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The map label for this gene is kdgR [H]

Identifier: 138895589

GI number: 138895589

Start: 2065360

End: 2066124

Strand: Reverse

Name: kdgR [H]

Synonym: GTNG_1942

Alternate gene names: 138895589

Gene position: 2066124-2065360 (Counterclockwise)

Preceding gene: 138895591

Following gene: 138895588

Centisome position: 58.2

GC content: 51.5

Gene sequence:

>765_bases
ATGAAGGAACGGATCGAAGACAGAAAACCTGAAGCCGGATTGCGCACGGTGCAGCGAGCGATCGATATTTTATATTGTTT
TACGCTAGAGGAACAAGAACTGTCGCTGACTGAAATCGCTAACAAAATTTCGTTGGCGAAATCAACGACCACTCGTCTGC
TCGCCACGCTCGAACAAAACCGTCTGGTCATCAAAAATCCGGAGACGTTGAAGTATCGACTCGGTCAAGGGTTGTATTAT
TTAGGACATATTGCTGGCAAGTCCATCGAAGTAAGAGAAATCGCTAAACCGGTGATGGAACGTCTGCGCAATGAGACACG
GGAAACGGTGAACCTATATGTGCTGGAACAAGGTGCACGCGTTTGTATTGAACAATACGAGGGGCTTCAATCGCTCCGCC
ATATGGTAAAAATCGGCGAGCGGCTGCCGCTTTGGGCGGGAGCAGGGGGAAAAGTGCTGTTGGCGTATCAATCTCCTTCG
TTTCAGGAGCGCATTTTGGCCCAAGTACCGACAGAGGAGCGACGGACTCGTTTAACCGCTGAGCTGGAGATGATCCGGCA
ACGCGGCTCTACCTCAAGTATTGACGAGCGAGAGGTCGGTTCGGCGGCGGTCGCCGCCCCGATTTTCAACATTCACGGAG
AAGTAAATGCCTGCCTATCGATCTCAGGACCGACGCACCGTTTTACGCCGCAGGCGATCCGCTGGTTTGAATCGCTAGTC
AAAGAGGGAGCCCAAACGATTTCAGAAAAGCTAGGTTACCGTTAG

Upstream 100 bases:

>100_bases
GCTTGAACGATAGTGAAATATAGTGCTAAAATGAAAACAGGCAGTTCCATCTAGAGAAAACGATTTCTGTTAAGCGGAAC
TGAAGGGAGGGAGATATGCA

Downstream 100 bases:

>100_bases
TAAGGGGGAGATCAATATGGCTATTTCAAAAGGCGCTATCAACGTGCGAAGCATATTCATCGGGGGTGAAGAGCCGTGCA
TTTGCGCTCCGGTTGTGGGG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKERIEDRKPEAGLRTVQRAIDILYCFTLEEQELSLTEIANKISLAKSTTTRLLATLEQNRLVIKNPETLKYRLGQGLYY
LGHIAGKSIEVREIAKPVMERLRNETRETVNLYVLEQGARVCIEQYEGLQSLRHMVKIGERLPLWAGAGGKVLLAYQSPS
FQERILAQVPTEERRTRLTAELEMIRQRGSTSSIDEREVGSAAVAAPIFNIHGEVNACLSISGPTHRFTPQAIRWFESLV
KEGAQTISEKLGYR

Sequences:

>Translated_254_residues
MKERIEDRKPEAGLRTVQRAIDILYCFTLEEQELSLTEIANKISLAKSTTTRLLATLEQNRLVIKNPETLKYRLGQGLYY
LGHIAGKSIEVREIAKPVMERLRNETRETVNLYVLEQGARVCIEQYEGLQSLRHMVKIGERLPLWAGAGGKVLLAYQSPS
FQERILAQVPTEERRTRLTAELEMIRQRGSTSSIDEREVGSAAVAAPIFNIHGEVNACLSISGPTHRFTPQAIRWFESLV
KEGAQTISEKLGYR
>Mature_254_residues
MKERIEDRKPEAGLRTVQRAIDILYCFTLEEQELSLTEIANKISLAKSTTTRLLATLEQNRLVIKNPETLKYRLGQGLYY
LGHIAGKSIEVREIAKPVMERLRNETRETVNLYVLEQGARVCIEQYEGLQSLRHMVKIGERLPLWAGAGGKVLLAYQSPS
FQERILAQVPTEERRTRLTAELEMIRQRGSTSSIDEREVGSAAVAAPIFNIHGEVNACLSISGPTHRFTPQAIRWFESLV
KEGAQTISEKLGYR

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=31.1023622047244, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786468, Length=253, Percent_Identity=33.596837944664, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789999, Length=264, Percent_Identity=29.5454545454545, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082359, Length=253, Percent_Identity=28.8537549407115, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786715, Length=257, Percent_Identity=29.5719844357977, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790752, Length=228, Percent_Identity=28.5087719298246, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788581, Length=245, Percent_Identity=26.1224489795918, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28766; Mature: 28766

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERIEDRKPEAGLRTVQRAIDILYCFTLEEQELSLTEIANKISLAKSTTTRLLATLEQN
CCCCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RLVIKNPETLKYRLGQGLYYLGHIAGKSIEVREIAKPVMERLRNETRETVNLYVLEQGAR
EEEEECCHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHH
VCIEQYEGLQSLRHMVKIGERLPLWAGAGGKVLLAYQSPSFQERILAQVPTEERRTRLTA
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHH
ELEMIRQRGSTSSIDEREVGSAAVAAPIFNIHGEVNACLSISGPTHRFTPQAIRWFESLV
HHHHHHHCCCCCCCCHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KEGAQTISEKLGYR
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKERIEDRKPEAGLRTVQRAIDILYCFTLEEQELSLTEIANKISLAKSTTTRLLATLEQN
CCCCCCCCCCCHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RLVIKNPETLKYRLGQGLYYLGHIAGKSIEVREIAKPVMERLRNETRETVNLYVLEQGAR
EEEEECCHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHH
VCIEQYEGLQSLRHMVKIGERLPLWAGAGGKVLLAYQSPSFQERILAQVPTEERRTRLTA
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHH
ELEMIRQRGSTSSIDEREVGSAAVAAPIFNIHGEVNACLSISGPTHRFTPQAIRWFESLV
HHHHHHHCCCCCCCCHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
KEGAQTISEKLGYR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]