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The map label for this gene is dnaZX [H]

Identifier: 138893695

GI number: 138893695

Start: 25688

End: 27367

Strand: Direct

Name: dnaZX [H]

Synonym: GTNG_0016

Alternate gene names: 138893695

Gene position: 25688-27367 (Clockwise)

Preceding gene: 138893694

Following gene: 138893696

Centisome position: 0.72

GC content: 50.54

Gene sequence:

>1680_bases
GTGGCATACCAAGCGTTATACCGTGTTTTCCGGCCGCAGCGTTTTGCCGACATGGTCGGCCAAGAACACGTAACGAAAAC
ATTGCAAAGCGCCCTGCTTCAACATAAAATATCGCATGCTTACTTATTTTCCGGTCCACGTGGGACGGGAAAAACGAGTG
CGGCGAAAATTTTCGCCAAGGCGGTCAATTGTGAACATGCTCCGGCGGCCGAGCCGTGCAATGAATGTCCCGTTTGTCTC
GGCATTACGAACGGAACGGTTCCCGATGTGTTGGAAATTGACGCCGCTTCCAACAACCGTGTCGATGAAATTCGCGACAT
CCGCGAGAAAGTAAAGTTTGCACCGACTTCGGTCCGCTATAAAGTGTACATTATTGATGAAGTACACATGCTATCGATCG
GCGCGTTTAACGCACTGCTGAAAACGTTAGAAGAGCCGCCGAAACACGTCATTTTCATTTTGGCCACGACCGAGCCGCAT
AAAATTCCGGCAACAATTATTTCCCGTTGTCAACGGTTCGACTTTCGCCGCATTCCGCTATCGGCCATCGTTTCCCGGCT
GAAATACGTAGCGAATGCCCAAGGTGTGGAAGCATCTGATGAGGCGCTGTCAGCCATTGCCCGTGCCGCCGATGGGGGGA
TGCGCGATGCGCTCAGTTTACTTGATCAAGCGATTTCGTTTAGCAATGGGAAGCTTGAGGTCGACGATGTGCTGTCGATG
ACGGGGGCGGCGTCATTTGCTGCATTAGCCGACTTCATTGGAGCTATCTACCGCAAAGATACAGCTGCGGTTCTTCAGCA
GTTCGAAACAATGATGGCTCAGGGGAAAGACCCCAATCGTTTGGTGGAAGATTTAATTTTATATTGTCGCGACTTGCTGC
TCTACAAAACCGCCCCTCATGTGGAAGGAGCCATTCAAATTGCAGTCGTCGATGAGGCGTTTATCTCGCTTTCGGAAACG
ATTCCTCTTTCTGATTTATACGGAGCGATTGAGCTGTTGAACAAAAGTCAGCAAGAGATGAAATGGACGAACCACCCACG
TCTCCTTTTGGAAGTAGCGCTCGTTAGGCTTTGCCATCAGCCGGCTGCCGCGCCGTCGTTATCCGCTTCCGAGCTGGAGC
CGTTAGTGAAGCGGATTGAGACGTTAGAAGCCGAACTGCGCCGTCTGAAGGAACAACCGTCCGCTTCCCCATCGGCCGCC
GCTCCGGCGAAAAAAACGACGAAAGTGGCGAAAACCGGGGGATATAAAGCGCCAGTTGGCCGCATTCATGAACTGTTGAA
GCAAGCGACGCACGAAGATTTAGCCTTAATTAAAGGCCGCTGGGCGGACGTACTTGATACGTTGAAACGGCAGCATAAAG
TGTCGCACGCCGCCTTGCTTCAAGAGAGCGAGCCGGTTGCAGCAAGCGCCTCGGCATTTGTGTTAAAGTTTAAGTATGAA
ATCCACTGCAAAATGGCGACGGATCCGGCGAGCTCAGTGAAAGAAAATGTTGAGGCGATTTTGTTCGAAATGACGAATCG
GCGATTTGAAATGGTCGCCATTCCGGAAGAAGAATGGGGAAAAATAAGGGAAGATTTTATCCGTAACAAAGAGGCTAAAG
CAGAAAAAAGTGAGGAAGAACCGTTGATTGCCGAGGCGAAACGGCTGTTTGGTGAAGAACTGATCGAAATTAAAGAATAA

