGLGPDHPNSYRYYMNEHLFSNLDIPLDETHVPDGLAADLGEECRRYEQ
EEEEEECHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LIEGLGGVDLQLLGIGRNGHIGFNEPGTPFSSMTHVVELAASTREANARFFPSLDDVPHH
HHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
AITMGIATILRSRRIVLLASGAEKASALARLFEGIVSPELPASALHLHPDVTIIADQEAL
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEEECHHHH
SLIPNEQRQVKSRD
HHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA