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The map label for this gene is ptrB [H]

Identifier: 13476349

GI number: 13476349

Start: 6328708

End: 6330831

Strand: Reverse

Name: ptrB [H]

Synonym: mll7643

Alternate gene names: 13476349

Gene position: 6330831-6328708 (Counterclockwise)

Preceding gene: 13476352

Following gene: 13476348

Centisome position: 89.98

GC content: 62.48

Gene sequence:

>2124_bases
ATGACCAAGACTTCCCGATTTCCGATCGTCAGCCCGCCGACACCGCAGAAGCGGCCGGTTTACGAGACGCATCACGGCAT
CACGCGAACCGACGAATATGCCTGGCTGCGGGCCGACAACTGGCAAGAGATGTTTCGGGACCCCTCCCTGCTCGATGCAG
GGATCCGCGCCGAACTCGAAGCCGAGAATGCCTACCAGTCGAAGCTGATGGCCGATACTTCAGACCTGCGGAAGCAGCTT
TTCAAGGAGATGAAGGGCCGCATCAAGGAAGACGATTCTTCCGTTCCGATGAAGGACGGGCCCTATGCCTATGGGTCTTC
CTTCAAGCTTGGCGGCGAGCAGCCGCGCTATTTCCGCTTGCCGCGCGAGGGCGGAACCGAGCAGATCCTGCTCGACGGCG
ACCTCGAGGCGGAAGGCAAGGCCTATTTCCGGCTCGGCGGTGTCGACCATTCGGCCGATCACCGCAAGCTGTTGTGGGCA
TTCGACGACAAGGGTTCCGAGTTCTACACGTTGCGCGTGCGCGACCTTGCCGATGGCAAGGAACTGGCGGACCAGATTCC
CGCGACAGGCGGGTCGGGCGTTTGGGACGCAGGCAATGACGGTTTCTTCTACACCCGCCTCGATCCCAACCACCGCCCGT
CCAAGGTGCTGTTCCACGCGCTTGGACAAGACCCTGGAACCGACCGCCTGATCTATGAGGAAACCGATCCCGGCTTCTTC
ATGAATGTCGACGGCACCCGCGACAACCAATGGATCATGATCGGCATCAACGATCACGAGACTTCGGAATATCGCCTGTT
GAGCGCCAGCGATCCGTTTGCCGAACCCAAGGTTGTTTCGGCGCGCGAGACCGGCCTTCAGTATGAGCTGGAGGAAGGCG
GCGACGTCTTCTTCATCCTGACCAATGCGGACGGCGCCAAGGACTTCAAGATCATGACGGCGCCGGCAAGCGATCCGGTC
CGCGCCAACTGGCGGGAGCTGGTACCGCACGAGCCGGGCCGGCTGATCCTGTCGGTGATCGGCTTCAAGGACCATATGGT
CCGGCTCGAGCGCAAGGAGGGCCTGCCGCGCATCGTCGTGCGCGACCGTATCACTGGCGAAGAGCATCTCCTGTCTCTCG
ATGAGGAGGCTTTCTCGCTCGGCCTGTCTGGTTCCTATGAATACGACACCGAGATCATGCGCTTTTCCTATTCGTCGATG
ACGACGCCGGCGCAGGTGTTCGACTACAATATGCGCACCCGCGAACGTGCGCTGCTCAAGACCCAGGAGGTGCCATCCGG
CCACGATGCGGACCATTATGTCACCAGGCGGCTGATGGCGCCGGCCGCCGATGGCGAGCTGGTGCCGATCTCGCTTCTGC
ACCATCGAGACACGCCGCTCGACGGATCAGCCCCTTGCCTGCTCTACGGCTACGGCTCCTACGGCATCACAGTGCCGGCG
GCCTTCAACACCAACTGCCTGTCTCTGGTCGACCGCGGCTTCGTCTACGCCATCGCCCATGTCCGCGGCGGCAAGGACAA
GGGCTATGGCTGGTACGATGACGGCAAGCGGGCGCACAAGATGAACACGTTTACGGATTTCATCGCCTGTGCGCGCCATC
TCGTTGCCGAGCGCTATAGCGCGCATGACCGCATAGTCGCGCAAGGCGGCTCGGCCGGCGGCATGCTGATGGGCGCCATC
GCCAACATGGCGCCCGACTGTTTTGGCGGCATCGTCGCCGAGGTTCCCTTCGTCGACGTGCTCACCACCATGCTCGACGC
GACCTTGCCGCTGACGCCGCCGGAATGGCCGGAATGGGGCAATCCGATCGCGTCCGCCGATGACTACCGCACCATCGCCG
CCTACTCGCCTTACGACAATGTCGCGGCCCTCGACTATCCGCCGATCCTGGCGCTCGCCGGCCTCACCGATCCGCGCGTC
ACCTATTGGGAACCGGCCAAATGGGTGGCGCGGCTGCGCGACCGCAAGAGCGGCGACAATCCGGTGCTGTTCAAGATCAA
CATGGATTCCGGTCATGCCGGGGCCTCCGGCCGGTTTTCAAGGCTGGAGGAGATCGCCTATACCTATTCCTTCGCGCTGA
AGGTTACAGGCAAGGCGCAGCTTATCGAGGAGACCCTCCGATGA