Upstream 100 bases:

>100_bases
AAACAAAACCCACTCGTAATGAGTGGGTTTTTTATTATTTTAAATTGAAACGAGAAGTTATATAATAAATAGGATGAGAG
GAAGAGGAGGGCCGTTTCCC

Downstream 100 bases:

>100_bases
ACGATTGAAGGAGGATTCCAAAATGATGCGTGGCGGAATGGGAAATATGCAAAAAATGTTAAAGCAAATGCAGAAAATGC
AAAAAGAAATGCAAAAGGCA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MAYQALYRVFRPQRFADMVGQEHVTKTLQSALLQHKISHAYLFSGPRGTGKTSAAKIFAKAVNCEHAPAAEPCNECPVCL
GITNGTVPDVLEIDAASNNRVDEIRDIREKVKFAPTSVRYKVYIIDEVHMLSIGAFNALLKTLEEPPKHVIFILATTEPH
KIPATIISRCQRFDFRRIPLSAIVSRLKYVANAQGVEASDEALSAIARAADGGMRDALSLLDQAISFSNGKLEVDDVLSM
TGAASFAALADFIGAIYRKDTAAVLQQFETMMAQGKDPNRLVEDLILYCRDLLLYKTAPHVEGAIQIAVVDEAFISLSET
IPLSDLYGAIELLNKSQQEMKWTNHPRLLLEVALVRLCHQPAAAPSLSASELEPLVKRIETLEAELRRLKEQPSASPSAA
APAKKTTKVAKTGGYKAPVGRIHELLKQATHEDLALIKGRWADVLDTLKRQHKVSHAALLQESEPVAASASAFVLKFKYE
IHCKMATDPASSVKENVEAILFEMTNRRFEMVAIPEEEWGKIREDFIRNKEAKAEKSEEEPLIAEAKRLFGEELIEIKE

Sequences:

>Translated_559_residues
MAYQALYRVFRPQRFADMVGQEHVTKTLQSALLQHKISHAYLFSGPRGTGKTSAAKIFAKAVNCEHAPAAEPCNECPVCL
GITNGTVPDVLEIDAASNNRVDEIRDIREKVKFAPTSVRYKVYIIDEVHMLSIGAFNALLKTLEEPPKHVIFILATTEPH
KIPATIISRCQRFDFRRIPLSAIVSRLKYVANAQGVEASDEALSAIARAADGGMRDALSLLDQAISFSNGKLEVDDVLSM
TGAASFAALADFIGAIYRKDTAAVLQQFETMMAQGKDPNRLVEDLILYCRDLLLYKTAPHVEGAIQIAVVDEAFISLSET
IPLSDLYGAIELLNKSQQEMKWTNHPRLLLEVALVRLCHQPAAAPSLSASELEPLVKRIETLEAELRRLKEQPSASPSAA
APAKKTTKVAKTGGYKAPVGRIHELLKQATHEDLALIKGRWADVLDTLKRQHKVSHAALLQESEPVAASASAFVLKFKYE
IHCKMATDPASSVKENVEAILFEMTNRRFEMVAIPEEEWGKIREDFIRNKEAKAEKSEEEPLIAEAKRLFGEELIEIKE
>Mature_558_residues
AYQALYRVFRPQRFADMVGQEHVTKTLQSALLQHKISHAYLFSGPRGTGKTSAAKIFAKAVNCEHAPAAEPCNECPVCLG
ITNGTVPDVLEIDAASNNRVDEIRDIREKVKFAPTSVRYKVYIIDEVHMLSIGAFNALLKTLEEPPKHVIFILATTEPHK
IPATIISRCQRFDFRRIPLSAIVSRLKYVANAQGVEASDEALSAIARAADGGMRDALSLLDQAISFSNGKLEVDDVLSMT
GAASFAALADFIGAIYRKDTAAVLQQFETMMAQGKDPNRLVEDLILYCRDLLLYKTAPHVEGAIQIAVVDEAFISLSETI
PLSDLYGAIELLNKSQQEMKWTNHPRLLLEVALVRLCHQPAAAPSLSASELEPLVKRIETLEAELRRLKEQPSASPSAAA
PAKKTTKVAKTGGYKAPVGRIHELLKQATHEDLALIKGRWADVLDTLKRQHKVSHAALLQESEPVAASASAFVLKFKYEI
HCKMATDPASSVKENVEAILFEMTNRRFEMVAIPEEEWGKIREDFIRNKEAKAEKSEEEPLIAEAKRLFGEELIEIKE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=255, Percent_Identity=26.6666666666667, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI194306571, Length=255, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI194306567, Length=255, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI31563534, Length=223, Percent_Identity=29.1479820627803, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4506491, Length=238, Percent_Identity=28.1512605042017, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI31881687, Length=238, Percent_Identity=28.1512605042017, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI194306569, Length=175, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1786676, Length=356, Percent_Identity=39.8876404494382, Blast_Score=270, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17541988, Length=223, Percent_Identity=30.0448430493274, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=222, Percent_Identity=29.2792792792793, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71986063, Length=303, Percent_Identity=22.4422442244224, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=217, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322528, Length=314, Percent_Identity=25.4777070063694, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324478, Length=236, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859927, Length=271, Percent_Identity=25.0922509225092, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17647857, Length=287, Percent_Identity=24.390243902439, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 61871; Mature: 61740

