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The map label for this gene is aroD

Identifier: 138895588

GI number: 138895588

Start: 2064570

End: 2065343

Strand: Reverse

Name: aroD

Synonym: GTNG_1941

Alternate gene names: 138895588

Gene position: 2065343-2064570 (Counterclockwise)

Preceding gene: 138895589

Following gene: 138895587

Centisome position: 58.17

GC content: 54.39

Gene sequence:

>774_bases
ATGGCTATTTCAAAAGGCGCTATCAACGTGCGAAGCATATTCATCGGGGGTGAAGAGCCGTGCATTTGCGCTCCGGTTGT
GGGGGTGGACGCCGAGCAAGTGTTAGCTGAGACAAGGCAAATCAGCGCGAAGAAACCGCATCTCATTGAGTGGAGAGCCG
ACTTTTTTAACGGTATCCACGATGATCGCCAAGTGGTAGCGACGGCGAAAGAGATACGGACGATCGCCGGAGATATTCCG
ATTTTGTTCACGGTCCGATCCGAGCGCGAAGGGGGAAGGCCGATTCCGTTGACGGAAGAGGAAAAAATGCGGCTGTTTGA
AACGGTGTGCCAAAGCGGAGCGATCGATTTGCTTGATTACGAGCTCGTCCATGAGCCGTATGTGGCCACCGTACGCCAGC
TTTCCCGCCAATACGGGGTGCGGCTCATTTTGTCCTACCATAATTTTGACTTCACTCCGGCCAAAGAAGAGCTCGTAGCC
AAAATGCGCCAGGCCGGGAAATATGGCGCTGATATCGCCAAAGTGGCGGTGATGCCGAAATCGCTGCAAGATGTGCTTGT
ATTATTGCAAGCGACGGAGGAAGCGCGGCAGGAGCTGCCGATTCCGCTGATTACGATGTCGATGGGGGGGCTAGGCGCCA
TTACCCGCTTGGCCGGAGGGCTGTTTGGCTCGGCAGTGACGTTTGCGGTTGGCCAGCAAAGTTCGGCCCCGGGGCAAATT
CCAATTGAGGAAGTCAAGGATGTCTTATCGGTCATCATGAAATATAGCCAATGA

Upstream 100 bases:

>100_bases
TTTACGCCGCAGGCGATCCGCTGGTTTGAATCGCTAGTCAAAGAGGGAGCCCAAACGATTTCAGAAAAGCTAGGTTACCG
TTAGTAAGGGGGAGATCAAT

Downstream 100 bases:

>100_bases
ATGAGAATTTGAGGGAGGAGAAGCCAATGGGATGTTTGCCGTTAGAAGGTGTCAAAGTGCTTGATGTTTCGACGATGATC
GCCGCACCGTTTGGCGCGGT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIHDDRQVVATAKEIRTIAGDIP
ILFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDYELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVA
KMRQAGKYGADIAKVAVMPKSLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQI
PIEEVKDVLSVIMKYSQ

Sequences:

>Translated_257_residues
MAISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIHDDRQVVATAKEIRTIAGDIP
ILFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDYELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVA
KMRQAGKYGADIAKVAVMPKSLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQI
PIEEVKDVLSVIMKYSQ
>Mature_256_residues
AISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIHDDRQVVATAKEIRTIAGDIPI
LFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDYELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVAK
MRQAGKYGADIAKVAVMPKSLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQIP
IEEVKDVLSVIMKYSQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=247, Percent_Identity=35.2226720647773, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_GEOTN (A4IPP2)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001126041.1
- ProteinModelPortal:   A4IPP2
- SMR:   A4IPP2
- STRING:   A4IPP2
- GeneID:   4966871
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_1941
- NMPDR:   fig|420246.5.peg.1866
- eggNOG:   COG0710
- HOGENOM:   HBG732926
- OMA:   SYHNFDE
- PhylomeDB:   A4IPP2
- ProtClustDB:   PRK02412
- BioCyc:   GTHE420246:GTNG_1941-MONOMER
- HAMAP:   MF_00214
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 28151; Mature: 28020

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 147-147 ACT_SITE 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIH
CCCCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHCCCC
DDRQVVATAKEIRTIAGDIPILFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDY
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHH
ELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVAKMRQAGKYGADIAKVAVMPK
HHHHCHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCHH
SLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQI
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
PIEEVKDVLSVIMKYSQ
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AISKGAINVRSIFIGGEEPCICAPVVGVDAEQVLAETRQISAKKPHLIEWRADFFNGIH
CCCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHCCCC
DDRQVVATAKEIRTIAGDIPILFTVRSEREGGRPIPLTEEEKMRLFETVCQSGAIDLLDY
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEHHHH
ELVHEPYVATVRQLSRQYGVRLILSYHNFDFTPAKEELVAKMRQAGKYGADIAKVAVMPK
HHHHCHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCHH
SLQDVLVLLQATEEARQELPIPLITMSMGGLGAITRLAGGLFGSAVTFAVGQQSSAPGQI
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
PIEEVKDVLSVIMKYSQ
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA