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The map label for this gene is 13508377

Identifier: 13508377

GI number: 13508377

Start: 764400

End: 765527

Strand: Direct

Name: 13508377

Synonym: MPN638

Alternate gene names: NA

Gene position: 764400-765527 (Clockwise)

Preceding gene: 13508376

Following gene: 13508390

Centisome position: 93.63

GC content: 37.77

Gene sequence:

>1128_bases
ATGACTCCTAAATTAAAGCTTAACACTAACAGTAATTGAACTAAGAAAACCCTTGGCAGCTTATTTGAACTCAAGAAGGG
TGAAATGCTCGAAAAAGAGCTATTGGCGCCCGATGGTAAATACGAATACTTTAACGGTGGTATTAAAGCCTCTGGACGCA
CCAATGAGTTCAATACCTTTAAGAACACCATTAGCATTATCATAGGCGGTTCTTGTGGTTATGTCAGATTAGCCGATAAG
GATTACTTCTGTGGCCAGAGTAGCTGTACCCTAACTGTTTTAGATCCCCTGGAAATTGACCTCAAGTTTGCTTATTATGC
ACTTAAATCACAAGAGGAAAAAATTACCAGTTTAGCTAGCGGAACTACCATTAAAAACATTCGCCTAAGTGATTTAAAGG
ATTTACCTATTCCGCTTGTTAAAAGCATTCAGGATCAACGAACTATTGCACATGCTTTAAGTGTGTTTGACCTTCGCATC
GAACACCTCAATGAATTAATTGAAGTAAACCGTAAGCTCAGAGACGAGTATGCCCACAAATTATTTACCTTAGATCCAGA
CTTCTTAACACACTGAAACCTACATGAACTCCATGAACAAATGGGTGAAATTAGTTTAGGTGAAGTGTTTCACTTAAAGA
GTGGTAAATACTTAAAGGCTGATGAGCGCTTTGAGGATGGCAAATTCCCTTATTATGGTGCTGGTATTGAAAGCACTAGC
TTTGTCAATGAACCCAACACCAAAGGTGATACTCTTTCAATGATTGCTAACGGTTACTCCATCGGAAACATTCGCTACCA
TACTATTCCTTGGTTTAATGGTACTGGTGGTATTGCCATGGAAGCATTAAAACCTAATAAAACCTATGTGCCGTTCTTTT
ACTGTGCTCTAAAATACATGCAAAAGGATCTAAAGGAACGCTTTAAACGTGATGAATCACCGTTTATTTCCTTAAAACTA
GCCGGTGAAATTAAGGTTCCTTTCGTTAAATCGTTTGCACTCCAAAGAAAAGCCGGTAAGATTATTTACTTGTTAGATAA
AACTCTTGAAGAATGCAAAGAAGAAGCTAAGTCTTTAATCAGTATTCGCGATAACTTATTGGGCAAATTGTTCCCAACAC
TATCTTAA

Upstream 100 bases:

>100_bases
ATTTACCACGTAATTGCGGGAATCTCTTCTAACCAAAGATTGCTTATGGAACCAAACACTTATTTCAGTGCTGTAAGTTA
GTTTTTAGAATTTAAAGGAA

Downstream 100 bases:

>100_bases
AGCAAAGCAAATAAGGTGTAAGGGAAAAGGTTAACACCTTCGTTATCAAAGCTCTGGTCTTTGAGACTGCTGGTTAAGCT
ATTCTCCAATAACTTCTTCA

Product: K family restriction enzyme specificity determining subunit

Products: NA

Alternate protein names: S protein [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTPKLKLNTNSNWTKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFKNTISIIIGGSCGYVRLADK
DYFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASGTTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRI
EHLNELIEVNRKLRDEYAHKLFTLDPDFLTHWNLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTS
FVNEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQKDLKERFKRDESPFISLKL
AGEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISIRDNLLGKLFPTLS

Sequences:

>Translated_375_residues
MTPKLKLNTNSN*TKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFKNTISIIIGGSCGYVRLADK
DYFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASGTTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRI
EHLNELIEVNRKLRDEYAHKLFTLDPDFLTH*NLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTS
FVNEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQKDLKERFKRDESPFISLKL
AGEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISIRDNLLGKLFPTLS
>Mature_374_residues
TPKLKLNTNSN*TKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFKNTISIIIGGSCGYVRLADKD
YFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASGTTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRIE
HLNELIEVNRKLRDEYAHKLFTLDPDFLTH*NLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTSF
VNEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQKDLKERFKRDESPFISLKLA
GEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISIRDNLLGKLFPTLS

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 42242; Mature: 42111

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKLKLNTNSNTKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFK
CCCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCEECCCCCCCHHHHC
NTISIIIGGSCGYVRLADKDYFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASG
CEEEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHCHHHHHHHHHCC
TTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRIEHLNELIEVNRKLRDEYAHKL
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FTLDPDFLTHNLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTSFV
EECCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCCCEEECCCCCCCCC
NEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQK
CCCCCCCCCHHHEECCEEECCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
DLKERFKRDESPFISLKLAGEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISI
HHHHHHCCCCCCEEEEEEECCEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
RDNLLGKLFPTLS
HHHHHHHHCCCCC
>Mature Secondary Structure 
TPKLKLNTNSNTKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFK
CCCEEECCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEECCCEECCCCCCCHHHHC
NTISIIIGGSCGYVRLADKDYFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASG
CEEEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCEEEEEEEEHHHHCHHHHHHHHHCC
TTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRIEHLNELIEVNRKLRDEYAHKL
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
FTLDPDFLTHNLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTSFV
EECCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCCCEEECCCCCCCCC
NEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQK
CCCCCCCCCHHHEECCEEECCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
DLKERFKRDESPFISLKLAGEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISI
HHHHHHCCCCCCEEEEEEECCEECCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
RDNLLGKLFPTLS
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]