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQALYRVFRPQRFADMVGQEHVTKTLQSALLQHKISHAYLFSGPRGTGKTSAAKIFAK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHH
AVNCEHAPAAEPCNECPVCLGITNGTVPDVLEIDAASNNRVDEIRDIREKVKFAPTSVRY
HHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSIGAFNALLKTLEEPPKHVIFILATTEPHKIPATIISRCQRFDFRRIPL
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCH
SAIVSRLKYVANAQGVEASDEALSAIARAADGGMRDALSLLDQAISFSNGKLEVDDVLSM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHH
TGAASFAALADFIGAIYRKDTAAVLQQFETMMAQGKDPNRLVEDLILYCRDLLLYKTAPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
VEGAIQIAVVDEAFISLSETIPLSDLYGAIELLNKSQQEMKWTNHPRLLLEVALVRLCHQ
CCCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCC
PAAAPSLSASELEPLVKRIETLEAELRRLKEQPSASPSAAAPAKKTTKVAKTGGYKAPVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHH
RIHELLKQATHEDLALIKGRWADVLDTLKRQHKVSHAALLQESEPVAASASAFVLKFKYE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
IHCKMATDPASSVKENVEAILFEMTNRRFEMVAIPEEEWGKIREDFIRNKEAKAEKSEEE
EEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCC
PLIAEAKRLFGEELIEIKE
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYQALYRVFRPQRFADMVGQEHVTKTLQSALLQHKISHAYLFSGPRGTGKTSAAKIFAK
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHH
AVNCEHAPAAEPCNECPVCLGITNGTVPDVLEIDAASNNRVDEIRDIREKVKFAPTSVRY
HHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSIGAFNALLKTLEEPPKHVIFILATTEPHKIPATIISRCQRFDFRRIPL
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCH
SAIVSRLKYVANAQGVEASDEALSAIARAADGGMRDALSLLDQAISFSNGKLEVDDVLSM
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHH
TGAASFAALADFIGAIYRKDTAAVLQQFETMMAQGKDPNRLVEDLILYCRDLLLYKTAPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
VEGAIQIAVVDEAFISLSETIPLSDLYGAIELLNKSQQEMKWTNHPRLLLEVALVRLCHQ
CCCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCC
PAAAPSLSASELEPLVKRIETLEAELRRLKEQPSASPSAAAPAKKTTKVAKTGGYKAPVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHH
RIHELLKQATHEDLALIKGRWADVLDTLKRQHKVSHAALLQESEPVAASASAFVLKFKYE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEE
IHCKMATDPASSVKENVEAILFEMTNRRFEMVAIPEEEWGKIREDFIRNKEAKAEKSEEE
EEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHCCCCCCC
PLIAEAKRLFGEELIEIKE
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]