Upstream 100 bases:

>100_bases
CCACCTCATGGAGCCGACACCACCCCTAGGTTACGGTCCTTGAACCCACCCTGATCGGCGTGTTCATTCATCCTTCAAGA
TAGTTCCCAAGCGAGACGCA

Downstream 100 bases:

>100_bases
TCGATTTGTCGACATCGATCGCCTATACCGCCGTCGTGCTCGGCTTTGTCTTTATTCCAGGTCCGGCCACGCTGCTGACG
ATCGCTCGGGCAACGAGTTC

Product: aminopeptidase

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MTKTSRFPIVSPPTPQKRPVYETHHGITRTDEYAWLRADNWQEMFRDPSLLDAGIRAELEAENAYQSKLMADTSDLRKQL
FKEMKGRIKEDDSSVPMKDGPYAYGSSFKLGGEQPRYFRLPREGGTEQILLDGDLEAEGKAYFRLGGVDHSADHRKLLWA
FDDKGSEFYTLRVRDLADGKELADQIPATGGSGVWDAGNDGFFYTRLDPNHRPSKVLFHALGQDPGTDRLIYEETDPGFF
MNVDGTRDNQWIMIGINDHETSEYRLLSASDPFAEPKVVSARETGLQYELEEGGDVFFILTNADGAKDFKIMTAPASDPV
RANWRELVPHEPGRLILSVIGFKDHMVRLERKEGLPRIVVRDRITGEEHLLSLDEEAFSLGLSGSYEYDTEIMRFSYSSM
TTPAQVFDYNMRTRERALLKTQEVPSGHDADHYVTRRLMAPAADGELVPISLLHHRDTPLDGSAPCLLYGYGSYGITVPA
AFNTNCLSLVDRGFVYAIAHVRGGKDKGYGWYDDGKRAHKMNTFTDFIACARHLVAERYSAHDRIVAQGGSAGGMLMGAI
ANMAPDCFGGIVAEVPFVDVLTTMLDATLPLTPPEWPEWGNPIASADDYRTIAAYSPYDNVAALDYPPILALAGLTDPRV
TYWEPAKWVARLRDRKSGDNPVLFKINMDSGHAGASGRFSRLEEIAYTYSFALKVTGKAQLIEETLR

Sequences:

