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The map label for this gene is tadA [H]

Identifier: 138893694

GI number: 138893694

Start: 24771

End: 25256

Strand: Direct

Name: tadA [H]

Synonym: GTNG_0015

Alternate gene names: 138893694

Gene position: 24771-25256 (Clockwise)

Preceding gene: 138893692

Following gene: 138893695

Centisome position: 0.7

GC content: 52.47

Gene sequence:

>486_bases
ATGATGAACAACGATGAGTATTACATGAGGTTAGCGATTGAAGAAGCAAAGAAAGCCGAGCAAATCGGTGAAGTGCCGAT
TGGTGCCGTCATCGTTCAAGACGGACGCGTCATCGCCCGCGCCCATAATTTGCGGGAAACGGAGCAGCGTGCCATTGCCC
ATGCGGAAATTTTAGCGATTGCTGAAGCGTGCCAGGCAACTGGTTCATGGCGGCTCGAACGAGCGACGTTGTATGTGACG
CTTGAACCATGCGCCATGTGCGCGGGGGCCATCGTCCTTTCTCGCATTGAGCGGGTTGTGTTTGGTGCCAGTGACCCAAA
AGGGGGATGCGCCGGGACGTTGATGAATTTGTTGCAAGAGAGCCGTTTTAACCATCAAGCCGACGTCACTAGCGGTGTGT
TGGCTAGCGAGTGTGGATCGTTGCTAAGCGATTTTTTTCGCCGATTGCGTGAACGAAAGAAAAATGTTGGTGGAAGTTCC
AACTAA

Upstream 100 bases:

>100_bases
TATGACATGGATTTGCATACTTGACCTCCTAGTTGCGTCTTTATTCTCCATATTTTATGATGGAAAGAGAAGAGAAATGA
CCGTTTGCACGAAGGGGTAT

Downstream 100 bases:

>100_bases
AAATCCGCCTATTTACATTGCATTTTTTCCACAAACGAGATATACTGATAGTGCCGTGCTAAGCGGGGAGGTAGCGGTGC
CCTGTACTCGCAATCCGCTC

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MMNNDEYYMRLAIEEAKKAEQIGEVPIGAVIVQDGRVIARAHNLRETEQRAIAHAEILAIAEACQATGSWRLERATLYVT
LEPCAMCAGAIVLSRIERVVFGASDPKGGCAGTLMNLLQESRFNHQADVTSGVLASECGSLLSDFFRRLRERKKNVGGSS
N

Sequences:

>Translated_161_residues
MMNNDEYYMRLAIEEAKKAEQIGEVPIGAVIVQDGRVIARAHNLRETEQRAIAHAEILAIAEACQATGSWRLERATLYVT
LEPCAMCAGAIVLSRIERVVFGASDPKGGCAGTLMNLLQESRFNHQADVTSGVLASECGSLLSDFFRRLRERKKNVGGSS
N
>Mature_161_residues
MMNNDEYYMRLAIEEAKKAEQIGEVPIGAVIVQDGRVIARAHNLRETEQRAIAHAEILAIAEACQATGSWRLERATLYVT
LEPCAMCAGAIVLSRIERVVFGASDPKGGCAGTLMNLLQESRFNHQADVTSGVLASECGSLLSDFFRRLRERKKNVGGSS
N

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=31.7880794701987, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=50.3311258278146, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI1786616, Length=156, Percent_Identity=32.0512820512821, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=42.8571428571429, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=99, Percent_Identity=35.3535353535354, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=100, Percent_Identity=40, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=32.2784810126582, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=30.8219178082192, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17582; Mature: 17582

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNDEYYMRLAIEEAKKAEQIGEVPIGAVIVQDGRVIARAHNLRETEQRAIAHAEILAI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
AEACQATGSWRLERATLYVTLEPCAMCAGAIVLSRIERVVFGASDPKGGCAGTLMNLLQE
HHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SRFNHQADVTSGVLASECGSLLSDFFRRLRERKKNVGGSSN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMNNDEYYMRLAIEEAKKAEQIGEVPIGAVIVQDGRVIARAHNLRETEQRAIAHAEILAI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHH
AEACQATGSWRLERATLYVTLEPCAMCAGAIVLSRIERVVFGASDPKGGCAGTLMNLLQE
HHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SRFNHQADVTSGVLASECGSLLSDFFRRLRERKKNVGGSSN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]