>Translated_707_residues
MTKTSRFPIVSPPTPQKRPVYETHHGITRTDEYAWLRADNWQEMFRDPSLLDAGIRAELEAENAYQSKLMADTSDLRKQL
FKEMKGRIKEDDSSVPMKDGPYAYGSSFKLGGEQPRYFRLPREGGTEQILLDGDLEAEGKAYFRLGGVDHSADHRKLLWA
FDDKGSEFYTLRVRDLADGKELADQIPATGGSGVWDAGNDGFFYTRLDPNHRPSKVLFHALGQDPGTDRLIYEETDPGFF
MNVDGTRDNQWIMIGINDHETSEYRLLSASDPFAEPKVVSARETGLQYELEEGGDVFFILTNADGAKDFKIMTAPASDPV
RANWRELVPHEPGRLILSVIGFKDHMVRLERKEGLPRIVVRDRITGEEHLLSLDEEAFSLGLSGSYEYDTEIMRFSYSSM
TTPAQVFDYNMRTRERALLKTQEVPSGHDADHYVTRRLMAPAADGELVPISLLHHRDTPLDGSAPCLLYGYGSYGITVPA
AFNTNCLSLVDRGFVYAIAHVRGGKDKGYGWYDDGKRAHKMNTFTDFIACARHLVAERYSAHDRIVAQGGSAGGMLMGAI
ANMAPDCFGGIVAEVPFVDVLTTMLDATLPLTPPEWPEWGNPIASADDYRTIAAYSPYDNVAALDYPPILALAGLTDPRV
TYWEPAKWVARLRDRKSGDNPVLFKINMDSGHAGASGRFSRLEEIAYTYSFALKVTGKAQLIEETLR
>Mature_706_residues
TKTSRFPIVSPPTPQKRPVYETHHGITRTDEYAWLRADNWQEMFRDPSLLDAGIRAELEAENAYQSKLMADTSDLRKQLF
KEMKGRIKEDDSSVPMKDGPYAYGSSFKLGGEQPRYFRLPREGGTEQILLDGDLEAEGKAYFRLGGVDHSADHRKLLWAF
DDKGSEFYTLRVRDLADGKELADQIPATGGSGVWDAGNDGFFYTRLDPNHRPSKVLFHALGQDPGTDRLIYEETDPGFFM
NVDGTRDNQWIMIGINDHETSEYRLLSASDPFAEPKVVSARETGLQYELEEGGDVFFILTNADGAKDFKIMTAPASDPVR
ANWRELVPHEPGRLILSVIGFKDHMVRLERKEGLPRIVVRDRITGEEHLLSLDEEAFSLGLSGSYEYDTEIMRFSYSSMT
TPAQVFDYNMRTRERALLKTQEVPSGHDADHYVTRRLMAPAADGELVPISLLHHRDTPLDGSAPCLLYGYGSYGITVPAA
FNTNCLSLVDRGFVYAIAHVRGGKDKGYGWYDDGKRAHKMNTFTDFIACARHLVAERYSAHDRIVAQGGSAGGMLMGAIA
NMAPDCFGGIVAEVPFVDVLTTMLDATLPLTPPEWPEWGNPIASADDYRTIAAYSPYDNVAALDYPPILALAGLTDPRVT
YWEPAKWVARLRDRKSGDNPVLFKINMDSGHAGASGRFSRLEEIAYTYSFALKVTGKAQLIEETLR

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=495, Percent_Identity=29.6969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI284172413, Length=495, Percent_Identity=29.6969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI70778815, Length=495, Percent_Identity=29.6969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI284172438, Length=495, Percent_Identity=29.6969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI284172431, Length=495, Percent_Identity=29.6969696969697, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI41349456, Length=722, Percent_Identity=25.6232686980609, Blast_Score=189, Evalue=9e-48,
Organism=Homo sapiens, GI108860686, Length=218, Percent_Identity=36.697247706422, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI108860692, Length=211, Percent_Identity=36.4928909952607, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1788150, Length=687, Percent_Identity=37.9912663755458, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24583414, Length=731, Percent_Identity=23.3926128590971, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI221510989, Length=732, Percent_Identity=24.3169398907104, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78997; Mature: 78865

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSRFPIVSPPTPQKRPVYETHHGITRTDEYAWLRADNWQEMFRDPSLLDAGIRAELE
CCCCCCCCEECCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHCCCCHHCCCCEEEEE
AENAYQSKLMADTSDLRKQLFKEMKGRIKEDDSSVPMKDGPYAYGSSFKLGGEQPRYFRL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCEEEC
PREGGTEQILLDGDLEAEGKAYFRLGGVDHSADHRKLLWAFDDKGSEFYTLRVRDLADGK
CCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCHH
ELADQIPATGGSGVWDAGNDGFFYTRLDPNHRPSKVLFHALGQDPGTDRLIYEETDPGFF
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEE
MNVDGTRDNQWIMIGINDHETSEYRLLSASDPFAEPKVVSARETGLQYELEEGGDVFFIL
EECCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEHHHCCCEEEECCCCCEEEEE
TNADGAKDFKIMTAPASDPVRANWRELVPHEPGRLILSVIGFKDHMVRLERKEGLPRIVV
ECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEE
RDRITGEEHLLSLDEEAFSLGLSGSYEYDTEIMRFSYSSMTTPAQVFDYNMRTRERALLK
ECCCCCHHHHEECCHHHHEECCCCCCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHH
TQEVPSGHDADHYVTRRLMAPAADGELVPISLLHHRDTPLDGSAPCLLYGYGSYGITVPA
HHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEC
AFNTNCLSLVDRGFVYAIAHVRGGKDKGYGWYDDGKRAHKMNTFTDFIACARHLVAERYS
CCCCHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
AHDRIVAQGGSAGGMLMGAIANMAPDCFGGIVAEVPFVDVLTTMLDATLPLTPPEWPEWG
CCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
NPIASADDYRTIAAYSPYDNVAALDYPPILALAGLTDPRVTYWEPAKWVARLRDRKSGDN
CCCCCCCCCEEEEEECCCCCCEECCCCCHHEEECCCCCCCEEECHHHHHHHHHHCCCCCC
PVLFKINMDSGHAGASGRFSRLEEIAYTYSFALKVTGKAQLIEETLR
CEEEEEECCCCCCCCCCHHHHHHHHHEEEEEEEEECCHHHHHHHHCC
>Mature Secondary Structure 
TKTSRFPIVSPPTPQKRPVYETHHGITRTDEYAWLRADNWQEMFRDPSLLDAGIRAELE
CCCCCCCEECCCCCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHCCCCHHCCCCEEEEE
AENAYQSKLMADTSDLRKQLFKEMKGRIKEDDSSVPMKDGPYAYGSSFKLGGEQPRYFRL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCEEEC
PREGGTEQILLDGDLEAEGKAYFRLGGVDHSADHRKLLWAFDDKGSEFYTLRVRDLADGK
CCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCHH
ELADQIPATGGSGVWDAGNDGFFYTRLDPNHRPSKVLFHALGQDPGTDRLIYEETDPGFF
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEE
MNVDGTRDNQWIMIGINDHETSEYRLLSASDPFAEPKVVSARETGLQYELEEGGDVFFIL
EECCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEHHHCCCEEEECCCCCEEEEE
TNADGAKDFKIMTAPASDPVRANWRELVPHEPGRLILSVIGFKDHMVRLERKEGLPRIVV
ECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEE
RDRITGEEHLLSLDEEAFSLGLSGSYEYDTEIMRFSYSSMTTPAQVFDYNMRTRERALLK
ECCCCCHHHHEECCHHHHEECCCCCCCCCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHH
TQEVPSGHDADHYVTRRLMAPAADGELVPISLLHHRDTPLDGSAPCLLYGYGSYGITVPA
HHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEC
AFNTNCLSLVDRGFVYAIAHVRGGKDKGYGWYDDGKRAHKMNTFTDFIACARHLVAERYS
CCCCHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
AHDRIVAQGGSAGGMLMGAIANMAPDCFGGIVAEVPFVDVLTTMLDATLPLTPPEWPEWG
CCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
NPIASADDYRTIAAYSPYDNVAALDYPPILALAGLTDPRVTYWEPAKWVARLRDRKSGDN
CCCCCCCCCEEEEEECCCCCCEECCCCCHHEEECCCCCCCEEECHHHHHHHHHHCCCCCC
PVLFKINMDSGHAGASGRFSRLEEIAYTYSFALKVTGKAQLIEETLR
CEEEEEECCCCCCCCCCHHHHHHHHHEEEEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]